AzTrials
AzTrials

SARS-CoV2 InfectionNCT06247059

Reducing Respiratory Virus Transmission in Bangladeshi Classrooms

A study testing Box Fan, UV Germicidal Irradiation Lamp Unit and Combined: Box Fan and UV Germicidal Irradiation Lamp Units in people with SARS-CoV2 Infection and Influenza Viral Infections, run by Stanford University.

Withdrawn

Withdrawn. The study stopped before anyone enrolled.

Official record
Search all trials

Trial summary

This study will test if affordable air cleaning devices (box fans with a filter attached and/or ultraviolet light lamps) installed in classrooms can reduce the number of viral respiratory illnesses schoolchildren experience. Read more about this study

Who is it for?
Ages 9 to 12 yearsHealthy volunteers can take part
What is being tested?
Box Fan, UV Germicidal Irradiation Lamp Unit and Combined: Box Fan and UV Germicidal Irradiation Lamp Units
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
0 participants
Where
No sites listed yet
Study dates
Oct 2025to Jan 2027
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 9 to 12 years
  • All sexes
  • Healthy volunteers accepted
  • Child

Who may be able to join

  • Schoolchildren of Bangladesh Government-run primary schools in Dhaka, Bangladesh ages 9 - 12 years, of all gender identifiers (male, female, transgender, prefer not to designate), without specific ethnic selection amongst standard school children of Bangladesh government schools in Dhaka, Bangladesh.

Who cannot join

  • School children of non-Bangladesh Government-run primary schools and/or schoolchildren who do not attend a Bangladesh Government-run primary school in Dhaka, Bangladesh.
  • School children who are not able to or have a contraindication with the ability to comply with study procedures.

About this study

This study will test if affordable air cleaning devices (box fans with a filter attached and/or ultraviolet light lamps) installed in classrooms can reduce the number of viral respiratory illnesses schoolchildren experience.

Read the detailed description

This cluster-randomized controlled trial in Bangladesh schools will examine whether low-cost air filtration and/or human-safe ultraviolet germicidal light interventions can reduce the incidence of schoolchildren's respiratory viral infections. The main study objectives are:

  1. Pilot and optimize an intervention to filter classroom air.
  2. Pilot and optimize an intervention to treat classroom air with ultraviolet light.
  3. Assess the separate and combined effect of air filtration and ultraviolet light on the incidence of polymerase chain reaction (PCR) confirmed illness from respiratory viruses.

Methods: The study will take place in 60 government primary schools in Dhaka, Bangladesh. Within each enrolled school, 5 classrooms of students in grades 3, 4 and 5 will be randomly assigned to receive:

  1. Box fans with a filter attachment.
  2. 220 nanometer (nm) wavelength ultraviolet light air cleaner lamps.
  3. Both the box fans with a filter and the 220 nm ultraviolet lamps.
  4. No device: a control group that receives no additional device ("standard of care"). Two classrooms within each school will be assigned as controls.

Why does this matter?: Clarifying the impact of low-cost practical solutions could support the adoption of these strategies that could reduce influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in schools in order to reduce the burden of respiratory illness in these communities.

Being tested
Box Fan, UV Germicidal Irradiation Lamp Unit, Combined: Box Fan and UV Germicidal Irradiation Lamp Units
Keywords
Bangladesh, Indoor air quality, Air cleaning, Respiratory viral infections, Influenza, SARS-CoV2, Air filtration, Ultraviolet germicidal irradiation, Global health
Medical subject headings
COVID-19, Influenza, Human

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Box FanDevice

    Classrooms assigned to this arm will be equipped with 2 - 8 box fans each with a single minimum efficiency reporting value-14 (MERV-14) filter sufficient to increase effective air changes per hour to 12 based on the clean air delivery rate measured in cubic feet per minute of the box fan + filter * 60 divided by the room volume.

  • UV Germicidal Irradiation Lamp UnitDevice

    Classrooms assigned to this arm will be equipped with one or two 222nm wavelength light ultraviolet germicidal irradiation lamp units (number of units per classroom based on room volume).

  • Combined: Box Fan and UV Germicidal Irradiation Lamp UnitsDevice

    Classrooms assigned to this arm will be equipped with both box fans and UV germicidal irradiation lamp units.

