Hidradenitis Suppurativa (HS)Phase 3STOP-LTRNCT06855498
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
A Phase 3 study testing povorcitinib in people with Hidradenitis Suppurativa (HS), run by Incyte Corporation at 296 sites in 20 countries.
Trial summary
Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hidradenitis Suppurativa (HS)
- What is being tested?
- povorcitinib
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 600 participants
- Where
- 296 sitesin 20 countries
- Study dates
- 28 Feb 2025to 28 Feb 2028
- Phase
- Phase 3
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Ability to comprehend and willingness to sign a written ICF for the study.
- Completed the treatment period of a predetermined, Incyte-sponsored, povorcitinib parent study without safety or tolerability concerns, per investigator's assessment.
- Received clinical benefit from treatment with study drug during the parent study, as determined by the investigator.
- Demonstrated compliance, as assessed by the investigator, with the parent Protocol requirements.
- Willingness to avoid pregnancy or fathering children as defined in the protocol.
- Willingness and ability to comply with the study Protocol and procedures.
Who cannot join
- Had been permanently discontinued from study treatment during the parent study.
- Had temporary study drug interruption due to safety and/or efficacy reasons at or after the final visit of the parent study.
- Received at least 1 dose of either of the following therapies within the 28 days prior to starting treatment in this rollover study:
- Biologic immunomodulator (examples include but are not limited to adalimumab, bimekizumab, dupilumab, infliximab, nemolizumab, secukinumab).
- Live, attenuated vaccine.
- Plans for administration of a live, attenuated vaccine during this study or within 8 weeks after the last dose of study drug.
Show all 11Show fewer
- Women who are pregnant (or who are considering pregnancy) or breastfeeding.
- Known hypersensitivity or severe reaction to povorcitinib or excipients of povorcitinib and/or other products in the same class.
- Currently enrolled in any other clinical study involving an investigational product or any other type of medical research judged not to be scientifically or medically compatible with this study.
- Any condition that would, in the investigator's and/or sponsor's judgment, interfere with full participation in the study, including administration of study drug and attending required study visits; pose a significant risk to the participant; or interfere with interpretation of study data.
- Other protocol-defined Inclusion/Exclusion Criteria may apply.
Trial locations and contacts
296 sites in 20 countries. Contact the study team or a site near you to ask about taking part.
296 sites in 20 countries
United States86 sites, 86 recruiting
- Not yet recruiting
Investigative Site US118
Albuquerque, New Mexico, 87131
- Recruiting
Investigative Site US061
Ann Arbor, Michigan, 48103
- Recruiting
Investigative Site US038
Baltimore, Maryland, 21287-0876
- Recruiting
Investigative Site US012
Baton Rouge, Louisiana, 70809
- Recruiting
Investigative Site US021
Bellaire, Texas, 77401
- Recruiting
Investigative Site US028
Bexley, Ohio, 43209
- Not yet recruiting
Investigative Site US106
Birmingham, Alabama, 35233
- Recruiting
Investigative Site US086
Birmingham, Alabama, 35244
- Recruiting
Investigative Site US002
