HIV SeropositivityMOST:PrEPNCT06334341
A Multilevel, Multiphase Optimization Strategy for PrEP (MOST:PrEP)
A study testing Computer-based simulation training for providers, Best Practice Alert and HIV Risk Assessment in people with HIV Seropositivity, run by Henry Ford Health System at 1 site in United States.
Trial summary
What is known: There are 1.2 million people in the US who meet the indications for PrEP; yet, disparities exist in uptake. For example, only 9% of Black and 16% of Latino individuals, compared to 65% of White individuals, have been prescribed PrEP. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- HIV Seropositivity
- What is being tested?
- Computer-based simulation training for providers, Best Practice Alert and HIV Risk Assessment
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 1,380 participants
- Where
- 1 siteUnited States
- Study dates
- 19 Jun 2024to 30 Jun 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Provider:≥ 18-years old
- Provider: employed at HFH as a primary care provider
- Provider: eligible to write prescriptions in the state of Michigan
- Patient: ≥ 18 years old
- Patient: have an appointment with a Henry Ford primary care clinic during the study period
- Patient: have an EHR account
- Patient: meet the indications for PrEP
Who cannot join
- Provider: not a HFH primary care provider
- Provider: does not have prescribing privileges in the state of Michigan
- Patient: currently prescribed or taking PrEP
- Patient: living with HIV
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Multilevel, Multiphase Optimization Strategy for PrEP: Patients and Providers in Primary Care
What is known: There are 1.2 million people in the US who meet the indications for PrEP; yet, disparities exist in uptake. For example, only 9% of Black and 16% of Latino individuals, compared to 65% of White individuals, have been prescribed PrEP. At Henry Ford Health (HFH) system, only 10% of eligible patients have been prescribed PrEP. Primary care is an ideal setting for PrEP to be offered as an HIV prevention method since providers see large numbers of patients who are HIV negative, with some who are at increased risk for HIV, and the primary care setting is often the point of entry to the healthcare system. The multiphase optimization strategy (MOST) framework is a novel, innovative way to identify an efficient intervention. What will be done: In this optimization trial, the investigators will test the effectiveness of intervention components, alone and in combination, on new PrEP prescriptions in primary care at HFH. First, feedback will be generated on context-specific (system and individual level) factors for intervention component delivery via focus groups with providers (n=15) and patients eligible for PrEP (n=30). Then, four intervention components will be tested in an optimization trial, with 16 conditions being implemented at 32 clinics. Finally, feedback will be generated on the factors that affected implementation via semi-structured interviews with providers (n=30) and patients (n=30). Participants will be primary care providers (PCPs) and patients eligible for PrEP in Henry Ford Health System. Clinics will be randomized (yes/no) to receive any combination of provider and patient intervention components. Provider intervention components include computer-based simulation training and/or best practice alerts delivered via the electronic health record (EHR). Patient intervention components include HIV risk assessment and/or PrEP informational video - both delivered via the EHR. Primary outcome is the rate of new PrEP prescriptions at the clinic level. Secondary outcomes will include PrEP maintenance, number of HIV tests ordered by a PCP, and number of PCPs trained. Sub analyses will test which factors moderate (e.g., patient sex, race, age, gender, sexual orientation) or mediate (e.g., perceived HIV risk, provider and patient PrEP knowledge) PrEP uptake, focusing on priority populations and disparities in rates of PrEP prescription. Implications: 1) Understanding which intervention components lead to increased PrEP prescriptions will represent an important advance in HIV prevention efforts. 2) Optimizing a multi-level intervention for providers and patients to increase PrEP prescriptions would lead to a new, efficient, evidence-based option. 3) Determining what factors are related to PrEP uptake will help reduce disparities in PrEP initiation among those most in need. 4) Understanding the context specific factors related to intervention component implementation will help identify best methods for replication/adaptation in other healthcare systems.
Read the detailed description
Inclusion criteria for provider participants are: 1) ≥ 18-years old; 2) employed at HFH in primary care, family medicine, or internal medicine; 3) eligible to write prescriptions in the state of MI.
Inclusion criteria for patient participants are: 1) ≥ 18 years old; 2) have an appointment with a Henry Ford primary care clinic during the study period; 3) have an electronic health record (EHR) account; 4) eligible for PrEP prescription.
