GeriatricsGICUNCT07001410
Geriatrics in the Intensive Care Unit
An observational study of Geriatrics, run by Hospital Departamental de Villavicencio at 1 site in Colombia.
Trial summary
Life expectancy is longer in populations of medium- and high-income countries. Older adults are an increasingly large population in intensive care units (ICUs). There are limited publications about the epidemiology, benefits, expenditure, and outcomes of elderly and very old critically ill patients. Read more about this study
- Who is it for?
- Ages 18 to 120 years
- Conditions the study is for
- Geriatrics
- What is being tested?
- Age group
- How many people
- 1,000 participants
- Where
- 1 siteColombia
- Study dates
- Dec 2026to Dec 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 120 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults discharged from the intensive care unit during the study period, especially older adults and octogenarians.
Who may be able to join
- Registry of adults older than 18 years, discharged from the critical care unit.
Who cannot join
- None.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Colombia1 site
Hospital Departamental de Villavicencio
Villavicencio, Meta Department, 50001
About this study
Official title: Geriatrics in the Intensive Care Unit. An Observational Clinical Trial
Life expectancy is longer in populations of medium- and high-income countries. Older adults are an increasingly large population in intensive care units (ICUs). There are limited publications about the epidemiology, benefits, expenditure, and outcomes of elderly and very old critically ill patients.
We are designing a study to characterize older adults admitted to the intensive care unit and determine factors associated with adverse outcomes. The discharge registry of the ICU of a third-level hospital was reviewed. Records from January to December 2024 were reviewed. Three age groups were selected for comparison: A. <65 years; B. 65-79 years; C. 80 years and above. The outcomes to compare will be: mortality, need for invasive mechanical ventilation, ICU length of stay, and duration of mechanical ventilation.
Read the detailed description
Background: Older adults represent a significant and increasing proportion of patients admitted to the intensive care unit, as the population's life expectancy is longer. The study aims to investigate factors associated with mortality in geriatric patients receiving critical care.
Methodology: We are designing a retrospective analytical cross-sectional clinical trial. The discharge records from January to December 2024 of one of the intensive care units (ICUs) from the Orinoco region in Colombia will be reviewed. The records will be divided into three groups for comparison: A. Lower than 65 years; B. between 65 and 79 years; C. 80 years and older. The records of patients admitted to the intermediate unit will be excluded. Outcomes to be evaluated will include mortality, ICU length of stay, invasive mechanical ventilation (IMV), and duration of IMV. The data will be exported to Excel. The frequency and proportion of categorical variables will be described. The central distribution and dispersion of quantitative variables will also be defined. Chi-square and Mann-Whitney U tests will be used for the statistical comparison of the variables. A value <0.05 of p will be designated as statistical significance.
Results: The frequency of older adults admitted to the ICU will be revealed at the end of the study. The outcomes and factors associated with mortality by age groups will be discriminated.
Conclusions: The study is feasible, pertinent, affordable, and essential for the region, as it will optimize resource planning and improve healthcare for critically ill older adults.
- Conditions
- Geriatrics
- Being tested
- Age group
- Keywords
- Aged, Frail Older Adults, Intensive Care Units, Critical Illness, Colombia
- Medical subject headings
- Critical Illness
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Age groupOther
Observation of the outcomes by age groups.
| Study group | Role | What they receive |
|---|---|---|
| Younger adults | Critically ill patients, younger adults (<65 years) Receives: Other: Age group | |
| Elders | Critically ill old patients (aged 65 to 79 years) Receives: Other: Age group | |
| Octogenarians | Very old critically ill patients (80 years old or more) Receives: Other: Age group |
What is being measured
The primary outcome is the main question the study is designed to answer.
ICU mortality
Mortality during ICU stay.
Measured: 30 days
Secondary outcomes (3)
ICU length of stay
Duration of stay in the intensive care unit
Measured: 30 days
Invasive mechanical ventilation
Need of mechanical ventilation
Measured: 30 days
Duration of IMV
Duration of the invasive mechanical ventilation
Measured: 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2025
- Study startDec 2026 (estimated)
- Primary completionJul 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (12)Papers the sponsor has linked to this study.