Boca Raton, Florida, 33486
- Recruiting
Investigative Site US030
Boston, Massachusetts, 02215
- Recruiting
Investigative Site US048
Brighton, Massachusetts, 02135
- Recruiting
Investigative Site US031
Chapel Hill, North Carolina, 27516
- Recruiting
Investigative Site US125
Chicago, Illinois, 60602
- Recruiting
Investigative Site US093
Chicago, Illinois, 60657
- Recruiting
Investigative Site US025
Cincinnati, Ohio, 45219
- Recruiting
Investigative Site US073
Columbus, Ohio, 43215
- Recruiting
Investigative Site US084
Coral Gables, Florida, 33146
- Recruiting
Investigative Site US102
Cumming, Georgia, 30040
- Recruiting
Investigative Site US078
Dallas, Texas, 75230
- Recruiting
Investigative Site US010
Dallas, Texas, 75246
- Not yet recruiting
Investigative Site US120
Detroit, Michigan, 48202
- Recruiting
Investigative Site US117
Dublin, Ohio, 43016
- Recruiting
Investigative Site US082
East Syracuse, New York, 13057
- Recruiting
Investigative Site US076
Fountain Valley, California, 92708-3701
- Recruiting
Investigative Site US077
Fremont, California, 94538
- Recruiting
Investigative Site US017
Hialeah, Florida, 33012
- Recruiting
Investigative Site US019
Hollywood, Florida, 33021-6746
- Recruiting
Investigative Site US071
Huntington Beach, California, 92647
- Not yet recruiting
Investigative Site US108
Indianapolis, Indiana, 46202
- Recruiting
Investigative Site US008
Indianapolis, Indiana, 46250
- Recruiting
Investigative Site US097
Irvine, California, 92697
- Recruiting
Investigative Site US020
Laguna Niguel, California, 92677
- Recruiting
Investigative Site US036
Los Angeles, California, 90033
- Not yet recruiting
Investigative Site US095
Los Angeles, California, 90036
- Recruiting
Investigative Site US067
Los Angeles, California, 90045
- Recruiting
Investigative Site US051
Marietta, Georgia, 30060-1047
- Recruiting
Investigative Site US062
Miami, Florida, 33126
- Recruiting
Investigative Site US015
Miami, Florida, 33136
- Recruiting
Investigative Site US059
Miami, Florida, 33173
- Recruiting
Investigative Site US072
Miami Lakes, Florida, 33014
- Recruiting
Investigative Site US079
Miami Lakes, Florida, 33014
- Not yet recruiting
Investigative Site US132
Mill Creek, Washington, 98012
- Recruiting
Investigative Site US011
Minneapolis, Minnesota, 55455
- Recruiting
Investigative Site US098
Montgomery, Alabama, 36117
- Recruiting
Investigative Site US057
New Orleans, Louisiana, 70115
- Recruiting
Investigative Site US034
New York, New York, 10028-3135
- Recruiting
Investigative Site US081
New York, New York, 10075
- Recruiting
Investigative Site US065
New York, New York, 10128
- Recruiting
Investigative Site US075
New York, New York, 10956
- Recruiting
Investigative Site US027
Norfolk, Virginia, 23502
- Recruiting
Investigative Site US023
North Miami Beach, Florida, 33162
- Recruiting
Investigative Site US060
Northridge, California, 91325
- Recruiting
Investigative Site US037
Oakland, California, 94611
- Recruiting
Investigative Site US029
Ocala, Florida, 34470
- Recruiting
Investigative Site US085
Oklahoma City, Oklahoma, 73170
- Recruiting
Investigative Site US074
Philadelphia, Pennsylvania, 19103
- Recruiting
Investigative Site US004
Phoenix, Arizona, 85006
- Not yet recruiting
Investigative Site US109
Plano, Texas, 75024
- Recruiting
Investigative Site US069
Plymouth Meeting, Pennsylvania, 19462
- Recruiting
Investigative Site US007
Portsmouth, New Hampshire, 03801
