Long QT SyndromeNCT06887387
Wearable Devices for Patient Monitoring in Long QT Syndrome
An observational study of Long QT Syndrome, run by Queen Mary University of London at 1 site in United Kingdom.
Trial summary
The main research question of this study is whether wearable devices have utility in monitoring patients with Long QT syndrome. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Long QT Syndrome
- What is being tested?
- Wearable device
- Type of treatment
- Medical device
- How many people
- 80 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 1 Apr 2025to 4 Sep 2026
- How long will I take part?
- 3 Months
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with a diagnosis of long QT syndrome
Who may be able to join
- Clinical diagnosis of Long QT Syndrome
- Aged 18 years or over
- Phone with iOS version 15 or Android OS 9.0 or higher
- Able and willing to provide informed consent
Who cannot join
- Unwilling or unable to give consent
- Ventricular pacing at recruitment
- Bundle branch block or pre-excitation at baseline
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site, 1 recruiting
- Recruiting
Barts and London Hospital NHS Trust
London
William Young, 07872533176, w.young@qmul.ac.uk
William Young
About this study
Official title: Application of Wearable Devices for Remote QT Interval Monitoring and Symptom Investigation for Patients With Long QT Syndrome
The main research question of this study is whether wearable devices have utility in monitoring patients with Long QT syndrome.
- Conditions
- Long QT Syndrome
- Being tested
- Wearable device
- Medical subject headings
- Long QT Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Wearable deviceDevice
This is an observational study that does not impact routine clinical care for participants
What is being measured
The primary outcome is the main question the study is designed to answer.
1. Determine the accuracy of repeated QT interval measurements using Fitbit-derived ECGs in patients with Long QT syndrome compared with the current standard (12-lead ECG and ambulatory monitors)
Measured: From enrollment to 3 months
2. Establish intra-patient QT variability from weekly Fitbit-ECGs and frequency of measurements over 500ms.
Measured: From enrollment to 3 months
Secondary outcomes (2)
1. Establish the utility of wearable devices for determining symptom aetiology in LQTS.
Measured: From enrollment to 3 months
2. Develop pipelines for the analysis of ECG data collected remotely including use of in-house QT automated algorithms for future machine learning applications.
Measured: From enrollment to 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Mar 2025
- Study start1 Apr 2025
- Primary completion4 Sep 2026 (estimated)
- Study completion4 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Long QT SyndromeStudies of the same condition, open and under way.
- More trials run by Queen Mary University of LondonThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 80 participants (estimated)
- Target duration
- 3 Months
Sponsor and investigators
- Lead sponsor
- Queen Mary University of London
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- William J Young, MBBS, PhD, Principal investigator, Queen Mary University of London and St Bartholomew's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06887387
- Sponsor's protocol ID
- 173178
- Status last verified
- May 2026
- First submitted
- 14 Mar 2025
- Last updated
- 19 May 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Application of Wearable Devices for Remote QT Interval Monitoring and Symptom Investigation for Patients With Long QT Syndrome
- ClinicalTrials.gov ID
- NCT06887387
- Acronym / sponsor ID
- 173178
- Conditions
- Long QT Syndrome
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Queen Mary University of LondonUniversity, hospital or other
- Study start
- 1 Apr 2025 (actual)
- Primary completion
- 4 Sep 2026 (estimated)
- Study completion
- 4 Sep 2026 (estimated)
- First posted
- 20 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main research question of this study is whether wearable devices have utility in monitoring patients with Long QT syndrome.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 3 Months
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with a diagnosis of long QT syndrome
Key inclusion criteria (4 listed)
- Clinical diagnosis of Long QT Syndrome
- Aged 18 years or over
- Phone with iOS version 15 or Android OS 9.0 or higher
- Able and willing to provide informed consent
Key exclusion criteria (3 listed)
- Unwilling or unable to give consent
- Ventricular pacing at recruitment
- Bundle branch block or pre-excitation at baseline
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Wearable deviceThis is an observational study that does not impact routine clinical care for participants | Device | – |
Primary outcome
1. Determine the accuracy of repeated QT interval measurements using Fitbit-derived ECGs in patients with Long QT syndrome compared with the current standard (12-lead ECG and ambulatory monitors)
Time frame: From enrollment to 3 months
2. Establish intra-patient QT variability from weekly Fitbit-ECGs and frequency of measurements over 500ms.
Time frame: From enrollment to 3 months
2 secondary outcomes
1. Establish the utility of wearable devices for determining symptom aetiology in LQTS.
Time frame: From enrollment to 3 months
2. Develop pipelines for the analysis of ECG data collected remotely including use of in-house QT automated algorithms for future machine learning applications.
Time frame: From enrollment to 3 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
William J Young, MBBS, PhD principal investigator
Queen Mary University of London and St Bartholomew's Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Long QT Syndrome, run by Queen Mary University of London at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
1. Determine the accuracy of repeated QT interval measurements using Fitbit-derived ECGs in patients with Long QT syndrome compared with the current standard (12-lead ECG and ambulatory monitors) (time frame: From enrollment to 3 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 May 2026.