Advance Care PlanningJUMPNCT06538493
Jumpstarting Advance Care Planning With ANAI People
A study testing JUMPSTART-ANAI in people with Advance Care Planning, run by Southcentral Foundation at 1 site in United States.
Trial summary
The older Alaska Native/American Indian (ANAI) population is increasing at twice the rate of the general population with a higher burden of serious illness. Older ANAI adults with serious illness are half as likely to have advance directives (AD), indicating a need for improved access to and utilization of advance… Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Advance Care Planning
- What is being tested?
- JUMPSTART-ANAI
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 400 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Apr 2025to 30 May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 40 or older with a qualifying serious illness condition (e.g., COPD) OR Age 65 or older (regardless of diagnosis) AND Alaska Native and/or American Indian AND Empaneled to a primary care provider AND 2 or more to primary care in last 12 months AND No advance directives documented in electronic health record
Who cannot join
- Unable to provide informed consent AND/OR Not able to complete 30-minute study visit by phone, video call, or in person
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
John Trainor, PhD, MPH contact
United States1 site, 1 recruiting
- Recruiting
Southcentral Foundation
Anchorage, Alaska, 99508
Richard B Woodbury, MPH, rwoodbury@scf.cc
About this study
Official title: Jumpstarting Advance Care Planning With ANAI People in Primary Care
The older Alaska Native/American Indian (ANAI) population is increasing at twice the rate of the general population with a higher burden of serious illness. Older ANAI adults with serious illness are half as likely to have advance directives (AD), indicating a need for improved access to and utilization of advance care planning (ACP) to ensure that medical care aligns with the values, goals, and preferences of ANAI patients and their families throughout the illness trajectory. The major goals of this cluster randomized trial (CRT) are to (1) evaluate the comparative effectiveness of usual care and JUMPSTART- ANAI, a culturally tailored ACP communication intervention, for prompting patient-driven ACP conversations between ANAI adults and primary care providers and to (1) identify key factors to successfully implement the intervention in health systems serving ANAI adults with serious illness.
Read the detailed description
Despite a disproportionate burden of serious illness, Alaska Native and American Indian (ANAI) people are far less likely than their peers in the general US population to use palliative care, including advance care planning (ACP), which aims to align medical care with patients' values, goals, and preferences. ACP has been demonstrated to result in decreased depression, anxiety, and grief for patients and their families, increased symptom management, and fewer non-beneficial and unwanted end-of-life treatments. ACP is typically documented in advance directives (ADs) that specify patient preferences for life-sustaining treatments and who can make medical decisions on their behalf. Yet, ANAI people ages 55 and older are half as likely to have ADs as their White peers. A previous study culturally tailored and piloted an ACP communication intervention-JUMPSTART-ANAI-among 68 ANAI adults with serious illness in a Tribal health system in Alaska. This project builds on the previous study with a type 1 hybrid effectiveness-implementation trial of JUMPSTART-ANAI. The goal of this study is tailor an implementation plan for JUMPSTART-ANAI, evaluate the comparative effectiveness of the intervention and usual care for promoting patient-driven ACP communication, as measured by ADs documented in the electronic health record and identify key factors for successfully implementing JUMPSTART-ANAI in primary care systems serving ANAI adults with serious illness. Increasing access to culturally appropriate, evidence-based ACP is a high priority for Alaska Native health leaders and communities. By evaluating the effectiveness of a culturally tailored ACP intervention and tailoring implementation of the intervention for use in routine primary care, this study will generate critical information for implementing and improving palliative care services among a rapidly growing population of ANAI adults with serious illness.
- Conditions
- Advance Care Planning
- Being tested
- JUMPSTART-ANAI
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
JUMPSTART-ANAIBehavioural
Patient questionnaire about experiences, preferences, and concerns regarding ACP followed by feedback form with "tips" for initiating ACP conversation with provider at next clinical visit.
