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VisionNCT06934213

Experiment 3: Mixed vs Blocked; Dashboard Paradigm

A study testing Choice and Mixed trials in people with Vision and Healthy, run by Brigham and Women's Hospital at 1 site in United States.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tasks are intermixed. Four search tasks are tested. The target is the same in every task but the types of distractors change from task to task. Read more about this study

Who is it for?
Ages 18 years and olderHealthy volunteers can take part
Conditions the study is for
Vision, Healthy, Attention
What is being tested?
Choice and Mixed trials
Could I receive a placebo?
No, everyone receives an active treatment
How many people
50 participants
Where
1 siteUnited States
Study dates
1 Jun 2024to 30 Jun 2029
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Pass Ishihara color vision test

Who cannot join

  • vision less than 20/25 with correction
  • history of neuromuscular or visual disorders

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Jeremy M Wolfe, PHD contact

6178511166

jwolfe@bwh.harvard.edu

Cailey Tennyson, PhD contact

617-525-3681

ctennyson1@bwh.harvard.edu

United States1 site, 1 recruiting
  • Brigham & Women's Hospital

    Boston, Massachusetts, 02115

    Jeremy M Wolfe, PhD, 617-851-1166, jwolfe@bwh.harvard.edu

    Cailey Tennyson, PhD, 617-525-3681, ctennyson1@bwh.harvard.edu

    Recruiting

Other trials in United States

About this study

Official title: Prevalence Effects in Visual Search: Theoretical and Practical Implications (J)

The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tasks are intermixed. Four search tasks are tested. The target is the same in every task but the types of distractors change from task to task. In this version, observers get some degree of choice in what they are searching.

Read the detailed description

NOTE: This registration is linked to a Human Subjects registration in ASSIST. That, in turn, is part of an NCI Grant, R01EY017001. The grant describes many proposed experiments and notes that many others might be done as follow-up studies. At the suggestion of the NIH, the investigators grouped these studies into several "studies", each covering multiple experiments. The experiment described here is part of Aim 1 of R01EY017001. It is not possible to register a set of experiments through the PRS system in CT.gov and it is not possible to file an annual report for the grant (RPPR) without an NCT number for projects that have started collecting participants. Accordingly, the investigators are describing one experiment here that would be part of the "Project 3" bundle of studies.

When scientists study visual search in the lab, they usually ask people to do dozens of instances of the same type of task in a block. (e.g., Please find a vertical line….in the next 100 trials). However, in many (maybe most) visual searches in the real world, People are rarely looking for the same item (or same type of item) back-to-back. They do one search. Then they do another, and so on. (Find the jam. Now, find the bread. Now find a knife, etc). The investigators want to know if people would produce the same results if investigators mixed different searches together as they do when they test in long blocks of one specific type of search. This is important because the investigators want to know if the rules, established by years of blocked experiments, continue to apply in the more mixed real world.

In some conditions of this version of the mixed/blocked paradigm, observers get to choose the task for the current trial. There are five conditions, each run on a different group of observers.

  1. Trial Choice condition: In this condition, participants are allowed to choose which task to perform on each trial. At the beginning of each trial, the message "Choose your task" appears in the center of the screen. Participants choose one of four tasks by clicking on the corresponding button on the left side of the patch. The button is deactivated when the number of trials completed in a task reached 50. If a deactivated button is clicked, the message "Choose another task" appears at the center again.
  2. Block Choice condition: In this condition, participants begin by choosing one of the four tasks. Participants do not need to choose a task before each trial; the current trial is drawn automatically from the most recently chosen task until the participant actively chooses to switch tasks or until the full complement of trials for that task is exhausted. At the start of each trial, a "switch" button appears at the center of the display for 700 msec. If participants click on that button within the 700 msec, they are prompted to select the task. If participants does not click the switch button within the 700 msec window, the button vanished and a trial from the current task will be presented. When the number of trials of one task reaches its limit, participants are asked to select another task.
  3. Random condition: In this condition, participants do not choose which task to perform on each trial. The order of the trials is randomized and assigned to the participant before each trial. Before each trial, the target task is highlighted and activated, while the other buttons remain deactivated. The trial begins only when the participant clicks on the correct task button.
  4. Blocked condition: In this condition, participants also have no choice. Here, trials of each task type are presented in a blocked fashion. After 50 trials of one type, the task is changed to another task. To keep the motor demands similar to the choice conditions, at the beginning of each trial, participants need to click the highlighted button for the assigned task type. The order of blocks is counterbalanced across participants.
  5. Yoked condition: Participants in this condition see trials in the order chosen by a participant in the Trial Choice condition. Again, to keep the motor demands similar to the choice conditions, at the beginning of each trial, participants need to click the highlighted task button for the assigned task type though they have no choice in the matter.

