Meralgia ParestheticaNCT06751147
Effects of Lateral Femoral Cutaneous Nerve Mobilization With and Without Muscle Energy Techniques in Pregnant Females
A study testing Group A and Experimental Group B in people with Meralgia Paresthetica, run by Riphah International University at 2 sites in Pakistan.
Trial summary
The rationale of this study is to provide empirical evidence regarding the efficacy and safety of neural mobilization in pregnant women with meralgia paresthetica. By investigating the potential benefits of this intervention, healthcare professionals can make informed decisions about incorporating neural mobilization… Read more about this study
- Who is it for?
- Ages 18 to 40 years, women only
- Conditions the study is for
- Meralgia Paresthetica
- What is being tested?
- Group A and Experimental Group B
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 48 participants
- Where
- 2 sitesPakistan
- Study dates
- 23 Dec 2024to 15 May 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Age ranges from 18 to 40 years
- Body mass index ≥25kg/m2.
- Pregnant females in third trimester diagnosed with myalgia paraesthetica.
- Multigravida pregnant females
- Patients will be screened through Prone Knee Bend (PKB) test for femoral nerve compression.
- Positive pelvic compression test(1)
Who cannot join
- Those having other entrapment syndromes or radicular symptoms
- Motor weakness
- Having a history or ongoing cancerous proliferation
- Active infection
Trial locations and contacts
2 sites in 1 country.
Pakistan2 sites
Ghurkhi Hospital
Lahore, Punjab Province
Ghurki Hospital
Lahore, Punjab Province
About this study
Official title: Effects of Lateral Femoral Cutaneous Nerve Mobilization With and Without Muscle Energy Techniques on Neuropathic Pain, Knee Range of Motion and Quality of Life in Pregnant Females
The rationale of this study is to provide empirical evidence regarding the efficacy and safety of neural mobilization in pregnant women with meralgia paresthetica. By investigating the potential benefits of this intervention, healthcare professionals can make informed decisions about incorporating neural mobilization into the management of this condition during pregnancy. Focusing on the impact of neural mobilization and muscle energy techniques on both neuropathic pain and quality of life aligns with a patient-centered approach to care. The goal is not only to reduce symptoms but also to enhance overall well-being and functional capacity
Read the detailed description
The literature gap of the study is that upto our knowledge, there is little or no evidence found in previous researches on the combined effects of lateral femoral cutaneous nerve mobilization in combination with MET in pregnant females. Secondly no quantitative measurement as range of motion with goniometer has been yet studied
- Conditions
- Meralgia Paresthetica
- Being tested
- Group A, Experimental Group B
- Keywords
- femoral neuropathy
- Medical subject headings
- Femoral Neuropathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group AOther
It consists of 24 patients who were assessed by prone knee bend (PKB) test and knee range of motion was measured by goniometer. In addition to traditional physical therapy and muscle energy procedures, patients in this group received neural mobilization. The patient laid on their side with their knee bent to a 90-degree angle and the affected side looking up while neural mobilization was carried out. The therapist then performed the technique by abducting and extending the patient's hip. Five repetitions of the nerve stretch were performed, each with a 10-second hold and a 5-second rest in between.
METs were implemented in two positions using post-isometric relaxation (PIR): In this initial posture, the patient laid on their back with the affected leg just over the bed's edge. With one hand, the physiotherapist stood facing the affected side and pressed the contralateral ASIS to keep the patient from rolling off the bed. The therapist, however, simultaneously grabbed the femur dist
Experimental Group BOther
It involves 24 patients who had received the neural mobilization described above along with traditional physical therapy that does not involve muscular energy techniques. The treatment took place in the outpatient physical therapy department and lasted around thirty minutes in total
| Study group | Role | What they receive |
|---|---|---|
| group A | Experimental | Lateral Femoral cutaneous nerve mobilization with muscle energy techniques Receives: Other: Group A |
| GROUP B | Experimental | Not described Receives: Other: Experimental Group B |
What is being measured
The primary outcome is the main question the study is designed to answer.
quality of life is assessed by QOL questioner
EQ-5D is used to measure quality of life
Measured: at base line pre intervention, at the end of 4th week post intervention
Knee range of motion is used to measure ROM
measured by goniometer
Measured: at base line pre intervention, at the end of 4th week post intervention
neuropathic pain
The Neuropathic Pain Scale (NPS) is a tool used to assess the specific qualities of pain associated with neuropathic pain. It helps differentiate neuropathic pain from other types of pain by evaluating different pain sensations and their intensity. The NPS consists of 10 items, each rated on a scale of 0 to 10, where 0 is "no pain" and 10 is the "worst imaginable pain".
