H PyloriNCT06632210
Psychological Effects of H Pylori Associated Gastritis
An observational study of H Pylori, run by Assiut University.
Trial summary
The goals of this study 1. Explore association between psychological factors and Hpylori associated gastritis. 2. Assess prevalence and severity of psychology symptoms among patients with H pylori associated gastritis and their effects on their life. 3. Examine relation between demographic and clinical variables . 4. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- H Pylori
- How many people
- 130 participants
- Where
- No sites listed yet
- Study dates
- 22 Mar 2026to 22 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: * all patients with H.Pylori associated gastritis that diagnosed by endoscopy. * patients diagnosed by detection of H.Pylori Ag in stool
Who may be able to join
- all patients with H.Pylori associated gastritis that diagnosed by endoscopy.
- patients diagnosed by detection of H.Pylori Ag in stool
Who cannot join
- patients did not take antibiotics within last 2 weeks
- patients did not take PPI within last 1 month
- patients not with acute massive GITbleeding.
- patients without eradication of H.Pylor
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Psychological Effects of Helicopter Pylori Associated Gastritis in Patients Attending Assiut University Hospitals
The goals of this study
- Explore association between psychological factors and Hpylori associated gastritis.
- Assess prevalence and severity of psychology symptoms among patients with H pylori associated gastritis and their effects on their life.
- Examine relation between demographic and clinical variables .
- Effect of eradication of H pylori on psychological status of patients.
Read the detailed description
One of the most prevalant chronic bacterial illness affecting people is it H.plyori infection. it affects at least 50% of people worldwide . it is a human gastrointestinal infection which is believed to be blammed for a number of gastric illness from chronic gastritis up to gastric cancer.
numerous literature data suggest there is strong relation of anxiety disorders, stress or depression to somatic symptoms and this relation can undergo potentialization in case of appearance of pathogenic factors like helicobacter pylori infection , this relation can confirmed with many scientific reports , with the common use of antidepressants and anxiety relieving drugs in duodenal ulcer disease therapy.
The close relationship of gastrointestinal function with brain function and the mental status is known as (gut brain axis).
it has been reported that emotional factors induce changes in gastric physiology that physiological stress induces personality dependant gastric acid secretion changes and avariety of alterations in gastric motility.
. the effect of numerous stress factors which injury mucosa of stomach and modify immunity of the patient so that the patient become more sensitive to be infected with H. Pylori and infection become more aggressive and lead to manifestation of gastritis , duodenitis and gastric ulcer disease.
mental stress is considered a major pathogenic factor for peptic ulcers and it is associated with increasing prevalence of gastric ulcersin patients is with or without H.pyloriinfection.
another study revealed that depression is associated with food related symptoms as nausea and vomiting ,similarly it was showing that gastric information lead to an anxiety and depression like behaviors via neuroendocrine pathways in female not male.
so the investigetors conducted this observational study to determine the most common physiological effect is of H.pylori associated gastritis in patients attending Assiut university hospitals and How to deal with it to improve quality of life.
- Conditions
- H Pylori
What is being measured
The primary outcome is the main question the study is designed to answer.
The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .
The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .
Measured: 2024
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Oct 2024
- Study start22 Mar 2026 (estimated)
- Primary completion22 Sep 2026 (estimated)
- Study completion22 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for H PyloriStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 130 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ashraf khalifa Darweesh Desokey, Assiut University
- Investigators
- Nabila fayeg Amen, Professor, Study director, Assiut UniversityMohammed Abozaid Ali, Doctor, Study director, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06632210
- Sponsor's protocol ID
- H pylori associated gastritis
- Status last verified
- Dec 2025
- First submitted
- 30 Sep 2024
- Last updated
- 2 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Psychological Effects of Helicopter Pylori Associated Gastritis in Patients Attending Assiut University Hospitals
- ClinicalTrials.gov ID
- NCT06632210
- Acronym / sponsor ID
- H pylori associated gastritis
- Conditions
- H Pylori
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 130 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 22 Mar 2026 (estimated)
- Primary completion
- 22 Sep 2026 (estimated)
- Study completion
- 22 Dec 2026 (estimated)
- First posted
- 9 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goals of this study
- Explore association between psychological factors and Hpylori associated gastritis.
- Assess prevalence and severity of psychology symptoms among patients with H pylori associated gastritis and their effects on their life.
- Examine relation between demographic and clinical variables .
- Effect of eradication of H pylori on psychological status of patients.
Detailed description
One of the most prevalant chronic bacterial illness affecting people is it H.plyori infection. it affects at least 50% of people worldwide . it is a human gastrointestinal infection which is believed to be blammed for a number of gastric illness from chronic gastritis up to gastric cancer.
numerous literature data suggest there is strong relation of anxiety disorders, stress or depression to somatic symptoms and this relation can undergo potentialization in case of appearance of pathogenic factors like helicobacter pylori infection , this relation can confirmed with many scientific reports , with the common use of antidepressants and anxiety relieving drugs in duodenal ulcer disease therapy.
The close relationship of gastrointestinal function with brain function and the mental status is known as (gut brain axis).
it has been reported that emotional factors induce changes in gastric physiology that physiological stress induces personality dependant gastric acid secretion changes and avariety of alterations in gastric motility.
. the effect of numerous stress factors which injury mucosa of stomach and modify immunity of the patient so that the patient become more sensitive to be infected with H. Pylori and infection become more aggressive and lead to manifestation of gastritis , duodenitis and gastric ulcer disease.
mental stress is considered a major pathogenic factor for peptic ulcers and it is associated with increasing prevalence of gastric ulcersin patients is with or without H.pyloriinfection.
another study revealed that depression is associated with food related symptoms as nausea and vomiting ,similarly it was showing that gastric information lead to an anxiety and depression like behaviors via neuroendocrine pathways in female not male.
so the investigetors conducted this observational study to determine the most common physiological effect is of H.pylori associated gastritis in patients attending Assiut university hospitals and How to deal with it to improve quality of life.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- * all patients with H.Pylori associated gastritis that diagnosed by endoscopy. * patients diagnosed by detection of H.Pylori Ag in stool
Key inclusion criteria (2 listed)
- all patients with H.Pylori associated gastritis that diagnosed by endoscopy.
- patients diagnosed by detection of H.Pylori Ag in stool
Key exclusion criteria (4 listed)
- patients did not take antibiotics within last 2 weeks
- patients did not take PPI within last 1 month
- patients not with acute massive GITbleeding.
- patients without eradication of H.Pylor
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .
Time frame: 2024
The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis .
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jan 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nabila fayeg Amen, Professor study director
Assiut University
Mohammed Abozaid Ali, Doctor study director
Assiut University
Questions about this trial
What is this clinical trial studying?
An observational study of H Pylori, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 2 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ashraf khalifa Darweesh Desokey Al deep, Master (01018479784, ashrafkhalifaaldeep@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The aim of this observational study is to Explore correlation between psychological factors and H.Pylori associated gastritis . (time frame: 2024). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jan 2026.