Coronary Artery DiseaseNCT06525233
Interval Aerobic Training and Continious Training
An observational study of Coronary Artery Disease and Exercise Addiction, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
Trial summary
This research is comparing the effects of interval and continuous training which are the two types of aerobic training on persons' life quality and exercise capacity on coronary artery disease patients. Read more about this study
- Who is it for?
- Ages 40 to 80 yearsHealthy volunteers can take part
- Conditions the study is for
- Coronary Artery Disease, Exercise Addiction
- What is being tested?
- Physiotherapy and rehabilitation
- How many people
- 40 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 5 May 2018to 20 May 2019
- How long will I take part?
- 6 Weeks
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 80 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Name-Surname, age, sex, body-weight index, educational status, married/single/divorced, job and clinical background (If has any surgery and myocardial infarction)
Who may be able to join
- diagnosed coronary artery disease
- aged between 40-80
- over %55 ejection fraction
Who cannot join
- mental and physical disability
- unstable angina pectoris
- thrombophlebitis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparision the Effect of Interval Aerobic Training and Continious Training on Coronary Artery Disease
This research is comparing the effects of interval and continuous training which are the two types of aerobic training on persons' life quality and exercise capacity on coronary artery disease patients.
Read the detailed description
The participants are diagnosed coronary artery disease aged between 40- 80 and have no mental and physical disability to take part in research. The participants' demographic infos and clinical story were recorded. To evaluate exercise capacity we used the symptom-limited exercise test (ETT) and six minute walking test (6DYT). We evaluate the life quality by using Short Form-36 (SF-36).
All those evaluation tests are done before and after training. Participants are randomly divided into two groups, the first group took part in interval aerobic training (AAE) while the other group was joining in continuous training (SAE) three times a week during 6 weeks. In both groups, significant changes were found in ETT, test time and 6 DYT scores after the rehabilitation program (p<0,05). But only AAE group have important statistical values comparing to SAE group on test time and 6DYT scores. After training SAE group showed significant statistical change in every SF-36 parameter, while AAE group showing significant values except energy/fatigue. AAE group have statistically significant changes comparing to SAE group on that parameters; physical function, role limitations due to physical function, role limitations due to emotional function and general health (p<0,05). Consequently AAE is much more tolerable comparing to SAE and AAE is considered more effective in increasing some parameters. On the other hand, we observed that both training types can be used in cardiac rehabilitation safely.
- Conditions
- Coronary Artery Disease, Exercise Addiction
- Being tested
- Physiotherapy and rehabilitation
- Keywords
- continious training, interval training
- Medical subject headings
- Coronary Artery Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Physiotherapy and rehabilitationOther
The aerobic exercise is very crucial part of cardiac rehabilitation. This study compares the effects of interval and continuous training which are the two types of aerobic training on persons' life quality and exercise capacity diagnosed coronary artery disease patients.
| Study group | Role | What they receive |
|---|---|---|
| Treatment | humans that diagnosed as coronary artery disease, joined two aerobic exercise groups. One of this group includes interval exercise and the other one includes continuous exercise. Receives: Other: Physiotherapy and rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
the effect of intermittent and continuous aerobic exercise on exercise capacity
we used the symptom-limited exercise test and six minute walking test (6DYT). All evaluation tests are done before and after training. Participants were into randomised two groups: interval aerobic training (AAE) and continuous aerobic training (SAE). Training lasted three times a week during 6 weeks. In both groups, significant changes were found in evaluation tests scores after the rehabilitation program (p<0,05). But only AAE group have important statistical difference comparing to SAE group on test time and 6DYT scores.
Measured: 30 minutes 3 times a week during 6 weeks
Secondary outcomes (1)
the effect of intermittent and continuous aerobic exercise on life quality
The participants have no mental and physical disability to join in research. The participants' demographic infos and clinical story were recorded.We evaluate the life quality by using Short Form-36 (SF-36). All evaluation tests are done before and after training. Participants were into randomised two groups: interval aerobic training (AAE) and continuous aerobic training (SAE).After training SAE group showed significant statistical change in every SF-36 parameter, while AAE group showing significant values except energy/fatigue. AAE group have statistically significant changes comparing to SAE group on that parameters; physical function, role limitations due to physical function, role limitations due to emotional function and general health (p<0,05). Consequently AAE is much more tolerable comparing to SAE and AAE is considered more effective in increasing some parameters. On the other hand, we observed that both training types can be used in cardiac rehabilitation safely.
