Neck PainNCT06240611
Isokinetic Assessment of Wrist Muscle Performance Among Medical Students With Neck Pain
An observational study of Neck Pain, run by Mohamed Mahmoud Refaey at 1 site in Egypt.
Trial summary
PURPOSES: 1. To assess the effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight among Egyptian physical therapy students. 2. To assess the effect of chronic non-specific neck pain on extensor / flexor wrist ratio among Egyptian physical therapy students. 3. Read more about this study
- Who is it for?
- Ages 18 to 23 yearsHealthy volunteers can take part
- Conditions the study is for
- Neck Pain
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 1 May 2023to 25 Dec 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 23 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: Participants were recruited from the physical therapy outpatients' clinics of Cairo University, and they were assigned into two groups (group A (control group) and group B (experimental group), with a sample size of approximately 44 participants and an anticipated 15% dropout rate (twenty-two in each group) calculated using the G Power test method.
Who may be able to join
- Both sexes
- Duration of neck pain (> 3 months)
- Age from 18 to 23 years
- The neck pain intensity is between 3 and 8 on the Numerical Pain Rating Scale
- Neck pain-related disability was between 5 and 14 points on the Neck Disability Index
- Body mass index from 18.5 to 29.5
Who cannot join
- Neurological conditions (i.e., Parkinson's disease, multiple sclerosis, head injury, peripheral neuropathy, stroke, or nerve root entrapment)
- Headache
- Cancer, infection, or any other illness symptoms.
- Trauma
- Cardiovascular problems or cerebrovascular insufficiency symptoms.
- Musculoskeletal disorder (i.e., joint replacement, amputation, physically limiting arthritis, contractures of fixed deformity, or muscular dystrophy)
Show all 11Show fewer
- Orthopedic or neurological conditions such as fractures, surgeries on the upper limb or hand, carpal tunnel syndrome, De Quervain's syndrome, or diabetic mellitus
- Cervical spine spondylosis, disc prolapse, spinal stenosis, cervical fracture, etc.
- Any recent treatment for neck pain.
- Visual, auditory and speech problems
- Forward head posture.
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Faculty of Physical Therapy, Cairo University
Cairo, Giza Governorate, 12552
About this study
Official title: Isokinetic Assessment of Wrist Muscle Performance Among Egyptian Physical Therapy Students With Chronic Non-Specific Neck Pain
PURPOSES:
- To assess the effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight among Egyptian physical therapy students.
- To assess the effect of chronic non-specific neck pain on extensor / flexor wrist ratio among Egyptian physical therapy students.
- To assess the effect of chronic non-specific neck pain on wrist extensor and flexor muscles endurance among Egyptian physical therapy students.
Read the detailed description
BACKGROUND:
Although it is widely acknowledged that chronic non-specific neck pain is linked to hand disability as previously studied on dentists and ministry of health care stuff, there is still a gap in illustrating the effect of chronic non-specific neck pain on Egyptian physical therapy students' functional ability of wrist in the upper limb. However, the assessment of extensor / flexor wrist strength ratio has only recently gained attention. Furthermore, there is limited research investigating the strength control ratio that incorporates both concentric and eccentric muscle actions, and additional scientific evidence is needed to establish the relationship between chronic non-specific neck pain and upper limb disability. This study will be conducted to set new assessment and rehabilitation goals. This will subsequently be translated into home therapy program, contributing to decrease the burden of neck pain economically and on health care management.
Our study aims to evaluate peak torque of wrist extensor and flexor muscle/ body weight and extensor / flexor wrist ratio and wrist extensor and flexor muscle endurance among Egyptian physical therapy students with non-specific neck pain. Torque results are adjusted for body weight and compared to normative data for the gender and activity specialty to determine whether the unaffected limb is strong enough to act as a reference for the afflicted limb also compared between right- and left-handed subjects.
HYPOTHESES:
- There will be no significant effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight.
- There will be no significant effect of chronic non-specific neck pain on extensor / flexor wrist ratio.
- There will be no significant effect of chronic non-specific neck pain on wrist extensor and flexor muscles endurance.
