Primary Dysmenorrhea (PD)NCT07000487
Effect of Yoga Training on Nausea and Pain
A study testing Yoga in people with Primary Dysmenorrhea (PD) and Yoga, run by Çankırı Karatekin University at 1 site in Turkey (Türkiye).
Trial summary
This study was planned to determine the effect of yoga training on reducing nausea and pain symptoms in young women with primary dysmenorrhea. As a result of this study, evaluating the extent to which women with dysmenorrhea experience pain and nausea and the extent to which yoga has a positive effect on these… Read more about this study
- Who is it for?
- Ages 18 to 30 years, women only
- Conditions the study is for
- Primary Dysmenorrhea (PD), Yoga
- What is being tested?
- Yoga
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jun 2025to 31 Oct 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Having a regular menstrual cycle
- Being single
- Not having any psychiatric diagnosis or gynecological disease (abnormal uterine bleeding, myoma, ovarian cysts, etc.) extremities and any health problems that may prevent physical exercise
- Not having any systemic disease (heart, diabetes, epilepsy, rheumatoid arthritis, etc.)
- Young women who agree to participate in the study and can speak and understand Turkish
Who cannot join
- Wanting to leave the study, primary dysmenorrhea severity and nausea level below 4 points.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Çankırı
Çankırı, None Selected, 18100
Sakine Yılmaz, Assistant Professor Doctor, +905439380626, sakinee_yilmaz@hotmail.com
Sakine Yılmaz, Assistant Professor Doctor
About this study
Official title: Effect of Yoga Training on Nausea and Pain Symptoms in Young Women With Primary Dysmenorrhea: A Randomized Controlled Trial.
This study was planned to determine the effect of yoga training on reducing nausea and pain symptoms in young women with primary dysmenorrhea. As a result of this study, evaluating the extent to which women with dysmenorrhea experience pain and nausea and the extent to which yoga has a positive effect on these symptoms may shed light on women experiencing these symptoms and developments in the literature, and may increase the use of non-pharmacological approaches. The results of the study will contribute to the literature on dysmenorrhea, one of the important gynecological problems in women. In addition, although there are many results in the literature on the effectiveness of yoga in the management of nausea symptoms with cancer patients, there are not many studies on nausea on dysmenorrhea. In this respect, it will provide important evidence to the literature.
Read the detailed description
Primary dysmenorrhea (PD) is one of the most common gynecological conditions affecting an estimated 67% to 90% of young women and is a painful uterine contraction caused by endometrial laceration . PD is also known as painful periods or menstrual cramps that cause pain during the menstrual cycle. Menstrual pain is the most common symptom associated with primary dysmenorrhea. The pathogenesis of menstrual pain is thought to be due to an abnormal increase in the production of vasoactive prostaglandins in the endometrium, which can induce myometrial hyperactivity, uterine tissue ischemia, and pain. The pain caused by dysmenorrhea begins a few days before menstruation and lasts for 48-72 hours. The pain is usually in the pelvis or lower abdomen and may radiate to the lower back and upper thighs. Other symptoms that the individual may experience include diarrhea, headache, stress, and nausea.
Yoga is one of the self-development and exercise methods that fully trains the soul, mind and body and allows the individual to know themselves. Yoga, which is a mental journey that the individual makes to their inner world, is a technique that allows the person to be alone with themselves as a result of the combination of physical posture, breathing techniques and mental meditation. The yoga-based lifestyle includes positive behavioral changes (yamas and niyamas), physical posture practices (asanas), breathing regulation (pranayama), control of the senses (pratyahara) and meditation techniques (dharana, dhyana and samadhi). It has been determined in the literature that yoga reduces menstrual cramps and distress, and it has been reported that it can be used in menstrual problems due to its safety, lack of side effects, low cost, easy accessibility and noninvasiveness. Previous studies report that yoga suppresses menstrual pain by reducing the level of prostaglandin production and myometrial ischemia through "down-regulation of the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system" and has positive effects on psychological well-being. In addition, studies have determined that yoga is also effective in nausea and vomiting symptoms. In a systematic review conducted on individuals with cancer, it was determined that yoga is effective in symptom management (nausea and vomiting, fatigue, anxiety, depression, etc.). The aim of this study is to determine the effect of yoga training in reducing nausea and pain symptoms in young women with primary dysmenorrhea. The results of the study will contribute to the literature on dysmenorrhea, one of the important gynecological problems in women. In addition, although there are many results in the literature on the effectiveness of yoga in the management of nausea and vomiting symptoms with cancer patients, no study on dysmenorrhea has been found. In this respect, it will also provide important evidence to the literature.
