Chronic Non Specific Low Back PainMCD-RP-NSCLBPNCT07013786
Correlation Between Motor Control Dysfunction and Radiographic Parameter in Non Specific Chronic Low Back Pain
An observational study of Chronic Non Specific Low Back Pain, run by Mohammad Abdelazeem Darwish Saad.
Trial summary
This study aims to investigate the relationship between motor control dysfunction (MCD) and radiographic parameters in non-specific chronic low back pain (NSCLBP). Participants will undergo specific clinical motor control tests and lumbar spine X-rays to evaluate the alignment and coordination of spinal and pelvic… Read more about this study
- Who is it for?
- Ages 20 to 40 years
- Conditions the study is for
- Chronic Non Specific Low Back Pain
- What is being tested?
- Pressure biofeedback assessment
- How many people
- 64 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2025to 30 Jul 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- All sexes
- No healthy volunteers
- Adult
Study population: Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP), recruited from the outpatient physical therapy clinic of Cairo University. Participants will be screened based on clinical and radiographic criteria to ensure eligibility and safety.
Who may be able to join
- . Patients diagnosed with non-specific chronic low back pain (NSCLBP) for more than 3 months
- Age between 20 and 40 years
- Both males and females
- Body mass index (BMI) between 18.5 and 29.9
- No physical therapy or medical treatment during the last 3 months
- Able and willing to provide informed consent
Who cannot join
- • Patients with specific causes of low back pain (e.g., disc herniation, fractures, tumors, infections)
- History of spinal or lower limb surgery or injury
- Radiculopathy or neurological disorders affecting motor control
- Diagnosed spinal deformities (e.g., scoliosis, spondyloarthropathy, ankylosing spondylitis)
- Contraindications to X-ray (e.g., pregnancy)
- Patients currently undergoing physical therapy or medical intervention
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Mahmoud Mohammad Ali, Phd,MSc,PSc contact
About this study
This study aims to investigate the relationship between motor control dysfunction (MCD) and radiographic parameters in non-specific chronic low back pain (NSCLBP). Participants will undergo specific clinical motor control tests and lumbar spine X-rays to evaluate the alignment and coordination of spinal and pelvic structures. Understanding this relationship may help improve rehabilitation strategies and reduce pain in affected individuals.
Read the detailed description
Non-specific chronic low back pain (NSCLBP) is a common musculoskeletal condition associated with impaired neuromuscular coordination and motor control dysfunction (MCD). This study seeks to determine the correlation between MCD and radiographic parameters including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA).
A total of 64 participants aged 20-40 with NSCLBP will be evaluated at the Faculty of Physical Therapy, Cairo University. Motor control will be assessed using a pressure biofeedback unit in two positions (crock lying and prone) via the Abdominal Draw-in Maneuver (ADIM). Radiographic measurements will be taken using lateral lumbar spine X-rays in standing posture.
The aim is to identify whether poor activation of deep stabilizing muscles (Transverse Abdominus and Multifidus) correlates with abnormal pelvic alignment and altered spinal curvature. Outcomes may support more effective personalized rehabilitation protocols targeting neuromuscular control to improve spine-pelvis function in NSCLBP patients.
Statistical analysis will include Pearson correlation to test for associations between motor control test performance and radiographic angle values.
- Conditions
- Chronic Non Specific Low Back Pain
- Being tested
- Pressure biofeedback assessment
- Keywords
- Lumbar motor control dysfunction, Lumbopelvic parameters, Radiographic alignment, Transverse abdominis, Multifidus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pressure biofeedback assessmentDiagnostic test
Participants will be assessed for lumbar motor control using a pressure biofeedback unit (PBU) during the Abdominal Draw-In Maneuver (ADIM) in both crock lying and prone positions. This is a non-invasive test to evaluate deep core muscle function (TrA and MF) in patients with NSCLBP. No therapeutic intervention will be administered.
| Study group | Role | What they receive |
|---|---|---|
| NSCLBP Patients | Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP). Participants will undergo assessment of lumbar motor control using a pressure biofeedback unit in two positions (crock lying and prone). Additionally, radiographic imaging will be performed to measure lumbopelvic parameters, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA), to analyze their correlation with motor control dysfunction. Receives: Diagnostic Test: Pressure biofeedback assessment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Lumbar Lordotic Angle
Radiographic measurement of the lumbar lordotic angle (LLA) in degrees to assess sagittal spinal alignment in patients diagnosed with non-specific chronic low back pain.
