TrustNCT06176092
UCF Deciding Brains
An observational study of Trust, run by University of Central Florida at 1 site in United States.
Trial summary
The purpose of this research study is to understand how people make trust-related decisions in healthy aging. Participants will be asked to complete one study session on the University of Central Florida (UCF) campus. Read more about this study
- Who is it for?
- Ages 20 years and olderHealthy volunteers can take part
- Conditions the study is for
- Trust
- How many people
- 400 participants
- Where
- 1 siteUnited States
- Study dates
- 21 Sep 2023to Jun 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: This study will target any healthy participants who are either between the ages of 20-39 or 60 and older.
Who may be able to join
- Younger adults only: Age 20-39 years old
- Older adults only: Age 60 years old and older
- Fluent English speaker
- At least 8th grade education
- On a stable regimen of medications
- Able to provide verbal and written informed consent
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- Normal cognitive function
- Older adults only: The above will be assessed/confirmed via cognitive screening assessments
- Telephone Interview for Cognitive Status (TICS-M; see "Telephone Interview for Cognitive Status" in Local Site Documents)
Who cannot join
- Pregnant
- Presence of:
- Schizophrenia Spectrum or Other Psychotic Disorders
- Bipolar and Related Disorders
- Depressive Disorders
- Anxiety Disorders
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- Trauma- and Stressor-Related Disorders
- Substance-Related and Addictive Disorders
- Current anticonvulsant, neuroleptic, or sedative use
- Uncorrected visual and hearing impairments
- Neurologic condition or event affecting the brain in the last 12 months (e.g., stroke, epilepsy, traumatic brain injury with >30-minute loss of consciousness)
- History of brain surgery including tumor resection, deep brain resection, pallidotomy, and thalamotomy
- Unstable medical illness (e.g., metastatic cancer)
- Significant cardiovascular condition or event in the last 12 months (e.g., major heart attack, heart bypass surgery
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Central Florida
Orlando, Florida, 32827
Amoy Fraser, PhD, CCRP, PMP, 4072668742, Amoy.Fraser@ucf.edu
About this study
The purpose of this research study is to understand how people make trust-related decisions in healthy aging.
Participants will be asked to complete one study session on the University of Central Florida (UCF) campus. The study session will be conducted in a private testing room and include a series of computerized cognitive tasks and learning games, as well as surveys of your beliefs, preferences, and past experiences.
The study will take a total of approximately 3.5 hours to completed. You will be allowed to take breaks during the session as needed. If you begin the study but do not complete the session, you will receive credit commensurate with your participation.
Read the detailed description
Much of human interaction is based on trust. Optimal trust-related decision making and avoiding exploitation require the ability to learn about the trustworthiness of social partners across multiple interactions, but the role that learning plays in determining age deficits in trust decisions is currently unknown. To address this gap, this project will characterize basic cognitive processes in learning to trust and distrust in healthy aging.
The present study will examine age differences in learning to trust using laboratory tasks and surveys. The investigators hypothesize that social cues of trustworthiness will bias learning more in older adults (social cue bias, H1). Further, we predict that social cues of trustworthiness will interact with weighting of negative (loss aversion bias, H2) and recent (recency bias; H3) outcomes, and that these biases are exacerbated in older adults compared with younger adults (H4).
Young adult participants (age 20-39 years) will be recruited through the SONA pool. Older adult participants (age 60 and older) will be recruited from the University of Central Florida (UCF) Learning and Longevity Research Network (LLRN) registry and will be contacted by lab personnel via emails. Emails retrieved from the LLRN registry are provided by older-aged participants who wished to be contacted for research. Older adults will be screened to exclude those with cognitive impairment before being invited to participate. Those who meet criteria for inclusion in the study, will be scheduled for a study session in the lab.
- Conditions
- Trust
- Keywords
- Healthy, Psychology
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Younger Adults (ages 20-39) | The study will examine age differences in learning to trust using laboratory tasks and surveys. | |
| Older Adults (60 and older) | The study will examine age differences in learning to trust using laboratory tasks and surveys. |
What is being measured
The primary outcome is the main question the study is designed to answer.
NIH Cognitive Toolbox
The NIH Toolbox which includes cognitive tasks to measure: Cognitive Function Composite Score, Fluid Cognition Composite Score, and Crystallized Cognition Composite Score
Measured: 1 year
social Iowa Gambling Task (sIGT)
To investigate how older adults learn to trust others over multiple interactions, we developed the social Iowa Gambling Task (sIGT); modeled after the original Iowa Gambling Task.
Measured: 1 year
Florida-Arizona Gambling Task (FLAG)
To examine choices between a sure offer and a draw from a deck of cards.
Measured: 1 year
Phishing Email Suspicion Test (PEST)
This measures an individual's ability to detect phishing emails and has ecological validity pertaining to real-life internet fraud susceptibility.
Measured: 1 year
Detection of Liars and Truth Tellers (LIE Task)
Participants will view brief videos of real crime suspects, who were either lying (liars) or telling the truth (truth tellers) about their involvement in the disappearance of a relative
Measured: 1 year
Charity Task
This charity task assesses factors that can potentially influence charitable giving to organizations among younger and older adults, including familiarity, transparency, and personal importance.
