Psychosis Associated With Alzheimer's DiseasePhase 3NCT05980949

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

A Phase 3 study testing KarXT in people with Psychosis Associated With Alzheimer's Disease, run by Karuna Therapeutics, Inc., a Bristol Myers Squibb company at 432 sites in 31 countries.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts

Official record

Search all trials

Trial summary

Who is it for?: Ages 55 to 90 years
Conditions the study is for: Psychosis Associated With Alzheimer's Disease
What is being tested?: KarXT
Type of treatment: Pill or oral medicine
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 1,000 participants
Where: 432 sitesin 31 countries
Study dates: 11 Jul 2023to 7 Sep 2027
Phase: Phase 3

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 55 to 90 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Must have completed study KAR-031 (CN012-0026), KAR-032(CN012-0027), or CN012-0056. This Inclusion criterion is not applicable for Protocol Amendment 07 or later versions.
Can understand the nature of the study and protocol requirements and provide a signed informed consent (IC) form before any study assessments are performed. If the subject is deemed not competent to provide IC, both the following requirements for consent must be met:
The subject's legally acceptable representative (LAR) must provide IC
The subject must provide informed assent
Must have stable living environment. At entry into this study, or any time during the study, if a subject needs to relocate from home, a residential assisted-living facility, or other stable location to a nursing home facility, the Sponsor/Medical Monitor must approve the subject's participation in the study.

Who cannot join

Significant or severe medical conditions that, in the opinion of the Investigator, could jeopardize the safety of the subject, ability to complete or comply with the study procedures or validity of the study results.
Clinically significant abnormalities, including any finding(s) from the ECG, laboratory tests, physical examination, or vital signs, at the EOT visit of Study KAR-031 (Visit 19), Study KAR-032 (Visit 12), Study CN012-0056 (Visit 12) that the Investigator, in consultation with the Medical Monitor, are considered to jeopardize the safety of the subject.
Subjects participating in another investigational drug or device study or planning on participating in another clinical study during the duration of KAR-033.
Other protocol-defined Inclusion/Exclusion criteria apply.

Trial locations and contacts

432 sites in 31 countries. Contact the study team or a site near you to ask about taking part.

