Umbilical Cord Coiling Index and Fetal Cardiac FunctionsNCT06915051
The Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.
An observational study of Umbilical Cord Coiling Index and Fetal Cardiac Functions, run by Sanliurfa Education and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. Read more about this study
- Who is it for?
- Ages 18 to 50 years, women only
- Conditions the study is for
- Umbilical Cord Coiling Index and Fetal Cardiac Functions
- What is being tested?
- Determining the relationship between the coiling number and fetal echocardiography findings.
- How many people
- 202 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Mar 2025to 30 Aug 2025
- How long will I take part?
- 4 Months
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- Women only
- No healthy volunteers
- Adult
Study population: Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care will be included.
Who may be able to join
- -Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care.
Who cannot join
- Multiple pregnancy
- Preterm rupture of membranes
- Chorioamnionitis
- Placental abruption
- Severe fetal growth restriction
- Congenital anomalies of the fetus
Show all 9Show fewer
- Preeclampsia
- Oligohydramnios
- Maternal diabetes.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Sanliurfa Education and Research Hospital
Sanliurfa
About this study
Official title: Evaluation of the Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.
The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. In recent years, there has been a renewed interest in the umbilical cord, and several articles have been published regarding the number of coils.In this study, the relationship between the umbilical cord coiling index and fetal cardiac functions was evaluated.
- Being tested
- Determining the relationship between the coiling number and fetal echocardiography findings.
- Keywords
- Umbilical cord coiling index, fetal cardiac functions, umbilical cord, fetal circulation
- Medical subject headings
- Persistent Fetal Circulation Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Determining the relationship between the coiling number and fetal echocardiography findings.Diagnostic test
Fetal echocardiography findings to be performed simultaneously with the determination of the coiling number.
| Study group | Role | What they receive |
|---|---|---|
| This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated. | Not described Receives: Diagnostic Test: Determining the relationship between the coiling number and fetal echocardiography findings. |
What is being measured
The primary outcome is the main question the study is designed to answer.
The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings.
This study will be a single-center study conducted on two hundred randomly selected pregnant women with uncomplicated singleton pregnancies in the late second trimester (20-24 weeks) who visit our hospital's perinatology outpatient clinic for routine prenatal check-ups. The umbilical cord coiling number and fetal cardiac function measurements will be performed within one hour by the same maternal-fetal medicine specialist.To optimize the quality of Doppler waveforms when assessing vascular structures, measurements will be obtained in the absence of uterine contractions and fetal activity, with an insonation angle as close to zero as possible and less than 30.Three parameters will be used to assess cardiac function:
- Diastolic function
- Systolic function
- Both systolic and diastolic function
Measured: The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Apr 2025
- Study start1 Mar 2025
- Primary completion15 Jun 2025
- Study completion30 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Umbilical Cord Coiling Index and Fetal Cardiac FunctionsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 202 participants (actual)
- Target duration
- 4 Months
Sponsor and investigators
- Lead sponsor
- Sanliurfa Education and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06915051
- Sponsor's protocol ID
- SEAH-COİLİNG
- Status last verified
- Nov 2025
- First submitted
- 25 Mar 2025
- Last updated
- 18 Nov 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Nov 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Relationship Between Umbilical Cord Coiling Index and Fetal Cardiac Functions.
- ClinicalTrials.gov ID
- NCT06915051
- Acronym / sponsor ID
- SEAH-COİLİNG
- Keywords
- Umbilical cord coiling index, fetal cardiac functions, umbilical cord, fetal circulation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 202 participants (actual)
- Lead sponsor
- Sanliurfa Education and Research HospitalOther government
- Study start
- 1 Mar 2025 (actual)
- Primary completion
- 15 Jun 2025 (actual)
- Study completion
- 30 Aug 2025 (actual)
- First posted
- 8 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The maximum efficiency of umbilical cord blood flow depends on a specific number of coils. With modern ultrasound techniques, investigators can now detect cord abnormalities even before birth. In recent years, there has been a renewed interest in the umbilical cord, and several articles have been published regarding the number of coils.In this study, the relationship between the umbilical cord coiling index and fetal cardiac functions was evaluated.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Target follow-up
- 4 Months
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated. | – | Diagnostic Test: Determining the relationship between the coiling number and fetal echocardiography findings. |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care will be included.
Key inclusion criteria (1 listed)
- -Singleton uncomplicated pregnancies between 20-24 weeks seeking routine antenatal care.
Key exclusion criteria (9 listed)
- Multiple pregnancy
- Preterm rupture of membranes
- Chorioamnionitis
- Placental abruption
- Severe fetal growth restriction
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Determining the relationship between the coiling number and fetal echocardiography findings.Fetal echocardiography findings to be performed simultaneously with the determination of the coiling number. | Diagnostic test | This is a single-center study conducted on 200 randomly selected pregnant women with uncomplicated. |
Primary outcome
The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings.
Time frame: The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.
This study will be a single-center study conducted on two hundred randomly selected pregnant women with uncomplicated singleton pregnancies in the late second trimester (20-24 weeks) who visit our hospital's perinatology outpatient clinic for routine prenatal check-ups. The umbilical cord coiling number and fetal cardiac function measurements will be performed within one hour by the same maternal-fetal medicine specialist.To optimize the quality of Doppler waveforms when assessing vascular structures, measurements will be obtained in the absence of uterine contractions and fetal activity, with an insonation angle as close to zero as possible and less than 30.Three parameters will be used to assess cardiac function: 1. Diastolic function 2. Systolic function 3. Both systolic and diastolic function
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Nov 2025.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Umbilical Cord Coiling Index and Fetal Cardiac Functions, run by Sanliurfa Education and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Nov 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The correlation between the fetal umbilical cord coiling number and the concurrently performed fetal echocardiography findings. (time frame: The correlation between the fetal umbilical cord coiling index and the echocardiographic findings of the fetus within the first hour will be investigated.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Nov 2025.