Rotator Cuff SyndromeNCT06899945
Effects of Vibration Frequencies in Rotator Cuff Syndrome
A study testing a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) and conventional physiotherapy program in people with Rotator Cuff Syndrome and Vibration Therapy, run by Medipol University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to investigate the effects of vibration therapy applied at different frequencies using a percussion massage gun on pain, range of motion (ROM), functionality, joint position sense, and quality of life in individuals with rotator cuff syndrome. Read more about this study
- Who is it for?
- Ages 30 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Rotator Cuff Syndrome, Vibration Therapy
- What is being tested?
- a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) and conventional physiotherapy program
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 25 Mar 2025to 20 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Individuals diagnosed with rotator cuff lesion,
- Experiencing shoulder pain for at least 3 weeks,
- Aged between 30-60 years,
- Having restricted shoulder range of motion.
Who cannot join
- Individuals with an additional orthopedic or neurological disorder affecting the shoulder,
- Those with a history of previous shoulder trauma,
- Individuals who have participated in a physiotherapy program within the last 3 months,
- Those unable to tolerate vibration therapy.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effects of Vibration Therapy at Different Frequencies on Pain, Range of Motion, Functionality, Joint Position Sense, and Quality of Life in Individuals With Rotator Cuff Syndrome
This study aims to investigate the effects of vibration therapy applied at different frequencies using a percussion massage gun on pain, range of motion (ROM), functionality, joint position sense, and quality of life in individuals with rotator cuff syndrome.
Rotator cuff syndrome is a common shoulder disorder caused by excessive use, muscle weakness, trauma, or instability, leading to pain, restricted movement, and reduced functional capacity. Although percussion massage therapy has gained popularity for its potential therapeutic benefits, there is limited scientific evidence on its effectiveness in improving ROM, pain reduction, and functional outcomes.
Read more
A total of 48 participants diagnosed with rotator cuff lesions will be included in the study and divided into three groups:
Vibration Group (33 Hz) Vibration Group (16.7 Hz) Control Group (Conventional Physiotherapy)
The intervention will include:
Conventional physiotherapy exercises applied to all groups, Vibration therapy with a percussion massage gun applied to the experimental groups, targeting the deltoid, supraspinatus, infraspinatus, and teres minor muscles for three minutes per muscle, three times per week for three weeks.
Outcome Measures:
Pain: Visual Analog Scale (VAS) ROM \& Joint Position Sense: Measured using the Goniometer Pro mobile application Functionality: Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire Quality of Life: Rotator Cuff Quality of Life (RC-QoL) questionnaire
Hypotheses:
Vibration therapy at different frequencies will significantly impact pain, ROM, functionality, joint position sense, and quality of life.
33 Hz vibration therapy will be more effective than 16.7 Hz in improving outcomes.
The data will be analyzed using SPSS 25, with statistical tests applied based on data distribution. This research aims to contribute to the understanding of vibration therapy's role in managing rotator cuff syndrome and its effectiveness in clinical rehabilitation.
Read the detailed description
Rotator cuff syndrome is a common shoulder disorder caused by excessive use, muscle weakness, trauma, or instability. It often results in pain, restricted movement, and reduced functional capacity. The condition is associated with subacromial space compression, leading to tendinitis, partial tears, or full rupture, which affects daily activities and overall quality of life.
Percussion massage therapy is an emerging treatment method that combines elements of traditional massage and vibration therapy. Introduced in the 1950s by Robert Fulford, it was later developed into handheld devices for self-administered and professional use. Percussion therapy is believed to reduce pain, enhance circulation, improve tissue healing, decrease muscle spasms, and increase joint range of motion (ROM).
However, scientific evidence regarding its effectiveness, particularly in rotator cuff syndrome, remains limited. This study aims to investigate the effects of different frequencies of vibration therapy applied with a percussion massage gun on pain, ROM, functionality, joint position sense, and quality of life in individuals with rotator cuff syndrome.
