Nasotracheal IntubationNCT06605989
Nostril Side on Epistaxis
A study testing Nasotracheal intubation in people with Nasotracheal Intubation, run by Seoul National University Hospital at 2 sites in South Korea.
Trial summary
The purpose of the study is to investigate the effect of the nostril side on epistaxis during nasotracheal intubation. Read more about this study
- Who is it for?
- Ages 19 years and older
- Conditions the study is for
- Nasotracheal Intubation
- What is being tested?
- Nasotracheal intubation
- Type of treatment
- Pill or oral medicine, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 208 participants
- Where
- 2 sitesSouth Korea
- Study dates
- 26 Sep 2024to 28 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 19 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- adult patients requiring nasotracheal intubation for elective surgery
Who cannot join
- refuse to participate in the study
- severe deformity in the nose
- current severe epistaxis
- cannot insert the tube into a specific nostril side due to any reason
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
South Korea2 sites, 2 recruiting
- Recruiting
Seoul Metropolitan Government Seoul National University Boramae Medical Center
Seoul, Dongjak-gu, 07061
Jung-Man Lee, M.D.,Ph.D., +82-2-870-2513, jungman007@gmail.com
Jung-Man Lee, M.D.,Ph.D.
- Recruiting
Gangnam Severance Hospital
Seoul, Gangnam-gu, 06273
Jiwon Lee, M.D.,Ph.D., +82-10-5279-8275, belief705@gmail.com
Jiwon Lee, M.D.,Ph.D.
About this study
Official title: The Effect of Nostril Side on Epistaxis During Nasotracheal Intubation
The purpose of the study is to investigate the effect of the nostril side on epistaxis during nasotracheal intubation.
Read the detailed description
This prospective randomized controlled study was approved by the IRB of our institute.
Patients requiring nasotracheal intubation will be screened for eligibility for the study. Then, patients will be randomized to one of two groups; (Group I: tube will be inserted through the left nostril and advanced into the oral cavity / Group II: tube will be inserted through the right nostril and advanced into the oral cavity). After induction of anesthesia and muscle relaxation, the preformed nasal RAE (Ring-Adair-Elwyn) tube will be inserted via the nostril, which is assigned to each patient according to the group, approximately 3-4 cm. Next, an anesthesiologist will advance the tube into the oral cavity. After the tube is placed in the oral cavity, the anesthesiologist will perform nasotracheal intubation with Magill forceps. After that, an investigator will check the occurrence of epistaxis due to nasotracheal intubation and its severity with a fiberoptic bronchoscope. After obtaining all data, investigators will analyze the incidence of epistaxis and its severity between the two groups.
- Conditions
- Nasotracheal Intubation
- Being tested
- Nasotracheal intubation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nasotracheal intubationProcedure or surgery
For nasotracheal intubation, the nasal RAE tube will be first inserted through the left nostril for patients in the left nostril side arm. For nasotracheal intubation, the nasal RAE tube will be first inserted through the right nostril for patients in the right nostril side arm.
| Study group | Role | What they receive |
|---|---|---|
| left nostril side | Experimental | For nasotracheal intubation, the nasal RAE tube will be inserted through the left nostril and advanced into the oral cavity. Receives: Procedure: Nasotracheal intubation |
| right nostril side | Experimental | For nasotracheal intubation, the nasal RAE tube will be inserted through the right nostril and advanced into the oral cavity. Receives: Procedure: Nasotracheal intubation |
What is being measured
The primary outcome is the main question the study is designed to answer.
epistaxis
epistaxis due to nasotracheal intubation
Measured: during nasotracheal intubation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Sep 2024
- Study start26 Sep 2024
- Primary completion28 Feb 2026 (estimated)
- Study completion28 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Nasotracheal IntubationStudies of the same condition, open and under way.
