FatigueNCT06933446
Effect of Myofascial Release on Post-Exercise Recovery in Water Polo Athletes
A study testing Myofascial Release and Classic Massage in people with Fatigue, run by Luis Gustavo Lizi Jorge at 1 site in Brazil.
Trial summary
Objective: To assess the acute effect of a myofascial release protocol applied to the adductor muscles of the thigh on functional, biomechanical, and physiological variables. Methods: This study is a randomized, double-blind, two-arm crossover clinical trial that will analyze male water polo athletes aged 16 to 25… Read more about this study
- Who is it for?
- Ages 16 to 25 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Fatigue
- What is being tested?
- Myofascial Release and Classic Massage
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 16 participants
- Where
- 1 siteBrazil
- Study dates
- 1 Feb 2024to 1 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 to 25 years
- Men only
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Male athletes;
- Age 16 to 25 years old;
- Have at least one year of experience in the sport;
- Perform a training load of at least 10 hours per week in the sport;
- Participate in at least regional level competitions
Who cannot join
- Have no reports of muscle injury in the thigh in the three months prior to the study,
- Joint injuries in the hip, such as femoroacetabular impingement or tendinopathies of the tendons of the hip muscles or trochanteric, iliopectineal or ischial bursitis diagnosed by a clinician;
- Do not present a drop in -performance for more than four weeks that could characterize the occurrence of non-functional overreaching or signs of overtraining syndrome
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effect of Release of Trigger Points on Functional Capacity, Biomechanical and Physiological Variables in Recovery After Game Simulation in Water Polo Athletes
Objective: To assess the acute effect of a myofascial release protocol applied to the adductor muscles of the thigh on functional, biomechanical, and physiological variables. Methods: This study is a randomized, double-blind, two-arm crossover clinical trial that will analyze male water polo athletes aged 16 to 25 years recruited from a sports training center in the city of Bauru. Data related to the following parameters will be collected for the physical evaluation: functional performance, through the jump test; biomechanical, through maximum isometric torque of hip adductors, electromyography of the hip and gluteus medius muscles; and physiological, through the analysis of serum markers of muscle damage and inflammation, and heart rate variability. After the initial evaluation, the participants will be randomly divided into two groups: intervention group and sham group. Then, all participants will perform a game simulation. After the game, the participants will receive the intervention designated for each group. For the intervention group, a manual therapy protocol will be applied, based on myofascial release in the thigh region that presents trigger points. For the Sham group, a manual technique, called classic massage, will be applied, with superficial pressure, used to reach only subcutaneous tissues, without acting on muscles and fascia. This protocol will be repeated at four different times, always after the games. After a washout week, the participants will change groups and the data collection protocol will be applied again.
- Conditions
- Fatigue
- Being tested
- Myofascial Release, Classic Massage
- Keywords
- fatigue, physical exertion, post-exercise recovery
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Myofascial ReleaseOther
A myofascial release protocol, applied to the thigh muscles in post-effort recovery in water polo athletes.
Classic MassageOther
Massagem clássica, com pressão superficial, utilizada para atingir apenas tecidos subcutâneos, sem que haja ação sobre músculos e fáscias
| Study group | Role | What they receive |
|---|---|---|
| Myofascial Release | Active comparator | Not described Receives: Other: Classic Massage |
| Classic Massage | Placebo comparator | Not described Receives: Other: Myofascial Release |
What is being measured
The primary outcome is the main question the study is designed to answer.
Maximum Vertical Jump Test
Measured: From enrollment to the end of treatment at 2 weeks
Maximum Voluntary Isometric Torque of the Hip Adductors
Measured: From enrollment to the end of treatment at 2 weeks
Electromyography of Adductors, Gluteus Medius and Transversus Abdominis
Measured: From enrollment to the end of treatment at 2 weeks
Collection of Serum Markers
The markers: creatine kinase (CK; Units of Measure= U/L), lactate dehydrogenase (LDH; Units of Measure= UI/L), myoglobin (Myo; Units of Measure= ng/mL), erythrocyte sedimentation rate (ESR; Units of Measure= mm/h), tumor necrosis factor alpha (TNFA; Units of Measure= Å) will be considered for analysis of muscle damage markers and will be determined through specific kits and following the manufacturer's instructions.
Measured: From enrollment to the end of treatment at 2 weeks
Heart Rate Variability
Heart rate variability (HRV) will be collected, at rest, through a non-invasive method used to measure cardiac autonomic control, to assess the autonomic nervous system (ANS), and the RR interval will be recorded by a portable heart rate monitor.
Measured: From enrollment to the end of treatment at 2 weeks
Secondary outcomes (1)
Effort Control Variables: Subjective Perception of Exertion and Lactate Threshold
To estimate the intensity of the exercise, the method proposed by Foster (1998) will be used, which suggests multiplying the subjective perception of exertion (RPE) of the session by the total duration of the training session (sRPE), with the results expressed in arbitrary units (u.a.). To quantify performance during the game, lactate will be collected at the end of each quarter of the game, through blood collections from the earlobe (25 μL) to analyze the peak lactate concentration ([La-]peak) of the effort.
