Distal Radius FracturesNCT06811480
Effectiveness of Closed Kinetic Chain Exercises in Distal Radius Fracture
A study testing Conventional Physiotherapy and Closed Kinetic Chain Exercise in people with Distal Radius Fractures, run by burak menek at 1 site in Turkey (Türkiye).
Trial summary
The aim of this study is to evaluate the effectiveness of closed kinetic chain exercises during the physiotherapy and rehabilitation process following the healing of a distal radius fracture. Read more about this study
- Who is it for?
- Ages 40 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Distal Radius Fractures
- What is being tested?
- Conventional Physiotherapy and Closed Kinetic Chain Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 6 Dec 2024to 2 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Aged between 40-60 years
- Diagnosed with a distal radius fracture
- Applied to Medipol hospitals after the injury and volunteered to participate in the study
- Patients with good cooperation levels will be included in the study
Who cannot join
- Having bilateral distal radius fractures
- Having ulna styloid fractures
- Having other orthopedic, neurological, or rheumatological problems involving the ipsilateral upper extremity
- A history of surgery involving the ipsilateral upper extremity
- Associated injuries such as arterial, nerve, or tendon injuries
- Patients without adequate cooperation will be excluded from the study
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- Withdrawal Criteria:
- Missing at least one follow-up
- Development of orthopedic or systemic problems unrelated to the trauma
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effectiveness of Closed Kinetic Chain Exercises in Individuals With a Distal Radius Fracture
The aim of this study is to evaluate the effectiveness of closed kinetic chain exercises during the physiotherapy and rehabilitation process following the healing of a distal radius fracture.
A total of 40 participants aged 40-60 years who were diagnosed with distal radius fractures were randomly assigned to two groups: the conventional physiotherapy (CP) group (n=20) and the closed kinetic chain exercise (CKCE) group (n=20). Participants in the CP group underwent a 6-week standard rehabilitation program consisting of conventional physiotherapy sessions conducted 5 days a week. This program included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, Digiflex, Powerweb, and dumbbell-based strengthening exercises. In the CKCE group, the same CP program was implemented with the addition of CKCE sessions conducted five days a week for 6 weeks.
Read more
Outcome measures included joint range of motion assessed using the Goniometer Pro mobile application, functionality evaluated with the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, pain intensity measured using the Visual Analog Scale (VAS), and joint position sense assessed through the Active Repositioning Test.
CKCE may positively affect joint range of motion, arm functionality, pain, and joint position sense by improving the proprioceptive mechanism in individuals with distal radius fractures.
Read the detailed description
The aim of this study is to evaluate the effectiveness of closed kinetic chain exercises during the physiotherapy and rehabilitation process following the healing of a distal radius fracture.
Voluntary consent forms were signed by individuals willing to participate in the study, and their demographic information was recorded. A total of 40 participants were included in the study and divided into two groups:
Group 1: Conventional Physiotherapy Group (n=20) Group 2: Closed Kinetic Chain Exercise Group (n=20) Participants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. These interventions included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, and strengthening exercises using Digiflex, Powerweb, and dumbbells. The number of repetitions and sets of the exercises was adjusted based on the patients' conditions, following a progressive approach.
US was applied to the affected wrist for a total of 30 sessions, 5 days a week, once daily, for 6 minutes at an intensity of 1.5 W/cm², using an underwater application method. TENS was administered at a frequency of 100 Hertz for 20 minutes. All participants received manual stretching exercises for wrist flexion, extension, ulnar and radial deviation, supination, and pronation. These stretches were performed by a physiotherapist, with 5 repetitions in each direction, holding the end position for 20 seconds.
Participants in the second group received a treatment protocol including closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy interventions. As part of the CKCE program, the following exercises were performed with 15 repetitions each:
While the elbow was in extension and the shoulder was at 90° flexion, a ball was stabilized between the hand and the wall. The ball was rolled up and down as well as side-to-side.
While the elbow was in extension and the shoulder was at 90° abduction, a ball was stabilized between the hand and the wall. The ball was rolled up and down as well as side-to-side.
While the elbow was in extension and the shoulder was at 90° flexion, participants were asked to push against the wall by transferring body weight from the shoulder to the elbow and wrist. They held this position for 6 seconds.
