Lateral Patellar Compression SyndromeLL-BFRTNCT06988917
Rehabilitation Efficacy of Low-Load Blood Flow Restriction Training for Lateral Patellar Compression Syndrome
An observational study of Lateral Patellar Compression Syndrome, run by Peking University Third Hospital at 1 site in China.
Trial summary
The purpose of this study is to understand the effect of low-load blood flow restriction training on the rehabilitation effect of patients after lateral patellar compression syndrome surgery, and to observe the differences between low-load blood flow restriction training combined with conventional rehabilitation… Read more about this study
- Who is it for?
- Ages 30 to 60 years
- Conditions the study is for
- Lateral Patellar Compression Syndrome
- What is being tested?
- the regular rehabilitation program and The blood flow limiting pressure band
- Type of treatment
- Medical device, Lifestyle or therapy programme
- How many people
- 60 participants
- Where
- 1 siteChina
- Study dates
- 2 Mar 2024to 1 Aug 2024
- How long will I take part?
- 6 Weeks
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 60 years
- All sexes
- No healthy volunteers
- Adult
Study population: Patient with lateral patellar compression syndrome after lateral retinacular release
Who may be able to join
- Aged 30-60 years with a Visual Analog Scale (VAS) score ≥3;
- Diagnosed with lateral patellar compression syndrome confirmed by MRI and clinical evaluation, having undergone arthroscopic lateral retinacular release surgery;
- Presenting postoperative reduction in thigh circumference on the affected side, accompanied by quadriceps muscle atrophy and decreased muscle strength;
- Minimum postoperative duration of ≥2 weeks, with signed informed consent and demonstrated ability to comply with the study protocol.
Who cannot join
- Patients with concomitant fractures or other ligament injuries (including those with prior ACL reconstruction);
- Individuals presenting with severe osteoarthritis or rheumatoid arthritis;
- Those with medical histories of deep vein thrombosis, coagulation disorders, vascular diseases, or diabetes mellitus;
- Subjects with active infections, malignancies, current pregnancy, or psychiatric disorders.
Trial locations and contacts
1 site in 1 country.
About this study
The purpose of this study is to understand the effect of low-load blood flow restriction training on the rehabilitation effect of patients after lateral patellar compression syndrome surgery, and to observe the differences between low-load blood flow restriction training combined with conventional rehabilitation training and conventional rehabilitation training. The main question it aims to answer is:
Can low-load blood flow restriction training improve the rehabilitation effect of patients after surgery for lateral patellar hypertension syndrome? Researchers compared conventional rehabilitation training with conventional rehabilitation training combined with low-load blood-limiting training to explore the effect of blood-limiting training combined with conventional rehabilitation training on the lower extremity function of patients after lateral patellar compression syndrome surgery, providing experimental and theoretical basis for formulating rehabilitation training programs.
- Conditions
- Lateral Patellar Compression Syndrome
- Being tested
- the regular rehabilitation program, The blood flow limiting pressure band
- Keywords
- Lateral Patellar Compression Syndrome, patellofemoral joint, LL-BFRT
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
the regular rehabilitation programBehavioural
Each training session consists of a 10-minute warm-up (including power cycling, full-body stretching, etc.) At the same time, use the foam axis to relax the lateral oblique femoris and iliotibial band to relieve the pressure on the lateral side of the patella), 40 minutes of formal training (including wall squats with a ball, straight leg raising resistance training, terminal resistance knee extension training, bench kick ball clamping training, and balance training), and 10 minutes of relaxation (using a foam roller, foam axis and other combined techniques to relax the muscles Especially for the lower limb muscles such as the lateral femoris, iliotibial band, and tibialis anterior muscle.
The blood flow limiting pressure bandDevice
The experimental group (LL-BFRT group) wore a flow-limiting pressure band for exercise during routine rehabilitation training. The blood flow limiting pressure band used in this study mainly consists of a 109*10cm leg pressure band, a barometric display dial with a pressure range of 0-300mmHg, and a pressure pump. In the experiment, we fixed the blood flow restriction pressure band in the area for measuring the circumference and adjusted the blood flow restriction pressure according to the thigh circumference of the subjects to maintain it within the range of 40%-60% arterial occlusion pressure. The way to limit blood flow is intermittent inflation, that is, during the intervals of muscle strength training, the cuff deflation operation is carried out simultaneously.