Measured: at base line pre intervention, at the end of 4th week post intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Dec 2024
- Study start23 Dec 2024
- Primary completion15 May 2025
- Study completion15 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Meralgia ParestheticaStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 48 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Iqra abdul ghafoor, PPDPT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06751147
- Sponsor's protocol ID
- REC/00234 Mehwish
- Status last verified
- Jul 2025
- First submitted
- 20 Dec 2024
- Last updated
- 25 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Lateral Femoral Cutaneous Nerve Mobilization With and Without Muscle Energy Techniques on Neuropathic Pain, Knee Range of Motion and Quality of Life in Pregnant Females
- ClinicalTrials.gov ID
- NCT06751147
- Acronym / sponsor ID
- REC/00234 Mehwish
- Conditions
- Meralgia Paresthetica
- Keywords
- femoral neuropathy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 48 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 23 Dec 2024 (actual)
- Primary completion
- 15 May 2025 (actual)
- Study completion
- 15 May 2025 (actual)
- First posted
- 27 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The rationale of this study is to provide empirical evidence regarding the efficacy and safety of neural mobilization in pregnant women with meralgia paresthetica. By investigating the potential benefits of this intervention, healthcare professionals can make informed decisions about incorporating neural mobilization into the management of this condition during pregnancy. Focusing on the impact of neural mobilization and muscle energy techniques on both neuropathic pain and quality of life aligns with a patient-centered approach to care. The goal is not only to reduce symptoms but also to enhance overall well-being and functional capacity
Detailed description
The literature gap of the study is that upto our knowledge, there is little or no evidence found in previous researches on the combined effects of lateral femoral cutaneous nerve mobilization in combination with MET in pregnant females. Secondly no quantitative measurement as range of motion with goniometer has been yet studied
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| group A | Experimental | Other: Group ALateral Femoral cutaneous nerve mobilization with muscle energy techniques |
| GROUP B | Experimental | Other: Experimental Group B |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Age ranges from 18 to 40 years
- Body mass index ≥25kg/m2.
- Pregnant females in third trimester diagnosed with myalgia paraesthetica.
- Multigravida pregnant females
- Patients will be screened through Prone Knee Bend (PKB) test for femoral nerve compression.
Key exclusion criteria (4 listed)
- Those having other entrapment syndromes or radicular symptoms
- Motor weakness
- Having a history or ongoing cancerous proliferation
- Active infection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group AIt consists of 24 patients who were assessed by prone knee bend (PKB) test and knee range of motion was measured by goniometer. In addition to traditional physical therapy and muscle energy procedures, patients in this group received neural mobilization. The patient laid on their side with their knee bent to a 90-degree angle and the affected side looking up while neural mobilization was carried out. The therapist then performed the technique by abducting and extending the patient's hip. Five repetitions of the nerve stretch were performed, each with a 10-second hold and a 5-second rest in between. METs were implemented in two positions using post-isometric relaxation (PIR): In this initial posture, the patient laid on their back with the affected leg just over the bed's edge. With one hand, the physiotherapist stood facing the affected side and pressed the contralateral ASIS to keep the patient from rolling off the bed. The therapist, however, simultaneously grabbed the femur dist | Other | group A |
| Experimental Group BIt involves 24 patients who had received the neural mobilization described above along with traditional physical therapy that does not involve muscular energy techniques. The treatment took place in the outpatient physical therapy department and lasted around thirty minutes in total | Other | GROUP B |
Primary outcome
quality of life is assessed by QOL questioner
Time frame: at base line pre intervention, at the end of 4th week post intervention
EQ-5D is used to measure quality of life
Knee range of motion is used to measure ROM
Time frame: at base line pre intervention, at the end of 4th week post intervention
measured by goniometer
neuropathic pain
Time frame: at base line pre intervention, at the end of 4th week post intervention
The Neuropathic Pain Scale (NPS) is a tool used to assess the specific qualities of pain associated with neuropathic pain. It helps differentiate neuropathic pain from other types of pain by evaluating different pain sensations and their intensity. The NPS consists of 10 items, each rated on a scale of 0 to 10, where 0 is "no pain" and 10 is the "worst imaginable pain".
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Jul 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Iqra abdul ghafoor, PPDPT principal investigator
Riphah International University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group A and Experimental Group B in people with Meralgia Paresthetica, run by Riphah International University at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
quality of life is assessed by QOL questioner (time frame: at base line pre intervention, at the end of 4th week post intervention). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Jul 2025.