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com contact

855-907-3286

Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #. contact

Country

City, postcode or hospital

Sites recruiting now only

432 sites in 31 countries

United States148 sites, 87 recruiting

Advanced Research Center, Inc.
Anaheim, California, 92805-5854
Steven Macina, Site 1104, 714-999-6688
Recruiting
Local Institution - 1241
Arlington, Virginia, 22205
Site 1241
Not yet recruiting
Agile Clinical Research Trials, LLC
Atlanta, Georgia, 30328-5532
Vasundhara Cheekati, Site 1206, 404-382-8660
Recruiting
Local Institution - 1225
Atlantis, Florida, 33462
Withdrawn
Local Institution - 1223
Belmont, Massachusetts, 02478-1064
Site 1223
Not yet recruiting
Local Institution - 1037
Berwyn, Illinois, 60402-2173
Withdrawn
Local Institution - 1-146Y4PVY
Bloomfield Township, Michigan, 48302-1909
Withdrawn
Local Institution - 1248
Bloomfield Township, Michigan, 48302-1909
Site 1248
Not yet recruiting
Local Institution - 1011
Boca Raton, Florida, 33487-2768
Withdrawn
Envision Trials LLC
Bonita Springs, Florida, 34134
Daniel Mandri, Site 1020, 305-819-2909
Recruiting
Local Institution - 1245
Boston, Massachusetts, 02111-1552
Site 1245
Not yet recruiting
Local Institution - 1015
Bradenton, Florida, 34209-4687
Withdrawn
Local Institution - 1-13H98LK9
Chandler, Arizona, 85224-6231
Withdrawn
Local Institution - 1227
Chandler, Arizona, 85224
Withdrawn
Local Institution - 1116
Chandler, Arizona, 85286
Withdrawn
Local Institution - 1035
Charleston, South Carolina, 29425-8900
Withdrawn
Local Institution - 1-141NO1DG
Chino, California, 91710
Site 1-141NO1DG
Not yet recruiting
Local Institution - 1244
Chino, California, 91710
Site 1244
Not yet recruiting
Local Institution - 1156
Clermont, Florida, 34711-5190
Withdrawn
K2 Medical Research - Winter Garden
Clermont, Florida, 34711-5933
Christopher Galloway, Site 1048, 321-500-5252
Recruiting
Local Institution - 1014
Colorado Springs, Colorado, 80907-5302
Withdrawn
Local Institution - 1201
Columbus, Ohio, 43210
Site 1201
Not yet recruiting
Local Institution - 1001
Costa Mesa, California, 92626
Withdrawn
JY Research Institute Inc
Cutler Bay, Florida, 33189-1230
Suez Oramas Mingo, Site 1138, 305-424-8696
Recruiting
Horizon Clinical Research: Gill Neuroscience
Cypress, Texas, 77429-6070
Harpaul Gill, Site 1106, 949-491-0710
Recruiting
Local Institution - 1122
Dayton, Ohio, 45459-4248
Withdrawn
Arrow Clinical Trials
Daytona Beach, Florida, 32117-5532
David Billmeier, Site 1023, 386-278-8000
Recruiting
Local Institution - 1161
Decatur, Georgia, 30030
Withdrawn
Local Institution - 1224
Deerfield Beach, Florida, 33442
Withdrawn
Local Institution - 1162
Delray Beach, Florida, 33445-2581
Withdrawn
Local Institution - 1121
DeSoto, Texas, 75115-2043
Site 1121
Not yet recruiting
Integrity Clinical Research LLC - 21st Street
Doral, Florida, 33122-1620
Lucinda Cuervo-Ramos, Site 1164, 305-888-0410
Recruiting
Betancourt Research Services
Doral, Florida, 33172-2638
Beatriz Triana, Site 1045, 786-741-2287
Recruiting
Local Institution - 1208
El Paso, Texas, 79912-1743
Site 1208
Not yet recruiting
Local Institution - 1148
Elgin, Illinois, 60123-9215
Withdrawn
Local Institution - 1151
Encino, California, 91316
Withdrawn
Local Institution - 1033
Encino, California, 91436-2201
Withdrawn
University of Connecticut Health Center