- Other trials for GeriatricsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 1,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hospital Departamental de Villavicencio
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Norton Perez-Gutierrez, MD, Hospital Departamental de Villavicencio
- Investigators
- Norton Perez, MD, Principal investigator, Hospital Departamental de Villavicencio
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07001410
- Sponsor's protocol ID
- GRIVI_2025_01_UCI_GERIATR
- Acronym
- GICU
- Status last verified
- Feb 2026
- First submitted
- 23 May 2025
- Last updated
- 9 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Heppner HJ, Haitham H. Intensive care of geriatric patients-a thin line between under- and overtreatment. Wien Med Wochenschr. 2022 Apr;172(5-6):102-108. doi: 10.1007/s10354-021-00902-1. Epub 2022 Jan 10.
PubMed 35006520Ball IM, Bagshaw SM, Burns KE, Cook DJ, Day AG, Dodek PM, Kutsogiannis DJ, Mehta S, Muscedere JG, Turgeon AF, Stelfox HT, Wells GA, Stiell IG. Outcomes of elderly critically ill medical and surgical patients: a multicentre cohort study. Can J Anaesth. 2017 Mar;64(3):260-269. doi: 10.1007/s12630-016-0798-4. Epub 2016 Dec 27.
PubMed 28028673Beil M, Flaatten H, Guidet B, Sviri S, Jung C, de Lange D, Leaver S, Fjolner J, Szczeklik W, van Heerden PV. The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care? Crit Care. 2021 Sep 10;25(1):330. doi: 10.1186/s13054-021-03750-y.
PubMed 34507597Beil M, Sviri S, Flaatten H, De Lange DW, Jung C, Szczeklik W, Leaver S, Rhodes A, Guidet B, van Heerden PV. On predictions in critical care: The individual prognostication fallacy in elderly patients. J Crit Care. 2021 Feb;61:34-38. doi: 10.1016/j.jcrc.2020.10.006. Epub 2020 Oct 13.
PubMed 33075607Shum HP, Chan KC, Wong HY, Yan WW. Outcome of elderly patients who receive intensive care at a regional hospital in Hong Kong. Hong Kong Med J. 2015 Dec;21(6):490-8. doi: 10.12809/hkmj144445. Epub 2015 Sep 29.
PubMed 26416174Rai S, Brace C, Ross P, Darvall J, Haines K, Mitchell I, van Haren F, Pilcher D. Characteristics and Outcomes of Very Elderly Patients Admitted to Intensive Care: A Retrospective Multicenter Cohort Analysis. Crit Care Med. 2023 Oct 1;51(10):1328-1338. doi: 10.1097/CCM.0000000000005943. Epub 2023 May 23.
PubMed 37219961Vincent JL, Creteur J. Appropriate care for the elderly in the ICU. J Intern Med. 2022 Apr;291(4):458-468. doi: 10.1111/joim.13371. Epub 2021 Oct 5.
PubMed 34487587Andersen FH, Ariansen Haaland O, Klepstad P, Flaatten H. Frailty and survival in elderly intensive care patients in Norway. Acta Anaesthesiol Scand. 2021 Sep;65(8):1065-1072. doi: 10.1111/aas.13836. Epub 2021 May 7.
PubMed 33896003Ramos JGR, Ranzani OT, Perondi B, Dias RD, Jones D, Carvalho CRR, Velasco IT, Forte DN. A decision-aid tool for ICU admission triage is associated with a reduction in potentially inappropriate intensive care unit admissions. J Crit Care. 2019 Jun;51:77-83. doi: 10.1016/j.jcrc.2019.02.002. Epub 2019 Feb 4.
PubMed 30769294Kim J, Choi SM, Park YS, Lee CH, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Lee J. Factors influencing the initiation of intensive care in elderly patients and their families: A retrospective cohort study. Palliat Med. 2016 Sep;30(8):789-99. doi: 10.1177/0269216316634241. Epub 2016 Mar 2.
PubMed 26934945Haas LEM, van Beusekom I, van Dijk D, Hamaker ME, Bakhshi-Raiez F, de Lange DW, de Keizer NF. Healthcare-related costs in very elderly intensive care patients. Intensive Care Med. 2018 Nov;44(11):1896-1903. doi: 10.1007/s00134-018-5381-8. Epub 2018 Sep 25.