Study groups in NCT06247059
Study groupRoleWhat they receive
Box FanExperimentalClassrooms receive box fans equipped with a filter.
Receives: Device: Box Fan
UV Germicidal Irradiation Lamp UnitExperimentalClassrooms receive UV germicidal irradiation lamp unit(s).
Receives: Device: UV Germicidal Irradiation Lamp Unit
Combined: Box Fan and UV Germicidal Irradiation Lamp UnitsExperimentalClassrooms receive box fans equipped with a filter and UV germicidal irradiation lamp unit(s).
Receives: Device: Combined: Box Fan and UV Germicidal Irradiation Lamp Units
Non-Interventional ControlNo interventionClassrooms receive no intervention to their standard classroom setup.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Total number of symptomatic respiratory illness episodes due to either Influenza or SARS- CoV-2

    Study personnel will visit each school twice weekly. They will identify any students within the study classrooms who were absent or who have symptoms consistent with the World Health Organization (WHO) definition of influenza like illness. For children who were absent or who have symptoms, study personnel will visit the child's home, and if the student's parent provides informed consent, collect more detailed information on signs and symptoms, and a throat swab from the child. The throat swab will be placed on viral transport media, placed on ice and transported to the One Health Laboratory at the International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b). One aliquot from the specimen will be analyzed for Influenza A, Influenza B, and SARS-CoV-2. In the laboratory, nucleic acid in the throat swab specimen will be extracted and one-step real-time (RT)-PCR conducted to assess the presence of RNA from Influenza A, Influenza B or SARS-CoV-2.

    Measured: Over 40 weeks of observation

Secondary outcomes (4)

  1. Total number of symptomatic influenza-like illness episodes

    Study personnel will visit each school twice weekly. They will identify any students within the study classrooms who were absent or who have symptoms consistent with the WHO definition of influenza like illness.

    Measured: Over 40 weeks of observation

  2. Total number of symptomatic influenza episodes

    Study personnel will visit each school twice weekly. They will identify any students within the study classrooms who were absent or who have symptoms consistent with the WHO definition of influenza like illness. For children who were absent or who have symptoms, study personnel will visit the child's home, and if the student's parent provides informed consent, collect more detailed information on signs and symptoms, and a throat swab from the child. The throat swab will be placed on viral transport media, placed on ice and transported to the One Health Laboratory at icddr,b. One aliquot from the specimen will be analyzed for Influenza A or Influenza B. In the laboratory, nucleic acid in the throat swab specimen will be extracted and one-step real-time RT-PCR conducted to assess the presence of RNA from Influenza A or Influenza B.

    Measured: Over 40 weeks of observation

  3. Total number of symptomatic SARS-CoV2 episodes

    Study personnel will visit each school twice weekly. They will identify any students within the study classrooms who were absent or who have symptoms consistent with the WHO definition of influenza like illness. For children who were absent or who have symptoms, study personnel will visit the child's home, and if the student's parent provides informed consent, collect more detailed information on signs and symptoms, and a throat swab from the child. The throat swab will be placed on viral transport media, placed on ice and transported to the One Health Laboratory at icddr,b. One aliquot from the specimen will be analyzed for SARS-CoV2. In the laboratory, nucleic acid in the throat swab specimen will be extracted and one-step real-time RT-PCR conducted to assess the presence of RNA from SARS-CoV2.

    Measured: Over 40 weeks of observation

  4. Total number of student absentee episodes

    Study personnel will visit each school twice weekly. They will identify any students within the study classrooms who were absent.

    Measured: Over 40 weeks of observation

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted7 Feb 2024
  2. Study startOct 2025 (estimated)
  3. Primary completionSep 2026 (estimated)
  4. Study completionJan 2027 (estimated)

Why it stopped: Loss of funding prior to study initiation. No participants were enrolled.

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Prevention
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
0 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06247059
Sponsor's protocol ID
73657
Status last verified
Aug 2026
First submitted
30 Jan 2024
Last updated
24 Aug 2026
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Questions about this trial

What is this clinical trial studying?

A study testing Box Fan, UV Germicidal Irradiation Lamp Unit and Combined: Box Fan and UV Germicidal Irradiation Lamp Units in people with SARS-CoV2 Infection and Influenza Viral Infections, run by Stanford University.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: withdrawn, as of the sponsor's last update on 24 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study was withdrawn before enrolling participants, so there are no results.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Total number of symptomatic respiratory illness episodes due to either Influenza or SARS- CoV-2 (time frame: Over 40 weeks of observation). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06247059.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Aug 2026.

AzTrials uses cookies for analytics and advertising. You can accept or reject them; the site works either way. Privacy Policy.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in