Chronic PainNCT06590181
Comparing the Effects of Yoga Nidra to Yoga Nidra With Pain Acceptance Intention and Motor Imagery on Pain Outcomes
A study testing Yoga Nidra, Yoga Nidra with Pain Acceptance Intention and Yoga Nidra with Pain Acceptance Intervention and Motor Imagery in people with Chronic Pain, run by University of Central Florida at 1 site in United States.
Trial summary
Yoga Nidra is a scripted mind-body intervention (MBI) that uses guided relaxation technique in a reproducible sequence of mechanisms that naturally produce a parasympathetic response. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Chronic Pain
- What is being tested?
- Yoga Nidra, Yoga Nidra with Pain Acceptance Intention and Yoga Nidra with Pain Acceptance Intervention and Motor Imagery
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteUnited States
- Study dates
- 12 Sep 2024to 29 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Chronic pain in the neck, low back, shoulder, hip, elbow, knee, wrist, or ankle that has lasted for over three months
- Pain intensity rated as 3/10 or higher in the past 24 hours (0=no pain, 10=worst pain imaginable)
Who cannot join
- non-English speaking
- systemic medical conditions that affect sensation (such as uncontrolled diabetes)
- History of surgery or fracture within the past six months
- any blood clotting disorders (such as hemophilia)
- any contraindication to the application of ice (blood pressure \> 140/90 mmHg, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise)
- Exceed pressure and heat sensory thresholds
- Unable to access internet or email
- Pregnant
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Central Florida
Orlando, Florida, 32816
About this study
Yoga Nidra is a scripted mind-body intervention (MBI) that uses guided relaxation technique in a reproducible sequence of mechanisms that naturally produce a parasympathetic response. This is a randomized controlled trial in which participants will be randomly assigned to one of three interventions: 1) yoga nidra (Yoga Nidra Script Basic), 2) yoga nidra with pain acceptance (Yoga Nidra Acceptance Intention), 3) yoga nidra with pain acceptance and Explicit Motor Imagery (Yoga Nidra Acceptance Intention and Visualization).
- Conditions
- Chronic Pain
- Being tested
- Yoga Nidra, Yoga Nidra with Pain Acceptance Intention, Yoga Nidra with Pain Acceptance Intervention and Motor Imagery
- Keywords
- chronic pain, meditation
- Medical subject headings
- Chronic Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Yoga NidraOther
This protocol is derived from The Origin and Clinical Relevance of Yoga Nidra (Pandi-Perumal, S. R. 2022)
Yoga Nidra with Pain Acceptance IntentionOther
Yoga Nidra with Pain Acceptance Intention
Yoga Nidra with Pain Acceptance Intervention and Motor ImageryOther
Yoga Nidra with Pain Acceptance Intervention and Motor Imagery
| Study group | Role | What they receive |
|---|---|---|
| Yoga Nidra | Experimental | This protocol is derived from The Origin and Clinical Relevance of Yoga Nidra (Pandi-Perumal, S. R. 2022) and is approximately 20 minutes total time. Receives: Other: Yoga Nidra |
| Yoga Nidra and Pain Acceptance Intention | Active comparator | Yoga Nidra plus a Pain Acceptance Intention. Receives: Other: Yoga Nidra with Pain Acceptance Intention |
| Yoga Nidra with Pain Acceptance Intervention and Motor Imagery | Active comparator | Yoga Nidra plus pain acceptance and motor imagery Receives: Other: Yoga Nidra with Pain Acceptance Intervention and Motor Imagery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pressure Pain Threshold
A computerized pressure algometer (AlgoMed, Ramat Yishai, Israel) with a 1 cm diameter rubber tip will be applied to the upper trapezius.
Measured: Pre/Post intervention, Day 1
Temporal Summation
Change in pain ratings during 10 heat pulses will be recorded.
Measured: Pre/Post intervention, Day 1
Conditioned Pain Modulation
Pressure pain threshold after a cold water immersion task.