Measured: At baseline (during initial assessment visit)
Pelvic Incidence Angle
Measurement of Pelvic Incidence Angle in degrees obtained from lateral radiographic imaging in patients with non-specific chronic low back pain.
Measured: At baseline (during initial assessment visit)
Pelvic Tilt Angle
Assessment of pelvic tilt angle in degrees as part of the evaluation of lumbopelvic alignment in patients with non-specific chronic low back pain.
Measured: At baseline (during initial assessment visit)
Sacral Slope Angle
Evaluation of sacral slope angle in degrees based on standard radiographic imaging in patients with non-specific chronic low back pain.
Measured: At baseline (during initial assessment visit)
Lumbar Motor Control Assessment via Pressure Biofeedback during ADIM
Evaluation of lumbar motor control using pressure biofeedback during the Abdominal Draw-In Maneuver (ADIM) from crook lying and prone position. Pressure changes in mmHg will be recorded to assess the ability to maintain abdominal contraction.
Measured: At baseline (during initial assessment visit)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Jun 2025
- Study start1 Jun 2025 (estimated)
- Primary completion30 Jun 2025 (estimated)
- Study completion30 Jul 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Chronic Non Specific Low Back PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 64 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mohammad Abdelazeem Darwish Saad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Mohammad Abdelazeem Darwish Saad, Cairo University
- Investigators
- Enas Fawzy Youssef, Phd,MSc,PSc, Principal investigator, Cairo university- Faculty of physical therapyNevien Ezzat Elliethy, Phd,MSc,PSc, Principal investigator, Cairo university- faculty of medicine,department of radiologyTasneem Ehab Mohammad, Phd,MSc,PSc, Principal investigator, Cairo university- Faculty of physical therapy
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07013786
- Sponsor's protocol ID
- CUFPT-TRIAL001
- Acronym
- MCD-RP-NSCLBP
- Status last verified
- Jun 2025
- First submitted
- 30 May 2025
- Last updated
- 10 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared due to privacy concerns and institutional policy. The study is conducted as part of an academic thesis and is not intended for open data sharing.
Publications
Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.
PubMed 26742533
Study at a glance
From the registry record, last updated by the sponsor on 10 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Motor Control Dysfunction and Radiographic Parameter in Non Specific Chronic Low Back Pain
- ClinicalTrials.gov ID
- NCT07013786
- Acronym / sponsor ID
- MCD-RP-NSCLBP / CUFPT-TRIAL001
- Conditions
- Chronic Non Specific Low Back Pain
- Keywords
- Lumbar motor control dysfunction, Lumbopelvic parameters, Radiographic alignment, Transverse abdominis, Multifidus
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 64 participants (estimated)
- Lead sponsor
- Mohammad Abdelazeem Darwish SaadUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 30 Jun 2025 (estimated)
- Study completion
- 30 Jul 2025 (estimated)
- First posted
- 10 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the relationship between motor control dysfunction (MCD) and radiographic parameters in non-specific chronic low back pain (NSCLBP). Participants will undergo specific clinical motor control tests and lumbar spine X-rays to evaluate the alignment and coordination of spinal and pelvic structures. Understanding this relationship may help improve rehabilitation strategies and reduce pain in affected individuals.
Detailed description
Non-specific chronic low back pain (NSCLBP) is a common musculoskeletal condition associated with impaired neuromuscular coordination and motor control dysfunction (MCD). This study seeks to determine the correlation between MCD and radiographic parameters including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA).