Measured: 30 minutes 3 times a week during 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jul 2024
- Study start5 May 2018
- Primary completion2 Apr 2019
- Study completion20 May 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Coronary Artery DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case crossover
- Time perspective
- Prospective
- Enrolment
- 40 participants (actual)
- Target duration
- 6 Weeks
Sponsor and investigators
- Lead sponsor
- Istanbul Medipol University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, gulay karacaoglu, Istanbul Medipol University Hospital
- Investigators
- Fatma Mutluay, Study director, medipol univercity
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06525233
- Sponsor's protocol ID
- aerobicexercise
- Status last verified
- Jul 2024
- First submitted
- 17 Aug 2019
- Last updated
- 29 Jul 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Cardiac rehabilitation is very popular at nowadays and which type exercise good on cardiac rehabilitation is not known exactly
Publications
Yalcin G, Mutluay F. The effect of interval and continuous aerobic training on exercise capacity and health-related quality of life in people with coronary artery DISEASE: A randomized controlled trial. Respir Med. 2026 Feb;252:108634. doi: 10.1016/j.rmed.2026.108634. Epub 2026 Jan 4.
PubMed 41494581
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparision the Effect of Interval Aerobic Training and Continious Training on Coronary Artery Disease
- ClinicalTrials.gov ID
- NCT06525233
- Acronym / sponsor ID
- aerobicexercise
- Conditions
- Coronary Artery Disease, Exercise Addiction
- Keywords
- continious training, interval training
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Istanbul Medipol University HospitalUniversity, hospital or other
- Study start
- 5 May 2018 (actual)
- Primary completion
- 2 Apr 2019 (actual)
- Study completion
- 20 May 2019 (actual)
- First posted
- 29 Jul 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This research is comparing the effects of interval and continuous training which are the two types of aerobic training on persons' life quality and exercise capacity on coronary artery disease patients.
Detailed description
The participants are diagnosed coronary artery disease aged between 40- 80 and have no mental and physical disability to take part in research. The participants' demographic infos and clinical story were recorded. To evaluate exercise capacity we used the symptom-limited exercise test (ETT) and six minute walking test (6DYT). We evaluate the life quality by using Short Form-36 (SF-36).
All those evaluation tests are done before and after training. Participants are randomly divided into two groups, the first group took part in interval aerobic training (AAE) while the other group was joining in continuous training (SAE) three times a week during 6 weeks. In both groups, significant changes were found in ETT, test time and 6 DYT scores after the rehabilitation program (p<0,05). But only AAE group have important statistical values comparing to SAE group on test time and 6DYT scores. After training SAE group showed significant statistical change in every SF-36 parameter, while AAE group showing significant values except energy/fatigue. AAE group have statistically significant changes comparing to SAE group on that parameters; physical function, role limitations due to physical function, role limitations due to emotional function and general health (p<0,05). Consequently AAE is much more tolerable comparing to SAE and AAE is considered more effective in increasing some parameters. On the other hand, we observed that both training types can be used in cardiac rehabilitation safely.
Study design
- Observational model
- Case crossover
- Time perspective
- Prospective
- Target follow-up
- 6 Weeks
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Treatment | – | Other: Physiotherapy and rehabilitationhumans that diagnosed as coronary artery disease, joined two aerobic exercise groups. One of this group includes interval exercise and the other one includes continuous exercise. |
Who may qualify
- Ages
- 40 to 80 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Name-Surname, age, sex, body-weight index, educational status, married/single/divorced, job and clinical background (If has any surgery and myocardial infarction)
Key inclusion criteria (3 listed)
- diagnosed coronary artery disease
- aged between 40-80
- over %55 ejection fraction
Key exclusion criteria (3 listed)
- mental and physical disability
- unstable angina pectoris
- thrombophlebitis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Physiotherapy and rehabilitationThe aerobic exercise is very crucial part of cardiac rehabilitation. This study compares the effects of interval and continuous training which are the two types of aerobic training on persons' life quality and exercise capacity diagnosed coronary artery disease patients. | Other | Treatment |
Primary outcome
the effect of intermittent and continuous aerobic exercise on exercise capacity
Time frame: 30 minutes 3 times a week during 6 weeks
we used the symptom-limited exercise test and six minute walking test (6DYT). All evaluation tests are done before and after training. Participants were into randomised two groups: interval aerobic training (AAE) and continuous aerobic training (SAE). Training lasted three times a week during 6 weeks. In both groups, significant changes were found in evaluation tests scores after the rehabilitation program (p<0,05). But only AAE group have important statistical difference comparing to SAE group on test time and 6DYT scores.
1 secondary outcome
the effect of intermittent and continuous aerobic exercise on life quality
Time frame: 30 minutes 3 times a week during 6 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2024.
- Derived from this study: PubMed 41494581Yalcin G, Mutluay F. The effect of interval and continuous aerobic training on exercise capacity and health-related quality of life in people with coronary artery DISEASE: A randomized controlled trial. Respir Med. 2026 Feb;252:108634. doi: 10.1016/j.rmed.2026.108634. Epub 2026 Jan 4.
- Individual participant dataSharing planned: Yes. Cardiac rehabilitation is very popular at nowadays and which type exercise good on cardiac rehabilitation is not known exactly
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Fatma Mutluay study director
medipol univercity
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Coronary Artery Disease and Exercise Addiction, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
the effect of intermittent and continuous aerobic exercise on exercise capacity (time frame: 30 minutes 3 times a week during 6 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06525233, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2024.