PubMed 30255319Ferretti-Rebustini REL, Bispo NDS, Alves WDS, Dias TN, Santoro CM, Padilha KG. Level of acuity, severity and intensity of care of adults and older adults admitted to the Intensive Care Unit. Rev Esc Enferm USP. 2019 Jan 21;53:e03416. doi: 10.1590/S1980-220X2017051403416. English, Portuguese.
PubMed 30673049
Study at a glance
From the registry record, last updated by the sponsor on 9 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Geriatrics in the Intensive Care Unit. An Observational Clinical Trial
- ClinicalTrials.gov ID
- NCT07001410
- Acronym / sponsor ID
- GICU / GRIVI_2025_01_UCI_GERIATR
- Conditions
- Geriatrics
- Keywords
- Aged, Frail Older Adults, Intensive Care Units, Critical Illness, Colombia
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,000 participants (estimated)
- Lead sponsor
- Hospital Departamental de VillavicencioUniversity, hospital or other
- Study start
- Dec 2026 (estimated)
- Primary completion
- Jul 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 3 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Life expectancy is longer in populations of medium- and high-income countries. Older adults are an increasingly large population in intensive care units (ICUs). There are limited publications about the epidemiology, benefits, expenditure, and outcomes of elderly and very old critically ill patients.
We are designing a study to characterize older adults admitted to the intensive care unit and determine factors associated with adverse outcomes. The discharge registry of the ICU of a third-level hospital was reviewed. Records from January to December 2024 were reviewed. Three age groups were selected for comparison: A. <65 years; B. 65-79 years; C. 80 years and above. The outcomes to compare will be: mortality, need for invasive mechanical ventilation, ICU length of stay, and duration of mechanical ventilation.
Detailed description
Background: Older adults represent a significant and increasing proportion of patients admitted to the intensive care unit, as the population's life expectancy is longer. The study aims to investigate factors associated with mortality in geriatric patients receiving critical care.
Methodology: We are designing a retrospective analytical cross-sectional clinical trial. The discharge records from January to December 2024 of one of the intensive care units (ICUs) from the Orinoco region in Colombia will be reviewed. The records will be divided into three groups for comparison: A. Lower than 65 years; B. between 65 and 79 years; C. 80 years and older. The records of patients admitted to the intermediate unit will be excluded. Outcomes to be evaluated will include mortality, ICU length of stay, invasive mechanical ventilation (IMV), and duration of IMV. The data will be exported to Excel. The frequency and proportion of categorical variables will be described. The central distribution and dispersion of quantitative variables will also be defined. Chi-square and Mann-Whitney U tests will be used for the statistical comparison of the variables. A value <0.05 of p will be designated as statistical significance.
Results: The frequency of older adults admitted to the ICU will be revealed at the end of the study. The outcomes and factors associated with mortality by age groups will be discriminated.
Conclusions: The study is feasible, pertinent, affordable, and essential for the region, as it will optimize resource planning and improve healthcare for critically ill older adults.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Younger adults | – | Other: Age groupCritically ill patients, younger adults (<65 years) |
| Elders | – | Other: Age groupCritically ill old patients (aged 65 to 79 years) |
| Octogenarians | – | Other: Age groupVery old critically ill patients (80 years old or more) |
Who may qualify
- Ages
- 18 to 120 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults discharged from the intensive care unit during the study period, especially older adults and octogenarians.
Key inclusion criteria (1 listed)
- Registry of adults older than 18 years, discharged from the critical care unit.
Key exclusion criteria (1 listed)
- None.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Age groupObservation of the outcomes by age groups. | Other | Elders, Octogenarians, Younger adults |
Primary outcome
ICU mortality
Time frame: 30 days
Mortality during ICU stay.
3 secondary outcomes
ICU length of stay
Time frame: 30 days
Invasive mechanical ventilation
Time frame: 30 days
Duration of IMV
Time frame: 30 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Feb 2026.
- Results publication: PubMed 35006520Heppner HJ, Haitham H. Intensive care of geriatric patients-a thin line between under- and overtreatment. Wien Med Wochenschr. 2022 Apr;172(5-6):102-108. doi: 10.1007/s10354-021-00902-1. Epub 2022 Jan 10.
