Substance UseNCT06875323
FostrSpace-CASA R61/R33
A study testing ECHO-FostrSpace and Informational Session in people with Substance Use, run by University of California, San Francisco at 1 site in United States.
Trial summary
The purpose of this study is to understand how an online digital health application (app) called FostrSpace can reduce substance use among youth (ages 13-20 years old) in foster care. Read more about this study
- Who is it for?
- Ages 13 to 20 yearsHealthy volunteers can take part
- Conditions the study is for
- Substance Use
- What is being tested?
- ECHO-FostrSpace and Informational Session
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 400 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Mar 2024to 1 Mar 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 20 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Adolescents and young adults will be eligible if they are age 13-20, are proficient in English, have an assigned CASA worker, and have a device with web access.
- CASAs (ages 18 and over) will be eligible if they are assigned to a youth between the ages of 13- 20.
Who cannot join
- Youth: Exclusion criteria include being non-English speaking, being within 3 months of ending with CASA services, cognitive impairment that precludes ability to provide informed consent.
- CASA: Exclusion criteria include being non-English speaking and working with a youth who is within 3 months of ending with CASA services.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
UCSF Zuckerberg San Francisco General Hospital
San Francisco, California, 94131
About this study
Official title: CASA and FostrSpace: Systems Delivery of Digital Substance Use Prevention Tools to Foster Youth
The purpose of this study is to understand how an online digital health application (app) called FostrSpace can reduce substance use among youth (ages 13-20 years old) in foster care.
Read the detailed description
The goal of this clinical trial is to identify gaps in substance use prevention across existing CASA trainings and the FostrSpace app for foster youth and test how substance use trainings for CASA volunteers could help facilitate FostrSace app referrals to reduce and prevent substance use among CASA youth.
- Conditions
- Substance Use
- Being tested
- ECHO-FostrSpace, Informational Session
- Keywords
- Foster youth, Substance use, mHealth
- Medical subject headings
- Substance-Related Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ECHO-FostrSpaceOther
Six ECHO-FostrSpace session training for CASA volunteers.
Informational SessionOther
One ECHO-FostrSpace session training for CASA volunteers.
| Study group | Role | What they receive |
|---|---|---|
| InfoECHO | Experimental | CASA volunteers will attend a six 90-minute/biweekly co-occurring SU and trauma ECHO trainings. Receives: Other: ECHO-FostrSpace |
| InfoOnly | Other | CASA volunteers will attend a one-time 30-60 minute co-occurring SU and trauma ECHO training. Receives: Other: Informational Session |
What is being measured
The primary outcome is the main question the study is designed to answer.
Rate of Drug Use
The Texas Christian University (TCU) drug screen with opioid supplement is used to gather detailed information about drug and opioid use.
Measured: baseline
Rate of Cigarette Use
The Cigarette smoking and vaping/e-cigarette use is used to gather detailed information about nicotine and/or cannabis use.
Measured: baseline
Secondary outcomes (4)
The Alcohol and Marijuana Expectancy Questionnaire
The Alcohol and Marijuana Expectancy questionnaire is used to measure positive and negative expectancies about affective, cognitive and behavioral effects of alcohol and cannabis use. Items are rated from 1-5 scale and higher scores indicate negative alcohol and marijuana expectancies.
Measured: baseline
The Brief Young Adult Alcohol Consequences Questionnaire
The Brief Young Adult Alcohol Consequences Questionnaire is used to assess the severity of alcohol consumption. Higher scores indicate greater severity of consequences associated with alcohol consumption.
Measured: baseline
The Brief Marijuana Consequences Questionnaire
The Brief Marijuana Consequences Questionnaire is used to assess the severity of marijuana consumption. Higher scores indicate greater severity of consequences associated with marijuana consumption.
Measured: baseline
The Brief Symptom Inventory
Brief Symptom Inventory is used to measure depression, anxiety and somatization symptoms to assess for psychiatry distress. Index ranging from 0 to 72 with cut-score of 11 as indication of psychiatric distress.
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Mar 2025
- Study start1 Mar 2024
- Primary completion1 Mar 2029 (estimated)
- Study completion1 Mar 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Substance UseStudies of the same condition, open and under way.
- More trials run by University of California, San FranciscoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of California, San Francisco
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Sponsor
- Investigators
- Marina Tolou-Shams, PhD, Principal investigator, University of California, San Francisco
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06875323
- Sponsor's protocol ID
- 1R61DA059860-01
- Other IDs
- R61DA059860
- Status last verified
- Jul 2026
- First submitted
- 16 Dec 2024
- Last updated
- 29 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- CASA and FostrSpace: Systems Delivery of Digital Substance Use Prevention Tools to Foster Youth
- ClinicalTrials.gov ID
- NCT06875323
- Acronym / sponsor ID
- 1R61DA059860-01
- Conditions
- Substance Use
- Keywords
- Foster youth, Substance use, mHealth
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- University of California, San FranciscoUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- 1 Mar 2024 (actual)
- Primary completion
- 1 Mar 2029 (estimated)
- Study completion
- 1 Mar 2029 (estimated)
- First posted
- 13 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to understand how an online digital health application (app) called FostrSpace can reduce substance use among youth (ages 13-20 years old) in foster care.
Detailed description
The goal of this clinical trial is to identify gaps in substance use prevention across existing CASA trainings and the FostrSpace app for foster youth and test how substance use trainings for CASA volunteers could help facilitate FostrSace app referrals to reduce and prevent substance use among CASA youth.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| InfoECHO | Experimental | Other: ECHO-FostrSpaceCASA volunteers will attend a six 90-minute/biweekly co-occurring SU and trauma ECHO trainings. |
| InfoOnly | Other | Other: Informational SessionCASA volunteers will attend a one-time 30-60 minute co-occurring SU and trauma ECHO training. |
Who may qualify
- Ages
- 13 to 20 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (2 listed)
- Adolescents and young adults will be eligible if they are age 13-20, are proficient in English, have an assigned CASA worker, and have a device with web access.
- CASAs (ages 18 and over) will be eligible if they are assigned to a youth between the ages of 13- 20.
Key exclusion criteria (2 listed)
- Youth: Exclusion criteria include being non-English speaking, being within 3 months of ending with CASA services, cognitive impairment that precludes ability to provide informed consent.
- CASA: Exclusion criteria include being non-English speaking and working with a youth who is within 3 months of ending with CASA services.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ECHO-FostrSpaceSix ECHO-FostrSpace session training for CASA volunteers. | Other | InfoECHO |
| Informational SessionOne ECHO-FostrSpace session training for CASA volunteers. | Other | InfoOnly |
Primary outcome
Rate of Drug Use
Time frame: baseline
The Texas Christian University (TCU) drug screen with opioid supplement is used to gather detailed information about drug and opioid use.
Rate of Cigarette Use
Time frame: baseline
The Cigarette smoking and vaping/e-cigarette use is used to gather detailed information about nicotine and/or cannabis use.
4 secondary outcomes
The Alcohol and Marijuana Expectancy Questionnaire
Time frame: baseline
The Brief Young Adult Alcohol Consequences Questionnaire
Time frame: baseline
The Brief Marijuana Consequences Questionnaire
Time frame: baseline
The Brief Symptom Inventory
Time frame: baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Marina Tolou-Shams, PhD principal investigator
University of California, San Francisco
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ECHO-FostrSpace and Informational Session in people with Substance Use, run by University of California, San Francisco at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 29 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Rate of Drug Use (time frame: baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2026.