Farmington, Connecticut, 06030
Neha Jain, Site 1222, 860-790-7354
Recruiting
Local Institution - 1022
Flower Mound, Texas, 75028-2011
Withdrawn
Precise Research Centers
Flowood, Mississippi, 39232
Joseph Kwentus, Site 1132, 601-420-5810
Recruiting
Local Institution - 1165
Fort Myers, Florida, 33912-4302
Withdrawn
Local Institution - 1036
Frisco, Texas, 75034-6262
Withdrawn
Local Institution - 1247
Gilbert, Arizona, 85297
Site 1247
Not yet recruiting
Local Institution - 1221
Greensboro, North Carolina, 27410-3311
Site 1221
Not yet recruiting
Local Institution - 1155
Hialeah, Florida, 33012-3158
Completed
Direct Helpers Research Center
Hialeah, Florida, 33012-3618
Manuel Fernandez, Site 1107, 305-828-3555
Recruiting
New Life Medical Research Center -3750 W 16th Ave
Hialeah, Florida, 33012-4648
Jorge Betancourt, Site 1120, 305-456-7782
Recruiting
Local Institution - 1046
Hialeah, Florida, 33012-5826
Site 1046
Not yet recruiting
Las Mercedes Medical Research - 4440 West 16th Ave
Hialeah, Florida, 33012
Frank Carlos Alvarez Li, Site 1052, 786-334-6675
Recruiting
Local Institution - 1-13JED81K
Hialeah, Florida, 33013
Withdrawn
Local Institution - 1237
Hialeah, Florida, 33013
Withdrawn
Galiz Research
Hialeah, Florida, 33016-1814
Jose Gamez, Site 1140, 305-805-0921
Recruiting
Nexus Clinical Research Center- NRC
Homestead, Florida, 33030
John Cintron, Site 1229
Recruiting
Local Institution - 1145
Homestead, Florida, 33032-8187
Withdrawn
Coral Clinic Research
Homestead, Florida, 33032
Nelson Gonzalez, Site 1049, 786-715-2200
Recruiting
Homestead Associates in Research Inc-30328 Old Dixie Hwy
Homestead, Florida, 33033
Angel Carrasco, Site 1159, 786-422-7374
Recruiting
Local Institution - 1029
Homewood, Alabama, 35209-6809
Withdrawn
Clinical Trial Network - 7080 Southwest Fwy
Houston, Texas, 77074-2085
Djamchid Lotfi, Site 1004, 713-484-6947
Recruiting
Local Institution - 1031
Irvine, California, 92612-1246
Withdrawn
Local Institution - 1254
Kirkland, Washington, 98034-3030
Site 1254
Not yet recruiting
Local Institution - 1142
Lancaster, California, 93534-2839
Withdrawn
Local Institution - 1127
Largo, Florida, 33777-1359
Withdrawn
Local Institution - 1230
Long Beach, California, 90805
Withdrawn
Local Institution - 1117
Los Alamitos, California, 90720-6506
Withdrawn
USC - The Memory and Aging Center (MAC) - Alzheimer Disease Research Center (ADRC)
Los Angeles, California, 90033-5313
Lon Schneider, Site 1226, 323-442-3715
Recruiting
K2 Medical Research - Maitland
Maitland, Florida, 32751-5669
Brandon Lenox, Site 1039, 407-670-5833
Recruiting
Local Institution - 1146
Maitland, Florida, 32751-6138
Withdrawn
Local Institution - 1018
Manhasset, New York, 11030-3816
Withdrawn
Local Institution - 1114
Marrero, Louisiana, 70072-3083
Withdrawn
AMC Research, LLC - Flourish - PPDS
Matthews, North Carolina, 28105-8336
Mohammad Bolouri, Site 1214, 704-364-4000
Recruiting
Premier Clinical Research Institute
Miami, Florida, 33122-1335
Emelina Arocha, Site 1021, 305-445-5994
Recruiting
Angels Clinical Research Institute - Miami
Miami, Florida, 33122-1721
Yanely Pineiro Puebla, Site 1118, 786-218-1733
Recruiting
Local Institution - 1005
Miami, Florida, 33125-3724
Site 1005
Not yet recruiting
CCM Clinical Research Group
Miami, Florida, 33133-4231
Francisco Ricart, Site 1108, 208-346-8900
Recruiting
Wellness Research Center Inc - Miami