Exclusion criteria for providers are: 1) not a HFH primary care provider; 2) does not have prescribing privileges in the state of Michigan.
Exclusion criteria for patient participants include: 1) currently prescribed or taking PrEP; 2) living with HIV.
- Conditions
- HIV Seropositivity
- Being tested
- Computer-based simulation training for providers, Best Practice Alert, HIV Risk Assessment, PrEP Informational Video
- Keywords
- Preexposure Prophylaxis
- Medical subject headings
- HIV Seropositivity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Computer-based simulation training for providersBehavioural
A Computer-Based Simulation training for providers, based on the Centers for Disease Control and Prevention "Guide for Healthcare Professional: Discussing Sexual Health with Your Patients", current PrEP information, and the Social Cognitive Theory. This is a single-session, 30-minute training module contains educational information with animated narration about PrEP, how to take a sexual health history, understanding internal bias, potential patient barriers to PrEP as well as recorded video-simulated encounters, in which providers view different types of patient/provider interactions.
Best Practice AlertBehavioural
A Best Practice Alert will alert providers to patients who are part of the Centers for Disease Control and Prevention PrEP priority populations.
HIV Risk AssessmentBehavioural
A risk assessment tool that considers the behaviors - i.e., types of sexual activities, protective behaviors (condoms, PrEP, ART), and other factors (HIV status, sexually transmitted infections) of the respondent.
PrEP Informational VideoBehavioural
A short informational video, tailored to the local Detroit context with themes that will focus on introducing PrEP, stigma surrounding taking PrEP, and potential barriers and how to overcome them.
| Study group | Role | What they receive |
|---|---|---|
| No intervention | No intervention | No intervention |
| Video | Experimental | Patient PrEP Video only Receives: Behavioral: PrEP Informational Video |
| Risk Assessment | Experimental | Patient Risk Assessment only Receives: Behavioral: HIV Risk Assessment |
| Risk Assessment and Video | Experimental | Patient Risk Assessment and Patient PrEP Video Receives: Behavioral: HIV Risk Assessment; Behavioral: PrEP Informational Video |
| Best Practice Alert | Experimental | Best Practice Alert only Receives: Behavioral: Best Practice Alert |
| Best Practice Alert and Video | Experimental | Best Practice Alert and Patient PrEP Video Receives: Behavioral: Best Practice Alert; Behavioral: PrEP Informational Video |
| Best Practice Alert and Risk Assessment | Experimental | Best Practice Alert and Patient Risk Assessment Receives: Behavioral: Best Practice Alert |
| Best Practice Alert, Risk Assessment and Video | Experimental | Best Practice Alert, Patient Risk Assessment, and Patient PrEP Video Receives: Behavioral: Best Practice Alert; Behavioral: HIV Risk Assessment; Behavioral: PrEP Informational Video |
| Training | Experimental | Provider Training Receives: Behavioral: Computer-based simulation training for providers |
| Training and Video | Experimental | Provider Training and Patient PrEP Video Receives: Behavioral: Computer-based simulation training for providers; Behavioral: PrEP Informational Video |
| Training and Risk Assessment | Experimental | Provider Training and Patient Risk Assessment Receives: Behavioral: Computer-based simulation training for providers; Behavioral: HIV Risk Assessment |
| Training, Risk Assessment, and Video | Experimental | Provider Training, Patient Risk Assessment, and Patient PrEP Video Receives: Behavioral: Computer-based simulation training for providers; Behavioral: HIV Risk Assessment; Behavioral: PrEP Informational Video |
| Training and Best Practice Alert | Experimental | Provider Training and Best Practice Alert Receives: Behavioral: Computer-based simulation training for providers; Behavioral: Best Practice Alert |
| Training, Best Practice Alert, and Video | Experimental | Provider Training, Best Practice Alert, and Patient PrEP Video Receives: Behavioral: Computer-based simulation training for providers; Behavioral: Best Practice Alert; Behavioral: PrEP Informational Video |
| Training, Best Practice Alert, and Risk Assessment | Experimental | Provider Training, Best Practice Alert, and Patient Risk Assessment Receives: Behavioral: Computer-based simulation training for providers; Behavioral: Best Practice Alert; Behavioral: HIV Risk Assessment |
| Training, Best Practice Alert, Risk Assessment, and Video | Experimental | Provider Training, Best Practice Alert, Patient Risk Assessment, and Patient PrEP Video Receives: Behavioral: Computer-based simulation training for providers; Behavioral: Best Practice Alert; Behavioral: HIV Risk Assessment; Behavioral: PrEP Informational Video |
What is being measured
The primary outcome is the main question the study is designed to answer.
