Geriatric PatientsNCT06610292
Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients
A study testing Pharmacist-led medication reconciliation services in people with Geriatric Patients and Medication Reconcilitation Upon Hospital Admission, run by University of Jordan at 1 site in Jordan.
Trial summary
This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Geriatric Patients, Medication Reconcilitation Upon Hospital Admission, Medication Reconciliation At Discharge
- What is being tested?
- Pharmacist-led medication reconciliation services
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 128 participants
- Where
- 1 siteJordan
- Study dates
- 24 Jun 2018to 13 Oct 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Who may be able to join
- Newly admitted patient within no more than 24 hours and anticipated to stay in the hospital for more than 48 hours.
- Geriatrics patients defined as those aged (≥65 years) (Orimo et al., 2006).
- Prescribed at least one chronic medication prior to the study admission.
Who cannot join
- Patient admitted to the critical care or isolation units or in unconscious or comatose states.
- Patients if they were discharged against medical advice.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients At a Leading Military Hospital in Jordan
This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan.
Read the detailed description
A four-month randomized controlled trial was conducted at King Hussein Medical Hospital (KHMH), one of the Royal Military Medical Services (RMS) tertiary hospitals located in central Amman. During the study period, 128 patients were selected using convenience sampling. Later, medication histories were compared between pre-admission and admission records to obtain the Best Possible Medication History (BPMH) and identify medication discrepancies, which were categorized as either intentional (documentation errors) or unintentional discrepancies.
The already selected patients were randomly allocated into two groups (intervention and control groups). Then, Pharmacist-led medication reconciliation services were provided to the intervention group and standard care was provided to the control group. Also at discharge the number of medication discrepancies was documented. Linear regression analysis was performed to assess risk factors associated with the occurrence of unintentional discrepancies.
Within 30 days post-discharge, patients were assessed for any hospital re-admissions, emergency department visits and medication-related side effects.
- Conditions
- Geriatric Patients, Medication Reconcilitation Upon Hospital Admission, Medication Reconciliation At Discharge, Pharmacist-led Medication Reconciliation
- Being tested
- Pharmacist-led medication reconciliation services
- Keywords
- Medication reconciliation, Geriatrics, Geriatric patients, Jordan, Tertiary military hospital, Pharmacist-led medication reconciliation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pharmacist-led medication reconciliation servicesOther
Upon admission, information about patients Best Possible Medication History (BPMH) was extracted. Information on current medications, both regular and as-needed, was also recorded. All data were cross-referenced with the electronic records and verified through patients or caregivers interviews to create a comprehensive medication list.
Then, comparison was conducted between standard care medication list and Pharmacist-led medication reconciliation list to identify any possible medication discrepancies. Also, during hospital stay and upon discharge emerging medication discrepancies were assessed and resolved.
Moreover, the impacts on healthcare resources utilization within 30 days post-discharge was measured. This includes evaluating hospital re-admissions, emergency department visits, and the occurrence of any adverse drug events (ADEs).
| Study group | Role | What they receive |
|---|---|---|
| Control group | No intervention | Patients did not receive Pharmacist-led medication reconciliation services |
| Intervention group | Experimental | Patients received Pharmacist-led medication reconciliation services Receives: Other: Pharmacist-led medication reconciliation services |
What is being measured
The primary outcome is the main question the study is designed to answer.
Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies.
Linear regression analysis was performed to assess risk factors associated with the occurrence of medication discrepancies in elderly patients.
Measured: Up to 20 weeks
Analysis of the effects of Pharmacist-led medication reconciliation services on resolving medication discrepancies upon discharge
Number of resolved medication discrepancies was documented upon discharge after providing pharmacist-led medication reconciliation services.
Measured: Up to 16 weeks
Evaluating the impacts of Pharmacist-led medication reconciliation services on hospital re-admissions within 30 days of discharge
Elderly patients were assessed for number of hospital re-admissions within 30 days of discharge at control and intervention groups.
Measured: Up to 20 weeks
Evaluating the impacts of Pharmacist-led medication reconciliation services on emergency department visits within 30 days of discharge
Elderly patients were assessed for number of emergency department visits within 30 days of discharge at control and intervention groups.
Measured: Up to 20 weeks
Evaluating the impacts of Pharmacist-led medication reconciliation services on medications side effects within 30 days of discharge
Elderly patients were assessed for incidence of medications side effects within 30 days of discharge at control and intervention groups.
