Heart FailurePilot-CRHFNCT06269263
Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
A study testing Home-based cardiac rehabilitation in people with Heart Failure, run by University of Leipzig at 1 site in Germany.
Trial summary
The proposed study will determine the willingness of patients for participation. Furthermore, the assessment of tests to identify eligible patients and the type of exercise intervention that goes along with a high patient compliance is crucial. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Heart Failure
- What is being tested?
- Home-based cardiac rehabilitation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteGermany
- Study dates
- 29 Feb 2024to 30 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- Chronic heart failure irrespective of the ejection fraction
- Recent history of acute cardiac decompensation leading to hospitalization
Who cannot join
- Patients not willing to participate
- Patients with orthopedic diseases limiting their mobility
- Cognitive diseases that hinder adequate participation in the opinion of the investigator
- Inpatient rehabilitation.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Pilot Study to Determine Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
The proposed study will determine the willingness of patients for participation. Furthermore, the assessment of tests to identify eligible patients and the type of exercise intervention that goes along with a high patient compliance is crucial. Also, more information about possible factors preventing patients from participating is required. Therefore, if the patient is willing to participate, the investigators will assess patients' medical history, medication and QoL as well as parameters of routine diagnostics (i.e. echocardiography, laboratory testing, MRI). Following, while the in-patient stay due to cardiac decompensation, the investigators will conduct several assessment-tests to determine the physical status, the exercise capacity and the cognitive function. Moreover, physiotherapists will instruct the patients in the exercise program. After discharge from the hospital, physiotherapist will visit the patient at home to instruct them again in the exercises. Then, the patients will conduct the program on their own for a period of 12 weeks. During the exercise period, a doctoral student will visit the patients at home every 3 weeks to check whether they are doing the exercises correctly and to determine whether there are any problems with the program. After the exercise period of 12 weeks, the baseline characteristics will be assessed again at the University Hospital Leipzig.
Read the detailed description
See above
- Conditions
- Heart Failure
- Being tested
- Home-based cardiac rehabilitation
- Medical subject headings
- Heart Failure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Home-based cardiac rehabilitationBehavioural
Guided by physiotherapists, patients will receive different trainings regrading endurance/balance/resistance,/coordination at home
| Study group | Role | What they receive |
|---|---|---|
| Home-based cardiac rehabilitation | Experimental | Home-based cardiac rehabilitation Receives: Behavioral: Home-based cardiac rehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Percentage of patients completing the program
Percentage of patients completing the program
Measured: After 12 weeks
Secondary outcomes (2)
Quality of life by KCCQ
QoL measured by Kansas City Cardiomyopathy Questionnaire (KCCQ). KCCQ measures in values from 0 to 100 with higher values indicating better quality of life
Measured: After 12 weeks
Exercise capacity
Exercise capacity measured by 6-minutes walk test
Measured: After 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Feb 2024
- Study start29 Feb 2024
- Primary completion30 Apr 2025
- Study completion30 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Heart FailureStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Pilot study of home-based cardiac rehabilitation
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Leipzig
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06269263
- Sponsor's protocol ID
- 339/23-ek
- Acronym
- Pilot-CRHF
- Status last verified
- Apr 2026
- First submitted
- 13 Feb 2024
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
Reuser A, Schittenhelm J, Schroder SC, Kandels J, Richter E, Gaal L, Pfister F, Stegmann T, Uhe T, Wachter R. Bridging the post-hospitalization gap: a feasibility study of home-based rehabilitation in decompensated heart failure. ESC Heart Fail. 2026 Feb 3;13(1):xvaf021. doi: 10.1093/eschf/xvaf021.
PubMed 41711697
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pilot Study to Determine Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF)
- ClinicalTrials.gov ID
- NCT06269263
- Acronym / sponsor ID
- Pilot-CRHF / 339/23-ek
- Conditions
- Heart Failure
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- University of LeipzigUniversity, hospital or other
- Study start
- 29 Feb 2024 (actual)
- Primary completion
- 30 Apr 2025 (actual)
- Study completion
- 30 Apr 2025 (actual)
- First posted
- 21 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The proposed study will determine the willingness of patients for participation. Furthermore, the assessment of tests to identify eligible patients and the type of exercise intervention that goes along with a high patient compliance is crucial. Also, more information about possible factors preventing patients from participating is required. Therefore, if the patient is willing to participate, the investigators will assess patients' medical history, medication and QoL as well as parameters of routine diagnostics (i.e. echocardiography, laboratory testing, MRI). Following, while the in-patient stay due to cardiac decompensation, the investigators will conduct several assessment-tests to determine the physical status, the exercise capacity and the cognitive function. Moreover, physiotherapists will instruct the patients in the exercise program. After discharge from the hospital, physiotherapist will visit the patient at home to instruct them again in the exercises. Then, the patients will conduct the program on their own for a period of 12 weeks. During the exercise period, a doctoral student will visit the patients at home every 3 weeks to check whether they are doing the exercises correctly and to determine whether there are any problems with the program. After the exercise period of 12 weeks, the baseline characteristics will be assessed again at the University Hospital Leipzig.
Detailed description
See above
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Pilot study of home-based cardiac rehabilitation
| Arm | Type | Receives |
|---|---|---|
| Home-based cardiac rehabilitation | Experimental | Behavioral: Home-based cardiac rehabilitationHome-based cardiac rehabilitation |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- Chronic heart failure irrespective of the ejection fraction
- Recent history of acute cardiac decompensation leading to hospitalization
Key exclusion criteria (4 listed)
- Patients not willing to participate
- Patients with orthopedic diseases limiting their mobility
- Cognitive diseases that hinder adequate participation in the opinion of the investigator
- Inpatient rehabilitation.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Home-based cardiac rehabilitationGuided by physiotherapists, patients will receive different trainings regrading endurance/balance/resistance,/coordination at home | Behavioural | Home-based cardiac rehabilitation |
Primary outcome
Percentage of patients completing the program
Time frame: After 12 weeks
Percentage of patients completing the program
2 secondary outcomes
Quality of life by KCCQ
Time frame: After 12 weeks
Exercise capacity
Time frame: After 12 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Background: PubMed 41711697Reuser A, Schittenhelm J, Schroder SC, Kandels J, Richter E, Gaal L, Pfister F, Stegmann T, Uhe T, Wachter R. Bridging the post-hospitalization gap: a feasibility study of home-based rehabilitation in decompensated heart failure. ESC Heart Fail. 2026 Feb 3;13(1):xvaf021. doi: 10.1093/eschf/xvaf021.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Home-based cardiac rehabilitation in people with Heart Failure, run by University of Leipzig at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Percentage of patients completing the program (time frame: After 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06269263, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.