| Study group | Role | What they receive |
|---|---|---|
| Jumpstart 1 | Experimental | Questionnaire on advance care planning experiences, preferences, and concerns Receives: Behavioral: JUMPSTART-ANAI |
| Jumpstart 2 | Active comparator | Questionnaire on advance care planning experiences, preferences, and concerns plus feedback form (patient and provider) Receives: Behavioral: JUMPSTART-ANAI |
| Usual care | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants with an advance directive in the electronic health record
New advance directive scanned into EHR
Measured: Baseline, 3 months, 6 months, 12 months
Secondary outcomes (2)
Quality of communication
Patient-rated quality of patient-provider communication
Measured: Baseline, 3 months
Psychological distress
Symptoms of anxiety and depression
Measured: Baseline, 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Aug 2024
- Study start1 Apr 2025
- Primary completion30 Dec 2026 (estimated)
- Study completion30 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Advance Care PlanningStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Southcentral Foundation
- Sponsor type
- University, hospital or other
- Collaborators
- University of Arkansas, University of Washington, University of Colorado, Denver, Alaska Native Tribal Health Consortium, University of Alaska Fairbanks, National Institute of Nursing Research (NINR)
- Responsible party
- Principal investigator, Jennifer Shaw, University of Alaska Fairbanks
- Investigators
- Jennifer Shaw, PhD, Principal investigator, University of Alaska Fairbanks
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06538493
- Sponsor's protocol ID
- 5R01NR020491
- Other IDs
- 5R01NR020491
- Acronym
- JUMP
- Status last verified
- Jun 2026
- First submitted
- 1 Aug 2024
- Last updated
- 9 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: IPD will not be shared. All data owned by Tribal authority.
Publications
Lillie KM, Dirks LG, Curtis JR, Candrian C, Kutner JS, Shaw JL. Culturally Adapting an Advance Care Planning Communication Intervention With American Indian and Alaska Native People in Primary Care. J Transcult Nurs. 2020 Mar;31(2):178-187. doi: 10.1177/1043659619859055. Epub 2019 Jul 1.
PubMed 31258037Shaw J, Medlock S, Singh RS, Piromalli C, Trainor JK, Johnson R, Rollolazo S, Fieldhouse C, Mortenson R, Landes SJ. Evaluating a tailored communication tool to increase advance care planning among Alaska Native and American Indian people in primary care: A type 1 hybrid effectiveness-implementation cluster randomized trial protocol. Contemp Clin Trials. 2026 Jun;165:108305. doi: 10.1016/j.cct.2026.108305. Epub 2026 Apr 12.
PubMed 41974413Singh RS, Landes SJ, Medlock S, Piromalli C, Mortenson R, Shaw J. Collaborative Implementation Planning to Jumpstart Advance Care Planning with Alaska Native and American Indian peoples in Primary Care. Res Sq [Preprint]. 2025 Sep 19:rs.3.rs-7400899. doi: 10.21203/rs.3.rs-7400899/v1.
PubMed 41001527
Study at a glance
From the registry record, last updated by the sponsor on 9 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Jumpstarting Advance Care Planning With ANAI People in Primary Care
- ClinicalTrials.gov ID
- NCT06538493
- Acronym / sponsor ID
- JUMP / 5R01NR020491
- Conditions
- Advance Care Planning
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- Southcentral FoundationUniversity, hospital or other
- Collaborators
- University of Arkansas, University of Washington, University of Colorado, Denver, Alaska Native Tribal Health Consortium, University of Alaska Fairbanks, National Institute of Nursing Research (NINR)
- Study start
- 1 Apr 2025 (actual)
- Primary completion
- 30 Dec 2026 (estimated)
- Study completion
- 30 May 2027 (estimated)
- First posted
- 5 Aug 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The older Alaska Native/American Indian (ANAI) population is increasing at twice the rate of the general population with a higher burden of serious illness. Older ANAI adults with serious illness are half as likely to have advance directives (AD), indicating a need for improved access to and utilization of advance care planning (ACP) to ensure that medical care aligns with the values, goals, and preferences of ANAI patients and their families throughout the illness trajectory. The major goals of this cluster randomized trial (CRT) are to (1) evaluate the comparative effectiveness of usual care and JUMPSTART- ANAI, a culturally tailored ACP communication intervention, for prompting patient-driven ACP conversations between ANAI adults and primary care providers and to (1) identify key factors to successfully implement the intervention in health systems serving ANAI adults with serious illness.
