Echinococcosis, HepaticPAFCLENCT06316154
Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis
An observational study of Echinococcosis, Hepatic, run by Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov at 1 site in Uzbekistan.
Trial summary
The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Echinococcosis, Hepatic
- What is being tested?
- Echinococcectomy
- Type of treatment
- Pill or oral medicine, Surgery or procedure
- How many people
- 100 participants
- Where
- 1 siteUzbekistan
- Study dates
- 22 Oct 2023to 25 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with primary or recurrent liver echinococcosis
Who may be able to join
- Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment
- Cyst diametr >5 cm;
- Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research;
- Signed informed consent of patients for inclusion in the study;
Who cannot join
- Liver echinococcosis with cysts less than 5 cm in diametr;
- Presence of severe concomitant disorders
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Uzbekistan1 site, 1 recruiting
- Recruiting
Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov
Tashkent, Uzbekistan, 100115
Azam Babadjanov, Professor, +998901751703, azam746@mail.ru
About this study
Official title: Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis During Organ-preserving Surgery
The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.
- Conditions
- Echinococcosis, Hepatic
- Being tested
- Echinococcectomy
- Medical subject headings
- Echinococcosis, Hepatic
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
EchinococcectomyProcedure or surgery
Echinococcectomy with subsequent pathomorphological analysis of liver parenchyma next to and in the thickness of the fibrous capsule
What is being measured
The primary outcome is the main question the study is designed to answer.
Presence of viable germinal elements of echinococcosis
Identification of viable germinal elements of echinococcosis according to morphological analysis
Measured: 1 day
Secondary outcomes (1)
Recurrence of liver echinococcosis
Identification of frequency of liver echinococcosis in postoperative period
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Mar 2024
- Study start22 Oct 2023
- Primary completion22 Dec 2026 (estimated)
- Study completion25 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Echinococcosis, HepaticStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Azam Babadjanov, Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06316154
- Sponsor's protocol ID
- 12032024
- Acronym
- PAFCLE
- Status last verified
- Sep 2025
- First submitted
- 12 Mar 2024
- Last updated
- 30 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis During Organ-preserving Surgery
- ClinicalTrials.gov ID
- NCT06316154
- Acronym / sponsor ID
- PAFCLE / 12032024
- Conditions
- Echinococcosis, Hepatic
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. VakhidovUniversity, hospital or other
- Study start
- 22 Oct 2023 (actual)
- Primary completion
- 22 Dec 2026 (estimated)
- Study completion
- 25 Dec 2026 (estimated)
- First posted
- 18 Mar 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with primary or recurrent liver echinococcosis
Key inclusion criteria (4 listed)
- Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment
- Cyst diametr >5 cm;
- Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research;
- Signed informed consent of patients for inclusion in the study;
Key exclusion criteria (2 listed)
- Liver echinococcosis with cysts less than 5 cm in diametr;
- Presence of severe concomitant disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| EchinococcectomyEchinococcectomy with subsequent pathomorphological analysis of liver parenchyma next to and in the thickness of the fibrous capsule | Procedure or surgery | – |
Primary outcome
Presence of viable germinal elements of echinococcosis
Time frame: 1 day
Identification of viable germinal elements of echinococcosis according to morphological analysis
1 secondary outcome
Recurrence of liver echinococcosis
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Dec 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov
Tashkent, Uzbekistan
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Echinococcosis, Hepatic, run by Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov at 1 site in Uzbekistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 30 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Uzbekistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Presence of viable germinal elements of echinococcosis (time frame: 1 day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Dec 2025.