Comorbidities and Coexisting ConditionsNCT06209944
Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
An observational study of Comorbidities and Coexisting Conditions and Cardiopulmonary Resuscitation, run by Jane Yidan Zhu at 1 site in China.
Trial summary
The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are: Whether age would affect outcome Whether Charlson Comorbidity Index would affect outcome Whether the conditions… Read more about this study
- Who is it for?
- Ages 65 to 101 years
- Conditions the study is for
- Comorbidities and Coexisting Conditions, Cardiopulmonary Resuscitation, Geriatrics
- What is being tested?
- Cardiopulmonary resuscitation
- Type of treatment
- Surgery or procedure
- How many people
- 394 participants
- Where
- 1 siteChina
- Study dates
- 2 May 2019to 31 Dec 2019
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 to 101 years
- All sexes
- No healthy volunteers
- Older adult
Study population: All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (a regional acute hospital with total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
Who may be able to join
- All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
- In patients with multiple resuscitation events, only the first in-hospital CPR was included.
Who cannot join
- Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
- Patients younger than 65 years old
- Out-of-hospital CPR in the index admission
- CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards
Trial locations and contacts
1 site in 1 country.
About this study
Official title: A Retrospective Review on Charlson Comorbidity Index (CCI) as a Predictor of Return-of-spontaneous-circulation and Survival-to-discharge of Geriatric In-hospital Cardiopulmonary Resuscitation (CPR) in a Regional Acute Hospital in Hong Kong
The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:
- Whether age would affect outcome
- Whether Charlson Comorbidity Index would affect outcome
- Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival.
Researchers would compare the patients who deceased with the patients who survived.
Read the detailed description
The goal of this review was to investigate the impact of age, existing medical conditions. and other factors before cardiac arrest in predicting outcome of in-hospital cardiopulmonary resuscitation (CPR) of older persons.
It was conducted on all patients aged ≥ 65, who underwent CPR in acute medical and geriatric wards (excluding Intensive Care Unit) in United Christian Hospital from January 2017 to December 2018.
- Being tested
- Cardiopulmonary resuscitation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cardiopulmonary resuscitationProcedure or surgery
cardiac compression, endotracheal intubation, defibrillation, and use of cardiovascular medications, to restore circulation in patients with cardiac arrest
What is being measured
The primary outcome is the main question the study is designed to answer.
sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.
Sustained ROSC is defined as documented return of adequate circulation in the absence of ongoing chest compressions, and the duration should be of 20 minutes or above
Measured: 2017 - 2018
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Jan 2024
- Study start2 May 2019
- Primary completion31 Dec 2019
- Study completion31 Dec 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Comorbidities and Coexisting ConditionsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Retrospective
- Enrolment
- 394 participants (actual)
Sponsor and investigators
- Lead sponsor
- Jane Yidan Zhu
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Jane Yidan Zhu, Haven of Hope Hospital
- Investigators
- JANE YIDAN ZHU, Principal investigator, Haven of Hope Hospital, Hong Kong
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06209944
- Sponsor's protocol ID
- CCI and outcome of CPR
- Status last verified
- Jan 2024
- First submitted
- 1 Oct 2023
- Last updated
- 18 Jan 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Jan 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Retrospective Review on Charlson Comorbidity Index (CCI) as a Predictor of Return-of-spontaneous-circulation and Survival-to-discharge of Geriatric In-hospital Cardiopulmonary Resuscitation (CPR) in a Regional Acute Hospital in Hong Kong
- ClinicalTrials.gov ID
- NCT06209944
- Acronym / sponsor ID
- CCI and outcome of CPR
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 394 participants (actual)
- Lead sponsor
- Jane Yidan ZhuUniversity, hospital or other
- Study start
- 2 May 2019 (actual)
- Primary completion
- 31 Dec 2019 (actual)
- Study completion
- 31 Dec 2019 (actual)
- First posted
- 18 Jan 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:
- Whether age would affect outcome
- Whether Charlson Comorbidity Index would affect outcome
- Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival.
Researchers would compare the patients who deceased with the patients who survived.
Detailed description
The goal of this review was to investigate the impact of age, existing medical conditions. and other factors before cardiac arrest in predicting outcome of in-hospital cardiopulmonary resuscitation (CPR) of older persons.
It was conducted on all patients aged ≥ 65, who underwent CPR in acute medical and geriatric wards (excluding Intensive Care Unit) in United Christian Hospital from January 2017 to December 2018.
Study design
- Observational model
- Case only
- Time perspective
- Retrospective
Who may qualify
- Ages
- 65 to 101 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (a regional acute hospital with total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
Key inclusion criteria (2 listed)
- All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
- In patients with multiple resuscitation events, only the first in-hospital CPR was included.
Key exclusion criteria (4 listed)
- Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
- Patients younger than 65 years old
- Out-of-hospital CPR in the index admission
- CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cardiopulmonary resuscitationcardiac compression, endotracheal intubation, defibrillation, and use of cardiovascular medications, to restore circulation in patients with cardiac arrest | Procedure or surgery | – |
Primary outcome
sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.
Time frame: 2017 - 2018
Sustained ROSC is defined as documented return of adequate circulation in the absence of ongoing chest compressions, and the duration should be of 20 minutes or above
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jan 2024.
- Individual participant dataSharing planned: No
Related trials for Comorbidities and Coexisting Conditions
Active, not recruiting
Streamlined Geriatric and Oncological Evaluation Based On IC Technology
Breast Cancer, Comorbidities and Coexisting Conditions
RecruitingPhase 2/3
Evaluating Smoking Cessation Interventions for PWH in South Africa
Smoking Cessation, HIV
RecruitingObservational study
Frailty in Outpatient Digestive Endoscopy
Frailty, Comorbidities and Coexisting Conditions
Recruiting
eCardiacRehab - a Hybrid Patient-Centered eHealth Programme
Comorbidities and Coexisting Conditions, Ethics
Active, not recruiting
Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity
Asthma Bronchiale, Breast Neoplasms
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
JANE YIDAN ZHU principal investigator
Haven of Hope Hospital, Hong Kong
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Comorbidities and Coexisting Conditions and Cardiopulmonary Resuscitation, run by Jane Yidan Zhu at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Jan 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year. (time frame: 2017 - 2018). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jan 2024.