Alcohol ToxicityAIACNCT06397716
Public Health Initiative on Alcohol Flushing
A study testing ALDH2 Genotyping in people with Alcohol Toxicity, run by Stanford University at 1 site in United States.
Trial summary
The overall aim of the study is to raise awareness of alcohol flushing and its health risks to the general population. The primary objective is to see if spreading awareness of the health risks of alcohol flushing and understanding personalized genotype information will lead to changes in alcohol consumption behavior. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Alcohol Toxicity
- What is being tested?
- ALDH2 Genotyping
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 70 participants
- Where
- 1 siteUnited States
- Study dates
- 25 Apr 2024to 25 Apr 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult age over 18
- Native English speaker
Who cannot join
- None
Trial locations and contacts
1 site in 1 country.
About this study
Official title: A Public Health Education and Awareness Initiative on Alcohol Flushing and Alcohol-related Cancer in Asian Communities
The overall aim of the study is to raise awareness of alcohol flushing and its health risks to the general population.
The primary objective is to see if spreading awareness of the health risks of alcohol flushing and understanding personalized genotype information will lead to changes in alcohol consumption behavior.
- Conditions
- Alcohol Toxicity
- Being tested
- ALDH2 Genotyping
- Keywords
- Alcohol Flushing
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ALDH2 GenotypingGenetic
Cheek swab for PCR testing of ALDH2 genotype.
| Study group | Role | What they receive |
|---|---|---|
| Genotype Revealed | Experimental | Subjects with ALDH2 mutation will be notified of positive genotype results after testing completed. Receives: Genetic: ALDH2 Genotyping |
| Gentoype Not-Revealed | Placebo comparator | Subjects with ALDH2 mutation will not be notified of positive genotype results until after study completed. Receives: Genetic: ALDH2 Genotyping |
What is being measured
The primary outcome is the main question the study is designed to answer.
Alcohol Flushing Awareness
Alcohol flushing reaction awareness questionnaire, scale from 0 to 4, higher score is better outcome
Measured: Baseline, 1 month, 3 month
Alcohol Consumption Habits 1
Number of days alcohol was consumed in past 30 days
Measured: Baseline, 1 month, 3 month
Alcohol Consumption Habits 2
Number of days 2 or more drinks of alcohol was consumed in past 30 days
Measured: Baseline, 1 month, 3 month
Alcohol Consumption Habits 3
Average number of alcohol consumed on days alcohol was consumed
Measured: Baseline, 1 month, 3 month
Alcohol Consumption Habits 4
Largest number of drinks of alcohol consumed in one sitting
Measured: Baseline, 1 month, 3 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 May 2024
- Study start25 Apr 2024
- Primary completion25 Apr 2024
- Study completion25 Apr 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Alcohol ToxicityStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 70 participants (actual)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- Stanford Center for Asian Health Research and Education
- Responsible party
- Principal investigator, Kevin Chang, Stanford University
- Investigators
- Kevin Chang, MD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06397716
- Sponsor's protocol ID
- 71764
- Acronym
- AIAC
- Status last verified
- Apr 2026
- First submitted
- 29 Apr 2024
- Last updated
- 23 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Public Health Education and Awareness Initiative on Alcohol Flushing and Alcohol-related Cancer in Asian Communities
- ClinicalTrials.gov ID
- NCT06397716
- Acronym / sponsor ID
- AIAC / 71764
- Conditions
- Alcohol Toxicity
- Keywords
- Alcohol Flushing
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 70 participants (actual)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- Stanford Center for Asian Health Research and Education
- Study start
- 25 Apr 2024 (actual)
- Primary completion
- 25 Apr 2024 (actual)
- Study completion
- 25 Apr 2024 (actual)
- First posted
- 3 May 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The overall aim of the study is to raise awareness of alcohol flushing and its health risks to the general population.
The primary objective is to see if spreading awareness of the health risks of alcohol flushing and understanding personalized genotype information will lead to changes in alcohol consumption behavior.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Genotype Revealed | Experimental | Genetic: ALDH2 GenotypingSubjects with ALDH2 mutation will be notified of positive genotype results after testing completed. |
| Gentoype Not-Revealed | Placebo comparator | Genetic: ALDH2 GenotypingSubjects with ALDH2 mutation will not be notified of positive genotype results until after study completed. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Adult age over 18
- Native English speaker
Key exclusion criteria (1 listed)
- None
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ALDH2 GenotypingCheek swab for PCR testing of ALDH2 genotype. | Genetic | Genotype Revealed, Gentoype Not-Revealed |
Primary outcome
Alcohol Flushing Awareness
Time frame: Baseline, 1 month, 3 month
Alcohol flushing reaction awareness questionnaire, scale from 0 to 4, higher score is better outcome
Alcohol Consumption Habits 1
Time frame: Baseline, 1 month, 3 month
Number of days alcohol was consumed in past 30 days
Alcohol Consumption Habits 2
Time frame: Baseline, 1 month, 3 month
Number of days 2 or more drinks of alcohol was consumed in past 30 days
Alcohol Consumption Habits 3
Time frame: Baseline, 1 month, 3 month
Average number of alcohol consumed on days alcohol was consumed
Alcohol Consumption Habits 4
Time frame: Baseline, 1 month, 3 month
Largest number of drinks of alcohol consumed in one sitting
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kevin Chang, MD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ALDH2 Genotyping in people with Alcohol Toxicity, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Alcohol Flushing Awareness (time frame: Baseline, 1 month, 3 month). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Apr 2026.