- Recruiting
Investigative Site US094
Richmond, Virginia, 23226
- Recruiting
Investigative Site US050
Rochester, New York, 14642
- Recruiting
Investigative Site US101
Rockville, Maryland, 20850
- Recruiting
Investigative Site US088
Saint Joseph, Missouri, 64506
- Recruiting
Investigative Site US083
San Antonio, Texas, 78218
- Not yet recruiting
Investigative Site US103
Sandy Springs, Georgia, 30328
- Recruiting
Investigative Site US089
Santa Monica, California, 90403
- Not yet recruiting
Investigative Site US092
Seattle, Washington, 98168
- Recruiting
Investigative Site US080
Sherman Oaks, California, 91403
- Recruiting
Investigative Site US063
South Jordan, Utah, 84095
- Recruiting
Investigative Site US003
Spokane, Washington, 99202
- Recruiting
Investigative Site US016
St Louis, Missouri, 63110
- Recruiting
Investigative Site US100
Stonecrest, Georgia, 30038
- Not yet recruiting
Investigative Site US104
Sunnyvale, California, 94086
- Recruiting
Investigative Site US035
Tampa, Florida, 33607
- Not yet recruiting
Investigative Site US133
Tampa, Florida, 33607
- Recruiting
Investigative Site US005
Tampa, Florida, 33613
- Recruiting
Investigative Site US001
Tampa, Florida, 33615
- Recruiting
Investigative Site US091
Troy, Michigan, 48084
- Not yet recruiting
Investigative Site US115
Tucson, Arizona, 85718
- Recruiting
Investigative Site US042
Waterford, Michigan, 48328
- Recruiting
Investigative Site US068
Webster, Texas, 77598
- Recruiting
Investigative Site US039
West Dundee, Illinois, 60118
- Recruiting
Investigative Site US064
West Lafayette, Indiana, 47906
- Recruiting
Investigative Site US066
West Palm Beach, Florida, 33401
- Recruiting
Investigative Site US070
West Palm Beach, Florida, 33401
Poland43 sites, 43 recruiting
- Recruiting
Investigative Site PL032
Bialystok, 15-453
- Recruiting
Investigative Site PL019
Chorzów, 41-516
- Recruiting
Investigative Site PL013
Cracov, 30-348
- Recruiting
Investigative Site PL009
Gdansk, 80-280
- Not yet recruiting
Investigative Site PL038
Gdansk, 80-382
- Recruiting
Investigative Site PL042
Gdansk, 80-952
- Not yet recruiting
Investigative Site PL037
Gdynia, 81-537
- Recruiting
Investigative Site PL029
Grodzisk Mazowiecki
- Recruiting
Investigative Site PL011
Katowice, 40-568
- Recruiting
Investigative Site PL025
Katowice, 40-600
- Recruiting
Investigative Site PL034
Katowice, 40-611
- Not yet recruiting
Investigative Site PL033
Katowice, 40-648
- Recruiting
Investigative Site PL044
Krakow, 31-559
- Recruiting
Investigative Site PL036
Lodz, 90-302
- Recruiting
Investigative Site PL021
Lodz, 90-436
- Recruiting
Investigative Site PL031
Lublin, 20-406
- Recruiting
Investigative Site PL002
Lublin, 20-573
- Recruiting
Investigative Site PL045
Lublin, 20-607
- Recruiting
Investigative Site PL020
Osielsko, 86-031
- Recruiting
Investigative Site PL006
Ostrowiec Świętokrzyski, 27-400
- Recruiting
Investigative Site PL016
Poznan, 61731
- Recruiting
Investigative Site PL003
Rzeszów, 35-055
- Not yet recruiting
Investigative Site PL043
Skierniewice, 96-100
- Recruiting
Investigative Site PL028
Szczecin, 70-332
- Not yet recruiting
Investigative Site PL010
Tarnów, 33-100
- Not yet recruiting
Investigative Site PL030
Torun, 87-100
- Not yet recruiting
Investigative Site PL046
Warsaw, 00-124
- Recruiting
Investigative Site PL017
Warsaw, 01-142
- Recruiting
Investigative Site PL026
Warsaw, 01-817
- Recruiting
Investigative Site PL007