Miami, Florida, 33135-1601
Brian Villa, Site 1125, 786-238-7099
Recruiting
A & D Doctor Center
Miami, Florida, 33135-2968
Yordan Orive Gomez, Site 1236, 305-223-2000
Recruiting
Floridian Neuroscience Institute-1901 SW 1 St
Miami, Florida, 33135
Emilio Mantero-Atienza, Site 1115, 305-326-0776
Recruiting
Local Institution - 1010
Miami, Florida, 33137
Withdrawn
MedOne Clinical Research LLC
Miami, Florida, 33145-2455
Thierry Jacquemin, Site 1143, 305-359-7666
Recruiting
Allied Biomedical Research Institute
Miami, Florida, 33155-4630
Michael Pfeffer, Site 1009, 866-879-2507
Recruiting
My Community Research Center, Inc - 7480 Bird Rd
Miami, Florida, 33155-6630
Cesar Guerrero, Site 1113, 786-359-4867
Recruiting
Future Care Solution LLC
Miami, Florida, 33165-3947
Pilar Trueba, Site 1129, 305-888-0410
Recruiting
Reliant Medical Research
Miami, Florida, 33165
Carlos Ramirez Calderon, Site 1150, 786-801-0912
Recruiting
South Florida Research Phase I-IV, Inc. - Miami
Miami, Florida, 33166
Silvia Silva Duluc, Site 1053, 305-669-6166
Recruiting
Novel Clinical Research Center, LLC -7000 SW 97th Ave
Miami, Florida, 33173-1474
Heber Varela, Site 1006, 000-000-0000
Recruiting
Dade Research Center - Miami FL - 7600 SW 87th Ave
Miami, Florida, 33173
Maria Nualart, Site 1111, 305-263-7120
Recruiting
Florida Research Center, Inc.
Miami, Florida, 33174-2950
Sonia Rente, Site 1109, 305-551-8493
Recruiting
Local Institution - 1158
Miami, Florida, 33175
Completed
Serenity Research Center
Miami, Florida, 33176-1451
Sergio Jaramillo, Site 1235, 305-596-2080
Recruiting
IMIC LLC- 9380 SW 150th Str
Miami, Florida, 33176-7947
Leon Ramon, Site 1147, 786-600-7005
Recruiting
New Gen Health
Miami, Florida, 33176
Roberto Hernando, Site 1234, 305-892-1035
Recruiting
Local Institution - 1105
Miami, Florida, 33179-2537
Completed
High Quality Research
Miami, Florida, 33184-1412
Jorge Gonzalez, Site 1157, 305-392-0244
Recruiting
Coral Research Clinic & Coral Diagnostic Center
Miami, Florida, 33186-4643
Jorge Paoli Bruno, Site 1054, 000-000-0000
Recruiting
ONHEALTH Research Center
Miami, Florida, 33186-5882
Maria Rodil, Site 1042, 786-808-0832
Recruiting
New Med Research
Miami Gardens, Florida, 33056-4000
Marta Fernandez, Site 1126, 305-269-7100
Recruiting
San Marcus Research Clinic Inc
Miami Lakes, Florida, 33014-5602
Nancy Navarro Gonzalez, Site 1032
Recruiting
Meridian International Research
Miami Lakes, Florida, 33014-6435
Gonzalo Quesada, Site 1102, 305-705-4494
Recruiting
Local Institution - 1209
Miami Lakes, Florida, 33014
Withdrawn
Ocean Blue Medical Research Center Inc
Miami Springs, Florida, 33166-5260
Antonio Terrelonge, Site 1026, 305-885-8983
Recruiting
Local Institution - 1215
Morehead City, North Carolina, 28557
Site 1215
Not yet recruiting
Local Institution - 1246
Naples, Florida, 34105
Site 1246
Not yet recruiting
Local Institution - 1211
Nashville, Tennessee, 37212-3133
Withdrawn
Local Institution - 1017
New York, New York, 10032
Withdrawn
Local Institution - 1243
North Dartmouth, Massachusetts, 02747-2612
Site 1243
Not yet recruiting
Local Institution - 1212
Ocoee, Florida, 34761-2964
Site 1212
Not yet recruiting
Local Institution - 1101
Okeechobee, Florida, 34972-2568
Withdrawn
Local Institution - 1016
Oklahoma City, Oklahoma, 73112
Site 1016
Not yet recruiting
Local Institution - 1228
Orange, California, 92868-2847