Measured: Pre/Post intervention, Day 1
Heat Pain Threshold
Participants will report when comfortable heat becomes painful by pressing a button. Temperature in degrees Celsius will be recorded at threshold
Measured: Pre/Post intervention, Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Sep 2024
- Study start12 Sep 2024
- Primary completion29 Jul 2025
- Study completion29 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Central Florida
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abigail Wilson, University of Central Florida
- Investigators
- Abigail Anderson, PT, DPT, PhD, Principal investigator, University of Central Florida
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06590181
- Sponsor's protocol ID
- YN10
- Status last verified
- Dec 2024
- First submitted
- 29 Aug 2024
- Last updated
- 26 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparing the Effects of Yoga Nidra to Yoga Nidra With Pain Acceptance Intention and Motor Imagery on Pain Outcomes
- ClinicalTrials.gov ID
- NCT06590181
- Acronym / sponsor ID
- YN10
- Conditions
- Chronic Pain
- Keywords
- chronic pain, meditation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- University of Central FloridaUniversity, hospital or other
- Study start
- 12 Sep 2024 (actual)
- Primary completion
- 29 Jul 2025 (actual)
- Study completion
- 29 Jul 2025 (actual)
- First posted
- 19 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Yoga Nidra is a scripted mind-body intervention (MBI) that uses guided relaxation technique in a reproducible sequence of mechanisms that naturally produce a parasympathetic response. This is a randomized controlled trial in which participants will be randomly assigned to one of three interventions: 1) yoga nidra (Yoga Nidra Script Basic), 2) yoga nidra with pain acceptance (Yoga Nidra Acceptance Intention), 3) yoga nidra with pain acceptance and Explicit Motor Imagery (Yoga Nidra Acceptance Intention and Visualization).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Yoga Nidra | Experimental | Other: Yoga NidraThis protocol is derived from The Origin and Clinical Relevance of Yoga Nidra (Pandi-Perumal, S. R. 2022) and is approximately 20 minutes total time. |
| Yoga Nidra and Pain Acceptance Intention | Active comparator | Other: Yoga Nidra with Pain Acceptance IntentionYoga Nidra plus a Pain Acceptance Intention. |
| Yoga Nidra with Pain Acceptance Intervention and Motor Imagery | Active comparator | Other: Yoga Nidra with Pain Acceptance Intervention and Motor ImageryYoga Nidra plus pain acceptance and motor imagery |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Chronic pain in the neck, low back, shoulder, hip, elbow, knee, wrist, or ankle that has lasted for over three months
- Pain intensity rated as 3/10 or higher in the past 24 hours (0=no pain, 10=worst pain imaginable)
Key exclusion criteria (8 listed)
- non-English speaking
- systemic medical conditions that affect sensation (such as uncontrolled diabetes)
- History of surgery or fracture within the past six months
- any blood clotting disorders (such as hemophilia)
- any contraindication to the application of ice (blood pressure \> 140/90 mmHg, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Yoga NidraThis protocol is derived from The Origin and Clinical Relevance of Yoga Nidra (Pandi-Perumal, S. R. 2022) | Other | Yoga Nidra |
| Yoga Nidra with Pain Acceptance IntentionYoga Nidra with Pain Acceptance Intention | Other | Yoga Nidra and Pain Acceptance Intention |
| Yoga Nidra with Pain Acceptance Intervention and Motor ImageryYoga Nidra with Pain Acceptance Intervention and Motor Imagery | Other | Yoga Nidra with Pain Acceptance Intervention and Motor Imagery |
Primary outcome
Pressure Pain Threshold
Time frame: Pre/Post intervention, Day 1
A computerized pressure algometer (AlgoMed, Ramat Yishai, Israel) with a 1 cm diameter rubber tip will be applied to the upper trapezius.
Temporal Summation
Time frame: Pre/Post intervention, Day 1
Change in pain ratings during 10 heat pulses will be recorded.
Conditioned Pain Modulation
Time frame: Pre/Post intervention, Day 1
Pressure pain threshold after a cold water immersion task.
Heat Pain Threshold
Time frame: Pre/Post intervention, Day 1
Participants will report when comfortable heat becomes painful by pressing a button. Temperature in degrees Celsius will be recorded at threshold
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Abigail Anderson, PT, DPT, PhD principal investigator
University of Central Florida
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Yoga Nidra, Yoga Nidra with Pain Acceptance Intention and Yoga Nidra with Pain Acceptance Intervention and Motor Imagery in people with Chronic Pain, run by University of Central Florida at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 26 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pressure Pain Threshold (time frame: Pre/Post intervention, Day 1). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Aug 2026.