Behavior Change InterventionsNCT06679647
Acceptability, Usability and Preliminary Effectiveness of ChatGPT in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults in Hong Kong
A study testing Access to a trained ChatGPT in people with Behavior Change Interventions, run by Chinese University of Hong Kong.
Trial summary
In this project, we will train a ChatGPT to provide real-time answers to questions related to the SIV for older adults in Hong Kong. This study aims to evaluate the usability, acceptability, and preliminary effectiveness of the ChatGPT among 50 community-living people aged 65 years and above in Hong Kong. Read more about this study
- Who is it for?
- Ages 65 years and olderHealthy volunteers can take part
- Conditions the study is for
- Behavior Change Interventions
- What is being tested?
- Access to a trained ChatGPT
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- 1 Dec 2024to 31 Mar 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- Aged ≥65 years;
- Possession of a Hong Kong ID;
- Able to speak and comprehend Cantonese;
- Have a smartphone with internet access;
- Have not taken SIV for the approaching flu season.
Who cannot join
- With diagnosis of cognitive impairment or dementia;
- Either blindness or deafness;
- With known contraindications to the SIV as indicated by the Hong Kong Centre for Health Protection
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
In this project, we will train a ChatGPT to provide real-time answers to questions related to the SIV for older adults in Hong Kong.
This study aims to evaluate the usability, acceptability, and preliminary effectiveness of the ChatGPT among 50 community-living people aged 65 years and above in Hong Kong.
Read more
The primary objectives are to evaluate the usability and acceptability (including the extent of usage and subjective experiences of behavioural, cognitive, and affective engagement) of the ChatGPT at the end of the 4-week intervention period (T1).
The secondary objectives are to evaluate the following conditions measured at T1, as compared to those measured at baseline (T0):
- Self-reported uptake of SIV in the past month.
- Changes in behavioural intention to receive SIV for the approaching flu season.
- Changes in knowledge and attitudes related to SIV.
- Conditions
- Behavior Change Interventions
- Being tested
- Access to a trained ChatGPT
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Access to a trained ChatGPTBehavioural
Participants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions.
| Study group | Role | What they receive |
|---|---|---|
| ChatGPT group | Experimental | Participants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions. Receives: Behavioral: Access to a trained ChatGPT |
What is being measured
The primary outcome is the main question the study is designed to answer.
Perceived usability
Perceived usability assessed by the validated Chinese version of the 10-item Perceived Usability Scale (SUS)
Measured: 1 month
Extent of usage documented by the ChatGPT
Extent of usage documented by the ChatGPT
Measured: 1 month
Subjective experiences related to behavioural, cognitive, and affective engagement
Subjective experiences related to behavioural, cognitive, and affective engagement measured by the validated Twente Engagement with eHealth Technologies Scale (TWEETS)
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Nov 2024
- Study start1 Dec 2024 (estimated)
- Primary completion31 Mar 2025 (estimated)
- Study completion31 Mar 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Behavior Change InterventionsStudies of the same condition, open and under way.
- More trials run by Chinese University of Hong KongThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Chinese University of Hong Kong
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Zixin Wang, Chinese University of Hong Kong
- Investigators
- Zixin Wang, PhD, Principal investigator, Chinese University of Hong Kong
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06679647
- Sponsor's protocol ID
- SIV_ChatGPT
- Status last verified
- Nov 2024
- First submitted
- 6 Nov 2024
- Last updated
- 7 Nov 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Wang Z, Tsang TH, Yu FY, Fang Y, Chen S, Sun F, Mo PKH, Wong KC. Effectiveness, Usability, and Acceptability of ChatGPT With Retrieval-Augmented Generation (SIV-ChatGPT) in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults: Quasi-Experimental Study. J Med Internet Res. 2025 Sep 8;27:e76849. doi: 10.2196/76849.
PubMed 40921067
Study at a glance
From the registry record, last updated by the sponsor on 7 Nov 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acceptability, Usability and Preliminary Effectiveness of ChatGPT in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults in Hong Kong
- ClinicalTrials.gov ID
- NCT06679647
- Acronym / sponsor ID
- SIV_ChatGPT
- Conditions
- Behavior Change Interventions
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Chinese University of Hong KongUniversity, hospital or other
- Study start
- 1 Dec 2024 (estimated)
- Primary completion
- 31 Mar 2025 (estimated)
- Study completion
- 31 Mar 2025 (estimated)
- First posted
- 7 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this project, we will train a ChatGPT to provide real-time answers to questions related to the SIV for older adults in Hong Kong.
This study aims to evaluate the usability, acceptability, and preliminary effectiveness of the ChatGPT among 50 community-living people aged 65 years and above in Hong Kong.
The primary objectives are to evaluate the usability and acceptability (including the extent of usage and subjective experiences of behavioural, cognitive, and affective engagement) of the ChatGPT at the end of the 4-week intervention period (T1).
The secondary objectives are to evaluate the following conditions measured at T1, as compared to those measured at baseline (T0):
- Self-reported uptake of SIV in the past month.
- Changes in behavioural intention to receive SIV for the approaching flu season.
- Changes in knowledge and attitudes related to SIV.
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| ChatGPT group | Experimental | Behavioral: Access to a trained ChatGPTParticipants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (5 listed)
- Aged ≥65 years;
- Possession of a Hong Kong ID;
- Able to speak and comprehend Cantonese;
- Have a smartphone with internet access;
- Have not taken SIV for the approaching flu season.
Key exclusion criteria (3 listed)
- With diagnosis of cognitive impairment or dementia;
- Either blindness or deafness;
- With known contraindications to the SIV as indicated by the Hong Kong Centre for Health Protection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Access to a trained ChatGPTParticipants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions. | Behavioural | ChatGPT group |
Primary outcome
Perceived usability
Time frame: 1 month
Perceived usability assessed by the validated Chinese version of the 10-item Perceived Usability Scale (SUS)
Extent of usage documented by the ChatGPT
Time frame: 1 month
Extent of usage documented by the ChatGPT
Subjective experiences related to behavioural, cognitive, and affective engagement
Time frame: 1 month
Subjective experiences related to behavioural, cognitive, and affective engagement measured by the validated Twente Engagement with eHealth Technologies Scale (TWEETS)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Nov 2024.
- Derived from this study: PubMed 40921067Wang Z, Tsang TH, Yu FY, Fang Y, Chen S, Sun F, Mo PKH, Wong KC. Effectiveness, Usability, and Acceptability of ChatGPT With Retrieval-Augmented Generation (SIV-ChatGPT) in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults: Quasi-Experimental Study. J Med Internet Res. 2025 Sep 8;27:e76849. doi: 10.2196/76849.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Zixin Wang, PhD principal investigator
Chinese University of Hong Kong
Questions about this trial
What is this clinical trial studying?
A study testing Access to a trained ChatGPT in people with Behavior Change Interventions, run by Chinese University of Hong Kong.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Nov 2024. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Zixin Wang, PhD (+852 22528740, wangzx@cuhk.edu.hk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Perceived usability (time frame: 1 month). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06679647, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Nov 2024.