Dysfunctional BreathingDISFITNCT06943027
Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healty Adults
An observational study of Dysfunctional Breathing, run by Elif Tunç.
Trial summary
This observational study aims to investigate the relationship between dysfunctional breathing and physical fitness parameters in healthy adults aged 18-35. Participants will be evaluated using the Nijmegen Questionnaire to assess dysfunctional breathing symptoms, and their physical fitness will be measured using the… Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Dysfunctional Breathing
- How many people
- 38 participants
- Where
- No sites listed yet
- Study dates
- 15 May 2025to 15 Jul 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: The study population will consist of healthy adults aged 18-35 years with no known systemic, neurological, or musculoskeletal conditions. Participants will be screened using the Nijmegen Questionnaire to identify symptoms of dysfunctional breathing.
Who may be able to join
- Aged between 18-35 years
- Healthy individuals with no known systemic, neurological, or musculoskeletal disorders
- Nijmegen Questionnaire score >23 (indicative of dysfunctional breathing)
- Voluntary participation with informed consent
Who cannot join
- Diagnosed with respiratory, cardiovascular, or metabolic disease
- Currently receiving physiotherapy or pulmonary rehabilitation
- Regular use of medication affecting breathing or exercise capacity
- Pregnancy
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healthy Adults
This observational study aims to investigate the relationship between dysfunctional breathing and physical fitness parameters in healthy adults aged 18-35. Participants will be evaluated using the Nijmegen Questionnaire to assess dysfunctional breathing symptoms, and their physical fitness will be measured using the ALPHA-FIT Test Battery. Respiratory muscle strength and pulmonary function will also be assessed. The findings may help healthcare professionals better understand dysfunctional breathing and develop targeted treatment programs.
Read the detailed description
Dysfunctional breathing (DB) is characterized by chronic alterations in the respiratory cycle, often leading to symptoms such as dyspnea, chest tightness, and hyperventilation. Despite its prevalence, DB is frequently underdiagnosed and mismanaged due to limited awareness among healthcare professionals. This cross-sectional study aims to evaluate the relationship between DB symptoms and physical fitness in healthy young adults. A total of 38 participants diagnosed with DB will be assessed at Istinye University using the Nijmegen Questionnaire, ALPHA-FIT Test Battery, spirometry, and measurements of maximum inspiratory (MIP) and expiratory (MEP) mouth pressures. Data on sociodemographic characteristics will also be collected. The results of this study are expected to support clinicians in the accurate identification of DB and provide insight for the development of personalized rehabilitation strategies that improve physical fitness and respiratory health.
- Conditions
- Dysfunctional Breathing
- Keywords
- ALPHA-FIT, Physical Fitness, Respiratory Function, MIP, MEP, Hyperventilation, Young Adults
- Medical subject headings
- Respiratory Aspiration, Hyperventilation
What is being measured
The primary outcome is the main question the study is designed to answer.
Nijmegen Questionnaire Score
Assessment of dysfunctional breathing symptoms using the Nijmegen Questionnaire.
Measured: Baseline
Secondary outcomes (2)
ALPHA-FIT Test Battery Performance
Evaluation of physical fitness components such as strength, flexibility, balance, and endurance in participants.
Measured: Baseline
Maximum Inspiratory Pressure (MIP) and Maximum Expiratory Pressure (MEP)
Measurement of respiratory muscle strength using a mouth pressure device to evaluate inspiratory and expiratory capacities.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Apr 2025
- Study start15 May 2025 (estimated)
- Primary completion15 Jun 2025 (estimated)
- Study completion15 Jul 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Dysfunctional BreathingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 38 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Elif Tunç
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Elif Tunç, Istinye University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06943027
- Sponsor's protocol ID
- ISTU-DS-2025-ET
- Other IDs
- 2209-A
- Acronym
- DISFIT
- Status last verified
- Apr 2025
- First submitted
- 17 Apr 2025
- Last updated
- 24 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Kiesel K, Plisky PJ, Voight ML. Can Serious Injury in Professional Football be Predicted by a Preseason Functional Movement Screen? N Am J Sports Phys Ther. 2007 Aug;2(3):147-58.
