Hypertensive ComplicationNCT06913478
Evaluation Of Effect of Axial Length on Cup-To-Disc Ratio Among Non- Glaucomatous Hypertensive Patients
An observational study of Hypertensive Complication, run by Superior University at 1 site in Pakistan.
Trial summary
This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used. Read more about this study
- Who is it for?
- Ages 18 to 70 years
- Conditions the study is for
- Hypertensive Complication
- How many people
- 94 participants
- Where
- 1 sitePakistan
- Study dates
- 20 Mar 2025to 20 Feb 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: his observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital
Who may be able to join
- Male and female patients diagnosed with systemic hypertension for at least 1 year.
- Age between 18-70 years.
- Normal intraocular pressure (IOP<-21mmhg)
- Axial length between 21mm and 26mm (to exclude extreme refractive errors)
Who cannot join
- History of glaucoma or ocular hypertension.
- High myopia (<-6.00 D) or hyperopia (>+6.00D).
- History of ocular surgery, trauma, or retinal diseases.
- Any optic nerve diseases.
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Alshifa eye clinic Ali Pur chattha
Chak One Hundred Seventy-five Nine Left, Punjab Province
About this study
This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used.
Read the detailed description
Patients aged 18-70 years with systemic hypertension for at least one year and normal intraocular pressure will be included. Exclusion criteria include glaucoma, high myopia, hyperopia, ocular surgery, trauma, and optic nerve diseases. Axial length will be measured using optical biometry or A-scan ultrasonography, while the cup-to-disc ratio will be assessed through fundus examination using a slit lamp biomicroscope with a +90D lens or optical coherence tomography (OCT). Data will be meticulously documented, including patient demographics and medical history. The study will be completed within six months after approval, ensuring accurate and standardized measurements for reliable results.
- Conditions
- Hypertensive Complication
What is being measured
The primary outcome is the main question the study is designed to answer.
Axial length measured by biometry and CD ratio by slitlamp
The axial length, measured in millimeters, is defined as the distance from the anterior surface of the cornea to the retinal pigment epithelium. The axial length can be measured using either ultrasound biometry (accomplished via direct contact or immersion) or optical biometry
Measured: 12 Months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Apr 2025
- Study start20 Mar 2025
- Primary completion20 Jun 2025 (estimated)
- Study completion20 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hypertensive ComplicationStudies of the same condition, open and under way.
- More trials run by Superior UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Retrospective
- Enrolment
- 94 participants (actual)
Sponsor and investigators
- Lead sponsor
- Superior University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Muhammad Naveed Babur, Superior University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06913478
- Sponsor's protocol ID
- MSRSW/Batch-Fall23/802
- Status last verified
- Mar 2025
- First submitted
- 29 Mar 2025
- Last updated
- 6 Apr 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation Of Effect of Axial Length on Cup-To-Disc Ratio Among Non- Glaucomatous Hypertensive Patients
- ClinicalTrials.gov ID
- NCT06913478
- Acronym / sponsor ID
- MSRSW/Batch-Fall23/802
- Conditions
- Hypertensive Complication
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 94 participants (actual)
- Lead sponsor
- Superior UniversityUniversity, hospital or other
- Study start
- 20 Mar 2025 (actual)
- Primary completion
- 20 Jun 2025 (estimated)
- Study completion
- 20 Feb 2026 (estimated)
- First posted
- 6 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital, with a sample size of 104 participants. A purposive sampling technique will be used.
Detailed description
Patients aged 18-70 years with systemic hypertension for at least one year and normal intraocular pressure will be included. Exclusion criteria include glaucoma, high myopia, hyperopia, ocular surgery, trauma, and optic nerve diseases. Axial length will be measured using optical biometry or A-scan ultrasonography, while the cup-to-disc ratio will be assessed through fundus examination using a slit lamp biomicroscope with a +90D lens or optical coherence tomography (OCT). Data will be meticulously documented, including patient demographics and medical history. The study will be completed within six months after approval, ensuring accurate and standardized measurements for reliable results.
Study design
- Observational model
- Case-control
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- his observational cross-sectional study aims to compare the effect of axial length on the cup-to-disc ratio in non-glaucomatous hypertensive patients. Data will be collected from Khursheed Begum Eye Hospital and LRBT Hospital
Key inclusion criteria (4 listed)
- Male and female patients diagnosed with systemic hypertension for at least 1 year.
- Age between 18-70 years.
- Normal intraocular pressure (IOP<-21mmhg)
- Axial length between 21mm and 26mm (to exclude extreme refractive errors)
Key exclusion criteria (4 listed)
- History of glaucoma or ocular hypertension.
- High myopia (<-6.00 D) or hyperopia (>+6.00D).
- History of ocular surgery, trauma, or retinal diseases.
- Any optic nerve diseases.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Axial length measured by biometry and CD ratio by slitlamp
Time frame: 12 Months
The axial length, measured in millimeters, is defined as the distance from the anterior surface of the cornea to the retinal pigment epithelium. The axial length can be measured using either ultrasound biometry (accomplished via direct contact or immersion) or optical biometry
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Apr 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hypertensive Complication, run by Superior University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 6 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Axial length measured by biometry and CD ratio by slitlamp (time frame: 12 Months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Apr 2025.