PTSD - Post Traumatic Stress DisorderSTRIDES2NCT06923423
Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
A study testing Group Cognitive Processing Therapy (CPT) in people with PTSD - Post Traumatic Stress Disorder and PTSD and Alcohol Use Disorder, run by University of Arkansas at 6 sites in United States.
Trial summary
Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarcerated. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms
- What is being tested?
- Group Cognitive Processing Therapy (CPT)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 640 participants
- Where
- 6 sitesUnited States
- Study dates
- 7 Jul 2025to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 18 years of age or older
- Able to understand and speak English
- Able to give informed consent
- All items listed in "Inclusion criteria for all participants"
- Be currently incarcerated in one of the prisons that have partnered as study sites
- Have met criteria for a drug use disorder in the year prior to their current incarceration (≥ 2 symptoms on a DSM-5 drug use disorder checklist)
Show all 16Show fewer
- Have used drugs in the 30 days prior to their current incarceration
- Have a history of traumatic event exposure
- Endorse clinically significant posttraumatic stress symptoms (score ≥ 4 on the Primary Care PTSD Screen for DSM-5; PC-PTSD-5)
- Expect to be incarcerated for at least long enough to complete CPT-CJ as it is being implemented at the particular site (i.e., anticipated to be ~3 months, but will depend on dates associated with next available intervention group)
- Expect to be released from prison within 12 months following the end of treatment (i.e., within ~15 months of the pre-treatment assessment)
- Willing to consent to randomization to treatment condition
- Exclusion criteria for prisoners (additional requirements assessed during pre-treatment assessments or indicated by prison staff; will result in being withdrawn from the study prior to randomization by the PI):
- Unable to provide any locator information for post-release assessments
- Determined to be releasing sooner than would allow the individual to complete CPT-CJ
- Determined to have an unavoidable scheduling conflict or facility restriction (e.g., disciplinary, medical) that would prevent participation in CPT-CJ. Of note, if the scheduling conflict or facility restriction is expected to resolve following the next round of randomization at the study site, the participant may be put on "hold for next round" status rather than withdrawn unless other exclusionary criteria would be met by that time (e.g., release).
Who cannot join
None listed.
Trial locations and contacts
6 sites in 1 country. Contact the study team or a site near you to ask about taking part.
6 sites in 1 country
United States6 sites, 6 recruiting
- Recruiting
North Dakota State Penitentiary (NDSP)
Bismarck, North Dakota, 58501
- Recruiting
Heart River Correctional Center (HRCC)
Bismarck, North Dakota, 58502
- Not yet recruiting
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
Melissa J Zielinski, PhD, 501-526-8229, MJZielinski@uams.edu
Melissa J Zielinski, PhD
- Recruiting
Northeast Arkansas Community Corrections Center (NEACC)
Osceola, Arkansas, 72370
- Recruiting
Southwest Arkansas Community Correction Center
Texarkana, Arkansas, 71854
John Miners
- Recruiting
East Central Arkansas Community Correction Center
West Memphis, Arkansas, 72301
Tameka Coleman
About this study
Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarcerated. Posttraumatic stress symptoms (PTSS) are often a result of trauma and are linked to more severe drug use, higher rates of relapse, and increased crime. PTSS and substance use disorder (SUD) each raise the chances of new arrests for people who are justice-involved, showing that addressing trauma and addiction could help reduce repeat offenses and the costs of incarceration. However, treatments for PTSS are rarely available in prisons, and there is little research on whether providing therapy for PTSS in prison can lower drug use, PTSS, or crime after release.
The goal of this clinical trial is to see if trauma-focused group therapy (CPT) provided while in prison, can help people after release from prison. The therapy has been adapted for use in prisons (CPT-CJ) and will be compared to trauma focused therapy delivered via a self-help workbook
Read more
This study will:
- test whether a trauma-focused group therapy (CPT-CJ) can reduce post-incarceration drug and alcohol use, mental health issues, and drug-related crime, compared to trauma-focused self-help,
- evaluate a strategy called implementation facilitation, which helps support the use of this therapy in prisons, and
- measure the cost of the therapies and support strategies to help plan for future expansion.
Incarcerated participants (N = 640; 50% female) will be enrolled from ~10 prisons in ~5 states, ensuring variability in population and setting characteristics. They will:
- take surveys and answer questions up to 5 times (before starting treatment, right after getting treatment, right before leaving prison, 3 months after leaving prison and 6 months after leaving prison)
- complete CPT group therapy or self-help therapy
- provide urine samples 3 months and 6 months after leaving prison
Prison stakeholders (e.g., prison staff, prison leadership, governmental officials; N = ~15 per site) who will be purposively sampled based on their role in CPT-CJ implementation will also participate in some surveys.