Detailed description
Despite a disproportionate burden of serious illness, Alaska Native and American Indian (ANAI) people are far less likely than their peers in the general US population to use palliative care, including advance care planning (ACP), which aims to align medical care with patients' values, goals, and preferences. ACP has been demonstrated to result in decreased depression, anxiety, and grief for patients and their families, increased symptom management, and fewer non-beneficial and unwanted end-of-life treatments. ACP is typically documented in advance directives (ADs) that specify patient preferences for life-sustaining treatments and who can make medical decisions on their behalf. Yet, ANAI people ages 55 and older are half as likely to have ADs as their White peers. A previous study culturally tailored and piloted an ACP communication intervention-JUMPSTART-ANAI-among 68 ANAI adults with serious illness in a Tribal health system in Alaska. This project builds on the previous study with a type 1 hybrid effectiveness-implementation trial of JUMPSTART-ANAI. The goal of this study is tailor an implementation plan for JUMPSTART-ANAI, evaluate the comparative effectiveness of the intervention and usual care for promoting patient-driven ACP communication, as measured by ADs documented in the electronic health record and identify key factors for successfully implementing JUMPSTART-ANAI in primary care systems serving ANAI adults with serious illness. Increasing access to culturally appropriate, evidence-based ACP is a high priority for Alaska Native health leaders and communities. By evaluating the effectiveness of a culturally tailored ACP intervention and tailoring implementation of the intervention for use in routine primary care, this study will generate critical information for implementing and improving palliative care services among a rapidly growing population of ANAI adults with serious illness.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Jumpstart 1 | Experimental | Behavioral: JUMPSTART-ANAIQuestionnaire on advance care planning experiences, preferences, and concerns |
| Jumpstart 2 | Active comparator | Behavioral: JUMPSTART-ANAIQuestionnaire on advance care planning experiences, preferences, and concerns plus feedback form (patient and provider) |
| Usual care | No intervention | – |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Age 40 or older with a qualifying serious illness condition (e.g., COPD) OR Age 65 or older (regardless of diagnosis) AND Alaska Native and/or American Indian AND Empaneled to a primary care provider AND 2 or more to primary care in last 12 months AND No advance directives documented in electronic health record
Key exclusion criteria (1 listed)
- Unable to provide informed consent AND/OR Not able to complete 30-minute study visit by phone, video call, or in person
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| JUMPSTART-ANAIPatient questionnaire about experiences, preferences, and concerns regarding ACP followed by feedback form with "tips" for initiating ACP conversation with provider at next clinical visit. | Behavioural | Jumpstart 1, Jumpstart 2 |
Primary outcome
Number of participants with an advance directive in the electronic health record
Time frame: Baseline, 3 months, 6 months, 12 months
New advance directive scanned into EHR
2 secondary outcomes
Quality of communication
Time frame: Baseline, 3 months
Psychological distress
Time frame: Baseline, 3 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jul 2026.
- Background: PubMed 31258037Lillie KM, Dirks LG, Curtis JR, Candrian C, Kutner JS, Shaw JL. Culturally Adapting an Advance Care Planning Communication Intervention With American Indian and Alaska Native People in Primary Care. J Transcult Nurs. 2020 Mar;31(2):178-187. doi: 10.1177/1043659619859055. Epub 2019 Jul 1.
- Background: PubMed 41974413Shaw J, Medlock S, Singh RS, Piromalli C, Trainor JK, Johnson R, Rollolazo S, Fieldhouse C, Mortenson R, Landes SJ. Evaluating a tailored communication tool to increase advance care planning among Alaska Native and American Indian people in primary care: A type 1 hybrid effectiveness-implementation cluster randomized trial protocol. Contemp Clin Trials. 2026 Jun;165:108305. doi: 10.1016/j.cct.2026.108305. Epub 2026 Apr 12.
- Background: PubMed 41001527Singh RS, Landes SJ, Medlock S, Piromalli C, Mortenson R, Shaw J. Collaborative Implementation Planning to Jumpstart Advance Care Planning with Alaska Native and American Indian peoples in Primary Care. Res Sq [Preprint]. 2025 Sep 19:rs.3.rs-7400899. doi: 10.21203/rs.3.rs-7400899/v1.
- Individual participant dataSharing planned: No. IPD will not be shared. All data owned by Tribal authority.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
John Trainor, PhD, MPH contact
Jennifer Shaw, PhD principal investigator
University of Alaska Fairbanks
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing JUMPSTART-ANAI in people with Advance Care Planning, run by Southcentral Foundation at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 9 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Shannon Medlock, MS ((907)729-6322, smedlock@scf.cc), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants with an advance directive in the electronic health record (time frame: Baseline, 3 months, 6 months, 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06538493, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jul 2026.