Motor ActivityNCT06016660

Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation

A study testing Physiotherapy in people with Motor Activity, run by Gazi University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Who is it for?: Any ageHealthy volunteers can take part
Conditions the study is for: Motor Activity
What is being tested?: Physiotherapy
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 21 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 1 May 2022to 1 Jan 2023
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages Any age
All sexes
Healthy volunteers accepted
Child, Adult, Older adult

Who may be able to join

After providing detailed information about the study, individuals who had agreed to participate in the research were included in the study.

Who cannot join

Individuals with any central or peripheral nervous system disease/injury affecting the upper extremity,
Individuals with a history of orthopedic injury that could impact the study,
Individuals with a history of neuromuscular disease, congenital anomalies, skin infections, or cognitive impairments,
Individuals with a history of systemic or metabolic diseases that could potentially affect the study,
Individuals with a body mass index (BMI) above 30 kg/m2.

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Barış SEVEN
Izmir, Çiğli

Other trials in Turkey (Türkiye)

About this study

The aim of our study is to investigate the effects of single-session resistance exercise, neuromuscular electrical stimulation, and transcutaneous electrical stimulation on the level of muscle activation and their superiority over each other on both the ipsilateral and contralateral sides. Our randomized controlled crossover study included 21 participants (13 female, 8 male, age; 27.7±4). Transcutaneous electrical stimulation was used for sensory input. A single-session application was performed only to the right extremities of all participants, and the acute effects on muscle activation on both the ipsilateral and contralateral sides were evaluated. Muscle activation was evaluated with superficial EMG. SPSS® Statistics V22.0 software was used for statistical analysis. As a result of the statistical analysis, a significant increase in activation was found only in the sensory input application group on the ipsilateral side flexor carpi radialis (FCR) (p=0.001), flexor carpi ulnaris (FCU) (p<0.001), flexor digitorum superficialis (FDS) (p=0.023) and flexor digitorum profundus (FDP) (p=0.003) muscles. On the contralateral side, there was an increase in activation in all muscles (FCR; p<0.001, FCU; p=0.033, FDS; p=0.017 and FDP; p=0.001) in the resistant exercise group. In addition, there was a significant increase in the activation of certain muscles on the contralateral side in the NMES application group (FCR (p=0.049) and FDP (p=0.016) muscles) and the sensory input application group (FDP (p=0.004) and FDS (p=0.043) muscles). In situations where movement is contraindicated, ipsilateral sensory input can increase the level of muscle activation through both cortical and peripheral neural mechanisms.In addition, resistance exercise to be performed on the contralateral side can be an effective application to increase muscle activation on the ipsilateral side.

Conditions: Motor Activity
Being tested: Physiotherapy
Medical subject headings: Motor Activity

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

PhysiotherapyOther
Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

Study groups in NCT06016660
Study group	Role	What they receive
Resistance exercise	Experimental	Resistance exercise Receives: Other: Physiotherapy
Neuromuscular electrical stimulation	Experimental	Neuromuscular electrical stimulation Receives: Other: Physiotherapy
Transcutaneous electrical stimulation	Experimental	Transcutaneous electrical stimulation Receives: Other: Physiotherapy
Control	No intervention	No intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

Superficial electromyography
Muscle activation measurement
Measured: through study completion, an average of 1 year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 May 20221 Jan 2023

First posted30 Aug 2023
Study start1 May 2022
Primary completion1 Oct 2022
Study completion1 Jan 2023

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Motor ActivityStudies of the same condition, open and under way.
More trials run by Gazi UniversityThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Crossover
Masking: None (open label)
Enrolment: 21 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT06016660
Sponsor's protocol ID: EMGHealthy
Status last verified: Aug 2023
First submitted: 7 Jun 2023
Last updated: 30 Aug 2023
Results posted: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Motor Activity trials

Study at a glance

From the registry record, last updated by the sponsor on 30 Aug 2023. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation
ClinicalTrials.gov ID: NCT06016660
Acronym / sponsor ID: EMGHealthy
Conditions: Motor Activity
Study type: Interventional
Recruitment status: Completed
Enrolment: 21 participants (actual)
Lead sponsor: Gazi UniversityUniversity, hospital or other
Study start: 1 May 2022 (actual)
Primary completion: 1 Oct 2022 (actual)
Study completion: 1 Jan 2023 (actual)
First posted: 30 Aug 2023 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Crossover
Masking: None (open label)
Number of arms: 4

Arm	Type	Receives
Resistance exercise	Experimental	Other: PhysiotherapyResistance exercise
Neuromuscular electrical stimulation	Experimental	Other: PhysiotherapyNeuromuscular electrical stimulation
Transcutaneous electrical stimulation	Experimental	Other: PhysiotherapyTranscutaneous electrical stimulation
Control	No intervention	–No intervention

Who may qualify

Sex: All
Healthy volunteers: Accepted
Age groups: Child, Adult, Older adult

Key inclusion criteria (1 listed)

After providing detailed information about the study, individuals who had agreed to participate in the research were included in the study.

Key exclusion criteria (5 listed)

Individuals with any central or peripheral nervous system disease/injury affecting the upper extremity,
Individuals with a history of orthopedic injury that could impact the study,
Individuals with a history of neuromuscular disease, congenital anomalies, skin infections, or cognitive impairments,
Individuals with a history of systemic or metabolic diseases that could potentially affect the study,
Individuals with a body mass index (BMI) above 30 kg/m2.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
PhysiotherapyResistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation	Other	Neuromuscular electrical stimulation, Resistance exercise, Transcutaneous electrical stimulation

Primary outcome

Superficial electromyography
Time frame: through study completion, an average of 1 year
Muscle activation measurement

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 30 Aug 2023.
Individual participant dataSharing planned: No

Related trials for Motor Activity

Recruiting
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Physical Activity, Body Image
Not yet recruiting
Feasibility of a Robot-Guided Active Play Intervention for Children With Cerebral Palsy
Cerebral Palsy
Enrolling by invitation
Online Exercise Program for Transplant Patients: A Pilot Study
Kidney Transplantation, Physical Function
Recruiting
Effect of a Brief Daily Digital Meditation on Well-Being in US Young Adults (BEGIN II)
Mental Health and General Well-being
Active, not recruitingPhase 4
Effects of Sequential Therapy With Mexidol® (Intravenous) and Mexidol® FORTE 250 (Oral) on Functional Brain Activity Assessed by Functional Magnetic Resonance Imaging and Biochemical Parameters in Patients With Chronic Cerebral Ischemia: A Comparison of Patients With and Without Metabolic Disorders
Metabolic Abnormalities, Obesity & Overweight

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

The record lists no contact. Use the official record to reach the sponsor.

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Physiotherapy in people with Motor Activity, run by Gazi University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 30 Aug 2023. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Superficial electromyography (time frame: through study completion, an average of 1 year). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06016660.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Aug 2023.