Chronic PainERASEDNCT05991440
Examining Racial and Socioeconomic Differences in Chronic Low Back Pain
An observational study of Chronic Pain, run by Washington University School of Medicine at 1 site in United States.
Trial summary
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP). Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Chronic Pain
- How many people
- 240 participants
- Where
- 1 siteUnited States
- Study dates
- 22 Apr 2024to 31 Dec 2028
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: For this study we will incorporate a combination of clinic-based and community-based participant recruitment. Participants will be recruited from the Pain Treatment Clinics at the Wash U Pain Center and VUMC, as well as the surrounding communities in St. Louis and Nashville, respectively.
Who may be able to join
- Non-specific cLBP that has persisted for at least 3 months and has resulted in pain on at least half the days in the past 6 months.
- Age 18 - 85; the lower end of this age range was chosen to capture the growing prevalence of young adults with cLBP, and participants over 85 years are increasingly likely to meet one or more exclusion criteria.
- Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian.
Who cannot join
- Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma.
- Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia).
- Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain.
- A history of clinically significant surgery to the low back within the past year.
- Uncontrolled hypertension (i.e. SBP/DBP of > 150/95), cardiovascular or peripheral arterial disease.
- Poorly controlled diabetes (HbA1c > 8%).
Show all 9Show fewer
- Neurological disease (e.g. Parkinson's, multiple sclerosis, epilepsy).
- Serious psychiatric disorder requiring hospitalization within the past 12 months or characterized by active suicidal ideation.
- Diminished cognitive function that would interfere with understanding of study procedures.
Trial locations and contacts
1 site in 1 country.
United States1 site
Washington University School of Medicine
St Louis, Missouri, 63110
About this study
Official title: Racial and Socioeconomic Differences in Chronic Low Back Pain
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
- Conditions
- Chronic Pain
- Keywords
- lower back pain, Race, Socioeconomic
- Medical subject headings
- Chronic Pain, Low Back Pain
What is being measured
The primary outcome is the main question the study is designed to answer.
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.
Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.
Measured: two years
To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.
Quantitative sensory testing equipment and biological markers assayed via blood samples.
Measured: two years
To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.
Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.
Measured: two years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2023
- Study start22 Apr 2024
- Primary completion31 Dec 2027 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic PainStudies of the same condition, open and under way.
- More trials run by Washington University School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 240 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Washington University School of Medicine
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Minority Health and Health Disparities (NIMHD)
- Responsible party
- Principal investigator, Burel Goodin, Washington University School of Medicine
- Investigators
- Burel Goodin, PhD, Principal investigator, Washington University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05991440
- Sponsor's protocol ID
- 202306132
- Other IDs
- R01MD017565
- Acronym
- ERASED
- Status last verified
- Oct 2026
- First submitted
- 31 Jul 2023
- Last updated
- 16 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No