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD), Depression, Mental Health
- Being tested
- Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
- Keywords
- Post traumatic Stress Disorder, Post traumatic Stress Symptoms, Substance Use, Substance Use Disorder, Cognitive Processing Therapy, Cognitive Processing Therapy for Criminal Justice Setting, Trauma focused self help, Facilitation, Implementation Facilitation, Implementation, Cost Estimation and Offsets, Drug Use Disorder, Alcohol Use Disorder, Trauma, Depression, Adult, Incarcerated, Prison, Imprisonment, Intervention
- Medical subject headings
- Combat Disorders, Stress Disorders, Post-Traumatic, Alcoholism, Substance-Related Disorders, Depression, Psychological Well-Being, Wounds and Injuries, Stress Disorders, Traumatic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group Cognitive Processing Therapy (CPT)Behavioural
Also called CPT-CJ
Participants in CPT group therapy will learn about trauma and how to change upsetting thoughts related to it. Participants will attend up to a total of 12 sessions held 1-2x/week for 90 minutes. No more than 10 participants will be in a group. In this study, CPT provided is a version that was adapted for prisons.
Control Group Individual trauma focused self-help via workbookBehavioural
The self-help therapy is a therapy that people do on their own using a workbook. By reading and doing practice assignments in the workbook, people can learn skills to recover from trauma.
| Study group | Role | What they receive |
|---|---|---|
| Group Cognitive Processing Therapy (CPT) | Active comparator | Participants in CPT group therapy will learn about trauma and how to change upsetting thoughts related to it. Participants will attend up to a total of 12 sessions held 1-2x/week for 90 minutes. No more than 10 participants will be in a group. In this study, CPT provided is a version that was adapted for prisons (CPT-CJ). Receives: Behavioral: Group Cognitive Processing Therapy (CPT) |
| Individual trauma focused self-help via workbook | Active comparator | Participants in the trauma-focused self-help therapy will independently read and do practice assignments in a workbook to learn skills to recover from trauma. Receives: Behavioral: Control Group Individual trauma focused self-help via workbook |
What is being measured
The primary outcome is the main question the study is designed to answer.
Drug Use Frequency (Count)
Participants complete a Timeline Follow Back Interview assessment of illicit drug use during the previous 30 days at 3- \& 6-months post-release from prison. The total number of days of drug use will be summed to represent drug use frequency.
Measured: 3- and 6-month post-release from prison
Drug use (Binary)
Participants complete a Timeline Follow Back Interview assessment of illicit drug use during the previous 30 days at 3- \& 6-months post-release from prison. The total number of days of drug use will be dichotomized to indicate presence or absence of drug use since release.
Measured: 3- and 6-month post-release from prison
Posttraumatic Stress Symptom Severity (Sum)
Participants complete the PTSD Checklist for DSM-5 (PCL-5) at all assessments to examine change the effectiveness of the intervention and control groups on posttraumatic stress symptom severity. Scores range from 0-80 with higher scores indicating more severe PTSD symptoms.
Measured: Pre-treatment assessments will be ~2 wks before tx starts; post-treatment will be ~2 wks after tx ends; pre-release will be ~3 days before release; post-release follow-ups will be 3- and 6-mo after prison exist
Treatment fidelity (ratio)
The ratio of the number of CPT-CJ components delivered to the number of CPT-CJ components planned per completed fidelity monitoring templates.
Measured: Fidelity assessments will be done during the active treatment period which can be as short as 6 weeks to as long as 3 months for participants. The active treatment period is expected to span 1.5 years at each site.
Secondary outcomes (18)
Drug Use Disorder Symptom Severity (Count)
Participants will complete a DSM-5 checklist of drug use disorder diagnostic criteria. The checklist can result in a maximum score of 11, with scores of 2 or greater indicating the presence of symptoms likely to meet diagnostic criteria. Scores will represent the total number of symptoms currently endorsed.
Measured: 3- and 6-months post-release from prison
Drug Use Disorder (Binary)
Participants will complete a DSM-5 checklist of drug use disorder diagnostic criteria. The checklist can result in a maximum score of 11, with scores of 2 or greater indicating the presence of symptoms likely to meet diagnostic criteria. Scores will represent the total number of symptoms currently endorsed. Sum score will be used to determine substance use disorder presence (i.e., scores ≥ 2) or absence (scores of 0-1).