Warsaw, 02-507
- Recruiting
Investigative Site PL014
Warsaw, 02-625
- Recruiting
Investigative Site PL012
Warsaw, 02-661
- Recruiting
Investigative Site PL039
Warsaw, 02-672
- Recruiting
Investigative Site PL023
Warsaw, 02-677
- Recruiting
Investigative Site PL004
Warsaw, 02-692
- Recruiting
Investigative Site PL027
Warsaw, 02-953
- Recruiting
Investigative Site PL024
Warsaw, 03-291
- Recruiting
Investigative Site PL040
Wroclaw, 50-381
- Not yet recruiting
Investigative Site PL018
Wroclaw, 50-450
- Recruiting
Investigative Site PL001
Wroclaw, 50-566
- Recruiting
Investigative Site PL005
Wroclaw, 51-503
- Recruiting
Investigative Site PL015
Wroclaw, 52-416
- Recruiting
Investigative Site PL022
Wroclaw, 54-239
Germany31 sites, 31 recruiting
- Recruiting
Investigative Site DE036
Aachen, 52074
- Recruiting
Investigative Site DE025
Bad Bentheim, 48455
- Recruiting
Investigative Site DE005
Berlin, 10117
- Recruiting
Investigative Site DE026
Berlin, 10247
- Not yet recruiting
Investigative Site DE039
Berlin, 12203
- Recruiting
Investigative Site DE006
Bochum, 44791
- Not yet recruiting
Investigative Site DE037
Bonn, 53105
- Recruiting
Investigative Site DE024
Buxtehude, 21614
- Recruiting
Investigative Site DE013
Darmstadt, 64283
- Recruiting
Investigative Site DE019
Darmstadt, 64283
- Recruiting
Investigative Site DE027
Dortmund, 44137
- Recruiting
Investigative Site DE012
Dresden, 01307
- Recruiting
Investigative Site DE014
Düsseldorf, 40225
- Recruiting
Investigative Site DE009
Erlangen, 91054
- Recruiting
Investigative Site DE011
Frankfurt am Main, 60590
- Recruiting
Investigative Site DE010
Göttingen, 37075
- Recruiting
Investigative Site DE001
Hamburg, 20246
- Recruiting
Investigative Site DE002
Hanover, 30159
- Recruiting
Investigative Site DE017
Heidelberg, 69115
- Recruiting
Investigative Site DE003
Kiel, 24105
- Recruiting
Investigative Site DE033
Leipzig, 04103
- Recruiting
Investigative Site DE034
Lübeck, 23538
- Not yet recruiting
Investigative Site DE029
Magdeburg, 39104
- Recruiting
Investigative Site DE015
Mainz, 55128
- Not yet recruiting
Investigative Site DE020
Memmingen, 87700
- Recruiting
Investigative Site DE008
Merzig, 66663
- Recruiting
Investigative Site DE030
München, 80802
- Not yet recruiting
Investigative Site DE016
Münster, 48149
- Recruiting
Investigative Site DE028
Oldenburg, 26133
- Recruiting
Investigative Site DE031
Tübingen, 72076
- Recruiting
Investigative Site DE018
Witten, 58453
Canada23 sites, 23 recruiting
- Recruiting
Investigative Site CA004
Barrie, Ontario, L4M 7G1
- Recruiting
Investigative Site CA023
Calgary, Alberta, T2J 7E1
- Recruiting
Investigative Site CA008
Calgary, Alberta, T3E 0B2
- Recruiting
Investigative Site CA030
Cobourg, Ontario, K9A 0Z4
- Recruiting
Investigative Site CA005
Edmonton, Alberta, T6G 1C3
- Recruiting
Investigative Site CA025
London, Ontario, N6A 2C2
- Recruiting
Investigative Site CA002
London, Ontario, N6H 5L5
- Recruiting
Investigative Site CA022
Markham, Ontario, L3P 1X3
- Recruiting
Investigative Site CA016
Mississauga, Ontario, L4Y 4C5
- Recruiting
Investigative Site CA001
Peterborough, Ontario, K9J 5K2
- Recruiting
Investigative Site CA020
Québec, Quebec, G1V4X7
- Recruiting
Investigative Site CA026
Québec, Quebec, G1W 4R4
- Recruiting
Investigative Site CA010
Richmond Hill, Ontario, L4B 1L1
- Recruiting
Investigative Site CA015
Saskatoon, Saskatchewan, S7K 2C1
- Not yet recruiting
