Pediatric OverweightHealthy LIFTNCT06969235
Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment
A study testing intensive health behavior and lifestyle treatment in people with Pediatric Overweight, run by University of Missouri-Columbia at 1 site in United States.
Trial summary
The objectives of this open trial feasibility study are to examine the impacts of intensive health behavior and lifestyle treatment (IHBLT) on youth and caregiver executive functioning (EF), weight status, health behaviors (dietary intake, disordered eating, physical activity), and psychological functioning. Read more about this study
- Who is it for?
- Ages 13 to 17 years
- Conditions the study is for
- Pediatric Overweight
- What is being tested?
- intensive health behavior and lifestyle treatment
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteUnited States
- Study dates
- 5 May 2025to Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 17 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- Youth 13-17 years old
- Youth with OV/OB (BMI≥85th percentile for age/gender norms)
- Participating caregiver must be the participating youth's legal guardian
- Participating youth and caregiver speak and read English
- Participating youth and caregiver agree to attend IHBLT group meetings in-between the pre- and post-treatment assessments.
Who cannot join
- Youth pervasive developmental disorder (e.g., intellectual disability)
- Youth or caregiver in commercial weight loss program or taking prescribed medications for the prior three months that impact appetite or weight
- Youth or caregiver with documented history of eating disorder or untreated severe depression
- Both youth and caregiver scores are two standard deviations or above the mean on the CPT-3 Commissions and Stroop Interference, representing significantly higher than average EF skills.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
College of Health Sciences, University of Missouri
Columbia, Missouri, 65211
Crystal Lim, PhD, ABPP, 573-882-2667, limcs@health.missouri.edu
About this study
Official title: Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment to Address Pediatric Obesity (Healthy LIFT Groups)
The objectives of this open trial feasibility study are to examine the impacts of intensive health behavior and lifestyle treatment (IHBLT) on youth and caregiver executive functioning (EF), weight status, health behaviors (dietary intake, disordered eating, physical activity), and psychological functioning. Investigators propose to enroll 10 youth 13 to 17 years of age who have overweight or obesity (OV/OB) and a primary caregiver. Families will receive six months of evidence-based family focused group IHBLT based on social, cognitive, and family systems theories. Families will complete assessments of EF skills (objective and self-report), weight status, dietary intake, physical activity, and psychological functioning at pre- and post-treatment.
- Conditions
- Pediatric Overweight
- Being tested
- intensive health behavior and lifestyle treatment
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
intensive health behavior and lifestyle treatmentBehavioural
the IHLBT will consist of 18 group meetings over 6 months that teens and parents attend. Topics covered during the meetings will include discussions regarding nutrition and physical activity recommendations, family communication, and use of strategies like monitoring, planning, goal setting, and problem solving.
| Study group | Role | What they receive |
|---|---|---|
| IHLBT | Experimental | intensive health behavior and lifestlye treatment Receives: Behavioral: intensive health behavior and lifestyle treatment |
What is being measured
The primary outcome is the main question the study is designed to answer.
Youth EF - CPT-3 Commissions
Youth T-score on the Continuous Performance Test Third Edition (CPT-3) Commissions subscale; T-scores (M = 50, SD = 10) used with higher scores representing worse executive functioning (EF)
Measured: Post-Treatment (Month 6)
Youth EF - Stroop
Youth T-score on the Stroop Color Word Interference scale; T-scores (Mean = 50, SD = 10) used, with higher scores indicating better executive functioning (EF)
Measured: Post-Treatment (Month 6)
Youth EF - Trails B
Youth Trails B z-score; z-score (Mean = 0, SD = 1), with lower scores indicating worse executive functioning (EF)
Measured: Post-Treatment (Month 6)
Youth EF - BRIEF-2 Self Report GEC
Youth self-report on the Behavior Rating Inventory of Executive Function Second Edition (BRIEF-2) Global Executive Composite (GEC) subscale T-score; T-score (Mean = 50, SD = 10), with higher scores representing worse executive functioning (EF)
Measured: Post-Treatment (Month 6)
Youth EF - BRIEF-2 Parent Report GEC
Parent-report of youth Global Executive Composite (GEC) subscale T-score on the Behavior Rating Inventory of Executive Function Second Edition (BRIEF-2); T-score (Mean = 50, SD = 10), with higher scores representing worse executive functioning (EF)
Measured: Post-Treatment (Month 6)
Secondary outcomes (3)
Youth Weight Status
Youth body mass index (BMI) BMI z-score calculated based on height and weight measurements; z-scores have Mean = 0 and SD = 1; higher scores indicate higher weight status
Measured: Post-Treatment (Month 6)
Youth Dietary Intake
Youth Total kcals from 24 hour dietary recall
Measured: Post-Treatment (Month 6)
Youth Physical Activity
Youth time spent in moderate/vigorous physical activity on BLOCK screener
Measured: Post-Treatment (Month 6)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 May 2025
- Study start5 May 2025
- Primary completionDec 2026 (estimated)
- Study completionAug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pediatric OverweightStudies of the same condition, open and under way.