RESEARCH QUESTIONS:
- Does chronic non-specific neck pain affect wrist extensor and flexor muscles performance among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect peak torque of wrist extensor and flexor muscles/ body weight among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect extensor / flexor wrist ratio among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect wrist extensor and flexor muscles endurance among Egyptian physical therapy students?
- Conditions
- Neck Pain
- Keywords
- Muscle Strength, Muscle Fatigue, Dynamometer, Wrist
- Medical subject headings
- Neck Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Group A (Control) | A healthy matched volunteers' group (n = 23) between 18 and 23 years of age was included in this study. For students of both genders, the body mass index was not less than 18.5 and not more than 29.5, and there was no recent or previous musculoskeletal injury or pain. | |
| Group B (Experimental) | Participants with CNSNP (n = 22) were between 18 and 23 years of age. Patients with CNSNP For students of both genders, the duration of the non-specific neck pain was more than 3 months (for the symptomatic group with no neurological manifestations and with referral from orthopedic surgeons by diagnosis of non-specific neck pain), and for matched students, they did not have any history of neck pain. The student's age ranges from 18 to 23 years. Neck pain intensity on the numerical Pain Rating Scale was between 3 and 8, and neck pain-related disability on the Neck Disability Index was between 5 and 14 points (10-28%) for mild disability and 15-24 points (30-48%) for moderate disability. The body mass index for students was not less than 18.5 and not more than 29.5. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Comparison of the findings of isokinetic dynamometer between control and study groups
peak torque/body weight percentage between control and study groups
Measured: Baseline
The difference between control and study groups in the findings of isokinetic dynamometer
work fatigue index percentage between control and study groups
Measured: Through study completion, an average of 5 months
The correlation between neck pain and the findings of isokinetic dynamometer
agonist/antagonist ratio percentage between control and study groups
Measured: Up to 5 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Feb 2024
- Study start1 May 2023
- Primary completion17 Nov 2023
- Study completion25 Dec 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (9)Papers the sponsor has linked to this study.
- Other trials for Neck PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mohamed Mahmoud Refaey
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Mohamed Mahmoud Refaey, Cairo University
- Investigators
- Enas F Youssef, Dr, Study chair, Department of Musculoskeletal Disorders Faculty of Physical Therapy Cairo UniversityAnees S Gheit, Dr, Study director, Department of Biomechanics, Faculty of Physical Therapy Kafr El Sheikh UniversityAya A Khalil, Principal investigator, Department of Biomechanics, Faculty of Physical Therapy Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06240611
- Sponsor's protocol ID
- neck pain on wrist muscles
- Status last verified
- Jan 2024
- First submitted
- 16 Jan 2024
- Last updated
- 5 Feb 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Alreni AS, Harrop D, Gumber A, McLean S. Measures of upper limb function for people with neck pain: a systematic review of measurement and practical properties (protocol). Syst Rev. 2015 Apr 7;4:43. doi: 10.1186/s13643-015-0034-2.
PubMed 25875810Andrew D, Yielder P, Haavik H, Murphy B. The effects of subclinical neck pain on sensorimotor integration following a complex motor pursuit task. Exp Brain Res. 2018 Jan;236(1):1-11. doi: 10.1007/s00221-017-5103-4. Epub 2017 Oct 12.
PubMed 29026942Alsalameh AM, Harisi MJ, Alduayji MA, Almutham AA, Mahmood FM. Evaluating the relationship between smartphone addiction/overuse and musculoskeletal pain among medical students at Qassim University. J Family Med Prim Care. 2019 Sep 30;8(9):2953-2959. doi: 10.4103/jfmpc.jfmpc_665_19. eCollection 2019 Sep.
PubMed 31681674Ajimsha MS, Shenoy PD, Gampawar N. Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review. J Bodyw Mov Ther. 2020 Oct;24(4):423-431. doi: 10.1016/j.jbmt.2020.07.020. Epub 2020 Jul 30.