- Conditions
- Primary Dysmenorrhea (PD), Yoga
- Being tested
- Yoga
- Keywords
- primary dysmenorrhea, yoga, pain, nausea, young woman
- Medical subject headings
- Pain, Nausea
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
YogaBehavioural
Hatha yoga will be applied in this study. Yoga practice will be carried out by the researcher for 6 weeks, 1 day face-to-face and 1 day online, and each practice will be 60 minutes, in total 12 sessions, considering the studies done. It will be applied by a researcher with a yoga certificate. Pre-test and post-test nausea and pain measurements will be made.
| Study group | Role | What they receive |
|---|---|---|
| Experimental:Yoga | Experimental | Hatha yoga will be applied in this study. Yoga practice will be carried out by the researcher for 6 weeks, 1 day face-to-face and 1 day online, and each practice will be 60 minutes, in total 12 sessions, considering the studies done. It will be applied by a researcher with a yoga certificate. Pre-test and post-test nausea and pain measurements will be made. Receives: Behavioral: Yoga |
| No Intervention: Control Group | No intervention | No application will be made to this group by the researcher. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analog Scale (VAS)
VAS is a suitable measurement tool for the assessment of acute pain. This scale is used to convert some values that cannot be measured numerically. 0 means "No pain" and 10 means "Worst possible pain".
Measured: Before and 6 weeks after yoga practice
Visual Analog Scale (VAS)
VAS will be used to assess nausea.The scale consists of a horizontal line 100 mm/10 cm long. At the left end of the line is 0 "No nausea", while at the right end is 10 "Severe nausea". The individual is asked to mark the point on the line that will accurately reflect their nausea. The distance of the individual's mark to the left end is measured with a ruler. This distance, measured in millimeters, is accepted as a "score" and recorded. In selecting individuals, values of 5 mm and below on the scale are evaluated as "no nausea", and all values of 5 mm and above are evaluated as "experiencing nausea".
Measured: Before and 6 weeks after yoga practice
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2025
- Study start1 Jun 2025 (estimated)
- Primary completion30 Sep 2025 (estimated)
- Study completion31 Oct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Primary Dysmenorrhea (PD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- The study consists of two groups: control and experimental group.
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 70 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Çankırı Karatekin University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sakine Yılmaz, Çankırı Karatekin University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07000487
- Sponsor's protocol ID
- Primary dysmenorrhea
- Status last verified
- May 2025
- First submitted
- 24 May 2025
- Last updated
- 3 Jun 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Jun 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Yoga Training on Nausea and Pain Symptoms in Young Women With Primary Dysmenorrhea: A Randomized Controlled Trial.
- ClinicalTrials.gov ID
- NCT07000487
- Acronym / sponsor ID
- Primary dysmenorrhea
- Conditions
- Primary Dysmenorrhea (PD), Yoga
- Keywords
- primary dysmenorrhea, yoga, pain, nausea, young woman
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- Çankırı Karatekin UniversityUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 30 Sep 2025 (estimated)
- Study completion
- 31 Oct 2025 (estimated)
- First posted
- 3 Jun 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was planned to determine the effect of yoga training on reducing nausea and pain symptoms in young women with primary dysmenorrhea. As a result of this study, evaluating the extent to which women with dysmenorrhea experience pain and nausea and the extent to which yoga has a positive effect on these symptoms may shed light on women experiencing these symptoms and developments in the literature, and may increase the use of non-pharmacological approaches. The results of the study will contribute to the literature on dysmenorrhea, one of the important gynecological problems in women. In addition, although there are many results in the literature on the effectiveness of yoga in the management of nausea symptoms with cancer patients, there are not many studies on nausea on dysmenorrhea. In this respect, it will provide important evidence to the literature.
Detailed description
Primary dysmenorrhea (PD) is one of the most common gynecological conditions affecting an estimated 67% to 90% of young women and is a painful uterine contraction caused by endometrial laceration . PD is also known as painful periods or menstrual cramps that cause pain during the menstrual cycle. Menstrual pain is the most common symptom associated with primary dysmenorrhea. The pathogenesis of menstrual pain is thought to be due to an abnormal increase in the production of vasoactive prostaglandins in the endometrium, which can induce myometrial hyperactivity, uterine tissue ischemia, and pain. The pain caused by dysmenorrhea begins a few days before menstruation and lasts for 48-72 hours. The pain is usually in the pelvis or lower abdomen and may radiate to the lower back and upper thighs. Other symptoms that the individual may experience include diarrhea, headache, stress, and nausea.
