Adolescent Idiopathic Scoliosis (AIS)NCT06682702
Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises With Schroth in Adolescent Idiopathic Scoliosis
A study testing DNS Group and Schroth Group in people with Adolescent Idiopathic Scoliosis (AIS), run by Uskudar University at 1 site in Turkey (Türkiye).
Trial summary
In our study, the degree of scoliosis curvature in volunteers will be determined using full-body standing X-rays. Additionally, the rotation degree of the spinal curvature in volunteers will be assessed with a scoliosis meter (a type of ruler) through the forward bending test while standing. Read more about this study
- Who is it for?
- Ages 10 to 18 yearsHealthy volunteers can take part
- Conditions the study is for
- Adolescent Idiopathic Scoliosis (AIS)
- What is being tested?
- DNS Group and Schroth Group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 26 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Nov 2024to 7 Mar 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 10 to 18 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Radiologically measured Cobb angle value between 10 degrees and 50 degrees
- Age between 10 and 18
- Being diagnosed with Adolescent Idiopathic Scoliosis by a physician
- Being between 0 and 5 in the radiologically determined Risser sign
- Being between 12-25 kg/m2 according to body mass index measurement
Who cannot join
- Having had any surgery related to scoliosis
- Having been diagnosed with any psychiatric disease
- Having been diagnosed with an oncological disease
- Having a neurological disease, vestibular or visual problem
- Having any pathology that will affect motor performance
- Using medication that affects the central nervous system
- Having been diagnosed with a rheumatological disease
- Having been diagnosed with any cardiovascular disease
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Uskudar University Physiotherapy and Rehabilitation Application and Research Center
Istanbul
About this study
Official title: The Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises in Addition to Schroth Exercises in Individuals With Adolescent Idiopathic Scoliosis
In our study, the degree of scoliosis curvature in volunteers will be determined using full-body standing X-rays. Additionally, the rotation degree of the spinal curvature in volunteers will be assessed with a scoliosis meter (a type of ruler) through the forward bending test while standing. To measure the impact of scoliosis on the quality of life, the SRS-22 questionnaire, consisting of 22 questions, will be used. The level of pain experienced by volunteers as a result of scoliosis will be evaluated using the visual analog scale (VAS), where pain intensity is marked on a 10 centimeter line. Lastly, the volunteers; breathing patterns will be assessed by measuring chest circumference with a tape measure.
Read the detailed description
In this randomized controlled trial, we aim to assess various physical and quality of life parameters in volunteers with scoliosis. The degree of spinal curvature will be measured using full body standing X-rays, providing a detailed assessment of the scoliosis angle. Additionally, the rotation degree of the spinal curvature will be evaluated with a scoliosis meter during the forward bending test, which is commonly used to gauge the rotational component of scoliosis.
Quality of life will be assessed using the Scoliosis Research Society-22 (SRS-22) questionnaire, a validated tool consisting of 22 questions designed to evaluate function, pain, self image, mental health, and satisfaction in individuals with scoliosis. To quantify pain levels experienced due to scoliosis, the Visual Analog Scale (VAS) will be used, in which participants mark their pain intensity on a 10 centimeter line, ranging from "no pain" to "worst pain imaginable." This provides an accurate, subjective measure of pain severity.
Breathing patterns will also be evaluated by measuring the volunteers' chest circumference at full inspiration and expiration using a standard tape measure, allowing us to assess any potential restrictions in lung expansion related to the spinal curvature. Through this comprehensive evaluation, we hope to gain a clearer understanding of how scoliosis affects both the physical and psychological well being of individuals and identify potential areas for therapeutic intervention.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS)
- Being tested
- DNS Group, Schroth Group
- Keywords
- rehabilitation, surgery, therapy, Rehabilitation Exercise, Exercise Therapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
DNS GroupOther
Also called Schroth Exercise, Dynamic Neuromuscular Stabilization
ISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions. Dynamic neuromuscular stabilization exercises, on the other hand, are designed to achieve sagittal stabilization by utilizing the stabilizing function of the thoracic diaphragm muscle.