PubMed 21522210Courtney R. The functions of breathing and its dysfunctions and their relationship to breathing therapy. Int J Osteopath Med. 2009;12(3):78-85. doi:10.1016/j.ijosm.2009.04.002
Study at a glance
From the registry record, last updated by the sponsor on 24 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Dysfunctional Breathing and Physical Fitness Parameters in Healthy Adults
- ClinicalTrials.gov ID
- NCT06943027
- Acronym / sponsor ID
- DISFIT / ISTU-DS-2025-ET
- Conditions
- Dysfunctional Breathing
- Keywords
- ALPHA-FIT, Physical Fitness, Respiratory Function, MIP, MEP, Hyperventilation, Young Adults
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 38 participants (estimated)
- Lead sponsor
- Elif TunçUniversity, hospital or other
- Study start
- 15 May 2025 (estimated)
- Primary completion
- 15 Jun 2025 (estimated)
- Study completion
- 15 Jul 2025 (estimated)
- First posted
- 24 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to investigate the relationship between dysfunctional breathing and physical fitness parameters in healthy adults aged 18-35. Participants will be evaluated using the Nijmegen Questionnaire to assess dysfunctional breathing symptoms, and their physical fitness will be measured using the ALPHA-FIT Test Battery. Respiratory muscle strength and pulmonary function will also be assessed. The findings may help healthcare professionals better understand dysfunctional breathing and develop targeted treatment programs.
Detailed description
Dysfunctional breathing (DB) is characterized by chronic alterations in the respiratory cycle, often leading to symptoms such as dyspnea, chest tightness, and hyperventilation. Despite its prevalence, DB is frequently underdiagnosed and mismanaged due to limited awareness among healthcare professionals. This cross-sectional study aims to evaluate the relationship between DB symptoms and physical fitness in healthy young adults. A total of 38 participants diagnosed with DB will be assessed at Istinye University using the Nijmegen Questionnaire, ALPHA-FIT Test Battery, spirometry, and measurements of maximum inspiratory (MIP) and expiratory (MEP) mouth pressures. Data on sociodemographic characteristics will also be collected. The results of this study are expected to support clinicians in the accurate identification of DB and provide insight for the development of personalized rehabilitation strategies that improve physical fitness and respiratory health.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- The study population will consist of healthy adults aged 18-35 years with no known systemic, neurological, or musculoskeletal conditions. Participants will be screened using the Nijmegen Questionnaire to identify symptoms of dysfunctional breathing.
Key inclusion criteria (4 listed)
- Aged between 18-35 years
- Healthy individuals with no known systemic, neurological, or musculoskeletal disorders
- Nijmegen Questionnaire score >23 (indicative of dysfunctional breathing)
- Voluntary participation with informed consent
Key exclusion criteria (4 listed)
- Diagnosed with respiratory, cardiovascular, or metabolic disease
- Currently receiving physiotherapy or pulmonary rehabilitation
- Regular use of medication affecting breathing or exercise capacity
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Nijmegen Questionnaire Score
Time frame: Baseline
Assessment of dysfunctional breathing symptoms using the Nijmegen Questionnaire.
2 secondary outcomes
ALPHA-FIT Test Battery Performance
Time frame: Baseline
Maximum Inspiratory Pressure (MIP) and Maximum Expiratory Pressure (MEP)
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Apr 2025.
- Results publication: PubMed 21522210Kiesel K, Plisky PJ, Voight ML. Can Serious Injury in Professional Football be Predicted by a Preseason Functional Movement Screen? N Am J Sports Phys Ther. 2007 Aug;2(3):147-58.
- Results publicationCourtney R. The functions of breathing and its dysfunctions and their relationship to breathing therapy. Int J Osteopath Med. 2009;12(3):78-85. doi:10.1016/j.ijosm.2009.04.002
- Review article on dysfunctional breathing and its assessment in physiotherapy.Link provided by the sponsor.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Dysfunctional Breathing, run by Elif Tunç.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 24 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Elif Tunç, MSc, PhD(c) (+90 535 076 31 39, fzteliftunc@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Nijmegen Questionnaire Score (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06943027, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Apr 2025.