Clinic-Level PrEP Prescription
The number of new PrEP prescriptions written within 6-months of the study-associated patient appointment. It is defined as a new documented prescription in the patient electronic health records for PrEP (daily pill or injection) at any date between the initial study primary care appointment plus 180 days.
Measured: Year 1 and Year 5 electronic health record data pull.
Secondary outcomes (4)
PrEP Knowledge
PrEP knowledge will be measured by 6-items assessing PrEP dosing frequency, approved FDA medications, HIV antibody testing prior to PrEP initiation, HIV testing frequency while on PrEP, contraindications to prescribing PrEP, and routine standard of care practices for patients taking PrEP
Measured: Provider pre-post survey and patient demographic and 6- month surveys
PrEP awareness
PrEP awareness will be measured by the statement "there is a pill (drug/medication) that a person can take to prevent transmission of HIV from an infected (HIV positive) sex partner to an uninfected (HIV negative) partner." with responses true/false, don't know.
Measured: Provider pre-post survey and patient demographic and 6- month surveys
PrEP prescribing comfort
PrEP prescribing comfort will be measured by 9- items from the PrEP Information, Motivation, and Behaviors survey.
Measured: Pre-intervention and immediately after the intervention for providers
PrEP prescribing intentions
PrEP prescribing intentions will be measured by 8- items from the PrEP Information, Motivation, and Behaviors survey.
Measured: Pre-intervention and immediately after the intervention for providers
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Mar 2024
- Study start19 Jun 2024
- Primary completion3 Apr 2028 (estimated)
- Study completion30 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HIV SeropositivityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind
- Who is masked
- Participant, Care provider
- Enrolment
- 1,380 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Henry Ford Health System
- Sponsor type
- University, hospital or other
- Collaborators
- University of South Florida, New York University
- Responsible party
- Principal investigator, Elizabeth Lockhart, Henry Ford Health System
- Investigators
- Elizabeth Lockhart, PhD, Principal investigator, Henry Ford Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06334341
- Sponsor's protocol ID
- R01MD018523-01A1
- Acronym
- MOST:PrEP
- Status last verified
- May 2026
- First submitted
- 18 Mar 2024
- Last updated
- 21 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Multilevel, Multiphase Optimization Strategy for PrEP: Patients and Providers in Primary Care
- ClinicalTrials.gov ID
- NCT06334341
- Acronym / sponsor ID
- MOST:PrEP / R01MD018523-01A1
- Conditions
- HIV Seropositivity
- Keywords
- Preexposure Prophylaxis
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 1,380 participants (estimated)
- Lead sponsor
- Henry Ford Health SystemUniversity, hospital or other
- Collaborators
- University of South Florida, New York University
- Study start
- 19 Jun 2024 (actual)
- Primary completion
- 3 Apr 2028 (estimated)
- Study completion
- 30 Jun 2028 (estimated)
- First posted
- 28 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
What is known: There are 1.2 million people in the US who meet the indications for PrEP; yet, disparities exist in uptake. For example, only 9% of Black and 16% of Latino individuals, compared to 65% of White individuals, have been prescribed PrEP. At Henry Ford Health (HFH) system, only 10% of eligible patients have been prescribed PrEP. Primary care is an ideal setting for PrEP to be offered as an HIV prevention method since providers see large numbers of patients who are HIV negative, with some who are at increased risk for HIV, and the primary care setting is often the point of entry to the healthcare system. The multiphase optimization strategy (MOST) framework is a novel, innovative way to identify an efficient intervention. What will be done: In this optimization trial, the investigators will test the effectiveness of intervention components, alone and in combination, on new PrEP prescriptions in primary care at HFH. First, feedback will be generated on context-specific (system and individual level) factors for intervention component delivery via focus groups with providers (n=15) and patients eligible for PrEP (n=30). Then, four intervention components will be tested in an optimization trial, with 16 conditions being implemented at 32 clinics. Finally, feedback will be generated on the factors that affected implementation via semi-structured interviews with providers (n=30) and patients (n=30). Participants will be primary care providers (PCPs) and patients eligible for PrEP in