Randomization:
The study included 40 participants aged between 40-60 years who were diagnosed with distal radius fractures. A computer-based randomization program was used to assign participants to groups. The randomization codes were sealed in envelopes, which were opened by the physiotherapist administering the exercises on the day of the intervention.
Outcome Measures:
Outcome measures included joint range of motion assessed using the Goniometer Pro mobile application, functionality evaluated with the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, pain intensity measured using the Visual Analog Scale (VAS), and joint position sense assessed through the Active Repositioning Test.
- Conditions
- Distal Radius Fractures
- Being tested
- Conventional Physiotherapy, Closed Kinetic Chain Exercise
- Keywords
- Closed kinetic chain exercises (CKCE), Rehabilitation, Proprioception, Distal Radius Fractures
- Medical subject headings
- Wrist Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Conventional PhysiotherapyOther
Participants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. These interventions included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, and strengthening exercises using Digiflex, Powerweb, and dumbbells. The number of repetitions and sets of the exercises was adjusted based on the patients' conditions, following a progressive approach.
US was applied to the affected wrist for a total of 30 sessions, 5 days a week, once daily, for 6 minutes at an intensity of 1.5 W/cm², using an underwater application method. TENS was administered at a frequency of 100 Hertz for 20 minutes. All participants received manual stretching exercises for wrist flexion, extension, ulnar and radial deviation, supination, and pronation. These stretches were performed by a physiotherapist, with 5 repetitions in each direction, holding the end position for 20 seconds.
Closed Kinetic Chain ExerciseOther
Participants in the second group received a treatment protocol that included closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy. CKCE exercises were performed with 15 repetitions each and involved stabilizing a ball between the hand and the wall in different arm positions, rolling it in multiple directions. Participants also performed weight-shifting exercises against a wall and on a table, holding positions for 6 seconds. Additionally, in a crawling position, they moved their unaffected arm diagonally on both a firm surface and a cushion.
| Study group | Role | What they receive |
|---|---|---|
| conventional physiotherapy (CP) group | Active comparator | Participants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. Receives: Other: Conventional Physiotherapy |
| closed kinetic chain exercises (CKCE) group | Experimental | Participants in the second group received a treatment protocol including closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy interventions. Receives: Other: Conventional Physiotherapy; Other: Closed Kinetic Chain Exercise |
What is being measured
The primary outcome is the main question the study is designed to answer.
JPS testing
Joint position sense (JPS) testing was conducted using a standardized protocol with a goniometer for active wrist position measurement. Participants, seated with their elbow flexed on a table, had their wrist passively moved to 30º extension to memorize the position. With vision occluded, they moved their wrist to full flexion and attempted to reproduce the 30º extension. The reproduced wrist position was recorded, and the difference from the reference angle determined the JPS deficit. A zero value indicated perfect reproduction, while absolute differences reflected the deficit's magnitude. Two trials' mean values were used for analysis.
Measured: From enrollment to the end of treatment at 8 weeks
Goniometric Measurement
In this study, the affected shoulder's flexion, extension, abduction, internal rotation, and external rotation angles will be measured using a goniometer-pro application. Reference values will include 0-180 degrees for flexion and abduction, 45 degrees for extension, and 0-90 degrees for internal and external rotation
Measured: From enrollment to the end of treatment at 8 weeks
Secondary outcomes (2)
Visual Analog Scale (VAS)
The Visual Analog Scale (VAS) is a commonly used tool in clinical settings for assessing pain intensity. Participants rate their pain on a scale from 0 to 10, where 0 indicates no pain, and 10 represents unbearable pain. Pain intensity at rest and during activity will be evaluated using the VAS for participants before and after the treatment
Measured: From enrollment to the end of treatment at 8 weeks
Disabilities of the Arm, Shoulder, and Hand (DASH)
The DASH questionnaire, introduced in collaboration with the American Academy of Orthopedic Surgeons and other organizations, evaluates physical limitations and functionality in upper extremity problems (10). The DASH consists of three subsections. The first section includes 30 questions: 21 assess difficulties in daily living activities, 5 evaluate symptoms, and 4 measure social function, work, sleep, and self-confidence. An optional module (Work Module (DASH-W)) with 4 additional questions assesses the impact on work life
Measured: From enrollment to the end of treatment at 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Feb 2025
- Study start6 Dec 2024
- Primary completion9 Mar 2025
- Study completion2 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Distal Radius FracturesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- burak menek
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, burak menek, Istanbul Medipol University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06811480
- Sponsor's protocol ID
- E-10840098-202.3.02-7483
- Status last verified
- Apr 2025
- First submitted
- 31 Jan 2025
- Last updated
- 4 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Menek B, Dansuk E. Investigating the effects of closed kinetic chain exercises on joint position sense, functionality, range of motion, and pain in individuals with distal radius fracture: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 May 31;17(1):137. doi: 10.1186/s13102-025-01195-2.