Measured: 3- and 6-months post-release from prison
Depressive Symptom Severity (Sum)
Participants will complete the Patient Health Questionnaire - 8-item (PHQ-8) at all assessments to examine change the effectiveness of the intervention and control groups on depressive symptom severity. Scores range from 0-24 with higher scores indicating more severe depressive symptoms.
Measured: Pre-treatment assessments will be done ~2 wks before tx starts; post-treatment will be ~2 wks after tx ends; pre-release will be ~3 days before release; post-release follow-ups will be ~3- and ~6-mo after prison exit
Alcohol Use Frequency (Count)
Participants will complete a Timeline Follow Back Interview assessment of alcohol use during the previous 30 days at both 3- and 6-months post-release from prison. The total number of days of alcohol use will be summed to represent drug use frequency.
Measured: 3- and 6-months post-release from prison
Alcohol Use (Binary)
Participants will complete a Timeline Follow Back Interview assessment of alcohol use during the previous 30 days at both 3- and 6-months post-release from prison. The total number of days of alcohol use will be dichotomized to indicate presence or absence of alcohol use since release.
Measured: 3- and 6-months post-release from prison
Alcohol Use Disorder Symptom Severity (Count)
Participants will complete a DSM-5 checklist of alcohol use disorder diagnostic criteria. The checklist can result in a maximum score of 11, with scores of 2 or greater indicating the presence of symptoms likely to meet diagnostic criteria. Scores will represent the total number of symptoms currently endorsed.
Measured: 3- and 6-months post-release from prison
Alcohol Use Disorder (Binary)
Participants will complete a DSM-5 checklist of alcohol use disorder diagnostic criteria. The checklist can result in a maximum score of 11, with scores of 2 or greater indicating the presence of symptoms likely to meet diagnostic criteria. Scores will represent the total number of symptoms currently endorsed. Sum score will be used to determine substance use disorder presence (i.e., scores ≥ 2) or absence (scores of 0-1).
Measured: 3- and 6-months post-release from prison
Drug-Related Crime Frequency (Count)
Sum of new arrests and new convictions for drug charges based on the Criminal and Legal Activities Form and, if sufficient data is available, administrative records.
Measured: 6-months post-release from prison
Drug Related Crime (Binary)
Presence or absence of any new arrests or new convictions for drug charges based on the Criminal and Legal Activities Form and, if sufficient data is available, administrative records.
Measured: 6-months post-release from prison
Substance-Related Disciplinary Violations (Count)
Sum of substance-related disciplinary violations received while incarcerated per administrative records
Measured: Interval between treatment completion and release from incarceration, which could be as short as 1 day and as long as ~2 years
Substance-Related Disciplinary Violations (Binary)
Presence or absence of any substance-related disciplinary violations received while incarcerated per administrative records.
Measured: Interval between treatment completion and release from incarceration, which could be as short as 1 day and as long as ~2 years
Positive Urine Drug Screens (Binary)
Presence or absence of any positive urine drug screens following release from prison per department of corrections administrative records.
Measured: 3- and 6-months post-release from prison
Treatment Acceptability (mean)
Prison residents and stakeholders will complete the Acceptability of Intervention Measure (AIM) to index treatment acceptability. Mean scores on the AIM range from 1-5, with higher scores indicating greater intervention acceptability.
Measured: Post-treatment assessments will be completed 2 weeks after treatment ends (for residents). Immediately and 12-months post-implementation (for prison stakeholders)
Treatment Acceptability (sum)
Prison residents will complete the Client Satisfaction Questionnaire (CSQ-8) as an additional index of treatment acceptability. Sum scores on the CSQ-8 range from 8-32, with higher scores indicating greater intervention acceptability.
Measured: Administered at post-treatment assessment, which will be completed ~2 weeks after treatment ends
Treatment appropriateness (mean)
The Intervention Appropriateness Measure (IAM) will be completed by both prison residents and prison stakeholders. Mean scores on the IAM range from 1-5, with higher scores indicating greater intervention appropriateness.
Measured: Post-treatment assessments will be completed ~2 weeks after treatment ends (for residents). Immediately and 12-months post-implementation (for prison stakeholders)
Treatment feasibility (mean)
The Feasibility of Intervention Measure (FIM) will be completed by prison stakeholders to index treatment feasibility. Mean scores on the FIM range from 1-5, with higher scores indicating greater intervention feasibility.