Henry Ford Health System. Clinics will be randomized (yes/no) to receive any combination of provider and patient intervention components. Provider intervention components include computer-based simulation training and/or best practice alerts delivered via the electronic health record (EHR). Patient intervention components include HIV risk assessment and/or PrEP informational video - both delivered via the EHR. Primary outcome is the rate of new PrEP prescriptions at the clinic level. Secondary outcomes will include PrEP maintenance, number of HIV tests ordered by a PCP, and number of PCPs trained. Sub analyses will test which factors moderate (e.g., patient sex, race, age, gender, sexual orientation) or mediate (e.g., perceived HIV risk, provider and patient PrEP knowledge) PrEP uptake, focusing on priority populations and disparities in rates of PrEP prescription. Implications: 1) Understanding which intervention components lead to increased PrEP prescriptions will represent an important advance in HIV prevention efforts. 2) Optimizing a multi-level intervention for providers and patients to increase PrEP prescriptions would lead to a new, efficient, evidence-based option. 3) Determining what factors are related to PrEP uptake will help reduce disparities in PrEP initiation among those most in need. 4) Understanding the context specific factors related to intervention component implementation will help identify best methods for replication/adaptation in other healthcare systems.
Detailed description
Inclusion criteria for provider participants are: 1) ≥ 18-years old; 2) employed at HFH in primary care, family medicine, or internal medicine; 3) eligible to write prescriptions in the state of MI.
Inclusion criteria for patient participants are: 1) ≥ 18 years old; 2) have an appointment with a Henry Ford primary care clinic during the study period; 3) have an electronic health record (EHR) account; 4) eligible for PrEP prescription.
Exclusion criteria for providers are: 1) not a HFH primary care provider; 2) does not have prescribing privileges in the state of Michigan.
Exclusion criteria for patient participants include: 1) currently prescribed or taking PrEP; 2) living with HIV.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Factorial
- Masking
- Double blind (participant, care provider)
- Number of arms
- 16
| Arm | Type | Receives |
|---|---|---|
| No intervention | No intervention | –No intervention |
| Video | Experimental | Behavioral: PrEP Informational VideoPatient PrEP Video only |
| Risk Assessment | Experimental | Behavioral: HIV Risk AssessmentPatient Risk Assessment only |
| Risk Assessment and Video | Experimental | Behavioral: HIV Risk Assessment, Behavioral: PrEP Informational VideoPatient Risk Assessment and Patient PrEP Video |
| Best Practice Alert | Experimental | Behavioral: Best Practice AlertBest Practice Alert only |
| Best Practice Alert and Video | Experimental | Behavioral: Best Practice Alert, Behavioral: PrEP Informational VideoBest Practice Alert and Patient PrEP Video |
| Best Practice Alert and Risk Assessment | Experimental | Behavioral: Best Practice AlertBest Practice Alert and Patient Risk Assessment |
| Best Practice Alert, Risk Assessment and Video | Experimental | Behavioral: Best Practice Alert, Behavioral: HIV Risk Assessment, Behavioral: PrEP Informational VideoBest Practice Alert, Patient Risk Assessment, and Patient PrEP Video |
| Training | Experimental | Behavioral: Computer-based simulation training for providersProvider Training |
| Training and Video | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: PrEP Informational VideoProvider Training and Patient PrEP Video |
| Training and Risk Assessment | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: HIV Risk AssessmentProvider Training and Patient Risk Assessment |
| Training, Risk Assessment, and Video | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: HIV Risk Assessment, Behavioral: PrEP Informational VideoProvider Training, Patient Risk Assessment, and Patient PrEP Video |
| Training and Best Practice Alert | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: Best Practice AlertProvider Training and Best Practice Alert |
| Training, Best Practice Alert, and Video | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: Best Practice Alert, Behavioral: PrEP Informational VideoProvider Training, Best Practice Alert, and Patient PrEP Video |
| Training, Best Practice Alert, and Risk Assessment | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: Best Practice Alert, Behavioral: HIV Risk AssessmentProvider Training, Best Practice Alert, and Patient Risk Assessment |