PubMed 33218543de la Motte SJ, Gribbin TC, Lisman P, Murphy K, Deuster PA. Systematic Review of the Association Between Physical Fitness and Musculoskeletal Injury Risk: Part 2-Muscular Endurance and Muscular Strength. J Strength Cond Res. 2017 Nov;31(11):3218-3234. doi: 10.1519/JSC.0000000000002174.
PubMed 28796127Gane EM, McPhail SM, Hatton AL, Panizza BJ, O'Leary SP. The relationship between physical impairments, quality of life and disability of the neck and upper limb in patients following neck dissection. J Cancer Surviv. 2018 Oct;12(5):619-631. doi: 10.1007/s11764-018-0697-5. Epub 2018 May 16.
PubMed 29770954Ortego G, Lluch E, Herrero P, Boudreau SA, Domenech-Garcia V. Profiling and Association over Time between Disability and Pain Features in Patients with Chronic Nonspecific Neck Pain: A Longitudinal Study. J Clin Med. 2022 Feb 28;11(5):1346. doi: 10.3390/jcm11051346.
PubMed 35268437Stenner HT, Eigendorf J, Kerling A, Kueck M, Hanke AA, Boyen J, Nelius AK, Melk A, Boethig D, Bara C, Hilfiker A, Berliner D, Bauersachs J, Hilfiker-Kleiner D, Eberhard J, Stiesch M, Schippert C, Haverich A, Tegtbur U, Haufe S. Effects of six month personalized endurance training on work ability in middle-aged sedentary women: a secondary analysis of a randomized controlled trial. J Occup Med Toxicol. 2020 May 6;15:8. doi: 10.1186/s12995-020-00261-4. eCollection 2020.
PubMed 32391068Refaey MM, Youssef EF, Gheit AS, Emam MA, Khalil AAM. Wrist muscle performance in students with chronic nonspecific neck pain: an isokinetic assessment. BMC Musculoskelet Disord. 2026 Mar 18;27(1):294. doi: 10.1186/s12891-026-09730-z.
PubMed 41851862
Study at a glance
From the registry record, last updated by the sponsor on 5 Feb 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Isokinetic Assessment of Wrist Muscle Performance Among Egyptian Physical Therapy Students With Chronic Non-Specific Neck Pain
- ClinicalTrials.gov ID
- NCT06240611
- Acronym / sponsor ID
- neck pain on wrist muscles
- Conditions
- Neck Pain
- Keywords
- Muscle Strength, Muscle Fatigue, Dynamometer, Wrist
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Mohamed Mahmoud RefaeyUniversity, hospital or other
- Study start
- 1 May 2023 (actual)
- Primary completion
- 17 Nov 2023 (actual)
- Study completion
- 25 Dec 2023 (actual)
- First posted
- 5 Feb 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
PURPOSES:
- To assess the effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight among Egyptian physical therapy students.
- To assess the effect of chronic non-specific neck pain on extensor / flexor wrist ratio among Egyptian physical therapy students.
- To assess the effect of chronic non-specific neck pain on wrist extensor and flexor muscles endurance among Egyptian physical therapy students.
Detailed description
BACKGROUND:
Although it is widely acknowledged that chronic non-specific neck pain is linked to hand disability as previously studied on dentists and ministry of health care stuff, there is still a gap in illustrating the effect of chronic non-specific neck pain on Egyptian physical therapy students' functional ability of wrist in the upper limb. However, the assessment of extensor / flexor wrist strength ratio has only recently gained attention. Furthermore, there is limited research investigating the strength control ratio that incorporates both concentric and eccentric muscle actions, and additional scientific evidence is needed to establish the relationship between chronic non-specific neck pain and upper limb disability. This study will be conducted to set new assessment and rehabilitation goals. This will subsequently be translated into home therapy program, contributing to decrease the burden of neck pain economically and on health care management.
Our study aims to evaluate peak torque of wrist extensor and flexor muscle/ body weight and extensor / flexor wrist ratio and wrist extensor and flexor muscle endurance among Egyptian physical therapy students with non-specific neck pain. Torque results are adjusted for body weight and compared to normative data for the gender and activity specialty to determine whether the unaffected limb is strong enough to act as a reference for the afflicted limb also compared between right- and left-handed subjects.