- Conditions
- Rotator Cuff Syndrome, Vibration Therapy
- Being tested
- a percussion massage gun (Hypervolt device (Hyperice, CA, USA)), conventional physiotherapy program
- Keywords
- Rotator Cuff Syndrome, Vibration Therapy, Pain, Functionality, Proprioception, Quality of life
- Medical subject headings
- Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
a percussion massage gun (Hypervolt device (Hyperice, CA, USA))Device
Vibration application will be applied to the individuals in this group in addition to conventional methods. Vibration application will be applied to the deltoid, supraspinatus, infraspinatus, and teres minor muscles with a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) along the origo-insertio line for 3 minutes for each muscle group. Vibration application will be performed using the soft head of the percussion massage gun. Vibration therapy will be applied 3 days a week for 3 weeks.
conventional physiotherapy programOther
Participants in the conventional physiotherapy program will follow a 3-week exercise plan, with sessions 5 days per week, each lasting 30 minutes under physiotherapist supervision.
Treatment includes:
TENS therapy (20 min, 100 Hz) on the painful area. Wand exercises for flexion, abduction, extension, internal, and external rotation (10 reps/set).
Codman exercises for flexion, abduction, and circular movements (10 reps/set). Active \& passive stretching for flexion, abduction, internal, and external rotation (10 reps/set).
Finger ladder exercises for flexion and abduction (10 reps/set). Strengthening with a theraband for flexion, abduction, external/internal rotation, and extension, adjusted based on progress (10 reps/set).
This exercise program will be applied to all study groups.
| Study group | Role | What they receive |
|---|---|---|
| Control Group (Conventional Physiotherapy) | Active comparator | Participants in the control group will receive only conventional physiotherapy without vibration therapy. This ensures a baseline comparison to assess the effectiveness of vibration therapy.
Treatment Modalities:
TENS therapy (20 minutes, 100 Hz) Mobility exercises (wand exercises, Codman exercises, active/passive stretching) Strengthening exercises (theraband-based training) Frequency: 5 sessions per week Total Treatment Period: 3 weeks Receives: Other: conventional physiotherapy program |
| Vibration Therapy (16.7 Hz) Group | Experimental | This group will receive vibration therapy at 16.7 Hz using a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) along with a standard physiotherapy program. The treatment protocol mirrors the 33 Hz group, except for the vibration frequency.
Duration: 3 minutes per muscle Frequency: 3 times per week Total Treatment Period: 3 weeks Additional Treatment: Standard physiotherapy (TENS, mobility exercises, and strengthening) Receives: Device: a percussion massage gun (Hypervolt device (Hyperice, CA, USA)); Other: conventional physiotherapy program |
| Vibration Therapy (33 Hz) Group | Experimental | Participants in this group will receive vibration therapy at 33 Hz using a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) in addition to a standard physiotherapy program. The therapy will target the deltoid, supraspinatus, infraspinatus, and teres minor muscles, applying vibration along the origin-insertion pathway.
Duration: 3 minutes per muscle Frequency: 3 times per week Total Treatment Period: 3 weeks Additional Treatment: Standard physiotherapy (TENS, mobility exercises, and strengthening) Receives: Device: a percussion massage gun (Hypervolt device (Hyperice, CA, USA)); Other: conventional physiotherapy program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of Joint Position Sense
The joint position sense of the participants in the study will be measured using the Fizyosoft Extremity ROM system. Joint position sense will be evaluated in 60-degree shoulder flexion and abduction movements.
Participants will be asked to lift their arm to 60 degrees with their eyes open and remember the position. Then, they will be instructed to replicate the same movement with their eyes closed. The shoulder angle will be measured while their eyes are closed.
The difference between the open-eye and closed-eye measurements will be recorded as the joint position sense. This method will be applied at 60-degree shoulder flexion and abduction .The average of two trials will consider for data evaluation.