In all conditions, stimuli are placed in random locations in a jiggled 5 x 5 grid. The grid are placed within a square field that is 0.5 of the maximum height of the screen. Each stimulus item fit into an invisible box that is 0.11 of the screen height. If the viewing distance is about 60 cm, a standard computer screen would show a stimulus field of about 15 deg on a side and each item would be placed in a box of about 3 x 3 deg. The background is white. Trials are divided evenly between three set sizes: 8, 16, and 24 items and evenly between target-present and absent trials. Stimuli are presented until the observer responds by pressing either 'p' or 'q' to indicate target present or absent, respectively. Accuracy feedback is provided after each trial.

Being tested
Choice, Mixed trials
Keywords
visual search, visual attention

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • ChoiceBehavioural

    The observer gets to make a choice about the sequence of trials they see

  • Mixed trialsBehavioural

    The search tasks are either intermixed. Otherwise trials are run in blocks

Study groups in NCT06934213
Study groupRoleWhat they receive
Trial Choice conditionExperimentalIn this condition, participants are allowed to choose which task to perform on each trial. At the beginning of each trial, the message "Choose your task" appears in the center of the screen. Participants choose one of four tasks by clicking on the corresponding button on the left side of the patch. The button is deactivated when the number of trials completed in a task reached 50. If a deactivated button is clicked, the message "Choose another task" appears at the center again.
Receives: Behavioral: Choice; Behavioral: Mixed trials
Block Choice conditionExperimentalIn this condition, participants begin by choosing one of the four tasks. Participants do not need to choose a task before each trial; the current trial is drawn automatically from the most recently chosen task until the participant actively chooses to switch tasks or until the full complement of trials for that task is exhausted. At the start of each trial, a "switch" button appears at the center of the display for 700 msec. If participants click on that button within the 700 msec, they are prompted to select the task. If participants does not click the switch button within the 700 msec window, the button vanished and a trial from the current task will be presented. When the number of trials of one task reaches its limit, participants are asked to select another task.
Receives: Behavioral: Choice; Behavioral: Mixed trials
Random conditionExperimentalIn this condition, participants do not choose which task to perform on each trial. The order of the trials is randomized and assigned to the participant before each trial. Before each trial, the target task is highlighted and activated, while the other buttons remain deactivated. The trial begins only when the participant clicks on the correct task button.
Receives: Behavioral: Choice; Behavioral: Mixed trials
Blocked conditionExperimentalIn this condition, participants also have no choice. Here, trials of each task type are presented in a blocked fashion. After 50 trials of one type, the task is changed to another task. To keep the motor demands similar to the choice conditions, at the beginning of each trial, participants need to click the highlighted button for the assigned task type. The order of blocks is counterbalanced across participants.
Receives: Behavioral: Choice; Behavioral: Mixed trials
Yoked conditionExperimentalParticipants in this condition see trials in the order chosen by a participant in the Trial Choice condition. Again, to keep the motor demands similar to the choice conditions, at the beginning of each trial, participants need to click the highlighted task button for the assigned task type though they have no choice in the matter.
Receives: Behavioral: Choice; Behavioral: Mixed trials

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Response Time (RT)

    How long it takes to respond that the target is present or absent.

    Measured: through study completion, an average of one year

Secondary outcomes (1)
  1. Accuracy

    The rates of false positive and false negative errors

    Measured: through study completion, an average of one year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted18 Apr 2025
  2. Study start1 Jun 2024
  3. Primary completion1 Jun 2029 (estimated)
  4. Study completion30 Jun 2029 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Basic science
Allocation
Randomised
Intervention model
Parallel groups
Model description
There are five conditions. Each condition is a different group of observers.
Masking
None (open label)
Enrolment
50 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06934213
Sponsor's protocol ID
2007P000646-J
Status last verified
Aug 2026
First submitted
11 Apr 2025
Last updated
19 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: We will share de-identified information about age, sex, and individual data

Questions about this trial

What is this clinical trial studying?

A study testing Choice and Mixed trials in people with Vision and Healthy, run by Brigham and Women's Hospital at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 19 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Jeremy M Wolfe, PHD (6178511166, jwolfe@bwh.harvard.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Response Time (RT) (time frame: through study completion, an average of one year). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Aug 2026.

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