MigraineNCT06991504
The Effect of Cervical Stabilization Training in Individuals With Migraine
A study testing Cervical Stabilization Exercises, vestibular exercises and Classic cervical/ neck exercises in people with Migraine, run by Zonguldak Bulent Ecevit University at 1 site in Turkey (Türkiye).
Trial summary
Studies examining stabilization training and cervical muscle endurance generally focused on headache as the main topic and did not focus on migraine. Studies examining the effects of vestibular training focused on the effects on vestibular migraine and did not address migraine holistically. Read more about this study
- Who is it for?
- Ages 18 years and older, women only
- Conditions the study is for
- Migraine
- What is being tested?
- Cervical Stabilization Exercises, vestibular exercises and Classic cervical/ neck exercises
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 3 Feb 2025to 15 May 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Being over 18 years old
- Being diagnosed with migraine by a neurologist according to the International Headache Society Criteria
- Complaining of headache at least once a week or more in the last year
Who cannot join
- History of other diseases or operations in the cervical region
- Having any neurological or orthopedic disease
- Passing a serious head and/or neck trauma
- Participating in a physiotherapy program for head and neck pain in the last 12 months
- Having a visual impairment
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Zonguldak Bulent Ecevit University
Merkez, Zonguldak Province, 03000
About this study
Official title: The Effect of Cervical Stabilization Training and Vestibular Training on Cervical Region and Balance in Individuals With Migraine
Studies examining stabilization training and cervical muscle endurance generally focused on headache as the main topic and did not focus on migraine. Studies examining the effects of vestibular training focused on the effects on vestibular migraine and did not address migraine holistically. Although the effects of vestibular rehabilitation and cervical stabilisation training on balance, cervical muscle endurance and joint position error in individuals with migraine have been examined separately, no study has been found in which all these topics were combined. Based on these reasons, this study aims to investigate the effects of two trainings on cervical muscle strength, normal range of motion, anterior tilt, joint position error, deep muscle endurance and balance in individuals with migraine.
- Conditions
- Migraine
- Being tested
- Cervical Stabilization Exercises, vestibular exercises, Classic cervical/ neck exercises
- Keywords
- migraine
- Medical subject headings
- Migraine Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cervical Stabilization ExercisesBehavioural
The main goal of this training is to increase the strength and endurance of the deep cervical flexor and extensor muscles.
vestibular exercisesBehavioural
Vestibular exercises are a training used in individuals with migraine to ensure balance and coordination.
Classic cervical/ neck exercisesBehavioural
Classic cervical neck exercises including stretching and strengthening
| Study group | Role | What they receive |
|---|---|---|
| STABILIZATION GROUP | Experimental | Group receiving cervical stabilization exercise Receives: Behavioral: Cervical Stabilization Exercises |
| Vestıbular rehabilitation | Experimental | Group receiving vestibular rehabilitation Receives: Behavioral: vestibular exercises |
| Control Group | Experimental | Group receiving classical neck exercise Receives: Behavioral: Classic cervical/ neck exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
Craniovertebral Angle
Craniovertebral Angle measuremnt
Measured: up to 4 weeks
Tragus- Wall Distance
Tragus- Wall Distance is is used to measure cervical anterior tilt.
Measured: up to 4 weeks
Cervical Range of Motion Measurement (C-ROM)
Cervical Range of Motion Measurement (C-ROM) is used to measure range of motion.
Measured: up to 4 weeks
Craniocervical Flexion Test
Craniocervical Flexion Test measures the endurance of the deep cervical flexor muscles.
Measured: up to 4 weeks
Cervical Joint Position Sensation Assessment
The Cervical Joint Position Sensation Assessment is an easy standardized measurement and provides a sensory assessment.
Measured: up to 4 weeks
Mini Balance Assessment Systems Test
The Mini Balance Assessment Systems Test is an easy-to-administer and reliable balance assessment.
Measured: up to 4 weeks
Secondary outcomes (5)
Visual Analogue Scale - VAS
Visual Analogue Scale - VAS assesses pain.
Measured: up to 4 weeks
Pain Catastrophization Scale
Pain Catastrophization Scale assesses pain.
Measured: up to 4 weeks
Migraine-related disability assessment scale
Migraine-related disability assessment scale is a method applied in migraine patients and evaluates the level of disability.
Measured: up to 4 weeks
Neck Disability Questionnaire
Neck Disability Questionnaire assesses neck disability.