Investigative Site CA031
Sherwood Park, Alberta, T8H 0P1
- Recruiting
Investigative Site CA017
Toronto, Ontario, M2N 3A6
- Recruiting
Investigative Site CA018
Toronto, Ontario, M3H 5Y8
- Recruiting
Investigative Site CA021
Toronto, Ontario, M4W 2N4
- Recruiting
Investigative Site CA032
Toronto, Ontario, M5N 1A8
- Not yet recruiting
Investigative Site CA024
Vancouver, British Columbia, V5Z 4E8
- Not yet recruiting
Investigative Site CA029
Verdun, Quebec, H4G 3E7
- Recruiting
Investigative Site CA019
Waterloo, Ontario, N2J 1C4
- Recruiting
Investigative Site CA003
Winnipeg, Manitoba, R3M 3Z4
Spain17 sites, 17 recruiting
- Recruiting
Investigative Site ES019
Alcorcón, 28922
- Recruiting
Investigative Site ES025
Alicante, 03010
- Recruiting
Investigative Site ES001
Badalona, 08916
- Recruiting
Investigative Site ES024
Badalona, 08916
- Recruiting
Investigative Site ES010
Barcelona, 08003
- Recruiting
Investigative Site ES015
Córdoba, 14004
- Recruiting
Investigative Site ES003
Granada, 18014
- Recruiting
Investigative Site ES013
Granada, 18016
- Recruiting
Investigative Site ES006
Las Palmas de Gran Canaria, 35010
- Recruiting
Investigative Site ES014
Madrid, 28034
- Recruiting
Investigative Site ES008
Madrid, 28040
- Recruiting
Investigative Site ES011
Madrid, 28041
- Recruiting
Investigative Site ES012
Madrid, 28046
- Recruiting
Investigative Site ES004
Manises, 46940
- Not yet recruiting
Investigative Site ES022
Pamplona, 31008
- Recruiting
Investigative Site ES002
Santiago de Compostela, 15706
- Not yet recruiting
Investigative Site ES021
Seville, 41013
Bulgaria13 sites, 13 recruiting
- Recruiting
Investigative Site BG008
Dupnitsa, 02600
- Recruiting
Investigative Site BG010
Lovech, 05500
- Recruiting
Investigative Site BG012
Pleven, 05800
- Recruiting
Investigative Site BG013
Plovdiv, 04002
- Not yet recruiting
Investigative Site BG015
Rousse, 07000
- Recruiting
Investigative Site BG007
Sevlievo, 05400
- Recruiting
Investigative Site BG009
Sofia, 01202
- Recruiting
Investigative Site BG002
Sofia, 01407
- Not yet recruiting
Investigative Site BG006
Sofia, 01431
- Recruiting
Investigative Site BG011
Sofia, 01431
- Recruiting
Investigative Site BG003
Sofia, 01463
- Recruiting
Investigative Site BG001
Sofia, 01510
- Not yet recruiting
Investigative Site BG014
Sofia, 01528
France13 sites, 13 recruiting
- Recruiting
Investigative Site FR014
Antony, 92160
- Recruiting
Investigative Site FR006
Bordeaux, 33000
- Recruiting
Investigative Site FR004
Brest, 29609
- Recruiting
Investigative Site FR015
Créteil, 94000
- Recruiting
Investigative Site FR009
Lyon, 69003
- Recruiting
Investigative Site FR012
Marseille, 13005
- Recruiting
Investigative Site FR011
Nantes, 44093
- Recruiting
Investigative Site FR008
Nice, 06200
- Recruiting
Investigative Site FR010
Paris, 75010
- Recruiting
Investigative Site FR005
Reims, 51100
- Recruiting
Investigative Site FR007
Rouen, 76031
- Recruiting
Investigative Site FR003
Saint-Priest-en-Jarez, 42270
- Recruiting
Investigative Site FR001
Toulouse, 31400
Italy12 sites, 12 recruiting
- Not yet recruiting
Investigative Site IT012
Bari, 70124
- Not yet recruiting
Investigative Site IT009
Brescia, 25123
- Recruiting
Investigative Site IT001
Catania, 95123
- Not yet recruiting
Investigative Site IT007
Chieti, 66013
- Not yet recruiting
Investigative Site IT014
Florence, 50125
- Not yet recruiting
Investigative Site IT010
L’Aquila, 67100
- Not yet recruiting
