Streptobacillus Moniliformis InfectionsStreptobacilNCT06711861
Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France
An observational study of Streptobacillus Moniliformis Infections, run by University Hospital, Strasbourg, France at 1 site in France.
Trial summary
French data on Streptobacillus moniliformis infections (zoonosis transmitted by rat bites) are rare and there are no case series in the literature to date. This is a pathology presenting atypical clinical manifestations for a bacterial infection and which therefore remains underdiagnosed. Read more about this study
- Who is it for?
- Ages 1 year and older
- Conditions the study is for
- Streptobacillus Moniliformis Infections
- How many people
- 20 participants
- Where
- 1 siteFrance
- Study dates
- 16 Feb 2024to 16 Feb 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 1 year and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Patient having Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023
Who may be able to join
- Minor patient aged 1 to 17 years
- Adult patient ≥18 years
- Proven Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023
- Subject not objecting, after being informed, to the reuse of their data for the purposes of this research
- Holders of parental authority not objecting, after being informed, to the reuse of their data for the purposes of this research their child for the purposes of this research
Who cannot join
- Subject and/or holder of parental authority having expressed opposition to participating in the study
Trial locations and contacts
1 site in 1 country.
France1 site, 1 recruiting
- Recruiting
Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France
Strasbourg, 67091
François DANION, MD, 33 3 69 55 15 88, francois.danion@chru-strasbourg.fr
François DANION, MD
About this study
French data on Streptobacillus moniliformis infections (zoonosis transmitted by rat bites) are rare and there are no case series in the literature to date. This is a pathology presenting atypical clinical manifestations for a bacterial infection and which therefore remains underdiagnosed. Streptobacillus moniliformis infections can be fatal without appropriate antibiotic treatment. This study could improve diagnosis, develop early treatment strategies and contribute to the overall understanding of zoonotic diseases
- Conditions
- Streptobacillus Moniliformis Infections
- Keywords
- Streptobacillus moniliformis, Zoonosis, Rat bites, Zoonotic diseases
- Medical subject headings
- Rat-Bite Fever, Zoonoses
What is being measured
The primary outcome is the main question the study is designed to answer.
Retrospective study of the effectiveness of antibiotic therapy initiated for the treatment of Streptobacillus moniliformis infection.
Clinical cure 15 days after the start of antibiotic therapy. This cure is based on a negative blood culture (absence of germs) performed 15 days after the start of treatment.
Measured: Negative blood culture 15 days after the start of antibiotic therapy.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Dec 2024
- Study start16 Feb 2024
- Primary completion16 Feb 2025 (estimated)
- Study completion16 Feb 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Streptobacillus Moniliformis InfectionsStudies of the same condition, open and under way.
- More trials run by University Hospital, Strasbourg, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Strasbourg, France
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06711861
- Sponsor's protocol ID
- 9237
- Acronym
- Streptobacil
- Status last verified
- Aug 2024
- First submitted
- 21 Aug 2024
- Last updated
- 2 Dec 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Dec 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Multicenter Retrospective Study on Streptobacillus Moniliformis Infections in France
- ClinicalTrials.gov ID
- NCT06711861
- Acronym / sponsor ID
- Streptobacil / 9237
- Conditions
- Streptobacillus Moniliformis Infections
- Keywords
- Streptobacillus moniliformis, Zoonosis, Rat bites, Zoonotic diseases
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- University Hospital, Strasbourg, FranceUniversity, hospital or other
- Study start
- 16 Feb 2024 (actual)
- Primary completion
- 16 Feb 2025 (estimated)
- Study completion
- 16 Feb 2025 (estimated)
- First posted
- 2 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
French data on Streptobacillus moniliformis infections (zoonosis transmitted by rat bites) are rare and there are no case series in the literature to date. This is a pathology presenting atypical clinical manifestations for a bacterial infection and which therefore remains underdiagnosed. Streptobacillus moniliformis infections can be fatal without appropriate antibiotic treatment. This study could improve diagnosis, develop early treatment strategies and contribute to the overall understanding of zoonotic diseases
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
Who may qualify
- Ages
- 1 year and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patient having Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023
Key inclusion criteria (5 listed)
- Minor patient aged 1 to 17 years
- Adult patient ≥18 years
- Proven Streptobacillus moniliformis infection between 01/01/2007 and 31/12/2023
- Subject not objecting, after being informed, to the reuse of their data for the purposes of this research
- Holders of parental authority not objecting, after being informed, to the reuse of their data for the purposes of this research their child for the purposes of this research
Key exclusion criteria (1 listed)
- Subject and/or holder of parental authority having expressed opposition to participating in the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Retrospective study of the effectiveness of antibiotic therapy initiated for the treatment of Streptobacillus moniliformis infection.
Time frame: Negative blood culture 15 days after the start of antibiotic therapy.
Clinical cure 15 days after the start of antibiotic therapy. This cure is based on a negative blood culture (absence of germs) performed 15 days after the start of treatment.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Dec 2024.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Streptobacillus Moniliformis Infections, run by University Hospital, Strasbourg, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 2 Dec 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact François DANION, MD (33 3 69 55 15 88, francois.danion@chru-strasbourg.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Retrospective study of the effectiveness of antibiotic therapy initiated for the treatment of Streptobacillus moniliformis infection. (time frame: Negative blood culture 15 days after the start of antibiotic therapy.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Dec 2024.