Post Procedural ErythemaNCT06477172
Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures
An observational study of Post Procedural Erythema, run by Acorn Biolabs Inc. at 42 sites in 2 countries.
Trial summary
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Post Procedural Erythema
- How many people
- 500 participants
- Where
- 42 sitesin 2 countries
- Study dates
- 9 Sep 2024to Feb 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The study population will be patients planning a medical aesthetic procedure and use of Autologous Hair Follicle Secretome cosmetic post-procedure.
Who may be able to join
- Male and Female
- Ages: 18-60
- Any Fitzpatrick skin type
- Planning a medical aesthetic procedure
- For subjects receiving hair procedures (closed to enrollment):
- Androgenic alopecia
Show all 16Show fewer
- Traction alopecia
- Scarring alopecia
- Stable use of any medication or supplement for hair loss, including finasteride, any other 5 α-reductase inhibitor, minoxidil, steroids, or hormonal products, during the 3 months prior to enrollment in the study is allowed.
- No intention to start new hair growth medications or change dose of hair growth medications from the time of consent through the end of the study follow-up period.
- Undergoing one of the following medical aesthetic procedures:
- Laser resurfacing of the face (ablative or non-ablative) or Ellacor of the face (Ellacor closed to enrollment)
- Tixel of the face
- Keralase of the scalp (scalp treatment closed to enrollment)
- Acne Scars and Surgery scars, either old or new as long as old scars are also being treated with ablative or non-ablative laser or microneedling (e.g. abdominoplasty, breast reduction/ reconstruction/enhancement, post-weight loss, etc.
- Planning to use Acorn Autologous Hair Follicle Secretome cosmetic product
Who cannot join
- Pregnant or Breastfeeding
- Participation in an interventional clinical trial in the last 30 days
- Use of other topical cosmetic products that may confound results
- Use of retinoids within 7 days prior to facial procedure
- For those receiving hair treatment, must not have had a hair transplant in the treatment area within the past 12 months
- Any health condition that in the investigator's opinion should preclude participation in study
Trial locations and contacts
42 sites in 2 countries. Contact the study team or a site near you to ask about taking part.
42 sites in 2 countries
United States33 sites, 18 recruiting
- Completed
Austin Plastic Surgeon
Austin, Texas, 78758
- Withdrawn
Arash Moradzadeh MD
Beverly Hills, California, 90210
- Withdrawn
Glenn Vallecillos, MD Inc
Beverly Hills, California, 90210
- Withdrawn
Skin Wellness Dermatology
Birmingham, Alabama, 35209
- Withdrawn
ICON Antiaging & Aesthetics
Birmingham, Michigan, 48009
- Recruiting
Bauman Medical
Boca Raton, Florida, 33432
Liz Ashe, 561-394-0024, lashe@baumanmedical.com
Alan J. Bauman, MD
- Recruiting
Boulder Longevity Institute
Boulder, Colorado, 80303
Kristen Robb, (303) 579-3101, krobb@boulderlongevity.com
Tracey Bastic, (303) 579-3101, tbastic@boulderlongevity.com
- Completed
Davis Cosmetic Plastic Surgery
Cherry Hill, New Jersey, 08003
- Completed
Hive Aesthetic LLC
Chicago, Illinois, 60657
- Recruiting
Dallas Plastic Surgery Institute
Dallas, Texas, 75225
Rachelle Winkle, (214) 821-9114, rachelle.winkle@dpsi.org
Brianna Escamilla, (214) 821-9114, brianna.escamilla@dpsi.org
- Recruiting
Behr Laser & Skin Care Center
Fresno, California, 93720
Cierra Esparza, (559) 435-7546, cierrae@435skin.com
Ashley Garcia, (559) 435-7546, garciaashley43@mygya.com
- Recruiting
Aesthetics By Dr. Lee
Granite Bay, California, 95746
Luis Lee, MD, (916)888-8988, admin@drluislee.com
Luis Lee, MD
- Recruiting
Chernoff Cosmetic Surgery
Indianapolis, Indiana, 46220
Jenna Himelstein, 317-5738899, jenna@drchernoff.com
Gregory Chernoff, MD
- Completed
BEAUTY by BUFORD
Lone Tree, Colorado, 80124
- Recruiting
Carlo Honrado, MD, FACS
Los Angeles, California, 90067
Madison Webb, 310-286-0043, madison@drhonrado.com
Carlo Honrado, MD, FACS
- Recruiting
AIEREM Aesthetics Spa & Plastic Surgery
Manhattan, New York, 75231
Jessica Hill, 516-614-1880, exec_admin@airem.com
Eunice Park, MD
- Withdrawn
Marcus Medical
Manhattan Beach, California, 90266
- Recruiting
N2 Aesthetics
Manhattan Beach, California, 90266
Lauren Matoska, 310-510-6262, Lauren@n2aesthetics.com
Chloe Lehman, 310 510 6262, Chloe@n2aesthetics.com
- Recruiting
Marina Plastic Surgery
Marina del Rey, California, 90292
Justin Perez, MD
- Recruiting
Lewis Dermatology and Associates
New York, New York, 10021
Amy Lewis, MD
- Recruiting
Unger Medical Hair Transplant Clinic
New York, New York, 10021
Zinaria Williams, MD, 212-2494369, drzinaria@ungermedical.com
Robin Unger, MD
- Completed
SkinLabRx
New York, New York, 10028
- Not yet recruiting
Sadick Dermatology
New York, New York, 10075
Suliema Arruda, MD, (212) 772-7242, sarruda@sadickdermatology.com
Neil Sadick, MD
- Completed
M Beauty by Tess
San Diego, California, 92126
- Completed
BelleSante
Scottsdale, Arizona, 85260
- Withdrawn
Mirror Plastic Surgery
St. Petersburg, Florida, 33701
- Recruiting
AIEREM Aesthetics Spa & Plastic Surgery
Syosset, New York, 11791
Jessica Hill, 516-614-1880, exec_admin@airem.com
Eunice Park, MD
- Recruiting
Aesthetic House
The Woodlands, Texas, 77380
Jill Campbell, FNP-C, (281) 642-2501
Anna Tarasiewicz, (281) 642-2501, atarasiewicz@bookaesthetichouse.com
- Recruiting
US Dermatology Partners / Dermatology Associates of Tyler
Tyler, Texas, 75703
