Sleep DeprivationNCT06606626
Sleep and Resistance Exercise
A study testing Sleep deprivation and Sleep place in people with Sleep Deprivation, run by University of Alcala at 1 site in Spain.
Trial summary
Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood. Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Sleep Deprivation
- What is being tested?
- Sleep deprivation and Sleep place
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 28 participants
- Where
- 1 siteSpain
- Study dates
- 7 Jan 2024to 30 Jan 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age between 18 and 35 years.
- Body Mass Index (BMI) \< 25 kg/m².
- Resistance-trained individuals (more than 2 years of structured training).
- Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
- Participants must be able to perform the tests described in the following section.
Who cannot join
- History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
- Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
- Sedentary habits (less than 150 minutes/week of moderate exercise).
- Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
- Engaging in strenuous exercise within 48 hours prior to the tests.
- Failure to replicate the same food intake on both experimental days.
- Consumption of caffeine or any other stimulant the day before the tests.
Trial locations and contacts
1 site in 1 country.
Spain1 site
Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá
Alcalá de Henares, Madrid, 28805
About this study
Official title: Relationship Between Sleep Time and Quality With the Production of Force, Power, and Muscular Endurance.
Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood. Furthermore, the interaction between complete and partial sleep deprivation over one night and sleeping the usual hours for each person remains unclear.
Objectives: The aim of this study is to evaluate the effects of sleep deprivation on the production of strength, power, and muscular endurance according to sex (men vs. women) and type of exercise (bench press vs. squat). Additionally, the study will analyze the effects of sleep deprivation on perceived fatigue, mood, dietary habits, electrical activity, resting metabolic rate (RMR), and maximal fat oxidation (MFO).
- Conditions
- Sleep Deprivation
- Being tested
- Sleep deprivation, Sleep place
- Medical subject headings
- Sleep Deprivation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sleep deprivationBehavioural
Partial (4h) or total (0h) sleep deprivation
Sleep placeBehavioural
8h sleep at home or in the laboratory
| Study group | Role | What they receive |
|---|---|---|
| 8h Sleep (at home) | Placebo comparator | Participants sleep 8h at home Receives: Behavioral: Sleep place |
| 8h Sleep (Laboratory) | Experimental | Participants sleep 8h in the lab Receives: Behavioral: Sleep deprivation; Behavioral: Sleep place |
| 4h Sleep (Laboratory) | Experimental | Participants sleep 4h in the laboratory Receives: Behavioral: Sleep deprivation |
| 0h Sleep (Laboratory) | Experimental | Participants sleep 0h in the laboratory Receives: Behavioral: Sleep deprivation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean velocity at different %1RM
Measuring bar mean velocity desplacement during bench press and back squat exercises.
Measured: Through study completion, an average of 4 weeks
Peak velocity at different %1RM
Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.
Measured: Through study completion, an average of 4 weeks
Mean power output at different %1RM
Measuring during bench press and back squat exercises.
Measured: Through study completion, an average of 4 weeks
Peak power output and time to reach peak power output at different %1RM
Measuring during bench press and back squat exercises.
Measured: Through study completion, an average of 4 weeks
Number of repetitions performed at 65%1RM until task failure
In bench press and back squat exercises
Measured: Through study completion, an average of 4 weeks
Bar velocity deplacement performed in 1 set at 65%1RM until task failure
In bench press and back squat exercises
Measured: Through study completion, an average of 4 weeks
Power output generated in 1 set at 65%1RM until task failure
In bench press and back squat exercise
Measured: Through study completion, an average of 4 weeks
Resting Metabolic Rate (RMR)
Kcal at rest measuring a metabolic chart
Measured: Through study completion, an average of 4 weeks
Maximal Fat Oxidation Rate
g/min using a metabolic chart
Measured: Through study completion, an average of 4 weeks
Secondary outcomes (5)
Physical activity (METs-min/wk)
Using IPAQ
Measured: Before each trial, during the 4 weeks
Dietary habits (g/kg of macronutrients)
Using a 24-total recall
Measured: Before each trial, during the 4 weeks
Fat mass
Using electrical bioimpedance (kg and % of body mass)
Measured: Through study completion, an average of 4 weeks
Fat-free mass
Using electrical bioimpedance (kg and % of body mass)
Measured: Through study completion, an average of 4 weeks
Mood state (tension, depression, anger, vigor, fatigue and confusion)
Participants graded a set of 29 items related to the mood on a Likert scale from 0 (not at all) to 4 (extremely) in reply to the question;How do you feel at this moment?; to assess six scales: tension, depression, anger, vigor, fatigue and confusion.
Measured: Through study completion, an average of 4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2024
- Study start7 Jan 2024
- Primary completion30 Jan 2025
- Study completion30 Jan 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sleep DeprivationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 28 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Alcala
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Alberto Pérez-López, University of Alcala
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06606626
- Sponsor's protocol ID
- CEID/2023/6/119
- Status last verified
- May 2025
- First submitted
- 9 Sep 2024
- Last updated
- 25 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 25 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Sleep Time and Quality With the Production of Force, Power, and Muscular Endurance.