PubMed 40450369
Study at a glance
From the registry record, last updated by the sponsor on 4 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Closed Kinetic Chain Exercises in Individuals With a Distal Radius Fracture
- ClinicalTrials.gov ID
- NCT06811480
- Acronym / sponsor ID
- E-10840098-202.3.02-7483
- Conditions
- Distal Radius Fractures
- Keywords
- Closed kinetic chain exercises (CKCE), Rehabilitation, Proprioception, Distal Radius Fractures
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- burak menekUniversity, hospital or other
- Study start
- 6 Dec 2024 (actual)
- Primary completion
- 9 Mar 2025 (actual)
- Study completion
- 2 Apr 2025 (actual)
- First posted
- 6 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this study is to evaluate the effectiveness of closed kinetic chain exercises during the physiotherapy and rehabilitation process following the healing of a distal radius fracture.
A total of 40 participants aged 40-60 years who were diagnosed with distal radius fractures were randomly assigned to two groups: the conventional physiotherapy (CP) group (n=20) and the closed kinetic chain exercise (CKCE) group (n=20). Participants in the CP group underwent a 6-week standard rehabilitation program consisting of conventional physiotherapy sessions conducted 5 days a week. This program included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, Digiflex, Powerweb, and dumbbell-based strengthening exercises. In the CKCE group, the same CP program was implemented with the addition of CKCE sessions conducted five days a week for 6 weeks.
Outcome measures included joint range of motion assessed using the Goniometer Pro mobile application, functionality evaluated with the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, pain intensity measured using the Visual Analog Scale (VAS), and joint position sense assessed through the Active Repositioning Test.
CKCE may positively affect joint range of motion, arm functionality, pain, and joint position sense by improving the proprioceptive mechanism in individuals with distal radius fractures.
Detailed description
The aim of this study is to evaluate the effectiveness of closed kinetic chain exercises during the physiotherapy and rehabilitation process following the healing of a distal radius fracture.
Voluntary consent forms were signed by individuals willing to participate in the study, and their demographic information was recorded. A total of 40 participants were included in the study and divided into two groups:
Group 1: Conventional Physiotherapy Group (n=20) Group 2: Closed Kinetic Chain Exercise Group (n=20) Participants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. These interventions included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, and strengthening exercises using Digiflex, Powerweb, and dumbbells. The number of repetitions and sets of the exercises was adjusted based on the patients' conditions, following a progressive approach.
US was applied to the affected wrist for a total of 30 sessions, 5 days a week, once daily, for 6 minutes at an intensity of 1.5 W/cm², using an underwater application method. TENS was administered at a frequency of 100 Hertz for 20 minutes. All participants received manual stretching exercises for wrist flexion, extension, ulnar and radial deviation, supination, and pronation. These stretches were performed by a physiotherapist, with 5 repetitions in each direction, holding the end position for 20 seconds.
Participants in the second group received a treatment protocol including closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy interventions. As part of the CKCE program, the following exercises were performed with 15 repetitions each:
While the elbow was in extension and the shoulder was at 90° flexion, a ball was stabilized between the hand and the wall. The ball was rolled up and down as well as side-to-side.
While the elbow was in extension and the shoulder was at 90° abduction, a ball was stabilized between the hand and the wall. The ball was rolled up and down as well as side-to-side.
While the elbow was in extension and the shoulder was at 90° flexion, participants were asked to push against the wall by transferring body weight from the shoulder to the elbow and wrist. They held this position for 6 seconds.
Randomization:
The study included 40 participants aged between 40-60 years who were diagnosed with distal radius fractures. A computer-based randomization program was used to assign participants to groups. The randomization codes were sealed in envelopes, which were opened by the physiotherapist administering the exercises on the day of the intervention.