Yoga is one of the self-development and exercise methods that fully trains the soul, mind and body and allows the individual to know themselves. Yoga, which is a mental journey that the individual makes to their inner world, is a technique that allows the person to be alone with themselves as a result of the combination of physical posture, breathing techniques and mental meditation. The yoga-based lifestyle includes positive behavioral changes (yamas and niyamas), physical posture practices (asanas), breathing regulation (pranayama), control of the senses (pratyahara) and meditation techniques (dharana, dhyana and samadhi). It has been determined in the literature that yoga reduces menstrual cramps and distress, and it has been reported that it can be used in menstrual problems due to its safety, lack of side effects, low cost, easy accessibility and noninvasiveness. Previous studies report that yoga suppresses menstrual pain by reducing the level of prostaglandin production and myometrial ischemia through "down-regulation of the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system" and has positive effects on psychological well-being. In addition, studies have determined that yoga is also effective in nausea and vomiting symptoms. In a systematic review conducted on individuals with cancer, it was determined that yoga is effective in symptom management (nausea and vomiting, fatigue, anxiety, depression, etc.). The aim of this study is to determine the effect of yoga training in reducing nausea and pain symptoms in young women with primary dysmenorrhea. The results of the study will contribute to the literature on dysmenorrhea, one of the important gynecological problems in women. In addition, although there are many results in the literature on the effectiveness of yoga in the management of nausea and vomiting symptoms with cancer patients, no study on dysmenorrhea has been found. In this respect, it will also provide important evidence to the literature.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
- Model description
- The study consists of two groups: control and experimental group.
| Arm | Type | Receives |
|---|---|---|
| Experimental:Yoga | Experimental | Behavioral: YogaHatha yoga will be applied in this study. Yoga practice will be carried out by the researcher for 6 weeks, 1 day face-to-face and 1 day online, and each practice will be 60 minutes, in total 12 sessions, considering the studies done. It will be applied by a researcher with a yoga certificate. Pre-test and post-test nausea and pain measurements will be made. |
| No Intervention: Control Group | No intervention | –No application will be made to this group by the researcher. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Having a regular menstrual cycle
- Being single
- Not having any psychiatric diagnosis or gynecological disease (abnormal uterine bleeding, myoma, ovarian cysts, etc.) extremities and any health problems that may prevent physical exercise
- Not having any systemic disease (heart, diabetes, epilepsy, rheumatoid arthritis, etc.)
- Young women who agree to participate in the study and can speak and understand Turkish
Key exclusion criteria (1 listed)
- Wanting to leave the study, primary dysmenorrhea severity and nausea level below 4 points.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| YogaHatha yoga will be applied in this study. Yoga practice will be carried out by the researcher for 6 weeks, 1 day face-to-face and 1 day online, and each practice will be 60 minutes, in total 12 sessions, considering the studies done. It will be applied by a researcher with a yoga certificate. Pre-test and post-test nausea and pain measurements will be made. | Behavioural | Experimental:Yoga |
Primary outcome
Visual Analog Scale (VAS)
Time frame: Before and 6 weeks after yoga practice
VAS is a suitable measurement tool for the assessment of acute pain. This scale is used to convert some values that cannot be measured numerically. 0 means "No pain" and 10 means "Worst possible pain".
Visual Analog Scale (VAS)
Time frame: Before and 6 weeks after yoga practice
VAS will be used to assess nausea.The scale consists of a horizontal line 100 mm/10 cm long. At the left end of the line is 0 "No nausea", while at the right end is 10 "Severe nausea". The individual is asked to mark the point on the line that will accurately reflect their nausea. The distance of the individual's mark to the left end is measured with a ruler. This distance, measured in millimeters, is accepted as a "score" and recorded. In selecting individuals, values of 5 mm and below on the scale are evaluated as "no nausea", and all values of 5 mm and above are evaluated as "experiencing nausea".
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jun 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Yoga in people with Primary Dysmenorrhea (PD) and Yoga, run by Çankırı Karatekin University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Sakine Yılmaz (05439380626, sakinee_yilmaz@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analog Scale (VAS) (time frame: Before and 6 weeks after yoga practice). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jun 2025.