- More trials run by Seoul National University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Care provider
- Enrolment
- 208 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Seoul National University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- SMG-SNU Boramae Medical Center
- Responsible party
- Sponsor
- Investigators
- Jung-Man Lee, M.D.,Ph.D., Principal investigator, Seoul National University College of Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06605989
- Sponsor's protocol ID
- 04-2024-0025
- Status last verified
- Sep 2025
- First submitted
- 18 Sep 2024
- Last updated
- 11 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Sanuki T, Hirokane M, Kotani J. Epistaxis during nasotracheal intubation: a comparison of nostril sides. J Oral Maxillofac Surg. 2010 Mar;68(3):618-21. doi: 10.1016/j.joms.2009.04.097. Epub 2009 Nov 22.
PubMed 19931965
Study at a glance
From the registry record, last updated by the sponsor on 11 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Nostril Side on Epistaxis During Nasotracheal Intubation
- ClinicalTrials.gov ID
- NCT06605989
- Acronym / sponsor ID
- 04-2024-0025
- Conditions
- Nasotracheal Intubation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 208 participants (estimated)
- Lead sponsor
- Seoul National University HospitalUniversity, hospital or other
- Collaborators
- SMG-SNU Boramae Medical Center
- Study start
- 26 Sep 2024 (actual)
- Primary completion
- 28 Feb 2026 (estimated)
- Study completion
- 28 Feb 2026 (estimated)
- First posted
- 20 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to investigate the effect of the nostril side on epistaxis during nasotracheal intubation.
Detailed description
This prospective randomized controlled study was approved by the IRB of our institute.
Patients requiring nasotracheal intubation will be screened for eligibility for the study. Then, patients will be randomized to one of two groups; (Group I: tube will be inserted through the left nostril and advanced into the oral cavity / Group II: tube will be inserted through the right nostril and advanced into the oral cavity). After induction of anesthesia and muscle relaxation, the preformed nasal RAE (Ring-Adair-Elwyn) tube will be inserted via the nostril, which is assigned to each patient according to the group, approximately 3-4 cm. Next, an anesthesiologist will advance the tube into the oral cavity. After the tube is placed in the oral cavity, the anesthesiologist will perform nasotracheal intubation with Magill forceps. After that, an investigator will check the occurrence of epistaxis due to nasotracheal intubation and its severity with a fiberoptic bronchoscope. After obtaining all data, investigators will analyze the incidence of epistaxis and its severity between the two groups.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, care provider)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| left nostril side | Experimental | Procedure: Nasotracheal intubationFor nasotracheal intubation, the nasal RAE tube will be inserted through the left nostril and advanced into the oral cavity. |
| right nostril side | Experimental | Procedure: Nasotracheal intubationFor nasotracheal intubation, the nasal RAE tube will be inserted through the right nostril and advanced into the oral cavity. |
Who may qualify
- Ages
- 19 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- adult patients requiring nasotracheal intubation for elective surgery
Key exclusion criteria (4 listed)
- refuse to participate in the study
- severe deformity in the nose
- current severe epistaxis
- cannot insert the tube into a specific nostril side due to any reason
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nasotracheal intubationFor nasotracheal intubation, the nasal RAE tube will be first inserted through the left nostril for patients in the left nostril side arm. For nasotracheal intubation, the nasal RAE tube will be first inserted through the right nostril for patients in the right nostril side arm. | Procedure or surgery | left nostril side, right nostril side |
Primary outcome
epistaxis
Time frame: during nasotracheal intubation
epistaxis due to nasotracheal intubation
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Feb 2026.
- Background: PubMed 19931965Sanuki T, Hirokane M, Kotani J. Epistaxis during nasotracheal intubation: a comparison of nostril sides. J Oral Maxillofac Surg. 2010 Mar;68(3):618-21. doi: 10.1016/j.joms.2009.04.097. Epub 2009 Nov 22.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jung-Man Lee, M.D.,Ph.D. principal investigator
Seoul National University College of Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nasotracheal intubation in people with Nasotracheal Intubation, run by Seoul National University Hospital at 2 sites in South Korea.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in South Korea. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jung-Man Lee, M.D., Ph.D. (+82-2-870-2513, jungman007@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
epistaxis (time frame: during nasotracheal intubation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06605989, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Feb 2026.