HYPOTHESES:
- There will be no significant effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight.
- There will be no significant effect of chronic non-specific neck pain on extensor / flexor wrist ratio.
- There will be no significant effect of chronic non-specific neck pain on wrist extensor and flexor muscles endurance.
RESEARCH QUESTIONS:
- Does chronic non-specific neck pain affect wrist extensor and flexor muscles performance among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect peak torque of wrist extensor and flexor muscles/ body weight among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect extensor / flexor wrist ratio among Egyptian physical therapy students?
- Does chronic non-specific neck pain affect wrist extensor and flexor muscles endurance among Egyptian physical therapy students?
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A (Control) | – | –A healthy matched volunteers' group (n = 23) between 18 and 23 years of age was included in this study. For students of both genders, the body mass index was not less than 18.5 and not more than 29.5, and there was no recent or previous musculoskeletal injury or pain. |
| Group B (Experimental) | – | –Participants with CNSNP (n = 22) were between 18 and 23 years of age. Patients with CNSNP For students of both genders, the duration of the non-specific neck pain was more than 3 months (for the symptomatic group with no neurological manifestations and with referral from orthopedic surgeons by diagnosis of non-specific neck pain), and for matched students, they did not have any history of neck pain. The student's age ranges from 18 to 23 years. Neck pain intensity on the numerical Pain Rating Scale was between 3 and 8, and neck pain-related disability on the Neck Disability Index was between 5 and 14 points (10-28%) for mild disability and 15-24 points (30-48%) for moderate disability. The body mass index for students was not less than 18.5 and not more than 29.5. |
Who may qualify
- Ages
- 18 to 23 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- Participants were recruited from the physical therapy outpatients' clinics of Cairo University, and they were assigned into two groups (group A (control group) and group B (experimental group), with a sample size of approximately 44 participants and an anticipated 15% dropout rate (twenty-two in each group) calculated using the G Power test method.
Key inclusion criteria (6 listed)
- Both sexes
- Duration of neck pain (> 3 months)
- Age from 18 to 23 years
- The neck pain intensity is between 3 and 8 on the Numerical Pain Rating Scale
- Neck pain-related disability was between 5 and 14 points on the Neck Disability Index
Key exclusion criteria (11 listed)
- Neurological conditions (i.e., Parkinson's disease, multiple sclerosis, head injury, peripheral neuropathy, stroke, or nerve root entrapment)
- Headache
- Cancer, infection, or any other illness symptoms.
- Trauma
- Cardiovascular problems or cerebrovascular insufficiency symptoms.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Comparison of the findings of isokinetic dynamometer between control and study groups
Time frame: Baseline
peak torque/body weight percentage between control and study groups
The difference between control and study groups in the findings of isokinetic dynamometer
Time frame: Through study completion, an average of 5 months
work fatigue index percentage between control and study groups
The correlation between neck pain and the findings of isokinetic dynamometer
Time frame: Up to 5 months
agonist/antagonist ratio percentage between control and study groups
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Feb 2024.
- Results publication: PubMed 25875810Alreni AS, Harrop D, Gumber A, McLean S. Measures of upper limb function for people with neck pain: a systematic review of measurement and practical properties (protocol). Syst Rev. 2015 Apr 7;4:43. doi: 10.1186/s13643-015-0034-2.
- Results publication: PubMed 29026942Andrew D, Yielder P, Haavik H, Murphy B. The effects of subclinical neck pain on sensorimotor integration following a complex motor pursuit task. Exp Brain Res. 2018 Jan;236(1):1-11. doi: 10.1007/s00221-017-5103-4. Epub 2017 Oct 12.
- Results publication: PubMed 31681674Alsalameh AM, Harisi MJ, Alduayji MA, Almutham AA, Mahmood FM. Evaluating the relationship between smartphone addiction/overuse and musculoskeletal pain among medical students at Qassim University. J Family Med Prim Care. 2019 Sep 30;8(9):2953-2959. doi: 10.4103/jfmpc.jfmpc_665_19. eCollection 2019 Sep.
