CancerNCT05988892
A Study of Physical Activity in Cancer Survivors
A study testing Physical Activity in people with Cancer and Hematopoietic and Lymphatic System Neoplasm, run by Mayo Clinic at 4 sites in United States.
Trial summary
The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Cancer, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
- What is being tested?
- Physical Activity
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 4 sitesUnited States
- Study dates
- 29 Jun 2023to 23 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI), Southwest Wisconsin (SWWI), Southeast Minnesota (SEMN), or Southwest Minnesota (SWMN)
- Any stage cancer
- Age >= 18 years residing at a rural address (as defined by Rural America, census.gov Urban Areas 2020 metric)
- Age ≥ 18 years residing at a rural address (as defined by Rural America, census.gov)
- Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible.
- Ownership of a computer/tablet/smartphone with internet access.
Show all 10Show fewer
- Willingness to create a google account and maintain the account for use of the Fitbit
- Willingness and ability to attend study visits.
- Must be able to complete semi-tandem (10 seconds), side-by-side tandem [10 seconds and short physical performance batters(SPPB)] Score of 6 or greater to qualify for virtual exercise.
- Must be ambulatory without the use of assisted device(s).
Who cannot join
- Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment
- Are already performing >150 minutes/week of moderate activity or 75 min/week of vigorous physical activity
- Cancer-free for greater than 5 years
- Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.
- Squamous cell or basal cell skin cancers (melanoma still eligible)
- Stage 0/in situ vulvar/cervical cancers
Trial locations and contacts
4 sites in 1 country.
United States4 sites
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, 56007
Mayo Clinic Health System-Eau Claire Clinic
Eau Claire, Wisconsin, 54701
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin, 54601
Mayo Clinic Health System-Mankato
Mankato, Minnesota, 56001
About this study
Official title: Improving Physical Activity in Rural Cancer Survivors
The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.
- Being tested
- Physical Activity
- Keywords
- Rural, Physical Activity
- Medical subject headings
- Neoplasms, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Physical ActivityBehavioural
Use Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.
| Study group | Role | What they receive |
|---|---|---|
| Community Oncology patients entering cancer survivorship | Experimental | Patients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive bi-weekly phone calls/emails over 12 weeks. Patents also wear a Fitbit on study. Receives: Behavioral: Physical Activity |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in physical functioning using Short Physical Performance Battery
Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention.
Measured: Baseline; 12 weeks
Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS)
QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention.
Measured: Baseline; 12 weeks
Change in satisfaction using a 5-point Likert scale
Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program.
Measured: Baseline; 12 weeks
Rate of adherence to program based on participation in virtual exercise sessions
Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention.
Measured: Baseline; 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Aug 2023
- Study start29 Jun 2023
- Primary completion23 Apr 2025
- Study completion23 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CancerStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Kaye T. Sturz, APRN, CNP, Principal investigator, Mayo Clinic Health System in Eau Claire
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05988892
- Sponsor's protocol ID
- 23-001462
- Other IDs
- NCI-2023-05387
- Status last verified
- Oct 2025
- First submitted
- 26 Jul 2023
- Last updated
- 23 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Improving Physical Activity in Rural Cancer Survivors
- ClinicalTrials.gov ID
- NCT05988892
- Acronym / sponsor ID
- 23-001462
- Keywords
- Rural, Physical Activity
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- 29 Jun 2023 (actual)
- Primary completion
- 23 Apr 2025 (actual)
- Study completion
- 23 Apr 2025 (actual)
- First posted
- 14 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine if increasing physical activity (PA) will increase physical functioning, as measured by cardiovascular endurance, muscular strength, and balance in underserved adult cancer survivors > 60 years of age and/or those of any age residing at a rural address. Also, to determine if increasing PA will increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address.
Study design
- Primary purpose
- Health services research
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Community Oncology patients entering cancer survivorship | Experimental | Behavioral: Physical ActivityPatients participate in a virtual cancer rehabilitation program with weekly virtual visits by a cancer exercise specialist who provides a personalized synchronous exercise plan and receive bi-weekly phone calls/emails over 12 weeks. Patents also wear a Fitbit on study. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (10 listed)
- Adult, cancer survivors (no active disease) at Mayo Clinic Health System (MCHS) in Northwest Wisconsin (NWWI), Southwest Wisconsin (SWWI), Southeast Minnesota (SEMN), or Southwest Minnesota (SWMN)
- Any stage cancer
- Age >= 18 years residing at a rural address (as defined by Rural America, census.gov Urban Areas 2020 metric)
- Age ≥ 18 years residing at a rural address (as defined by Rural America, census.gov)
- Completed active treatment of surgery, (neo)adjuvant chemotherapy, and/or (neo) adjuvant radiation. Patients receiving adjuvant endocrine therapy, targeted therapy, or immunotherapy therapies are eligible.
Key exclusion criteria (6 listed)
- Receiving surgery, (neo)adjuvant chemotherapy, (neo) adjuvant radiation, palliative treatment
- Are already performing >150 minutes/week of moderate activity or 75 min/week of vigorous physical activity
- Cancer-free for greater than 5 years
- Unable to complete weekly interventions/exercise due to traveling or unable to be active for more than 7 consecutive days.
- Squamous cell or basal cell skin cancers (melanoma still eligible)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Physical ActivityUse Exercise to increase physical activity (PA), as measured by cardiovascular endurance, muscular strength, and balance in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address and to increase quality of life (QOL), as measured by physical functioning and fatigue, in underserved cancer survivors >60 years of age and/or those of any age residing at a rural address. | Behavioural | Community Oncology patients entering cancer survivorship |
Primary outcome
Change in physical functioning using Short Physical Performance Battery
Time frame: Baseline; 12 weeks
Change in physical functioning based on improvement in endurance, strength, and balance assessed using Short Physical Performance Battery (SPPB) pre- and post-12-week exercise intervention.
Change in Quality of Life (QOL) using Patient-Reported Outcomes Measurement Information System (PROMIS)
Time frame: Baseline; 12 weeks
QOL evaluated based on physical functioning and fatigue, assessed using Patient-Reported Outcomes Measurement Information System (PROMIS) pre- and post-12-week exercise intervention.
Change in satisfaction using a 5-point Likert scale
Time frame: Baseline; 12 weeks
Satisfaction assessed using a 5-point Likert scale following 12-week exercise intervention and participant-reporting likelihood of recommending program.
Rate of adherence to program based on participation in virtual exercise sessions
Time frame: Baseline; 12 weeks
Adherence evaluated based on participation in virtual exercise sessions during 12-week exercise intervention.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Mar 2026.
- Mayo Clinic Clinical TrialsLink provided by the sponsor.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Kaye T. Sturz, APRN, CNP principal investigator
Mayo Clinic Health System in Eau Claire
4 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Physical Activity in people with Cancer and Hematopoietic and Lymphatic System Neoplasm, run by Mayo Clinic at 4 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 10 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 4 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in physical functioning using Short Physical Performance Battery (time frame: Baseline; 12 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Mar 2026.