Measured: up to 4 weeks
Beck depression questionnaire
Beck depression questionnaire assesses emotional state
Measured: up to 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 May 2025
- Study start3 Feb 2025
- Primary completion3 May 2025
- Study completion15 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for MigraineStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zonguldak Bulent Ecevit University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, ARZUCAN TOKSAL UÇAR, Zonguldak Bulent Ecevit University
- Investigators
- Arzucan Toksal Uçar, PT. PhD:, Principal investigator, Zonguldak Bulent Ecevit UniversityGizem Alarçin, PT., Principal investigator, Zonguldak Bulent Ecevit UniversityEsra Acıman Demirel, MD, Principal investigator, Zonguldak Bulent Ecevit University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06991504
- Sponsor's protocol ID
- BEUN-MIGREN
- Status last verified
- May 2025
- First submitted
- 12 May 2025
- Last updated
- 28 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Cervical Stabilization Training and Vestibular Training on Cervical Region and Balance in Individuals With Migraine
- ClinicalTrials.gov ID
- NCT06991504
- Acronym / sponsor ID
- BEUN-MIGREN
- Conditions
- Migraine
- Keywords
- migraine
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Zonguldak Bulent Ecevit UniversityUniversity, hospital or other
- Study start
- 3 Feb 2025 (actual)
- Primary completion
- 3 May 2025 (actual)
- Study completion
- 15 May 2025 (actual)
- First posted
- 28 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Studies examining stabilization training and cervical muscle endurance generally focused on headache as the main topic and did not focus on migraine. Studies examining the effects of vestibular training focused on the effects on vestibular migraine and did not address migraine holistically. Although the effects of vestibular rehabilitation and cervical stabilisation training on balance, cervical muscle endurance and joint position error in individuals with migraine have been examined separately, no study has been found in which all these topics were combined. Based on these reasons, this study aims to investigate the effects of two trainings on cervical muscle strength, normal range of motion, anterior tilt, joint position error, deep muscle endurance and balance in individuals with migraine.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| STABILIZATION GROUP | Experimental | Behavioral: Cervical Stabilization ExercisesGroup receiving cervical stabilization exercise |
| Vestıbular rehabilitation | Experimental | Behavioral: vestibular exercisesGroup receiving vestibular rehabilitation |
| Control Group | Experimental | Behavioral: Classic cervical/ neck exercisesGroup receiving classical neck exercise |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Being over 18 years old
- Being diagnosed with migraine by a neurologist according to the International Headache Society Criteria
- Complaining of headache at least once a week or more in the last year
Key exclusion criteria (5 listed)
- History of other diseases or operations in the cervical region
- Having any neurological or orthopedic disease
- Passing a serious head and/or neck trauma
- Participating in a physiotherapy program for head and neck pain in the last 12 months
- Having a visual impairment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cervical Stabilization ExercisesThe main goal of this training is to increase the strength and endurance of the deep cervical flexor and extensor muscles. | Behavioural | STABILIZATION GROUP |
| vestibular exercisesVestibular exercises are a training used in individuals with migraine to ensure balance and coordination. | Behavioural | Vestıbular rehabilitation |
| Classic cervical/ neck exercisesClassic cervical neck exercises including stretching and strengthening | Behavioural | Control Group |
Primary outcome
Craniovertebral Angle
Time frame: up to 4 weeks
Craniovertebral Angle measuremnt
Tragus- Wall Distance
Time frame: up to 4 weeks
Tragus- Wall Distance is is used to measure cervical anterior tilt.
Cervical Range of Motion Measurement (C-ROM)
Time frame: up to 4 weeks
Cervical Range of Motion Measurement (C-ROM) is used to measure range of motion.
Craniocervical Flexion Test
Time frame: up to 4 weeks
Craniocervical Flexion Test measures the endurance of the deep cervical flexor muscles.
Cervical Joint Position Sensation Assessment
Time frame: up to 4 weeks
The Cervical Joint Position Sensation Assessment is an easy standardized measurement and provides a sensory assessment.
Mini Balance Assessment Systems Test
Time frame: up to 4 weeks
The Mini Balance Assessment Systems Test is an easy-to-administer and reliable balance assessment.
5 secondary outcomes
Visual Analogue Scale - VAS
Time frame: up to 4 weeks
Pain Catastrophization Scale
Time frame: up to 4 weeks
Migraine-related disability assessment scale
Time frame: up to 4 weeks
Neck Disability Questionnaire
Time frame: up to 4 weeks
Beck depression questionnaire
Time frame: up to 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2025.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Arzucan Toksal Uçar, PT. PhD: principal investigator
Zonguldak Bulent Ecevit University
Gizem Alarçin, PT. principal investigator
Zonguldak Bulent Ecevit University
Esra Acıman Demirel, MD principal investigator
Zonguldak Bulent Ecevit University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cervical Stabilization Exercises, vestibular exercises and Classic cervical/ neck exercises in people with Migraine, run by Zonguldak Bulent Ecevit University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Craniovertebral Angle (time frame: up to 4 weeks). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2025; AzTrials last refreshed its copy on 7 Nov 2026.