Site 1228
Not yet recruiting
Nova Psychiatry
Orlando, Florida, 32803
David Medina, Site 1242, 407-823-8421
Recruiting
Local Institution - 1136
Orlando, Florida, 32806-1041
Withdrawn
Combined Research Orlando Phase I-IV LLC
Orlando, Florida, 32807-3555
Eric Carbonell, Site 1112, 407-440-4493
Recruiting
Neurology Associates of Ormond Beach
Ormond Beach, Florida, 32174-3101
David McDonald, Site 1204, 386-673-2500
Recruiting
SC3 Research - Pasadena - 960 E. Green St
Pasadena, California, 91106
M. Lorraine Purino, Site 1043, 626-250-2070
Recruiting
Local Institution - 1012
Pensacola, Florida, 32504-8608
Withdrawn
Local Institution - 1217
Phoenix, Arizona, 85006-2528
Site 1217
Not yet recruiting
Local Institution - 1044
Phoenix, Arizona, 85012-2836
Withdrawn
Local Institution - 1238
Plano, Texas, 75093-8225
Withdrawn
Local Institution - 1137
Port Orange, Florida, 32127-2914
Withdrawn
Local Institution - 1205
Port Orange, Florida, 32127
Withdrawn
Local Institution - 1218
Providence, Rhode Island, 02903
Withdrawn
Local Institution - 1213
Rancho Cucamonga, California, 91730
Site 1213
Not yet recruiting
Local Institution - 1139
Rochester Hills, Michigan, 48307-2760
Withdrawn
Local Institution - 1210
San Antonio, Texas, 78229-3901
Site 1210
Not yet recruiting
Local Institution - 1220
Scottsdale, Arizona, 85260-6742
Withdrawn
Local Institution - 1249
Shaker Heights, Ohio, 44122-5288
Site 1249
Not yet recruiting
Local Institution - 1252
Shelby, North Carolina, 28150-3803
Site 1252
Not yet recruiting
Local Institution - 1103
Sherman Oaks, California, 91403-2131
Completed
Local Institution - 1239
Springfield, Massachusetts, 01103
Site 1239
Not yet recruiting
Local Institution - 1255
St Louis, Missouri, 63128
Site 1255
Not yet recruiting
Local Institution - 1008
St. Petersburg, Florida, 33713-8844
Withdrawn
Local Institution - 1134
Stafford, Texas, 77477-3929
Withdrawn
Local Institution - 1013
Stamford, Connecticut, 06905-1206
Withdrawn
Local Institution - 1034
Stony Brook, New York, 11794-0001
Withdrawn
Local Institution - 1133
Sweetwater, Florida, 33182
Completed
Local Institution - 1231
Syracuse, New York, 13203
Withdrawn
Local Institution - 1240
Syracuse, New York, 13210-1718
Site 1240
Not yet recruiting
Local Institution - 1041
Tampa, Florida, 33607-4629
Site 1041
Not yet recruiting
Angels Clinical Research Institute Tampa - Palm Springs - PPDS
Tampa, Florida, 33614-2869
Al Robaina, Site 1123, 813-931-0128
Recruiting
Guardian Angel Research
Tampa, Florida, 33614
Sadaf Bazargan, Site 1124, 813-300-3300
Recruiting
Interventional Psychiatry of Tampa Bay
Tampa, Florida, 33629-5837
Jamie Fernandez, Site 1110, 813-251-1800
Recruiting
Local Institution - 1040
The Villages, Florida, 32159-8955
Withdrawn
Local Institution - 1202
Toms River, New Jersey, 08755
Site 1202
Not yet recruiting
Local Institution - 1232
Toms River, New Jersey, 08755
Withdrawn
Local Institution - 1131
Viera, Florida, 32940
Withdrawn
Sunwise Clinical Research, LLC - Walnut Creek - IVY - PPDS
Walnut Creek, California, 94596
Ira Glick, Site 1007, 925-298-5147
Recruiting
Premiere Research Institute at Palm Beach Neurology, PA
West Palm Beach, Florida, 33407-3209
Paul Winner, Site 1216, 561-845-0500
Recruiting
Five Towns Neurology PC -Woodmere - 923 Broadway
Woodmere, New York, 11598-1739
David Steiner, Site 1025, 516-239-1800
Recruiting