Measured: 3 weeks
Secondary outcomes (4)
Visual Analogue Scale
Visual Analogue Scale (VAS) will be used to evaluate the pain intensity of patients. VAS consists of a 10 cm long horizontal line. '0' represents no pain, '10' represents unbearable pain. During our evaluation, patients will be asked to mark the level of pain they feel on this chart, and the distance to the starting point will be measured and recorded with the ruler.
Measured: 3 weeks
Range of Motion
The shoulder range of motion (ROM) of the participants included in the study will be measured using the Fizyosoft Extremity ROM system.
The measurements will be recorded as follows:
Flexion and abduction: 0-180 degrees Internal and external rotation: 0-90 degrees.
Measured: 3 weeks
Disabilities of the Arm, Shoulder, and Hand Questionnaire
The DASH questionnaire is used to assess physical disability and functionality in upper extremity injuries. It consists of three subcategories:
The first section contains 30 questions measuring functional and symptom scores, including:
21 questions evaluating daily living activities, 5 questions assessing symptoms (pain, activity-related pain, tingling, weakness, and movement restriction), 4 questions related to social function, work, sleep, and self-confidence. The work module consists of 4 additional questions, evaluating the participant's ability to perform work-related tasks.
Each question is answered using a 5-point Likert scale:
- = No difficulty
- = Mild difficulty
- = Moderate difficulty
- = Severe difficulty
- = Unable to perform the activity A higher total score indicates a greater level of disability.
Measured: 3 weeks
Assessment of Quality of Life
The Rotator Cuff Quality of Life (RC-QoL) questionnaire was developed by Hollishead et al. and was validated for the Turkish population by Çınar-Medeni et al. in 2015. This questionnaire is a specific assessment tool designed to evaluate the quality of life in individuals with rotator cuff pathology.
The scale consists of 34 questions categorized into five sections:
Physical symptoms Work-related activities Daily living activities Social aspects Emotional well-being
Each question is scored on a scale from 0 to 100, where:
0 = Severe pain or impairment 100 = No pain or impairment A higher score indicates better quality of life. The total score is calculated by summing the scores of the answered questions, dividing by the number of answered questions, and converting the result into a percentage.
Measured: 3 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Mar 2025
- Study start25 Mar 2025
- Primary completion25 Jun 2025
- Study completion20 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Rotator Cuff SyndromeStudies of the same condition, open and under way.
- More trials run by Medipol UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Parallel Assignment
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Medipol University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Emre DANSUK, Medipol University
- Investigators
- Emre Dansuk, PhD, Principal investigator, Medipol University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06899945
- Sponsor's protocol ID
- E-10840098-202.3.02-1958
- Status last verified
- Aug 2025
- First submitted
- 21 Mar 2025
- Last updated
- 29 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Dansuk E, Menek B, Erayata BN, Menek MY. Effects of different frequencies of percussion massage therapy on pain, range of motion, functionality, joint position sense, and quality of life in individuals with rotator cuff tears: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2026 Apr 1;18(1):167. doi: 10.1186/s13102-026-01581-4.
PubMed 41918014
Study at a glance
From the registry record, last updated by the sponsor on 29 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Vibration Therapy at Different Frequencies on Pain, Range of Motion, Functionality, Joint Position Sense, and Quality of Life in Individuals With Rotator Cuff Syndrome
- ClinicalTrials.gov ID
- NCT06899945
- Acronym / sponsor ID
- E-10840098-202.3.02-1958
- Conditions
- Rotator Cuff Syndrome, Vibration Therapy
- Keywords
- Rotator Cuff Syndrome, Vibration Therapy, Pain, Functionality, Proprioception, Quality of life
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Medipol UniversityUniversity, hospital or other
- Study start
- 25 Mar 2025 (actual)
- Primary completion
- 25 Jun 2025 (actual)
- Study completion
- 20 Jul 2025 (actual)
- First posted
- 28 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the effects of vibration therapy applied at different frequencies using a percussion massage gun on pain, range of motion (ROM), functionality, joint position sense, and quality of life in individuals with rotator cuff syndrome.