Schroth GroupOther
Also called Schroth Exercise
ISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions.
| Study group | Role | What they receive |
|---|---|---|
| DNS Group | Experimental | Patients diagnosed with adolescent idiopathic scoliosis participated in sessions twice a week for 8 weeks, with each session lasting 45 minutes. During the sessions, ISST Schroth exercises were combined with dynamic neuromuscular stabilization exercises. Receives: Other: DNS Group |
| Schroth Group | Experimental | Patients diagnosed with adolescent idiopathic scoliosis participated in sessions twice a week for 8 weeks, with each session lasting 45 minutes. During the sessions, ISST Schroth exercises were performed. Receives: Other: Schroth Group |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cobb Angel
The Cobb angle will be measured using standing full-spine X-rays to quantify the degree of spinal curvature in patients with scoliosis.
Measured: 8 weeks
Respiratory Muscle Strength
Respiratory muscle strength was measured using an electronic mouth pressure measuring device (Cosmed Ponyy Fx, Rome, Italy). Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were measured.
Measured: 8 weeks
Angle Trunk Rotation
The Adams forward bending test, commonly used in scoliosis screening, involves positioning the patient with arms extended forward to assess for asymmetric protrusions and coronal imbalance in the back, while a scoliometer is utilized to measure the degree of spinal rotation and track progression of trunk asymmetry and deformity.
Measured: 8 weeks
Secondary outcomes (2)
Visual Analog Scale
The Visual Analog Scale (VAS) will be used to measure pain intensity by having participants mark their perceived level of pain on a 10-centimeter line ranging from 'no pain' to 'worst pain imaginable.
Measured: 8 weeks
Scoliosis Research Society-22 (SRS-22) Quality of Life Questionnaire
The Scoliosis Research Society-22 (SRS-22) Quality of Life Questionnaire measures the impact of scoliosis on patients' quality of life across five domains: function, pain, self-image, mental health, and satisfaction, using a total of 22 questions.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Nov 2024
- Study start15 Nov 2024
- Primary completion7 Jan 2025
- Study completion7 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Adolescent Idiopathic Scoliosis (AIS)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Model description training and control group
- Masking
- None (open label)
- Enrolment
- 26 participants (actual)
Sponsor and investigators
- Lead sponsor
- Uskudar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, MERVE BAŞARDI, Uskudar University
- Investigators
- Filiz Eyuboglu, PhD., Study director, Uskudar UniversityMert Ilhan, MSc., Principal investigator, Uskudar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06682702
- Sponsor's protocol ID
- 2024-PT-MRVB-RCT
- Status last verified
- Mar 2026
- First submitted
- 22 Oct 2024
- Last updated
- 27 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Eyuboglu F, Ilhan M, Basardi M, Kolayli Cerezci T. Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises Combined With Schroth Exercises in the Treatment of Moderate Idiopathic Scoliosis. Biol Res Nurs. 2026 Oct 27:10998004261496448. doi: 10.1177/10998004261496448. Online ahead of print.
PubMed 42947470
Study at a glance
From the registry record, last updated by the sponsor on 27 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises in Addition to Schroth Exercises in Individuals With Adolescent Idiopathic Scoliosis
- ClinicalTrials.gov ID
- NCT06682702
- Acronym / sponsor ID
- 2024-PT-MRVB-RCT
- Conditions
- Adolescent Idiopathic Scoliosis (AIS)
- Keywords
- rehabilitation, surgery, therapy, Rehabilitation Exercise, Exercise Therapy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 26 participants (actual)
- Lead sponsor
- Uskudar UniversityUniversity, hospital or other
- Study start
- 15 Nov 2024 (actual)
- Primary completion
- 7 Jan 2025 (actual)
- Study completion
- 7 Mar 2025 (actual)
- First posted
- 12 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In our study, the degree of scoliosis curvature in volunteers will be determined using full-body standing X-rays. Additionally, the rotation degree of the spinal curvature in volunteers will be assessed with a scoliosis meter (a type of ruler) through the forward bending test while standing. To measure the impact of scoliosis on the quality of life, the SRS-22 questionnaire, consisting of 22 questions, will be used. The level of pain experienced by volunteers as a result of scoliosis will be evaluated using the visual analog scale (VAS), where pain intensity is marked on a 10 centimeter line. Lastly, the volunteers; breathing patterns will be assessed by measuring chest circumference with a tape measure.
Detailed description
In this randomized controlled trial, we aim to assess various physical and quality of life parameters in volunteers with scoliosis. The degree of spinal curvature will be measured using full body standing X-rays, providing a detailed assessment of the scoliosis angle. Additionally, the rotation degree of the spinal curvature will be evaluated with a scoliosis meter during the forward bending test, which is commonly used to gauge the rotational component of scoliosis.