Outcome Measures:
Outcome measures included joint range of motion assessed using the Goniometer Pro mobile application, functionality evaluated with the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, pain intensity measured using the Visual Analog Scale (VAS), and joint position sense assessed through the Active Repositioning Test.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| conventional physiotherapy (CP) group | Active comparator | Other: Conventional PhysiotherapyParticipants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. |
| closed kinetic chain exercises (CKCE) group | Experimental | Other: Conventional Physiotherapy, Other: Closed Kinetic Chain ExerciseParticipants in the second group received a treatment protocol including closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy interventions. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Aged between 40-60 years
- Diagnosed with a distal radius fracture
- Applied to Medipol hospitals after the injury and volunteered to participate in the study
- Patients with good cooperation levels will be included in the study
Key exclusion criteria (9 listed)
- Having bilateral distal radius fractures
- Having ulna styloid fractures
- Having other orthopedic, neurological, or rheumatological problems involving the ipsilateral upper extremity
- A history of surgery involving the ipsilateral upper extremity
- Associated injuries such as arterial, nerve, or tendon injuries
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Conventional PhysiotherapyParticipants in the first group underwent conventional physiotherapy interventions for 6 weeks, 5 days per week. These interventions included Ultrasound (US), Transcutaneous Electrical Nerve Stimulation (TENS), wrist joint range of motion exercises, stretching exercises, and strengthening exercises using Digiflex, Powerweb, and dumbbells. The number of repetitions and sets of the exercises was adjusted based on the patients' conditions, following a progressive approach. US was applied to the affected wrist for a total of 30 sessions, 5 days a week, once daily, for 6 minutes at an intensity of 1.5 W/cm², using an underwater application method. TENS was administered at a frequency of 100 Hertz for 20 minutes. All participants received manual stretching exercises for wrist flexion, extension, ulnar and radial deviation, supination, and pronation. These stretches were performed by a physiotherapist, with 5 repetitions in each direction, holding the end position for 20 seconds. | Other | closed kinetic chain exercises (CKCE) group, conventional physiotherapy (CP) group |
| Closed Kinetic Chain ExerciseParticipants in the second group received a treatment protocol that included closed kinetic chain exercises (CKCE) in addition to conventional physiotherapy. CKCE exercises were performed with 15 repetitions each and involved stabilizing a ball between the hand and the wall in different arm positions, rolling it in multiple directions. Participants also performed weight-shifting exercises against a wall and on a table, holding positions for 6 seconds. Additionally, in a crawling position, they moved their unaffected arm diagonally on both a firm surface and a cushion. | Other | closed kinetic chain exercises (CKCE) group |
Primary outcome
JPS testing
Time frame: From enrollment to the end of treatment at 8 weeks
Joint position sense (JPS) testing was conducted using a standardized protocol with a goniometer for active wrist position measurement. Participants, seated with their elbow flexed on a table, had their wrist passively moved to 30º extension to memorize the position. With vision occluded, they moved their wrist to full flexion and attempted to reproduce the 30º extension. The reproduced wrist position was recorded, and the difference from the reference angle determined the JPS deficit. A zero value indicated perfect reproduction, while absolute differences reflected the deficit's magnitude. Two trials' mean values were used for analysis.
Goniometric Measurement
Time frame: From enrollment to the end of treatment at 8 weeks
In this study, the affected shoulder's flexion, extension, abduction, internal rotation, and external rotation angles will be measured using a goniometer-pro application. Reference values will include 0-180 degrees for flexion and abduction, 45 degrees for extension, and 0-90 degrees for internal and external rotation
2 secondary outcomes
Visual Analog Scale (VAS)
Time frame: From enrollment to the end of treatment at 8 weeks
Disabilities of the Arm, Shoulder, and Hand (DASH)
Time frame: From enrollment to the end of treatment at 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Apr 2025.
- Derived from this study: PubMed 40450369Menek B, Dansuk E. Investigating the effects of closed kinetic chain exercises on joint position sense, functionality, range of motion, and pain in individuals with distal radius fracture: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2025 May 31;17(1):137. doi: 10.1186/s13102-025-01195-2.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Conventional Physiotherapy and Closed Kinetic Chain Exercise in people with Distal Radius Fractures, run by burak menek at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
JPS testing (time frame: From enrollment to the end of treatment at 8 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06811480, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Apr 2025.