Rotator cuff syndrome is a common shoulder disorder caused by excessive use, muscle weakness, trauma, or instability, leading to pain, restricted movement, and reduced functional capacity. Although percussion massage therapy has gained popularity for its potential therapeutic benefits, there is limited scientific evidence on its effectiveness in improving ROM, pain reduction, and functional outcomes.
A total of 48 participants diagnosed with rotator cuff lesions will be included in the study and divided into three groups:
Vibration Group (33 Hz) Vibration Group (16.7 Hz) Control Group (Conventional Physiotherapy)
The intervention will include:
Conventional physiotherapy exercises applied to all groups, Vibration therapy with a percussion massage gun applied to the experimental groups, targeting the deltoid, supraspinatus, infraspinatus, and teres minor muscles for three minutes per muscle, three times per week for three weeks.
Outcome Measures:
Pain: Visual Analog Scale (VAS) ROM \& Joint Position Sense: Measured using the Goniometer Pro mobile application Functionality: Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire Quality of Life: Rotator Cuff Quality of Life (RC-QoL) questionnaire
Hypotheses:
Vibration therapy at different frequencies will significantly impact pain, ROM, functionality, joint position sense, and quality of life.
33 Hz vibration therapy will be more effective than 16.7 Hz in improving outcomes.
The data will be analyzed using SPSS 25, with statistical tests applied based on data distribution. This research aims to contribute to the understanding of vibration therapy's role in managing rotator cuff syndrome and its effectiveness in clinical rehabilitation.
Detailed description
Rotator cuff syndrome is a common shoulder disorder caused by excessive use, muscle weakness, trauma, or instability. It often results in pain, restricted movement, and reduced functional capacity. The condition is associated with subacromial space compression, leading to tendinitis, partial tears, or full rupture, which affects daily activities and overall quality of life.
Percussion massage therapy is an emerging treatment method that combines elements of traditional massage and vibration therapy. Introduced in the 1950s by Robert Fulford, it was later developed into handheld devices for self-administered and professional use. Percussion therapy is believed to reduce pain, enhance circulation, improve tissue healing, decrease muscle spasms, and increase joint range of motion (ROM).
However, scientific evidence regarding its effectiveness, particularly in rotator cuff syndrome, remains limited. This study aims to investigate the effects of different frequencies of vibration therapy applied with a percussion massage gun on pain, ROM, functionality, joint position sense, and quality of life in individuals with rotator cuff syndrome.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
- Model description
- Parallel Assignment
| Arm | Type | Receives |
|---|---|---|
| Control Group (Conventional Physiotherapy) | Active comparator | Other: conventional physiotherapy programParticipants in the control group will receive only conventional physiotherapy without vibration therapy. This ensures a baseline comparison to assess the effectiveness of vibration therapy. Treatment Modalities: TENS therapy (20 minutes, 100 Hz) Mobility exercises (wand exercises, Codman exercises, active/passive stretching) Strengthening exercises (theraband-based training) Frequency: 5 sessions per week Total Treatment Period: 3 weeks |
| Vibration Therapy (16.7 Hz) Group | Experimental | Device: a percussion massage gun (Hypervolt device (Hyperice, CA, USA)), Other: conventional physiotherapy programThis group will receive vibration therapy at 16.7 Hz using a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) along with a standard physiotherapy program. The treatment protocol mirrors the 33 Hz group, except for the vibration frequency. Duration: 3 minutes per muscle Frequency: 3 times per week Total Treatment Period: 3 weeks Additional Treatment: Standard physiotherapy (TENS, mobility exercises, and strengthening) |
| Vibration Therapy (33 Hz) Group | Experimental | Device: a percussion massage gun (Hypervolt device (Hyperice, CA, USA)), Other: conventional physiotherapy programParticipants in this group will receive vibration therapy at 33 Hz using a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) in addition to a standard physiotherapy program. The therapy will target the deltoid, supraspinatus, infraspinatus, and teres minor muscles, applying vibration along the origin-insertion pathway. Duration: 3 minutes per muscle Frequency: 3 times per week Total Treatment Period: 3 weeks Additional Treatment: Standard physiotherapy (TENS, mobility exercises, and strengthening) |
Who may qualify
- Ages
- 30 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Individuals diagnosed with rotator cuff lesion,
- Experiencing shoulder pain for at least 3 weeks,
- Aged between 30-60 years,
- Having restricted shoulder range of motion.
