Musculoskeletal ManipulationsRACHIMOBNCT06374862
Effects of Specific Thoracic Spine Mobilizations on Muscle Activity in a Healthy Volunteer Population
A study testing mobilization and no effect in people with Musculoskeletal Manipulations and Range of Motion, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
In this study, the investigators will examine the effect of manual therapy on the thoracic spine and its impact on the muscular strength gain of the thoracic extensors. Treatment with manual therapy, as described by Maitland, consists of a specific mobilization of the thoracic spine in the postero-anterior direction… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Musculoskeletal Manipulations, Range of Motion, Muscle Strength
- What is being tested?
- mobilization and no effect
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 156 participants
- Where
- 1 siteFrance
- Study dates
- 28 Mar 2024to 16 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Ages 18 to 65,
- healthy volunteer,
- membership in a social security scheme
Who cannot join
- Severe spinal trauma within the last 6 months
- history of low back pain, back pain, and/or neck pain within the last 6 months,
- history of spinal surgery,
- history of chronic systemic disease (cardiac, respiratory, diabetes, etc.),
- volunteer with Pacemaker, history of rheumatological pathology (rheumatoid arthritis, ankylosing spondylitis, Scheuermann's disease, etc.),
- patient under guardianship,curatorship, safeguard of justice, patient deprived of liberty, pregnant woman and patient without Red Flags Social Security described in literature.
Trial locations and contacts
1 site in 1 country.
About this study
In this study, the investigators will examine the effect of manual therapy on the thoracic spine and its impact on the muscular strength gain of the thoracic extensors. Treatment with manual therapy, as described by Maitland, consists of a specific mobilization of the thoracic spine in the postero-anterior direction on the transverse and spiny processes of the thoracic vertebrae. To ensure the relevance of the measures, and to better control the occurrence of biases inherent to the practice of manual therapy, the investigators constituted three distinct groups: an intervention group, a control group and a group without intervention. In short, this methodology will allow us to explore in detail the effects of specific spinal mobilization on motor control, while taking into account placebo response elements and natural variations in the results
- Conditions
- Musculoskeletal Manipulations, Range of Motion, Muscle Strength, Peripheral Joints in Upper Quarters
- Being tested
- mobilization, no effect
- Keywords
- Musculoskeletal Manipulations, Range of Motion, Muscle Strength, peripheral joints in upper quarters
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
mobilizationOther
specific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine
no effectOther
a mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect.
| Study group | Role | What they receive |
|---|---|---|
| Interventional | Experimental | This study is of an interventional nature, because the investigators want to objectively assess the impact of specific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine. Receives: Other: mobilization |
| control | Sham comparator | This approach will help to determine whether there is spontaneous modulation of neuromuscular activity in the absence of intervention. Thus, the investigators can distinguish the effects of intervention from natural variations in the healthy subject. Receives: Other: no effect |
| no interventional | No intervention | A control group was also integrated to assess whether a mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect. This approach will allow to disentangle the real effects of mobilization from those that could result from psychomotor responses |
What is being measured
The primary outcome is the main question the study is designed to answer.
electrical activity assessment of the spine extensor muscles using EMG
Measured: 1 hour
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Apr 2024
- Study start28 Mar 2024
- Primary completion28 Oct 2025
- Study completion16 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Musculoskeletal ManipulationsStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 156 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06374862
- Sponsor's protocol ID
- PI2024_843_0008
- Acronym
- RACHIMOB
- Status last verified
- May 2025
- First submitted
- 16 Apr 2024
- Last updated
- 31 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Specific Thoracic Spine Mobilizations on Muscle Activity in a Healthy Volunteer Population
- ClinicalTrials.gov ID
- NCT06374862
- Acronym / sponsor ID
- RACHIMOB / PI2024_843_0008
- Conditions
- Musculoskeletal Manipulations, Range of Motion, Muscle Strength, Peripheral Joints in Upper Quarters
- Keywords
- Musculoskeletal Manipulations, Range of Motion, Muscle Strength, peripheral joints in upper quarters
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 156 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 28 Mar 2024 (actual)
- Primary completion
- 28 Oct 2025 (actual)
- Study completion
- 16 Feb 2026 (actual)
- First posted
- 19 Apr 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this study, the investigators will examine the effect of manual therapy on the thoracic spine and its impact on the muscular strength gain of the thoracic extensors. Treatment with manual therapy, as described by Maitland, consists of a specific mobilization of the thoracic spine in the postero-anterior direction on the transverse and spiny processes of the thoracic vertebrae. To ensure the relevance of the measures, and to better control the occurrence of biases inherent to the practice of manual therapy, the investigators constituted three distinct groups: an intervention group, a control group and a group without intervention. In short, this methodology will allow us to explore in detail the effects of specific spinal mobilization on motor control, while taking into account placebo response elements and natural variations in the results
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Interventional | Experimental | Other: mobilizationThis study is of an interventional nature, because the investigators want to objectively assess the impact of specific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine. |
| control | Sham comparator | Other: no effectThis approach will help to determine whether there is spontaneous modulation of neuromuscular activity in the absence of intervention. Thus, the investigators can distinguish the effects of intervention from natural variations in the healthy subject. |
| no interventional | No intervention | –A control group was also integrated to assess whether a mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect. This approach will allow to disentangle the real effects of mobilization from those that could result from psychomotor responses |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Ages 18 to 65,
- healthy volunteer,
- membership in a social security scheme
Key exclusion criteria (6 listed)
- Severe spinal trauma within the last 6 months
- history of low back pain, back pain, and/or neck pain within the last 6 months,
- history of spinal surgery,
- history of chronic systemic disease (cardiac, respiratory, diabetes, etc.),
- volunteer with Pacemaker, history of rheumatological pathology (rheumatoid arthritis, ankylosing spondylitis, Scheuermann's disease, etc.),
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| mobilizationspecific mobilization on neuromuscular functioning, thanks to surface EMG, before and after a specific mobilization of the spine | Other | Interventional |
| no effecta mobilization identified as "no effect" could modulate neuromuscular activity by a placebo effect. | Other | control |
Primary outcome
electrical activity assessment of the spine extensor muscles using EMG
Time frame: 1 hour
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing mobilization and no effect in people with Musculoskeletal Manipulations and Range of Motion, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
electrical activity assessment of the spine extensor muscles using EMG (time frame: 1 hour). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Mar 2026.