Measured: From enrollment to the end of treatment at 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Apr 2025
- Study start1 Feb 2024
- Primary completion1 Dec 2026 (estimated)
- Study completion1 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FatigueStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 16 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Luis Gustavo Lizi Jorge
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Luis Gustavo Lizi Jorge, Universidade do Sagrado Coração
- Investigators
- Rebeca Gasparoto Carmezin, Acadêmica em Fisioterapia, Principal investigator, Universidade do Sagrado Coração
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06933446
- Sponsor's protocol ID
- 6.711.962
- Status last verified
- Apr 2025
- First submitted
- 26 Mar 2025
- Last updated
- 18 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Release of Trigger Points on Functional Capacity, Biomechanical and Physiological Variables in Recovery After Game Simulation in Water Polo Athletes
- ClinicalTrials.gov ID
- NCT06933446
- Acronym / sponsor ID
- 6.711.962
- Conditions
- Fatigue
- Keywords
- fatigue, physical exertion, post-exercise recovery
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 16 participants (estimated)
- Lead sponsor
- Luis Gustavo Lizi JorgeUniversity, hospital or other
- Study start
- 1 Feb 2024 (actual)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 1 Dec 2026 (estimated)
- First posted
- 18 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objective: To assess the acute effect of a myofascial release protocol applied to the adductor muscles of the thigh on functional, biomechanical, and physiological variables. Methods: This study is a randomized, double-blind, two-arm crossover clinical trial that will analyze male water polo athletes aged 16 to 25 years recruited from a sports training center in the city of Bauru. Data related to the following parameters will be collected for the physical evaluation: functional performance, through the jump test; biomechanical, through maximum isometric torque of hip adductors, electromyography of the hip and gluteus medius muscles; and physiological, through the analysis of serum markers of muscle damage and inflammation, and heart rate variability. After the initial evaluation, the participants will be randomly divided into two groups: intervention group and sham group. Then, all participants will perform a game simulation. After the game, the participants will receive the intervention designated for each group. For the intervention group, a manual therapy protocol will be applied, based on myofascial release in the thigh region that presents trigger points. For the Sham group, a manual technique, called classic massage, will be applied, with superficial pressure, used to reach only subcutaneous tissues, without acting on muscles and fascia. This protocol will be repeated at four different times, always after the games. After a washout week, the participants will change groups and the data collection protocol will be applied again.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Myofascial Release | Active comparator | Other: Classic Massage |
| Classic Massage | Placebo comparator | Other: Myofascial Release |
Who may qualify
- Ages
- 16 to 25 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Male athletes;
- Age 16 to 25 years old;
- Have at least one year of experience in the sport;
- Perform a training load of at least 10 hours per week in the sport;
- Participate in at least regional level competitions
Key exclusion criteria (3 listed)
- Have no reports of muscle injury in the thigh in the three months prior to the study,
- Joint injuries in the hip, such as femoroacetabular impingement or tendinopathies of the tendons of the hip muscles or trochanteric, iliopectineal or ischial bursitis diagnosed by a clinician;
- Do not present a drop in -performance for more than four weeks that could characterize the occurrence of non-functional overreaching or signs of overtraining syndrome
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Myofascial ReleaseA myofascial release protocol, applied to the thigh muscles in post-effort recovery in water polo athletes. | Other | Classic Massage |
| Classic MassageMassagem clássica, com pressão superficial, utilizada para atingir apenas tecidos subcutâneos, sem que haja ação sobre músculos e fáscias | Other | Myofascial Release |
Primary outcome
Maximum Vertical Jump Test
Time frame: From enrollment to the end of treatment at 2 weeks
Maximum Voluntary Isometric Torque of the Hip Adductors
Time frame: From enrollment to the end of treatment at 2 weeks
Electromyography of Adductors, Gluteus Medius and Transversus Abdominis
Time frame: From enrollment to the end of treatment at 2 weeks
Collection of Serum Markers
Time frame: From enrollment to the end of treatment at 2 weeks
The markers: creatine kinase (CK; Units of Measure= U/L), lactate dehydrogenase (LDH; Units of Measure= UI/L), myoglobin (Myo; Units of Measure= ng/mL), erythrocyte sedimentation rate (ESR; Units of Measure= mm/h), tumor necrosis factor alpha (TNFA; Units of Measure= Å) will be considered for analysis of muscle damage markers and will be determined through specific kits and following the manufacturer's instructions.
Heart Rate Variability
Time frame: From enrollment to the end of treatment at 2 weeks
Heart rate variability (HRV) will be collected, at rest, through a non-invasive method used to measure cardiac autonomic control, to assess the autonomic nervous system (ANS), and the RR interval will be recorded by a portable heart rate monitor.
1 secondary outcome
Effort Control Variables: Subjective Perception of Exertion and Lactate Threshold
Time frame: From enrollment to the end of treatment at 2 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Apr 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rebeca Gasparoto Carmezin, Acadêmica em Fisioterapia principal investigator
Universidade do Sagrado Coração
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Myofascial Release and Classic Massage in people with Fatigue, run by Luis Gustavo Lizi Jorge at 1 site in Brazil.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 18 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Brazil. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Maximum Vertical Jump Test (time frame: From enrollment to the end of treatment at 2 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Apr 2025.