Investigative Site IT005
Milan, 20122
- Not yet recruiting
Investigative Site IT008
Naples, 80131
- Not yet recruiting
Investigative Site IT013
Perugia, 06129
- Recruiting
Investigative Site IT002
Rome, 00168
- Recruiting
Investigative Site IT003
Rozzano, 20089
- Recruiting
Investigative Site IT004
Torrette DI Ancona, 60020
United Kingdom11 sites, 11 recruiting
- Recruiting
Investigative Site GB003
Birmingham, B15 2GW
- Recruiting
Investigative Site GB001
Dudley, DY1 2HQ
- Recruiting
Investigative Site GB011
Ipswich, IP4 5PD
- Recruiting
Investigative Site GB013
Liverpool, L14 3LB
- Recruiting
Investigative Site GB012
London, E11 1NR
- Recruiting
Investigative Site GB014
London, SE1 9RT
- Not yet recruiting
Investigative Site GB006
Poole, BH15 2JB
- Recruiting
Investigative Site GB007
Redhill, RH1 5RH
- Recruiting
Investigative Site GB004
Salford, M6 8HD
- Recruiting
Investigative Site GR015
Whitechapel, E3 4NG
- Not yet recruiting
Investigative Site GB008
Wolverhampton, WV10 0QP
Australia9 sites, 8 recruiting
- Recruiting
Investigative Site AU001
Charleston, New South Wales, 02290
- Recruiting
Investigative Site AU008
Fremantle, 06160
- Recruiting
Investigative Site AU003
Kogarah, New South Wales, 02217
- Recruiting
Investigative Site AU005
Liverpool, New South Wales, 02170
- Recruiting
Investigative Site AU002
Melbourne, Victoria, 03002
- Completed
Investigative Site AU011
Melbourne, Victoria, 03004
- Recruiting
Investigative Site AU010
Sydney, New South Wales, 02010
- Not yet recruiting
Investigative Site AU009
Westmead, 02145
- Not yet recruiting
Investigative Site AU007
Woolloongabba, Queensland, 04102
Netherlands6 sites, 6 recruiting
- Not yet recruiting
Investigative Site NL005
Amsterdam, 1105 AZ
- Recruiting
Investigative Site NL007
Amsterdam, 1105 AZ
- Recruiting
Investigative Site NL006
Bergen op Zoom, 4624 VT
- Recruiting
Investigative Site NL003
Groningen, 9713 GZ
- Recruiting
Investigative Site NL001
Rotterdam, 3015 GD
- Not yet recruiting
Investigative Site NL004
Veldhoven, 5504 DB
Argentina5 sites, 5 recruiting
- Not yet recruiting
Investigative Site AR005
Buenos Aires, 01018
- Recruiting
Investigative Site AR002
Buenos Aires, C1060ABN
- Recruiting
Investigative Site AR004
Mar del Plata, B7600FYK
- Not yet recruiting
Investigative Site AR003
Rosario, S2000
- Not yet recruiting
Investigative Site AR001
San Miguel de Tucumán, T4000AXL
Belgium5 sites, 5 recruiting
- Recruiting
Investigative Site BE002
Brussels, 01070
- Recruiting
Investigative Site BE001
Ghent, 09000
- Recruiting
Investigative Site BE003
Liège, 04000
- Recruiting
Investigative Site BE006
Loverval, 06280
- Recruiting
Investigative Site BE005
Woluwe-Saint-Lambert, 01200
Czechia5 sites, 5 recruiting
- Recruiting
Investigative Site CZ002
Ostrava-poruba, 708 52
- Recruiting
Investigative Site CZ004
Prague, 100 00
- Recruiting
Investigative Site CZ003
Prague, 110 01
- Not yet recruiting
Investigative Site CZ001
Prague, 150 06
- Not yet recruiting
Investigative Site CZ005
Praha 13-stodulky, 158 00
South Korea5 sites, 5 recruiting
- Recruiting
Investigative Site KR006
Ansan-si, 15355
- Not yet recruiting
Investigative Site KR007
Busan, 49241
- Recruiting
Investigative Site KR003
Incheon, 21431
- Recruiting
Investigative Site KR002
Seoul, 03080
- Recruiting
Investigative Site KR001
Yangsan, 50612
Austria3 sites, 3 recruiting
- Recruiting
Investigative Site AT002
Graz, 08036
- Recruiting