| Study group | Role | What they receive |
|---|---|---|
| The experimental group (LL-BFRT group) | The experimental group (LL-BFRT group) received exercise intervention treatment for 4 weeks, training three times a week, each time lasting for 1 hour. Compared with the control group (conventional rehabilitation group), the movements and intensities of the two groups remained consistent during the exercise intervention. Only the experimental group wore a flow-limiting pressure band for exercise during the intervention. The blood flow limiting pressure band used in this study mainly consists of a 109*10cm leg pressure band, a barometric display dial with a pressure range of 0-300mmHg, and a pressure pump. In the experiment, we fixed the blood flow restriction pressure band in the area for measuring the circumference and adjusted the blood flow restriction pressure according to the thigh circumference of the subjects to maintain it within the range of 40%-60% arterial occlusion pressure. The way to limit blood flow is intermittent inflation. Receives: Behavioral: the regular rehabilitation program; Device: The blood flow limiting pressure band | |
| The control group (conventional rehabilitation group) | The control group (conventional rehabilitation group) received exercise intervention treatment for 4 weeks, with training three times a week, each lasting for 1 hour. The specific intervention contents are: Each training session consists of a 10-minute warm-up (including power cycling, full-body stretching, etc.) At the same time, use the foam axis to relax the lateral oblique femoris and iliotibial band to relieve the pressure on the lateral side of the patella), 40 minutes of formal training (including wall squats with a ball, straight leg raising resistance training, terminal resistance knee extension training, bench kick ball clamping training, and balance training), and 10 minutes of relaxation (using a foam roller, foam axis and other combined techniques to relax the muscles Especially for the lower limb muscles such as the lateral femoris, iliotibial band, and tibialis anterior muscle. Receives: Behavioral: the regular rehabilitation program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Lysholm score
Measured: 0-4week
VAS score
Measured: 0-4week
Peak torque of knee extension
Measured: 0-4week
Quadriceps thickness
Measured: 0-4week
Secondary outcomes (2)
Thigh circumference
Measured: 0-4week
Range of motion of the knee joint
Measured: 0-4week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 May 2025
- Study start2 Mar 2024
- Primary completion1 Aug 2024
- Study completion1 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lateral Patellar Compression SyndromeStudies of the same condition, open and under way.
- More trials run by Peking University Third HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 60 participants (actual)
- Target duration
- 6 Weeks
Sponsor and investigators
- Lead sponsor
- Peking University Third Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Yuping Yang, Principal investigator
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06988917
- Sponsor's protocol ID
- M2024150
- Acronym
- LL-BFRT
- Status last verified
- Mar 2024
- First submitted
- 29 Apr 2025
- Last updated
- 25 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Rehabilitation Efficacy of Low-Load Blood Flow Restriction Training for Lateral Patellar Compression Syndrome
- ClinicalTrials.gov ID
- NCT06988917
- Acronym / sponsor ID
- LL-BFRT / M2024150
- Conditions
- Lateral Patellar Compression Syndrome
- Keywords
- Lateral Patellar Compression Syndrome, patellofemoral joint, LL-BFRT
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Peking University Third HospitalUniversity, hospital or other
- Study start
- 2 Mar 2024 (actual)
- Primary completion
- 1 Aug 2024 (actual)
- Study completion
- 1 Aug 2024 (actual)
- First posted
- 25 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to understand the effect of low-load blood flow restriction training on the rehabilitation effect of patients after lateral patellar compression syndrome surgery, and to observe the differences between low-load blood flow restriction training combined with conventional rehabilitation training and conventional rehabilitation training. The main question it aims to answer is:
Can low-load blood flow restriction training improve the rehabilitation effect of patients after surgery for lateral patellar hypertension syndrome? Researchers compared conventional rehabilitation training with conventional rehabilitation training combined with low-load blood-limiting training to explore the effect of blood-limiting training combined with conventional rehabilitation training on the lower extremity function of patients after lateral patellar compression syndrome surgery, providing experimental and theoretical basis for formulating rehabilitation training programs.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Target follow-up
- 6 Weeks