- Results publication: PubMed 33218543Ajimsha MS, Shenoy PD, Gampawar N. Role of fascial connectivity in musculoskeletal dysfunctions: A narrative review. J Bodyw Mov Ther. 2020 Oct;24(4):423-431. doi: 10.1016/j.jbmt.2020.07.020. Epub 2020 Jul 30.
- Results publication: PubMed 28796127de la Motte SJ, Gribbin TC, Lisman P, Murphy K, Deuster PA. Systematic Review of the Association Between Physical Fitness and Musculoskeletal Injury Risk: Part 2-Muscular Endurance and Muscular Strength. J Strength Cond Res. 2017 Nov;31(11):3218-3234. doi: 10.1519/JSC.0000000000002174.
- Results publication: PubMed 29770954Gane EM, McPhail SM, Hatton AL, Panizza BJ, O'Leary SP. The relationship between physical impairments, quality of life and disability of the neck and upper limb in patients following neck dissection. J Cancer Surviv. 2018 Oct;12(5):619-631. doi: 10.1007/s11764-018-0697-5. Epub 2018 May 16.
- Results publication: PubMed 35268437Ortego G, Lluch E, Herrero P, Boudreau SA, Domenech-Garcia V. Profiling and Association over Time between Disability and Pain Features in Patients with Chronic Nonspecific Neck Pain: A Longitudinal Study. J Clin Med. 2022 Feb 28;11(5):1346. doi: 10.3390/jcm11051346.
- Results publication: PubMed 32391068Stenner HT, Eigendorf J, Kerling A, Kueck M, Hanke AA, Boyen J, Nelius AK, Melk A, Boethig D, Bara C, Hilfiker A, Berliner D, Bauersachs J, Hilfiker-Kleiner D, Eberhard J, Stiesch M, Schippert C, Haverich A, Tegtbur U, Haufe S. Effects of six month personalized endurance training on work ability in middle-aged sedentary women: a secondary analysis of a randomized controlled trial. J Occup Med Toxicol. 2020 May 6;15:8. doi: 10.1186/s12995-020-00261-4. eCollection 2020.
- Derived from this study: PubMed 41851862Refaey MM, Youssef EF, Gheit AS, Emam MA, Khalil AAM. Wrist muscle performance in students with chronic nonspecific neck pain: an isokinetic assessment. BMC Musculoskelet Disord. 2026 Mar 18;27(1):294. doi: 10.1186/s12891-026-09730-z.
- Individual participant dataSharing planned: Undecided
Related trials for Neck Pain
Not yet recruiting
Effects of Whole-Body Vibration and Cervical Stabilization With Core Stabilization in Young Adults With Non-Specific Low Back Pain
Nonspecific Low Back Pain
Recruiting
Strain Counter Strain and Conventional Stretching in School-aged Children With Mechanical Neck Pain Due to Prolong Screen Use
Mechanical Neck Pain
Recruiting
Effects of Alexander Technique Versus Feldenkrais Somatic Training in Patients With Text Neck Syndrome
Text Neck Syndrome
Recruiting
Longitudinal Stripping Massage vs. Percussion Device for Neck Pain: Ultrasound Study.
Chronic Neck Pain
RecruitingPhase 2
Effectiveness of Phenotype-based Pain Management Guidelines for Head and Neck Cancer Related Pain: a Pilot Study
Cancer Pain, Orofacial Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Enas F Youssef, Dr study chair
Department of Musculoskeletal Disorders Faculty of Physical Therapy Cairo University
Anees S Gheit, Dr study director
Department of Biomechanics, Faculty of Physical Therapy Kafr El Sheikh University
Aya A Khalil principal investigator
Department of Biomechanics, Faculty of Physical Therapy Cairo University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Neck Pain, run by Mohamed Mahmoud Refaey at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Feb 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Comparison of the findings of isokinetic dynamometer between control and study groups (time frame: Baseline). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06240611, which also lists 9 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Feb 2024.