Measured: Immediately and 12-months post-implementation
Treatment adoption (ratio)
Ratio of patients who completed CPT-CJ to the number who were randomized
Measured: Treatment adoption assessment will be done during the active treatment period, which can be as short as 6 weeks to as long as 3 months for participants. The active treatment period is expected to span 1.5 years at each site
Treatment sustainability (ratio)
The number of sites of total that are maintaining or increasing in CPT-CJ provision with high fidelity after implementation facilitation support is withdrawn.
Measured: 1-year post-implementation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Apr 2025
- Study start7 Jul 2025
- Primary completionDec 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PTSD - Post Traumatic Stress DisorderStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 640 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Arkansas
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Sponsor
- Investigators
- Melissa J Zielinski, PhD, Principal investigator, University of Arkansas
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06923423
- Sponsor's protocol ID
- 297770
- Other IDs
- R01DA059549
- Acronym
- STRIDES2
- Status last verified
- Jan 2026
- First submitted
- 3 Feb 2025
- Last updated
- 21 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 21 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons
- ClinicalTrials.gov ID
- NCT06923423
- Acronym / sponsor ID
- STRIDES2 / 297770
- Conditions
- PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD), Depression, Mental Health
- Keywords
- Post traumatic Stress Disorder, Post traumatic Stress Symptoms, Substance Use, Substance Use Disorder, Cognitive Processing Therapy, Cognitive Processing Therapy for Criminal Justice Setting, Trauma focused self help, Facilitation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 640 participants (estimated)
- Lead sponsor
- University of ArkansasUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- 7 Jul 2025 (actual)
- Primary completion
- Dec 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 11 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarcerated. Posttraumatic stress symptoms (PTSS) are often a result of trauma and are linked to more severe drug use, higher rates of relapse, and increased crime. PTSS and substance use disorder (SUD) each raise the chances of new arrests for people who are justice-involved, showing that addressing trauma and addiction could help reduce repeat offenses and the costs of incarceration. However, treatments for PTSS are rarely available in prisons, and there is little research on whether providing therapy for PTSS in prison can lower drug use, PTSS, or crime after release.
The goal of this clinical trial is to see if trauma-focused group therapy (CPT) provided while in prison, can help people after release from prison. The therapy has been adapted for use in prisons (CPT-CJ) and will be compared to trauma focused therapy delivered via a self-help workbook
This study will:
- test whether a trauma-focused group therapy (CPT-CJ) can reduce post-incarceration drug and alcohol use, mental health issues, and drug-related crime, compared to trauma-focused self-help,
- evaluate a strategy called implementation facilitation, which helps support the use of this therapy in prisons, and
- measure the cost of the therapies and support strategies to help plan for future expansion.
Incarcerated participants (N = 640; 50% female) will be enrolled from ~10 prisons in ~5 states, ensuring variability in population and setting characteristics. They will:
- take surveys and answer questions up to 5 times (before starting treatment, right after getting treatment, right before leaving prison, 3 months after leaving prison and 6 months after leaving prison)
- complete CPT group therapy or self-help therapy
- provide urine samples 3 months and 6 months after leaving prison
Prison stakeholders (e.g., prison staff, prison leadership, governmental officials; N = ~15 per site) who will be purposively sampled based on their role in CPT-CJ implementation will also participate in some surveys.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group Cognitive Processing Therapy (CPT) | Active comparator | Behavioral: Group Cognitive Processing Therapy (CPT)Participants in CPT group therapy will learn about trauma and how to change upsetting thoughts related to it. Participants will attend up to a total of 12 sessions held 1-2x/week for 90 minutes. No more than 10 participants will be in a group. In this study, CPT provided is a version that was adapted for prisons (CPT-CJ). |
| Individual trauma focused self-help via workbook | Active comparator | Behavioral: Control Group Individual trauma focused self-help via workbookParticipants in the trauma-focused self-help therapy will independently read and do practice assignments in a workbook to learn skills to recover from trauma. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (16 listed)
- 18 years of age or older
- Able to understand and speak English
- Able to give informed consent
- All items listed in "Inclusion criteria for all participants"
- Be currently incarcerated in one of the prisons that have partnered as study sites
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group Cognitive Processing Therapy (CPT)Also: CPT-CJParticipants in CPT group therapy will learn about trauma and how to change upsetting thoughts related to it. Participants will attend up to a total of 12 sessions held 1-2x/week for 90 minutes. No more than 10 participants will be in a group. In this study, CPT provided is a version that was adapted for prisons. | Behavioural | Group Cognitive Processing Therapy (CPT) |
| Control Group Individual trauma focused self-help via workbookThe self-help therapy is a therapy that people do on their own using a workbook. By reading and doing practice assignments in the workbook, people can learn skills to recover from trauma. | Behavioural | Individual trauma focused self-help via workbook |
Primary outcome
Drug Use Frequency (Count)
Time frame: 3- and 6-month post-release from prison
Participants complete a Timeline Follow Back Interview assessment of illicit drug use during the previous 30 days at 3- \& 6-months post-release from prison. The total number of days of drug use will be summed to represent drug use frequency.