- ClinicalTrials.gov ID
- NCT06606626
- Acronym / sponsor ID
- CEID/2023/6/119
- Conditions
- Sleep Deprivation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 28 participants (actual)
- Lead sponsor
- University of AlcalaUniversity, hospital or other
- Study start
- 7 Jan 2024 (actual)
- Primary completion
- 30 Jan 2025 (actual)
- Study completion
- 30 Jan 2025 (actual)
- First posted
- 23 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood. Furthermore, the interaction between complete and partial sleep deprivation over one night and sleeping the usual hours for each person remains unclear.
Objectives: The aim of this study is to evaluate the effects of sleep deprivation on the production of strength, power, and muscular endurance according to sex (men vs. women) and type of exercise (bench press vs. squat). Additionally, the study will analyze the effects of sleep deprivation on perceived fatigue, mood, dietary habits, electrical activity, resting metabolic rate (RMR), and maximal fat oxidation (MFO).
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind (participant, investigator)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| 8h Sleep (at home) | Placebo comparator | Behavioral: Sleep placeParticipants sleep 8h at home |
| 8h Sleep (Laboratory) | Experimental | Behavioral: Sleep deprivation, Behavioral: Sleep placeParticipants sleep 8h in the lab |
| 4h Sleep (Laboratory) | Experimental | Behavioral: Sleep deprivationParticipants sleep 4h in the laboratory |
| 0h Sleep (Laboratory) | Experimental | Behavioral: Sleep deprivationParticipants sleep 0h in the laboratory |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age between 18 and 35 years.
- Body Mass Index (BMI) \< 25 kg/m².
- Resistance-trained individuals (more than 2 years of structured training).
- Healthy men and women without neurological, cardiometabolic, immunological, or physical conditions that prevent them from exercising.
- Participants must be able to perform the tests described in the following section.
Key exclusion criteria (7 listed)
- History of neuromuscular diseases, heart disease, or conditions that may affect liver or muscle metabolism.
- Use of drugs, stimulants, or sports supplements that could interfere with the dietary supplement used in the study.
- Sedentary habits (less than 150 minutes/week of moderate exercise).
- Having undergone prolonged periods of physical inactivity in the 6 months prior to the study.
- Engaging in strenuous exercise within 48 hours prior to the tests.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sleep deprivationPartial (4h) or total (0h) sleep deprivation | Behavioural | 0h Sleep (Laboratory), 4h Sleep (Laboratory), 8h Sleep (Laboratory) |
| Sleep place8h sleep at home or in the laboratory | Behavioural | 8h Sleep (Laboratory), 8h Sleep (at home) |
Primary outcome
Mean velocity at different %1RM
Time frame: Through study completion, an average of 4 weeks
Measuring bar mean velocity desplacement during bench press and back squat exercises.
Peak velocity at different %1RM
Time frame: Through study completion, an average of 4 weeks
Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises.
Mean power output at different %1RM
Time frame: Through study completion, an average of 4 weeks
Measuring during bench press and back squat exercises.
Peak power output and time to reach peak power output at different %1RM
Time frame: Through study completion, an average of 4 weeks
Measuring during bench press and back squat exercises.
Number of repetitions performed at 65%1RM until task failure
Time frame: Through study completion, an average of 4 weeks
In bench press and back squat exercises
Bar velocity deplacement performed in 1 set at 65%1RM until task failure
Time frame: Through study completion, an average of 4 weeks
In bench press and back squat exercises
Power output generated in 1 set at 65%1RM until task failure
Time frame: Through study completion, an average of 4 weeks
In bench press and back squat exercise
Resting Metabolic Rate (RMR)
Time frame: Through study completion, an average of 4 weeks
Kcal at rest measuring a metabolic chart
Maximal Fat Oxidation Rate
Time frame: Through study completion, an average of 4 weeks
g/min using a metabolic chart
5 secondary outcomes
Physical activity (METs-min/wk)
Time frame: Before each trial, during the 4 weeks
Dietary habits (g/kg of macronutrients)
Time frame: Before each trial, during the 4 weeks
Fat mass
Time frame: Through study completion, an average of 4 weeks
Fat-free mass
Time frame: Through study completion, an average of 4 weeks
Mood state (tension, depression, anger, vigor, fatigue and confusion)
Time frame: Through study completion, an average of 4 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 May 2025.
- Individual participant dataSharing planned: Yes
Related trials for Sleep Deprivation
Not yet recruiting
Study on the Mechanism of Central Obesity Induced by Sleep Restriction and the Therapeutic Effect of n-3 Polyunsaturated Fatty Acid: a Randomized, Double-blind, Placebo-controlled Trial (COSPA Study)
Sleep Deprivation
Recruiting
Sleep and Circadian Rhythm Intervention in ICU
ICU Hospitalization, Circadian Rhythm
Recruiting
Effect of Sleep Extension in Prevention to Sleep Deprivation
Healthy
Not yet recruiting
Evolution of Sleep in Intensive Care Unit Patients
ICU, Sleep Deprivation
Active, not recruiting
The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sleep deprivation and Sleep place in people with Sleep Deprivation, run by University of Alcala at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean velocity at different %1RM (time frame: Through study completion, an average of 4 weeks). The study lists 9 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 May 2025; AzTrials last refreshed its copy on 28 Oct 2026.