- Results publication: PubMed 28028673Ball IM, Bagshaw SM, Burns KE, Cook DJ, Day AG, Dodek PM, Kutsogiannis DJ, Mehta S, Muscedere JG, Turgeon AF, Stelfox HT, Wells GA, Stiell IG. Outcomes of elderly critically ill medical and surgical patients: a multicentre cohort study. Can J Anaesth. 2017 Mar;64(3):260-269. doi: 10.1007/s12630-016-0798-4. Epub 2016 Dec 27.
- Results publication: PubMed 34507597Beil M, Flaatten H, Guidet B, Sviri S, Jung C, de Lange D, Leaver S, Fjolner J, Szczeklik W, van Heerden PV. The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care? Crit Care. 2021 Sep 10;25(1):330. doi: 10.1186/s13054-021-03750-y.
- Results publication: PubMed 33075607Beil M, Sviri S, Flaatten H, De Lange DW, Jung C, Szczeklik W, Leaver S, Rhodes A, Guidet B, van Heerden PV. On predictions in critical care: The individual prognostication fallacy in elderly patients. J Crit Care. 2021 Feb;61:34-38. doi: 10.1016/j.jcrc.2020.10.006. Epub 2020 Oct 13.
- Results publication: PubMed 26416174Shum HP, Chan KC, Wong HY, Yan WW. Outcome of elderly patients who receive intensive care at a regional hospital in Hong Kong. Hong Kong Med J. 2015 Dec;21(6):490-8. doi: 10.12809/hkmj144445. Epub 2015 Sep 29.
- Results publication: PubMed 37219961Rai S, Brace C, Ross P, Darvall J, Haines K, Mitchell I, van Haren F, Pilcher D. Characteristics and Outcomes of Very Elderly Patients Admitted to Intensive Care: A Retrospective Multicenter Cohort Analysis. Crit Care Med. 2023 Oct 1;51(10):1328-1338. doi: 10.1097/CCM.0000000000005943. Epub 2023 May 23.
- Results publication: PubMed 34487587Vincent JL, Creteur J. Appropriate care for the elderly in the ICU. J Intern Med. 2022 Apr;291(4):458-468. doi: 10.1111/joim.13371. Epub 2021 Oct 5.
- Results publication: PubMed 33896003Andersen FH, Ariansen Haaland O, Klepstad P, Flaatten H. Frailty and survival in elderly intensive care patients in Norway. Acta Anaesthesiol Scand. 2021 Sep;65(8):1065-1072. doi: 10.1111/aas.13836. Epub 2021 May 7.
- Results publication: PubMed 30769294Ramos JGR, Ranzani OT, Perondi B, Dias RD, Jones D, Carvalho CRR, Velasco IT, Forte DN. A decision-aid tool for ICU admission triage is associated with a reduction in potentially inappropriate intensive care unit admissions. J Crit Care. 2019 Jun;51:77-83. doi: 10.1016/j.jcrc.2019.02.002. Epub 2019 Feb 4.
- Results publication: PubMed 26934945Kim J, Choi SM, Park YS, Lee CH, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Lee J. Factors influencing the initiation of intensive care in elderly patients and their families: A retrospective cohort study. Palliat Med. 2016 Sep;30(8):789-99. doi: 10.1177/0269216316634241. Epub 2016 Mar 2.
- Results publication: PubMed 30255319Haas LEM, van Beusekom I, van Dijk D, Hamaker ME, Bakhshi-Raiez F, de Lange DW, de Keizer NF. Healthcare-related costs in very elderly intensive care patients. Intensive Care Med. 2018 Nov;44(11):1896-1903. doi: 10.1007/s00134-018-5381-8. Epub 2018 Sep 25.
- Results publication: PubMed 30673049Ferretti-Rebustini REL, Bispo NDS, Alves WDS, Dias TN, Santoro CM, Padilha KG. Level of acuity, severity and intensity of care of adults and older adults admitted to the Intensive Care Unit. Rev Esc Enferm USP. 2019 Jan 21;53:e03416. doi: 10.1590/S1980-220X2017051403416. English, Portuguese.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Norton Perez, MD principal investigator
Hospital Departamental de Villavicencio
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Geriatrics, run by Hospital Departamental de Villavicencio at 1 site in Colombia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 9 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Colombia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Norton Perez, MD (3112517471, norton.perez@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
ICU mortality (time frame: 30 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07001410, which also lists 12 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Feb 2026.