Measured: Up to 20 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Sep 2024
- Study start24 Jun 2018
- Primary completion13 Oct 2018
- Study completion13 Oct 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Geriatric PatientsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Care provider
- Enrolment
- 128 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Jordan
- Sponsor type
- University, hospital or other
- Collaborators
- Jordanian Royal Medical Services, Royal Medical Services, Jordanian Armed Forces
- Responsible party
- Principal investigator, Majed Shafaamri, University of Jordan
- Investigators
- Eman A Hammad, Principal investigator, Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, University of Jordan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06610292
- Sponsor's protocol ID
- 6/2018
- Status last verified
- Sep 2024
- First submitted
- 17 Sep 2024
- Last updated
- 24 Sep 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients At a Leading Military Hospital in Jordan
- ClinicalTrials.gov ID
- NCT06610292
- Acronym / sponsor ID
- 6/2018
- Conditions
- Geriatric Patients, Medication Reconcilitation Upon Hospital Admission, Medication Reconciliation At Discharge, Pharmacist-led Medication Reconciliation
- Keywords
- Medication reconciliation, Geriatrics, Geriatric patients, Jordan, Tertiary military hospital, Pharmacist-led medication reconciliation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 128 participants (actual)
- Lead sponsor
- University of JordanUniversity, hospital or other
- Collaborators
- Jordanian Royal Medical Services, Royal Medical Services, Jordanian Armed Forces
- Study start
- 24 Jun 2018 (actual)
- Primary completion
- 13 Oct 2018 (actual)
- Study completion
- 13 Oct 2018 (actual)
- First posted
- 24 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan.
Detailed description
A four-month randomized controlled trial was conducted at King Hussein Medical Hospital (KHMH), one of the Royal Military Medical Services (RMS) tertiary hospitals located in central Amman. During the study period, 128 patients were selected using convenience sampling. Later, medication histories were compared between pre-admission and admission records to obtain the Best Possible Medication History (BPMH) and identify medication discrepancies, which were categorized as either intentional (documentation errors) or unintentional discrepancies.
The already selected patients were randomly allocated into two groups (intervention and control groups). Then, Pharmacist-led medication reconciliation services were provided to the intervention group and standard care was provided to the control group. Also at discharge the number of medication discrepancies was documented. Linear regression analysis was performed to assess risk factors associated with the occurrence of unintentional discrepancies.
Within 30 days post-discharge, patients were assessed for any hospital re-admissions, emergency department visits and medication-related side effects.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (care provider)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control group | No intervention | –Patients did not receive Pharmacist-led medication reconciliation services |
| Intervention group | Experimental | Other: Pharmacist-led medication reconciliation servicesPatients received Pharmacist-led medication reconciliation services |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
Key inclusion criteria (3 listed)
- Newly admitted patient within no more than 24 hours and anticipated to stay in the hospital for more than 48 hours.
- Geriatrics patients defined as those aged (≥65 years) (Orimo et al., 2006).
- Prescribed at least one chronic medication prior to the study admission.
Key exclusion criteria (2 listed)
- Patient admitted to the critical care or isolation units or in unconscious or comatose states.
- Patients if they were discharged against medical advice.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pharmacist-led medication reconciliation servicesUpon admission, information about patients Best Possible Medication History (BPMH) was extracted. Information on current medications, both regular and as-needed, was also recorded. All data were cross-referenced with the electronic records and verified through patients or caregivers interviews to create a comprehensive medication list. Then, comparison was conducted between standard care medication list and Pharmacist-led medication reconciliation list to identify any possible medication discrepancies. Also, during hospital stay and upon discharge emerging medication discrepancies were assessed and resolved. Moreover, the impacts on healthcare resources utilization within 30 days post-discharge was measured. This includes evaluating hospital re-admissions, emergency department visits, and the occurrence of any adverse drug events (ADEs). | Other | Intervention group |
Primary outcome
Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies.
Time frame: Up to 20 weeks
Linear regression analysis was performed to assess risk factors associated with the occurrence of medication discrepancies in elderly patients.
Analysis of the effects of Pharmacist-led medication reconciliation services on resolving medication discrepancies upon discharge
Time frame: Up to 16 weeks
Number of resolved medication discrepancies was documented upon discharge after providing pharmacist-led medication reconciliation services.
Evaluating the impacts of Pharmacist-led medication reconciliation services on hospital re-admissions within 30 days of discharge
Time frame: Up to 20 weeks
Elderly patients were assessed for number of hospital re-admissions within 30 days of discharge at control and intervention groups.
Evaluating the impacts of Pharmacist-led medication reconciliation services on emergency department visits within 30 days of discharge
Time frame: Up to 20 weeks
Elderly patients were assessed for number of emergency department visits within 30 days of discharge at control and intervention groups.
Evaluating the impacts of Pharmacist-led medication reconciliation services on medications side effects within 30 days of discharge
Time frame: Up to 20 weeks
Elderly patients were assessed for incidence of medications side effects within 30 days of discharge at control and intervention groups.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2024.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Eman A Hammad principal investigator
Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, University of Jordan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pharmacist-led medication reconciliation services in people with Geriatric Patients and Medication Reconcilitation Upon Hospital Admission, run by University of Jordan at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Sep 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies. (time frame: Up to 20 weeks). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2024.