Other trials in United States

China30 sites, 20 recruiting

Local Institution - 7004
Beijing, Beijing Municipality, 100025
Withdrawn
Beijing Anding Hospital Capital Medical University
Beijing, Beijing Municipality, 100088
Qinge Zhang, Site 7005, 8613811591959
Recruiting
Local Institution - 7025
Beijing, Beijing Municipality, 100730
Site 7025
Not yet recruiting
Local Institution - 7027
Changsha, 410008
Site 7027
Not yet recruiting
West China Hospital Sichuan University
Chengdu, Sichuan, 610000
Weihong Kuang, Site 7002, +861898060171
Recruiting
Local Institution - 7015
Chongqing, Chongqing Municipality, 400016
Withdrawn
The Affiliated Brain Hospital of Guangzhou Medical University
Guangzhou, Guangdong, 0
Xiaomei Zhong, Site 7008, 13242847968
Recruiting
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, 510120
Jiehao Zhao, Site 7016, +861355619953
Recruiting
Local Institution - 7009
Guangzhou, Guangdong, 510260
Withdrawn
Local Institution - 7017
Hangzhou, Zhejiang, 310003
Withdrawn
Local Institution - 7010
Hangzhou, Zhejiang, 310013
Withdrawn
Local Institution - 7021
Hangzhou, Zhejiang, 310013
Site 7021
Not yet recruiting
People's Hospital of Zhejiang Province
Hangzhou, Zhejiang, 310014
Zhengluan Liao, Site 7006, 13958024692
Recruiting
Sir Run Run Shaw Hospital Zhejiang University School of Medicine - Qingchun Campus
Hangzhou, Zhejiang, 310016
Wei Chen, Site 7020, +86 138 0573 6335
Recruiting
Local Institution - 7007
Hefei, Anhui, 230022
Withdrawn
Local Institution - 7022
Kunming, 650032
Site 7022
Not yet recruiting
Local Institution - 7012
Nanchang, Jiangxi, 330008
Withdrawn
Local Institution - 7014
Nanjing, Jiangsu, 210009
Withdrawn
The Second Affiliated Hospital of Nanjing Medical University - Main Campus
Nanjing, Jiangsu, 210011
Meijiang Feng, Site 7013, 8618951762651
Recruiting
Local Institution - 7024
Nanjing, Jiangsu, 210029
Site 7024
Not yet recruiting
Local Institution - 7030
Ningbo, Zhejiang, 315016
Site 7030
Not yet recruiting
Shanghai Mental Health Center - PPDS
Shanghai, Shanghai Municipality, 200030
Xia Li, Site 7001, +861377427254
Recruiting
Tongji Hospital of Tongji University
Shanghai, Shanghai Municipality, 200065
Xijin Wang, Site 7028
Recruiting
Local Institution - 7011
Shanghai, Shanghai Municipality, 200080
Withdrawn
Local Institution - 7026
Shanghai, Shanghai Municipality, 200233
Site 7026
Not yet recruiting
Shenzhen Kangning Hospital
Shenzhen, Guangdong, 518118
Yongjun Wang, Site 7003, 8613632587615
Recruiting
Tianjin Anding Hospital(Tianjin mental Health Center)
Tianjin, Tianjin Municipality, 300222
Daliang Sun, Site 7019, +8615122889423
Recruiting
Local Institution - 7018
Wenzhou, Zhejiang, 325000
Withdrawn
Local Institution - 1-14J7PZ32
Xi'an, Shan1xi, 710061
Site 1-14J7PZ32
Not yet recruiting
Local Institution - 7023
Zhenjiang, Jiangsu, 212001
Site 7023
Not yet recruiting