| Training, Best Practice Alert, Risk Assessment, and Video | Experimental | Behavioral: Computer-based simulation training for providers, Behavioral: Best Practice Alert, Behavioral: HIV Risk Assessment, Behavioral: PrEP Informational VideoProvider Training, Best Practice Alert, Patient Risk Assessment, and Patient PrEP Video |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (7 listed)
- Provider:≥ 18-years old
- Provider: employed at HFH as a primary care provider
- Provider: eligible to write prescriptions in the state of Michigan
- Patient: ≥ 18 years old
- Patient: have an appointment with a Henry Ford primary care clinic during the study period
Key exclusion criteria (4 listed)
- Provider: not a HFH primary care provider
- Provider: does not have prescribing privileges in the state of Michigan
- Patient: currently prescribed or taking PrEP
- Patient: living with HIV
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Computer-based simulation training for providersA Computer-Based Simulation training for providers, based on the Centers for Disease Control and Prevention "Guide for Healthcare Professional: Discussing Sexual Health with Your Patients", current PrEP information, and the Social Cognitive Theory. This is a single-session, 30-minute training module contains educational information with animated narration about PrEP, how to take a sexual health history, understanding internal bias, potential patient barriers to PrEP as well as recorded video-simulated encounters, in which providers view different types of patient/provider interactions. | Behavioural | Training, Training and Best Practice Alert, Training and Risk Assessment, Training and Video, Training, Best Practice Alert, Risk Assessment, and Video, Training, Best Practice Alert, and Risk Assessment, Training, Best Practice Alert, and Video, Training, Risk Assessment, and Video |
| Best Practice AlertA Best Practice Alert will alert providers to patients who are part of the Centers for Disease Control and Prevention PrEP priority populations. | Behavioural | Best Practice Alert, Best Practice Alert and Risk Assessment, Best Practice Alert and Video, Best Practice Alert, Risk Assessment and Video, Training and Best Practice Alert, Training, Best Practice Alert, Risk Assessment, and Video, Training, Best Practice Alert, and Risk Assessment, Training, Best Practice Alert, and Video |
| HIV Risk AssessmentA risk assessment tool that considers the behaviors - i.e., types of sexual activities, protective behaviors (condoms, PrEP, ART), and other factors (HIV status, sexually transmitted infections) of the respondent. | Behavioural | Best Practice Alert, Risk Assessment and Video, Risk Assessment, Risk Assessment and Video, Training and Risk Assessment, Training, Best Practice Alert, Risk Assessment, and Video, Training, Best Practice Alert, and Risk Assessment, Training, Risk Assessment, and Video |
| PrEP Informational VideoA short informational video, tailored to the local Detroit context with themes that will focus on introducing PrEP, stigma surrounding taking PrEP, and potential barriers and how to overcome them. | Behavioural | Best Practice Alert and Video, Best Practice Alert, Risk Assessment and Video, Risk Assessment and Video, Training and Video, Training, Best Practice Alert, Risk Assessment, and Video, Training, Best Practice Alert, and Video, Training, Risk Assessment, and Video, Video |
Primary outcome
Clinic-Level PrEP Prescription
Time frame: Year 1 and Year 5 electronic health record data pull.
The number of new PrEP prescriptions written within 6-months of the study-associated patient appointment. It is defined as a new documented prescription in the patient electronic health records for PrEP (daily pill or injection) at any date between the initial study primary care appointment plus 180 days.
4 secondary outcomes
PrEP Knowledge
Time frame: Provider pre-post survey and patient demographic and 6- month surveys
PrEP awareness
Time frame: Provider pre-post survey and patient demographic and 6- month surveys
PrEP prescribing comfort
Time frame: Pre-intervention and immediately after the intervention for providers
PrEP prescribing intentions
Time frame: Pre-intervention and immediately after the intervention for providers
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Elizabeth Lockhart, PhD principal investigator
Henry Ford Health
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Computer-based simulation training for providers, Best Practice Alert and HIV Risk Assessment in people with HIV Seropositivity, run by Henry Ford Health System at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 21 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Clinic-Level PrEP Prescription (time frame: Year 1 and Year 5 electronic health record data pull.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Sep 2026.