Jennifer D Holman, MD
- Recruiting
AG Aesthetic Centre
Vancouver, Washington, 98660
Melissa Mohr, (360) 869-4200, melissa@allengabrielmd.com
Allen Gabriel, MD
- Withdrawn
Modern Aesthetics
Walnut Creek, California, 94598
- Completed
Dr. Christie
West Hollywood, California, 90069
- Recruiting
Ziering Medical
West Hollywood, California, 90069
Paola Morales, paola@zieringhair.com, paola@zieringhair.com
Craig L. Ziering, DO FAOCD FISHRS
Canada9 sites, 1 recruiting
- Completed
Dr. Amber Bocknek
Aurora, Ontario, L4G1B9
- Completed
Sanjeev Goel MD Peak Human
Brampton, Ontario, L6W 3E1
- Completed
Clinique Antiaging
Montreal, Quebec, H3A 1S2
- Completed
Compass Dermatology
Toronto, Ontario, M4S 2N5
- Completed
Rejuuv
Toronto, Ontario, M5R 0C7
- Recruiting
Dr. Nowell Solish Cosmetic Dermatologist
Toronto, Ontario, M5R 3N8
Dawne Bursey, 416-964-8888, dawne@solish.com
Nowell Solish, MD
- Withdrawn
FCP Dermatology
Toronto, Ontario, M5X 1A9
- Completed
BeSpoke Wellness
Toronto, Ontario
- Completed
Dr. Jean Carruthers Cosmedic
Vancouver, British Columbia, V5Z 4E1
About this study
Official title: A Multi-site, Prospective, Observational Study of Autologous Hair Follicle Secretome (aHFS) as an Adjunct to Medical Aesthetic Procedures
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Read the detailed description
This non-interventional, observation study is to collect real-world data on the use of an autologous, hair follicle derived secretome topical cosmetic product following various medical aesthetic procedures.
- Conditions
- Post Procedural Erythema
What is being measured
The primary outcome is the main question the study is designed to answer.
Post-Procedure Symptoms
Symptoms of redness, swelling, oozing, pain, tenderness, crusting, itching and discoloration will be measured using a 1-10 likert scale with 0 being best possible and 10 being worst imaginable.
Measured: 1-7 days
Downtime Questionnaire
Questionnaire asking what activities would they have done, if it were not for their face appearance. Date of end of downtime captured.
Measured: 1-7 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jun 2024
- Study start9 Sep 2024
- Primary completionFeb 2027 (estimated)
- Study completionFeb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Post Procedural ErythemaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Acorn Biolabs Inc.
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
- Investigators
- Drew Taylor, PhD, Study chair, Acorn Biolabs
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06477172
- Sponsor's protocol ID
- ACN-101
- Status last verified
- Mar 2026
- First submitted
- 21 Jun 2024
- Last updated
- 26 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Multi-site, Prospective, Observational Study of Autologous Hair Follicle Secretome (aHFS) as an Adjunct to Medical Aesthetic Procedures
- ClinicalTrials.gov ID
- NCT06477172
- Acronym / sponsor ID
- ACN-101
- Conditions
- Post Procedural Erythema
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 500 participants (estimated)
- Lead sponsor
- Acorn Biolabs Inc.Industry (pharma, biotech, devices)
- Study start
- 9 Sep 2024 (actual)
- Primary completion
- Feb 2027 (estimated)
- Study completion
- Feb 2027 (estimated)
- First posted
- 27 Jun 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.
Detailed description
This non-interventional, observation study is to collect real-world data on the use of an autologous, hair follicle derived secretome topical cosmetic product following various medical aesthetic procedures.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The study population will be patients planning a medical aesthetic procedure and use of Autologous Hair Follicle Secretome cosmetic post-procedure.
Key inclusion criteria (16 listed)
- Male and Female
- Ages: 18-60
- Any Fitzpatrick skin type
- Planning a medical aesthetic procedure
- For subjects receiving hair procedures (closed to enrollment):
Key exclusion criteria (6 listed)
- Pregnant or Breastfeeding
- Participation in an interventional clinical trial in the last 30 days
- Use of other topical cosmetic products that may confound results
- Use of retinoids within 7 days prior to facial procedure
- For those receiving hair treatment, must not have had a hair transplant in the treatment area within the past 12 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Post-Procedure Symptoms
Time frame: 1-7 days
Symptoms of redness, swelling, oozing, pain, tenderness, crusting, itching and discoloration will be measured using a 1-10 likert scale with 0 being best possible and 10 being worst imaginable.
Downtime Questionnaire
Time frame: 1-7 days
Questionnaire asking what activities would they have done, if it were not for their face appearance. Date of end of downtime captured.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Oct 2026.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Drew Taylor, PhD study chair
Acorn Biolabs
42 sites in 2 countries: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Post Procedural Erythema, run by Acorn Biolabs Inc. at 42 sites in 2 countries.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 16 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 42 sites in United States, Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Lisa Campbell, PhD (858-997-7447, lisa.campbell@acorn.me), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Post-Procedure Symptoms (time frame: 1-7 days). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Oct 2026.