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| The experimental group (LL-BFRT group) | – | Behavioral: the regular rehabilitation program, Device: The blood flow limiting pressure bandThe experimental group (LL-BFRT group) received exercise intervention treatment for 4 weeks, training three times a week, each time lasting for 1 hour. Compared with the control group (conventional rehabilitation group), the movements and intensities of the two groups remained consistent during the exercise intervention. Only the experimental group wore a flow-limiting pressure band for exercise during the intervention. The blood flow limiting pressure band used in this study mainly consists of a 109*10cm leg pressure band, a barometric display dial with a pressure range of 0-300mmHg, and a pressure pump. In the experiment, we fixed the blood flow restriction pressure band in the area for measuring the circumference and adjusted the blood flow restriction pressure according to the thigh circumference of the subjects to maintain it within the range of 40%-60% arterial occlusion pressure. The way to limit blood flow is intermittent inflation. |
| The control group (conventional rehabilitation group) | – | Behavioral: the regular rehabilitation programThe control group (conventional rehabilitation group) received exercise intervention treatment for 4 weeks, with training three times a week, each lasting for 1 hour. The specific intervention contents are: Each training session consists of a 10-minute warm-up (including power cycling, full-body stretching, etc.) At the same time, use the foam axis to relax the lateral oblique femoris and iliotibial band to relieve the pressure on the lateral side of the patella), 40 minutes of formal training (including wall squats with a ball, straight leg raising resistance training, terminal resistance knee extension training, bench kick ball clamping training, and balance training), and 10 minutes of relaxation (using a foam roller, foam axis and other combined techniques to relax the muscles Especially for the lower limb muscles such as the lateral femoris, iliotibial band, and tibialis anterior muscle. |
Who may qualify
- Ages
- 30 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Patient with lateral patellar compression syndrome after lateral retinacular release
Key inclusion criteria (4 listed)
- Aged 30-60 years with a Visual Analog Scale (VAS) score ≥3;
- Diagnosed with lateral patellar compression syndrome confirmed by MRI and clinical evaluation, having undergone arthroscopic lateral retinacular release surgery;
- Presenting postoperative reduction in thigh circumference on the affected side, accompanied by quadriceps muscle atrophy and decreased muscle strength;
- Minimum postoperative duration of ≥2 weeks, with signed informed consent and demonstrated ability to comply with the study protocol.
Key exclusion criteria (4 listed)
- Patients with concomitant fractures or other ligament injuries (including those with prior ACL reconstruction);
- Individuals presenting with severe osteoarthritis or rheumatoid arthritis;
- Those with medical histories of deep vein thrombosis, coagulation disorders, vascular diseases, or diabetes mellitus;
- Subjects with active infections, malignancies, current pregnancy, or psychiatric disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| the regular rehabilitation programEach training session consists of a 10-minute warm-up (including power cycling, full-body stretching, etc.) At the same time, use the foam axis to relax the lateral oblique femoris and iliotibial band to relieve the pressure on the lateral side of the patella), 40 minutes of formal training (including wall squats with a ball, straight leg raising resistance training, terminal resistance knee extension training, bench kick ball clamping training, and balance training), and 10 minutes of relaxation (using a foam roller, foam axis and other combined techniques to relax the muscles Especially for the lower limb muscles such as the lateral femoris, iliotibial band, and tibialis anterior muscle. | Behavioural | The control group (conventional rehabilitation group), The experimental group (LL-BFRT group) |
| The blood flow limiting pressure bandThe experimental group (LL-BFRT group) wore a flow-limiting pressure band for exercise during routine rehabilitation training. The blood flow limiting pressure band used in this study mainly consists of a 109*10cm leg pressure band, a barometric display dial with a pressure range of 0-300mmHg, and a pressure pump. In the experiment, we fixed the blood flow restriction pressure band in the area for measuring the circumference and adjusted the blood flow restriction pressure according to the thigh circumference of the subjects to maintain it within the range of 40%-60% arterial occlusion pressure. The way to limit blood flow is intermittent inflation, that is, during the intervals of muscle strength training, the cuff deflation operation is carried out simultaneously. | Device | The experimental group (LL-BFRT group) |
Primary outcome
Lysholm score
Time frame: 0-4week
VAS score
Time frame: 0-4week
Peak torque of knee extension
Time frame: 0-4week
Quadriceps thickness
Time frame: 0-4week
2 secondary outcomes
Thigh circumference
Time frame: 0-4week
Range of motion of the knee joint
Time frame: 0-4week
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 May 2025.
Related trials for Lateral Patellar Compression Syndrome
Enrolling by invitation
To Compare the Clinical Efficacy of Arthroscopic Lateral Retinacular Release and Exercise Therapy in the Treatment of Lateral Patellar Crush Syndrome
Lateral Patellar Syndrome
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Yuping Yang principal investigator
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Lateral Patellar Compression Syndrome, run by Peking University Third Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Lysholm score (time frame: 0-4week). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 May 2025.