Measured: 1 year
Survey battery
The following surveys will that assess individual differences in CISDA factors and other potential exploitation risk predictors will be administered:
(i) Theory of mind: (ii) Memory systems (iii) Socio-emotional processing (iv) Pain measures (v) Phishing vulnerability (vi) Demographics
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Dec 2023
- Study start21 Sep 2023
- Primary completionJun 2025 (estimated)
- Study completionJun 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for TrustStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 400 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Central Florida
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Nichole Lighthall, PhD, Principal investigator, University of Central Florida
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06176092
- Sponsor's protocol ID
- STUDY00005797
- Status last verified
- Mar 2025
- First submitted
- 10 Dec 2023
- Last updated
- 27 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- UCF Deciding Brains
- ClinicalTrials.gov ID
- NCT06176092
- Acronym / sponsor ID
- STUDY00005797
- Conditions
- Trust
- Keywords
- Healthy, Psychology
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 400 participants (estimated)
- Lead sponsor
- University of Central FloridaUniversity, hospital or other
- Study start
- 21 Sep 2023 (actual)
- Primary completion
- Jun 2025 (estimated)
- Study completion
- Jun 2029 (estimated)
- First posted
- 19 Dec 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this research study is to understand how people make trust-related decisions in healthy aging.
Participants will be asked to complete one study session on the University of Central Florida (UCF) campus. The study session will be conducted in a private testing room and include a series of computerized cognitive tasks and learning games, as well as surveys of your beliefs, preferences, and past experiences.
The study will take a total of approximately 3.5 hours to completed. You will be allowed to take breaks during the session as needed. If you begin the study but do not complete the session, you will receive credit commensurate with your participation.
Detailed description
Much of human interaction is based on trust. Optimal trust-related decision making and avoiding exploitation require the ability to learn about the trustworthiness of social partners across multiple interactions, but the role that learning plays in determining age deficits in trust decisions is currently unknown. To address this gap, this project will characterize basic cognitive processes in learning to trust and distrust in healthy aging.
The present study will examine age differences in learning to trust using laboratory tasks and surveys. The investigators hypothesize that social cues of trustworthiness will bias learning more in older adults (social cue bias, H1). Further, we predict that social cues of trustworthiness will interact with weighting of negative (loss aversion bias, H2) and recent (recency bias; H3) outcomes, and that these biases are exacerbated in older adults compared with younger adults (H4).
Young adult participants (age 20-39 years) will be recruited through the SONA pool. Older adult participants (age 60 and older) will be recruited from the University of Central Florida (UCF) Learning and Longevity Research Network (LLRN) registry and will be contacted by lab personnel via emails. Emails retrieved from the LLRN registry are provided by older-aged participants who wished to be contacted for research. Older adults will be screened to exclude those with cognitive impairment before being invited to participate. Those who meet criteria for inclusion in the study, will be scheduled for a study session in the lab.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Younger Adults (ages 20-39) | – | –The study will examine age differences in learning to trust using laboratory tasks and surveys. |
| Older Adults (60 and older) | – | –The study will examine age differences in learning to trust using laboratory tasks and surveys. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- This study will target any healthy participants who are either between the ages of 20-39 or 60 and older.
Key inclusion criteria (9 listed)
- Younger adults only: Age 20-39 years old
- Older adults only: Age 60 years old and older
- Fluent English speaker
- At least 8th grade education
- On a stable regimen of medications
Key exclusion criteria (14 listed)
- Pregnant
- Presence of:
- Current anticonvulsant, neuroleptic, or sedative use
- Uncorrected visual and hearing impairments
- Neurologic condition or event affecting the brain in the last 12 months (e.g., stroke, epilepsy, traumatic brain injury with >30-minute loss of consciousness)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
NIH Cognitive Toolbox
Time frame: 1 year
The NIH Toolbox which includes cognitive tasks to measure: Cognitive Function Composite Score, Fluid Cognition Composite Score, and Crystallized Cognition Composite Score
social Iowa Gambling Task (sIGT)
Time frame: 1 year
To investigate how older adults learn to trust others over multiple interactions, we developed the social Iowa Gambling Task (sIGT); modeled after the original Iowa Gambling Task.
Florida-Arizona Gambling Task (FLAG)
Time frame: 1 year
To examine choices between a sure offer and a draw from a deck of cards.
Phishing Email Suspicion Test (PEST)
Time frame: 1 year
This measures an individual's ability to detect phishing emails and has ecological validity pertaining to real-life internet fraud susceptibility.
Detection of Liars and Truth Tellers (LIE Task)
Time frame: 1 year
Participants will view brief videos of real crime suspects, who were either lying (liars) or telling the truth (truth tellers) about their involvement in the disappearance of a relative
Charity Task
Time frame: 1 year
This charity task assesses factors that can potentially influence charitable giving to organizations among younger and older adults, including familiarity, transparency, and personal importance.
Survey battery
Time frame: 1 year
The following surveys will that assess individual differences in CISDA factors and other potential exploitation risk predictors will be administered: (i) Theory of mind: (ii) Memory systems (iii) Socio-emotional processing (iv) Pain measures (v) Phishing vulnerability (vi) Demographics
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Mar 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nichole Lighthall, PhD principal investigator
University of Central Florida
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Trust, run by University of Central Florida at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 14 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 27 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Amoy Fraser, PhD (4072668742, amoy.fraser@ucf.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NIH Cognitive Toolbox (time frame: 1 year). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Mar 2025.