Quality of life will be assessed using the Scoliosis Research Society-22 (SRS-22) questionnaire, a validated tool consisting of 22 questions designed to evaluate function, pain, self image, mental health, and satisfaction in individuals with scoliosis. To quantify pain levels experienced due to scoliosis, the Visual Analog Scale (VAS) will be used, in which participants mark their pain intensity on a 10 centimeter line, ranging from "no pain" to "worst pain imaginable." This provides an accurate, subjective measure of pain severity.
Breathing patterns will also be evaluated by measuring the volunteers' chest circumference at full inspiration and expiration using a standard tape measure, allowing us to assess any potential restrictions in lung expansion related to the spinal curvature. Through this comprehensive evaluation, we hope to gain a clearer understanding of how scoliosis affects both the physical and psychological well being of individuals and identify potential areas for therapeutic intervention.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Model description training and control group
| Arm | Type | Receives |
|---|---|---|
| DNS Group | Experimental | Other: DNS GroupPatients diagnosed with adolescent idiopathic scoliosis participated in sessions twice a week for 8 weeks, with each session lasting 45 minutes. During the sessions, ISST Schroth exercises were combined with dynamic neuromuscular stabilization exercises. |
| Schroth Group | Experimental | Other: Schroth GroupPatients diagnosed with adolescent idiopathic scoliosis participated in sessions twice a week for 8 weeks, with each session lasting 45 minutes. During the sessions, ISST Schroth exercises were performed. |
Who may qualify
- Ages
- 10 to 18 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Radiologically measured Cobb angle value between 10 degrees and 50 degrees
- Age between 10 and 18
- Being diagnosed with Adolescent Idiopathic Scoliosis by a physician
- Being between 0 and 5 in the radiologically determined Risser sign
- Being between 12-25 kg/m2 according to body mass index measurement
Key exclusion criteria (8 listed)
- Having had any surgery related to scoliosis
- Having been diagnosed with any psychiatric disease
- Having been diagnosed with an oncological disease
- Having a neurological disease, vestibular or visual problem
- Having any pathology that will affect motor performance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| DNS GroupAlso: Schroth Exercise, Dynamic Neuromuscular StabilizationISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions. Dynamic neuromuscular stabilization exercises, on the other hand, are designed to achieve sagittal stabilization by utilizing the stabilizing function of the thoracic diaphragm muscle. | Other | DNS Group |
| Schroth GroupAlso: Schroth ExerciseISST Schroth exercises are a model of exercise aimed at correcting scoliosis in three dimensions. | Other | Schroth Group |
Primary outcome
Cobb Angel
Time frame: 8 weeks
The Cobb angle will be measured using standing full-spine X-rays to quantify the degree of spinal curvature in patients with scoliosis.
Respiratory Muscle Strength
Time frame: 8 weeks
Respiratory muscle strength was measured using an electronic mouth pressure measuring device (Cosmed Ponyy Fx, Rome, Italy). Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were measured.
Angle Trunk Rotation
Time frame: 8 weeks
The Adams forward bending test, commonly used in scoliosis screening, involves positioning the patient with arms extended forward to assess for asymmetric protrusions and coronal imbalance in the back, while a scoliometer is utilized to measure the degree of spinal rotation and track progression of trunk asymmetry and deformity.
2 secondary outcomes
Visual Analog Scale
Time frame: 8 weeks
Scoliosis Research Society-22 (SRS-22) Quality of Life Questionnaire
Time frame: 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Mar 2026.
- Derived from this study: PubMed 42947470Eyuboglu F, Ilhan M, Basardi M, Kolayli Cerezci T. Effectiveness of Dynamic Neuromuscular Stabilization Breathing Exercises Combined With Schroth Exercises in the Treatment of Moderate Idiopathic Scoliosis. Biol Res Nurs. 2026 Oct 27:10998004261496448. doi: 10.1177/10998004261496448. Online ahead of print.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Filiz Eyuboglu, PhD. study director
Uskudar University
Mert Ilhan, MSc. principal investigator
Uskudar University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing DNS Group and Schroth Group in people with Adolescent Idiopathic Scoliosis (AIS), run by Uskudar University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 27 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cobb Angel (time frame: 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06682702, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Mar 2026.