Investigative Site AT004
Innsbruck, 06020
- Not yet recruiting
Investigative Site AT003
Vienna, 01130
Chile3 sites, 3 recruiting
- Recruiting
Investigative Site CL002
Santiago, 7580206
- Recruiting
Investigative Site CL003
Santiago, 8420383
- Recruiting
Investigative Site CL001
Valdivia, 5090000
Greece3 sites, 3 recruiting
- Recruiting
Investigative Site GR001
Athens, 12462
- Recruiting
Investigative Site GR002
Athens, 16121
- Recruiting
Investigative Site GR003
Thessaloniki, 56429
Hungary2 sites, 2 recruiting
- Recruiting
Investigative Site HU001
Debrecen, 04032
- Not yet recruiting
Investigative Site HU002
Szombathely
Switzerland1 site, 1 recruiting
- Recruiting
Investigative Site CH002
Zurich, 08091
About this study
Official title: A Phase 3b, Multicenter, Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Rollover study for participants from predetermined, Incyte-sponsored parent clinical trials of povorcitinib.
- Conditions
- Hidradenitis Suppurativa (HS)
- Being tested
- povorcitinib
- Keywords
- INCB054707, povorcitinib, Hidradenitis Suppurativa, Hidradenitis, HS
- Medical subject headings
- Hidradenitis Suppurativa, Hidradenitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
povorcitinibDrug
Study drug will be taken orally as defined by the protocol.
| Study group | Role | What they receive |
|---|---|---|
| povorcitinib | Experimental | Participants will receive povorcitinib treatment with the same schedule and dose options as the study in which they originally enrolled. Receives: Drug: povorcitinib |
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of participants with Treatment-Emergent Adverse Events (TEAEs)
Adverse events either reported for the first time in this Protocol or any AE ongoing and defined as treatment-emergent from the parent Protocol.
Measured: Up to approximately 3 years
Secondary outcomes (1)
Proportion of participants with a total ANdT count of 0, 1, or 2 at each visit
ANdT count is defined as the total sum of abscesses, inflammatory nodules, and draining tunnels.
Measured: Up to approximately 3 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Mar 2025
- Study start28 Feb 2025
- Primary completion28 Feb 2028 (estimated)
- Study completion28 Feb 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hidradenitis Suppurativa (HS)Studies of the same condition, open and under way.
- More trials run by Incyte CorporationThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase 3
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 600 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Incyte Corporation
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
- Investigators
- Incyte Medical Monitor, Study director, Incyte Corporation
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06855498
- Sponsor's protocol ID
- INCB054707-801
- Other IDs
- 2024-520107-12-00
- Acronym
- STOP-LTR
- Status last verified
- Oct 2026
- First submitted
- 26 Feb 2025
- Last updated
- 9 Oct 2026
- Results posted
- No
- FDA-regulated drug
- Yes
- FDA-regulated device
- No
- Individual data sharing
- Yes: Incyte shares data with qualified external researchers after a research proposal is submitted. These requests are reviewed and approved by a review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations. The trial data availability is according to the criteria and process described on https://www.incyte.com/our-company/compliance-and-transparency