- More trials run by University of Missouri-ColumbiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 10 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Missouri-Columbia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Crystal Lim, University of Missouri-Columbia
- Investigators
- Crystal Lim, PhD, ABPP, Principal investigator, University of Missouri-Columbia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06969235
- Sponsor's protocol ID
- 2122709
- Acronym
- Healthy LIFT
- Status last verified
- Feb 2026
- First submitted
- 30 Apr 2025
- Last updated
- 12 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment to Address Pediatric Obesity (Healthy LIFT Groups)
- ClinicalTrials.gov ID
- NCT06969235
- Acronym / sponsor ID
- Healthy LIFT / 2122709
- Conditions
- Pediatric Overweight
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 10 participants (estimated)
- Lead sponsor
- University of Missouri-ColumbiaUniversity, hospital or other
- Study start
- 5 May 2025 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Aug 2027 (estimated)
- First posted
- 13 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objectives of this open trial feasibility study are to examine the impacts of intensive health behavior and lifestyle treatment (IHBLT) on youth and caregiver executive functioning (EF), weight status, health behaviors (dietary intake, disordered eating, physical activity), and psychological functioning. Investigators propose to enroll 10 youth 13 to 17 years of age who have overweight or obesity (OV/OB) and a primary caregiver. Families will receive six months of evidence-based family focused group IHBLT based on social, cognitive, and family systems theories. Families will complete assessments of EF skills (objective and self-report), weight status, dietary intake, physical activity, and psychological functioning at pre- and post-treatment.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| IHLBT | Experimental | Behavioral: intensive health behavior and lifestyle treatmentintensive health behavior and lifestlye treatment |
Who may qualify
- Ages
- 13 to 17 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (5 listed)
- Youth 13-17 years old
- Youth with OV/OB (BMI≥85th percentile for age/gender norms)
- Participating caregiver must be the participating youth's legal guardian
- Participating youth and caregiver speak and read English
- Participating youth and caregiver agree to attend IHBLT group meetings in-between the pre- and post-treatment assessments.
Key exclusion criteria (4 listed)
- Youth pervasive developmental disorder (e.g., intellectual disability)
- Youth or caregiver in commercial weight loss program or taking prescribed medications for the prior three months that impact appetite or weight
- Youth or caregiver with documented history of eating disorder or untreated severe depression
- Both youth and caregiver scores are two standard deviations or above the mean on the CPT-3 Commissions and Stroop Interference, representing significantly higher than average EF skills.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| intensive health behavior and lifestyle treatmentthe IHLBT will consist of 18 group meetings over 6 months that teens and parents attend. Topics covered during the meetings will include discussions regarding nutrition and physical activity recommendations, family communication, and use of strategies like monitoring, planning, goal setting, and problem solving. | Behavioural | IHLBT |
Primary outcome
Youth EF - CPT-3 Commissions
Time frame: Post-Treatment (Month 6)
Youth T-score on the Continuous Performance Test Third Edition (CPT-3) Commissions subscale; T-scores (M = 50, SD = 10) used with higher scores representing worse executive functioning (EF)
Youth EF - Stroop
Time frame: Post-Treatment (Month 6)
Youth T-score on the Stroop Color Word Interference scale; T-scores (Mean = 50, SD = 10) used, with higher scores indicating better executive functioning (EF)
Youth EF - Trails B
Time frame: Post-Treatment (Month 6)
Youth Trails B z-score; z-score (Mean = 0, SD = 1), with lower scores indicating worse executive functioning (EF)
Youth EF - BRIEF-2 Self Report GEC
Time frame: Post-Treatment (Month 6)
Youth self-report on the Behavior Rating Inventory of Executive Function Second Edition (BRIEF-2) Global Executive Composite (GEC) subscale T-score; T-score (Mean = 50, SD = 10), with higher scores representing worse executive functioning (EF)
Youth EF - BRIEF-2 Parent Report GEC
Time frame: Post-Treatment (Month 6)
Parent-report of youth Global Executive Composite (GEC) subscale T-score on the Behavior Rating Inventory of Executive Function Second Edition (BRIEF-2); T-score (Mean = 50, SD = 10), with higher scores representing worse executive functioning (EF)
3 secondary outcomes
Youth Weight Status
Time frame: Post-Treatment (Month 6)
Youth Dietary Intake
Time frame: Post-Treatment (Month 6)
Youth Physical Activity
Time frame: Post-Treatment (Month 6)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
College of Health Sciences, University of Missouri
Columbia, United States
Crystal Lim, PhD, ABPP principal investigator
University of Missouri-Columbia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing intensive health behavior and lifestyle treatment in people with Pediatric Overweight, run by University of Missouri-Columbia at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 12 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Youth EF - CPT-3 Commissions (time frame: Post-Treatment (Month 6)). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Feb 2026.