AzTrials
AzTrials

Cancer SurvivorshipSUCCESSNCT06869512

Cooperative Extension and Cancer Survivorship

A study testing SUCCESS in people with Cancer Survivorship, run by University of Oklahoma at 1 site in United States.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The goal of this clinical trial is to learn if a cancer survivor program, delivered via Cooperative Extension, is feasible and if it can improve health outcomes in cancer survivors who are post-active treatment. Aim 1: Evaluate the feasibility and acceptability of SUCCESS. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Cancer Survivorship
What is being tested?
SUCCESS
Could I receive a placebo?
No, everyone receives an active treatment
How many people
80 participants
Where
1 siteUnited States
Study dates
24 Feb 2025to 31 Dec 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Previous adult-diagnosed cancer
  • Post active cancer treatment
  • No current active treatment, hormonal therapy permitted
  • Ability to get to group sessions
  • In Oklahoma

Who cannot join

  • Current palliative or hospice care
  • Surgical or medical history that precludes participation
  • Positive screen on the Physical Activity Readiness Questionnaire+ (PAR-Q+) without a doctor's note approving study participation

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Ashlea C Braun, PhD contact

15672401582

ashlea-braun@ouhsc.edu

United States1 site, 1 recruiting

  • University of Oklahoma

    Tulsa, Oklahoma, 74135

    Ashlea C Braun, PhD, 567-240-1582, ashlea-braun@ouhsc.edu

    Recruiting

Other trials in United States

About this study

Official title: Cooperative Extension and Cancer Survivorship: Supportive Care Via Cooperative Extension Services (SUCCESS)

The goal of this clinical trial is to learn if a cancer survivor program, delivered via Cooperative Extension, is feasible and if it can improve health outcomes in cancer survivors who are post-active treatment.

Aim 1: Evaluate the feasibility and acceptability of SUCCESS. Hypothesis 1: SUCCESS will be feasible and acceptable as evidenced by delivery of the intervention among Educators (implementation), including in agreement with the curriculum in Phase 1 (fidelity) with >85% attendance (demand) among participants with >80% rating the intervention as acceptable or highly acceptable on 5-point Likert-type scale (acceptability).

Read more

Aim 2: Determine the preliminary efficacy of SUCCESS for improving HRQOL (primary outcome) and other psychosocial and health-related endpoints (e.g., financial toxicity) (secondary outcomes). Hypothesis 2: Compared to matched controls, adults LWBC who complete SUCCESS will have significant improvements in HRQOL per the PROMIS Global Health v1.2 at follow-up (i.e., after 6 weeks).

Aim 3: Examine changes in conserved transcriptional response to adversity (CTRA) gene expression in a subset of interventions participants at follow-up. Hypothesis 3: Adults LWBC who complete SUCCESS will experience significant CTRA down-regulation.

This is a single arm trial and there is no comparison group.

Participants will be asked to do survey- and Zoom-based data collection before and after completing the 6-week program.

Being tested
SUCCESS

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • SUCCESSBehavioural

    6 group-based sessions with 25 minutes of didactic content, 25 minutes of facilitated support group, and 10 minutes of group physical activity

Study groups in NCT06869512
Study groupRoleWhat they receive
SUCCESS ProgramExperimentalThis includes our cancer survivorship program which entails 6 weekly group education sessions. Each session includes 25 minutes of didactic and discussion-based lecture, 25 minutes of facilitated support group, and 10 minutes of brief group-based exercise.
Receives: Behavioral: SUCCESS

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Delivery of sessions

    We will measure the percent of SUCCESS sessions delivered as planned by Educators

    Measured: Once per week for six weeks

  2. Fidelity to SUCCESS protocol

    We will measure what percentage of planned SUCCESS content is delivered as instructed.