Drug use (Binary)
Time frame: 3- and 6-month post-release from prison
Participants complete a Timeline Follow Back Interview assessment of illicit drug use during the previous 30 days at 3- \& 6-months post-release from prison. The total number of days of drug use will be dichotomized to indicate presence or absence of drug use since release.
Posttraumatic Stress Symptom Severity (Sum)
Time frame: Pre-treatment assessments will be ~2 wks before tx starts; post-treatment will be ~2 wks after tx ends; pre-release will be ~3 days before release; post-release follow-ups will be 3- and 6-mo after prison exist
Participants complete the PTSD Checklist for DSM-5 (PCL-5) at all assessments to examine change the effectiveness of the intervention and control groups on posttraumatic stress symptom severity. Scores range from 0-80 with higher scores indicating more severe PTSD symptoms.
Treatment fidelity (ratio)
Time frame: Fidelity assessments will be done during the active treatment period which can be as short as 6 weeks to as long as 3 months for participants. The active treatment period is expected to span 1.5 years at each site.
The ratio of the number of CPT-CJ components delivered to the number of CPT-CJ components planned per completed fidelity monitoring templates.
18 secondary outcomes
Drug Use Disorder Symptom Severity (Count)
Time frame: 3- and 6-months post-release from prison
Drug Use Disorder (Binary)
Time frame: 3- and 6-months post-release from prison
Depressive Symptom Severity (Sum)
Time frame: Pre-treatment assessments will be done ~2 wks before tx starts; post-treatment will be ~2 wks after tx ends; pre-release will be ~3 days before release; post-release follow-ups will be ~3- and ~6-mo after prison exit
Alcohol Use Frequency (Count)
Time frame: 3- and 6-months post-release from prison
Alcohol Use (Binary)
Time frame: 3- and 6-months post-release from prison
Alcohol Use Disorder Symptom Severity (Count)
Time frame: 3- and 6-months post-release from prison
Alcohol Use Disorder (Binary)
Time frame: 3- and 6-months post-release from prison
Drug-Related Crime Frequency (Count)
Time frame: 6-months post-release from prison
Drug Related Crime (Binary)
Time frame: 6-months post-release from prison
Substance-Related Disciplinary Violations (Count)
Time frame: Interval between treatment completion and release from incarceration, which could be as short as 1 day and as long as ~2 years
Substance-Related Disciplinary Violations (Binary)
Time frame: Interval between treatment completion and release from incarceration, which could be as short as 1 day and as long as ~2 years
Positive Urine Drug Screens (Binary)
Time frame: 3- and 6-months post-release from prison
Treatment Acceptability (mean)
Time frame: Post-treatment assessments will be completed 2 weeks after treatment ends (for residents). Immediately and 12-months post-implementation (for prison stakeholders)
Treatment Acceptability (sum)
Time frame: Administered at post-treatment assessment, which will be completed ~2 weeks after treatment ends
Treatment appropriateness (mean)
Time frame: Post-treatment assessments will be completed ~2 weeks after treatment ends (for residents). Immediately and 12-months post-implementation (for prison stakeholders)
Treatment feasibility (mean)
Time frame: Immediately and 12-months post-implementation
Treatment adoption (ratio)
Time frame: Treatment adoption assessment will be done during the active treatment period, which can be as short as 6 weeks to as long as 3 months for participants. The active treatment period is expected to span 1.5 years at each site
Treatment sustainability (ratio)
Time frame: 1-year post-implementation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jan 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Melissa J Zielinski, PhD principal investigator
University of Arkansas
6 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group Cognitive Processing Therapy (CPT) in people with PTSD - Post Traumatic Stress Disorder and PTSD and Alcohol Use Disorder, run by University of Arkansas at 6 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 16 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 6 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Melissa J Zielinski, PhD (501-526-8229, MJZielinski@uams.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Drug Use Frequency (Count) (time frame: 3- and 6-month post-release from prison). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jan 2026.