Key exclusion criteria (4 listed)
- Individuals with an additional orthopedic or neurological disorder affecting the shoulder,
- Those with a history of previous shoulder trauma,
- Individuals who have participated in a physiotherapy program within the last 3 months,
- Those unable to tolerate vibration therapy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| a percussion massage gun (Hypervolt device (Hyperice, CA, USA))Vibration application will be applied to the individuals in this group in addition to conventional methods. Vibration application will be applied to the deltoid, supraspinatus, infraspinatus, and teres minor muscles with a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) along the origo-insertio line for 3 minutes for each muscle group. Vibration application will be performed using the soft head of the percussion massage gun. Vibration therapy will be applied 3 days a week for 3 weeks. | Device | Vibration Therapy (16.7 Hz) Group, Vibration Therapy (33 Hz) Group |
| conventional physiotherapy programParticipants in the conventional physiotherapy program will follow a 3-week exercise plan, with sessions 5 days per week, each lasting 30 minutes under physiotherapist supervision. Treatment includes: TENS therapy (20 min, 100 Hz) on the painful area. Wand exercises for flexion, abduction, extension, internal, and external rotation (10 reps/set). Codman exercises for flexion, abduction, and circular movements (10 reps/set). Active \& passive stretching for flexion, abduction, internal, and external rotation (10 reps/set). Finger ladder exercises for flexion and abduction (10 reps/set). Strengthening with a theraband for flexion, abduction, external/internal rotation, and extension, adjusted based on progress (10 reps/set). This exercise program will be applied to all study groups. | Other | Control Group (Conventional Physiotherapy), Vibration Therapy (16.7 Hz) Group, Vibration Therapy (33 Hz) Group |
Primary outcome
Evaluation of Joint Position Sense
Time frame: 3 weeks
The joint position sense of the participants in the study will be measured using the Fizyosoft Extremity ROM system. Joint position sense will be evaluated in 60-degree shoulder flexion and abduction movements. Participants will be asked to lift their arm to 60 degrees with their eyes open and remember the position. Then, they will be instructed to replicate the same movement with their eyes closed. The shoulder angle will be measured while their eyes are closed. The difference between the open-eye and closed-eye measurements will be recorded as the joint position sense. This method will be applied at 60-degree shoulder flexion and abduction .The average of two trials will consider for data evaluation.
4 secondary outcomes
Visual Analogue Scale
Time frame: 3 weeks
Range of Motion
Time frame: 3 weeks
Disabilities of the Arm, Shoulder, and Hand Questionnaire
Time frame: 3 weeks
Assessment of Quality of Life
Time frame: 3 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Aug 2025.
- Derived from this study: PubMed 41918014Dansuk E, Menek B, Erayata BN, Menek MY. Effects of different frequencies of percussion massage therapy on pain, range of motion, functionality, joint position sense, and quality of life in individuals with rotator cuff tears: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2026 Apr 1;18(1):167. doi: 10.1186/s13102-026-01581-4.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Emre Dansuk, PhD principal investigator
Medipol University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing a percussion massage gun (Hypervolt device (Hyperice, CA, USA)) and conventional physiotherapy program in people with Rotator Cuff Syndrome and Vibration Therapy, run by Medipol University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of Joint Position Sense (time frame: 3 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06899945, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Aug 2025.