    Measured: Once per week for six weeks

  3. Participant attendance

    We will measure how many enrolled participants attend each SUCCESS session

    Measured: Once per week for six weeks

  4. Acceptability of SUCCESS

    We will administer a feasibility survey after SUCCESS for participants to rate how much they liked it. Rating will be on a 5-point Likert Scale ("How would you rate this program?" 1=poor, 5=excellent)

    Measured: Measured after SUCCESS (week 7-8 of the clinical trial)

Secondary outcomes (14)

  1. Diet quality

    We will measure diet quality as assessed via the National Cancer Institute Dietary Screener Questionnaire (DSQ). Outputs from the DSQ are intake of fruits and vegetables (cup equivalents), dairy (cup equivalents), added sugars (teaspoon equivalents), whole grains (ounce equivalents), fiber (g), and calcium (mg).

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  2. Physical function

    We will measure physical function using the 30-second Timed Chair Rise (30sTCR), measured in seconds.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  3. Depressive symptoms

    Depressive symptoms will be measured using the Patient Health Questionnaire (PHQ-9). This provides a numeric score from 0-27, with higher=more depression

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  4. Anxiety symptoms

    Anxiety symptoms will be measured using the General Anxiety Disorder-7 (GAD-7). This provides a numeric score from 0-21, with higher=more anxiety.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  5. Loneliness

    Loneliness will be measuring using the UCLA Loneliness Scale. This provides a numeric score from 20-80, with higher=more loneliness.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  6. Social isolation

    Social isolation will be measured using the PROMIS Social Isolation Short Form (SF). This provides a numeric score from 4-20, with higher scores indicating more social isolation.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  7. Financial Toxicity

    Financial toxicity will be measured using the COST: A FACIT Measure of Financial Toxicity (FACIT-COST). The FACT-COST provides a numeric score from 0-44, with higher meaning better financial well-being.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  8. Health-related quality of life

    Health-related quality of life (HRQOL) will be measured using the PROMIS Global Health v1.2, which yields Global Physical Health and Global Mental Health Scores, both of which range numerically from 4-20; higher indicates better HRQOL.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  9. Food insecurity

    Food insecurity will be measured using the USDA 6-item food insecurity screener. This yields a numeric score from 0-6, with higher=more food insecurity,

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  10. Basic psychological needs

    Basic psychological needs according to Self-Determination Theory (autonomy, competence, relatedness) will be measured using the Basic Psychological Need Satisfaction Scale. This provides three scores (one per psychological need) that ranges from 1-7, with higher=more of that need met.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  11. Self-reported pain

    Pain will be measured using the Pain, Enjoyment, and General Activity (PEG) scale which provides a numeric score from 0-10, with 10=more pain and more interference from pain.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  12. Conserved Transcriptional Response to Adversity (CTRA) gene expression

    Remote blood sampling procedures will be used to collect blood spots. RNA will be extracted from spots and sequenced for quantification of the 53-gene contrast score that comprises CTRA. This will only be done in a subset of participants.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  13. Physical function

    We will measure physical function using 5 Times Sit-to-Stand (5xSTS) tests, measured in seconds.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

  14. Financial Toxicity

    Financial toxicity will be measured using the Composite Financial Burden Score (CFBS). The CFBS provides a numeric score from 0-6; higher scores denote increased financial burden.

    Measured: Baseline (week 1) and post-SUCCESS (week 7-8)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted11 Mar 2025
  2. Study start24 Feb 2025
  3. Primary completion31 Dec 2026 (estimated)
  4. Study completion31 Dec 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrolment
80 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06869512
Sponsor's protocol ID
17371
Acronym
SUCCESS
Status last verified
Jun 2025
First submitted
7 Feb 2025
Last updated
26 Jun 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: Will be made available upon request.

Publications

  • Pitasi O, Hildebrand D, Liebe R, Joyce J, Nagykaldi Z, Robertson MC, Braun A. Hiding in plain sight: Cooperative Extension as an underutilized approach to improving cancer survivorship outcomes in underserved populations. J Cancer Surviv. 2026 Apr;20(2):792-803. doi: 10.1007/s11764-024-01687-z. Epub 2024 Oct 10.

    PubMed 39388009

Questions about this trial

What is this clinical trial studying?

A study testing SUCCESS in people with Cancer Survivorship, run by University of Oklahoma at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 26 Jun 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Ashlea C Braun, PhD (15672401582, ashlea-braun@ouhsc.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Delivery of sessions (time frame: Once per week for six weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06869512, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2025.

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