Infection Due to Coronary Artery Bypass Graft (Diagnosis)NCT07003750
Surgical Wound Infection Prevention Bundle in Patients Undergoing Coronary Bypass Graft Surgery
A study testing Surgical wound infection prevention bundle in people with Infection Due to Coronary Artery Bypass Graft (Diagnosis), run by Sohag University at 1 site in Egypt.
Trial summary
estimate the utilization of locally customized surgical wound infection bundle to prevent and or control of infection in patients undergoing CABG surgery in Sohag Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Infection Due to Coronary Artery Bypass Graft (Diagnosis)
- What is being tested?
- Surgical wound infection prevention bundle
- Type of treatment
- Injection or infusion
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jul 2025to 30 Jun 2026
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- coronary artery disease ,diebetes mellitus,hypertension,
Who cannot join
- patients who have cancer , immunocompromised patients, cardiac surgeries other than CABG
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Surgical Wound Infection Prevention Bundle in Patients Undergoing Coronary Bypass Graft Surgery Sohag Experience
estimate the utilization of locally customized surgical wound infection bundle to prevent and or control of infection in patients undergoing CABG surgery in Sohag
- Being tested
- Surgical wound infection prevention bundle
- Medical subject headings
- Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Surgical wound infection prevention bundleOther
utilization of locally customized surgical wound infection bundle to prevent and or control of infection in patients undergoing CABG surgery
| Study group | Role | What they receive |
|---|---|---|
| group 1 | Active comparator | * Preoperative:
1. Nightly CHG baths
2. Mupirocin nasal ointment twice daily for 2 to 5 days prior to surgery
3. Hair removal with clippers
* Intraoperative:
1. Skin antisepsis with CHG solution
2. Standardized IV antibiotic doses at the following time points :within 5 to 60 minutes of the initial surgical incision, with initiation of cardiopulmonary bypass ,and every 3 hours intraoperatively for the duration of the case.
* Postoperative :
1. The occlusive sternal dressing applied at time of chest closure and removed 48 hours postoperatively then daily dressing thereafter.
2. Daily postoperative linen change and minimize sternotomy exposure to home blankets Receives: Other: Surgical wound infection prevention bundle |
| group 2 | No intervention | * Preoperative: 1. Preoperative water and soap bath 2. Hair removal with razor * Intraoperative: 1. Skin antisepsis with betadine solution 2. One dose of antibiotic just before skin incision * Postoperative: 1. The occlusive sternal dressing removed 72 hours postoperatively then daily dressing 2. No specific concerns about linens change and home blankets exposure |
What is being measured
The primary outcome is the main question the study is designed to answer.
surgical site wound infection
Early complications including superficial and deep surgical site infection. Late complications including DSWI, systemic and chronic sinus
Measured: From enrollment to 6 months after surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jun 2025
- Study start1 Jul 2025
- Primary completion30 Mar 2026
- Study completion30 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Infection Due to Coronary Artery Bypass Graft (Diagnosis)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 200 participants (actual)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Ragab Mostafa, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07003750
- Sponsor's protocol ID
- soh-Med--25-4-05MS
- Status last verified
- Jul 2026
- First submitted
- 8 May 2025
- Last updated
- 9 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No