A total of 64 participants aged 20-40 with NSCLBP will be evaluated at the Faculty of Physical Therapy, Cairo University. Motor control will be assessed using a pressure biofeedback unit in two positions (crock lying and prone) via the Abdominal Draw-in Maneuver (ADIM). Radiographic measurements will be taken using lateral lumbar spine X-rays in standing posture.
The aim is to identify whether poor activation of deep stabilizing muscles (Transverse Abdominus and Multifidus) correlates with abnormal pelvic alignment and altered spinal curvature. Outcomes may support more effective personalized rehabilitation protocols targeting neuromuscular control to improve spine-pelvis function in NSCLBP patients.
Statistical analysis will include Pearson correlation to test for associations between motor control test performance and radiographic angle values.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| NSCLBP Patients | – | Diagnostic Test: Pressure biofeedback assessmentPatients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP). Participants will undergo assessment of lumbar motor control using a pressure biofeedback unit in two positions (crock lying and prone). Additionally, radiographic imaging will be performed to measure lumbopelvic parameters, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA), to analyze their correlation with motor control dysfunction. |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP), recruited from the outpatient physical therapy clinic of Cairo University. Participants will be screened based on clinical and radiographic criteria to ensure eligibility and safety.
Key inclusion criteria (6 listed)
- . Patients diagnosed with non-specific chronic low back pain (NSCLBP) for more than 3 months
Key exclusion criteria (6 listed)
- • Patients with specific causes of low back pain (e.g., disc herniation, fractures, tumors, infections)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pressure biofeedback assessmentParticipants will be assessed for lumbar motor control using a pressure biofeedback unit (PBU) during the Abdominal Draw-In Maneuver (ADIM) in both crock lying and prone positions. This is a non-invasive test to evaluate deep core muscle function (TrA and MF) in patients with NSCLBP. No therapeutic intervention will be administered. | Diagnostic test | NSCLBP Patients |
Primary outcome
Lumbar Lordotic Angle
Time frame: At baseline (during initial assessment visit)
Radiographic measurement of the lumbar lordotic angle (LLA) in degrees to assess sagittal spinal alignment in patients diagnosed with non-specific chronic low back pain.
Pelvic Incidence Angle
Time frame: At baseline (during initial assessment visit)
Measurement of Pelvic Incidence Angle in degrees obtained from lateral radiographic imaging in patients with non-specific chronic low back pain.
Pelvic Tilt Angle
Time frame: At baseline (during initial assessment visit)
Assessment of pelvic tilt angle in degrees as part of the evaluation of lumbopelvic alignment in patients with non-specific chronic low back pain.
Sacral Slope Angle
Time frame: At baseline (during initial assessment visit)
Evaluation of sacral slope angle in degrees based on standard radiographic imaging in patients with non-specific chronic low back pain.
Lumbar Motor Control Assessment via Pressure Biofeedback during ADIM
Time frame: At baseline (during initial assessment visit)
Evaluation of lumbar motor control using pressure biofeedback during the Abdominal Draw-In Maneuver (ADIM) from crook lying and prone position. Pressure changes in mmHg will be recorded to assess the ability to maintain abdominal contraction.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Jun 2025.
- Background: PubMed 26742533Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared due to privacy concerns and institutional policy. The study is conducted as part of an academic thesis and is not intended for open data sharing.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mahmoud Mohammad Ali, Phd,MSc,PSc contact
Enas Fawzy Youssef, Phd,MSc,PSc principal investigator
Cairo university- Faculty of physical therapy
Nevien Ezzat Elliethy, Phd,MSc,PSc principal investigator
Cairo university- faculty of medicine,department of radiology
Tasneem Ehab Mohammad, Phd,MSc,PSc principal investigator
Cairo university- Faculty of physical therapy
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Non Specific Low Back Pain, run by Mohammad Abdelazeem Darwish Saad.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 10 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mohammad Abdelazeem Saad, MSc, BSc (01008926933, Saad.mohabd@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Lumbar Lordotic Angle (time frame: At baseline (during initial assessment visit)). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07013786, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Jun 2025.