Other trials in China

Japan27 sites, 24 recruiting

Local Institution - 7518
Hachiōji, Tokyo, 193-0811
Site 7518
Not yet recruiting
Local Institution - 7505
Hadano, Kanagawa, 257-0003
Site 7505
Not yet recruiting
Local Institution - 7526
Himeji-Shi, Hyōgo, 672-8044
Site 7526
Not yet recruiting
Funairi nou clinic
Hiroshima, 730-0844
Tomoko Murakami, Site 7516
Recruiting
Local Institution - 1-13H98LYW
Iizuka, Fukuoka, 820-0014
Withdrawn
Local Institution - 7503
Iizuka, Fukuoka, 820-0014
Withdrawn
Koukan Clinic
Kawasaki-Shi, Kanagawa, 210-0852
Yasuhiro Yoshii, Site 7507, 81443668900
Recruiting
Local Institution - 7525
Kōriyama, Fukushima, 963-8052
Site 7525
Not yet recruiting
Local Institution - 1-13H98LTZ
Kumamoto, 861-8002
Site 1-13H98LTZ
Not yet recruiting
Local Institution - 7524
Kumamoto, 861-8002
Site 7524
Not yet recruiting
National Hospital Organization Utano National Hospital
Kyoto, Kyoto, 616-8255
Shinji Sudoh, Site 7511, 81-75-461-5121
Recruiting
Asakayama General Hospital
Sakai, Osaka, 590-0018
Kazue Kamae, Site 7509, 0722294882
Recruiting
Local Institution - 7522
Sapporo, Hokkaido, 006-8555
Site 7522
Not yet recruiting
Local Institution - 7521
Setagaya-Ku, Tokyo, 154-0004
Site 7521
Not yet recruiting
Kurumi Clinic
Setagaya-Ku, Tokyo, 156-0041
Chika Nishimura, Site 7519, 81333277462
Recruiting
Local Institution - 7528
Setagaya-Ku, Tokyo, 156-0057
Site 7528
Not yet recruiting
Local Institution - 7527
tabashi City, Tokyo, 173-0015
Site 7527
Not yet recruiting
Local Institution - 7514
Takamatsu, Kagawa-ken, 760-0065
Site 7514
Not yet recruiting
Local Institution - 7501
Takatsuki, Osaka, 569-1041
Site 7501
Not yet recruiting
Local Institution - 7523
Tatebayashi, 374-0037
Site 7523
Not yet recruiting
Local Institution - 1-13H98LIT
Toride-shi, Ibaraki, 302-0004
Withdrawn
Memory Clinic Toride
Toride-shi, Ibaraki, 302-0004
Youshun Boku, Site 7508, +297796166
Recruiting
Local Institution - 7506
Tsu, Mie-ken, 514-1101
Site 7506
Not yet recruiting
Local Institution - 7520
Yokohama, Kanagawa, 230-0074
Site 7520
Not yet recruiting
Yokohama City Minato Red Cross Hospital
Yokohama, Kanagawa, 2310801
Takuya Ohkubo, Site 7502, 0456286100
Recruiting
Yokohama City University Hospital
Yokohama, Kanagawa, 236-0004
Keiko Ide, Site 7513, 81457872800
Recruiting
Local Institution - 7512
Yoshinogawa, Tokushima, 776-8585
Site 7512
Not yet recruiting

Other trials in Japan

Italy18 sites, 7 recruiting

Azienda Ospedaliero-Universitaria di Modena - Policlinico di Modena
Baggiovara, Modena, 41126
Giovanna Zamboni, Site 2306, +390593962201
Recruiting
IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli
Brescia, Lombardy, 25125
Stefania Orini, Site 2324
Recruiting
Local Institution - 1-13JED83E
Brescia, Lombardy, 25125
Withdrawn
Local Institution - 2308
Florence, Tuscany, 50139
Withdrawn
Local Institution - 2304
Milan, Lombardy, 20122
Withdrawn
Local Institution - 2323
Milan, Lombardy, 20149
Site 2323
Not yet recruiting
Local Institution - 2305
Monza, 20900
Withdrawn
Local Institution - 2302
Pisa, 56126
Withdrawn
Local Institution - 2307
Ponderano (Biella), Piedmont, 13875
Site 2307
Not yet recruiting
Local Institution - 2303
Roma, 00168
Site 2303
Not yet recruiting
Local Institution - 2309
Roma, 00189
Site 2309
Not yet recruiting
Local Institution - 1-13JED80W
Rome, Lazio, 00161
Withdrawn
Local Institution - 2322
Rome, Lazio, 00161
Site 2322
Not yet recruiting
Local Institution - 1-13JED82O
Rome, Lazio, 00166
Withdrawn
Local Institution - 2320
Rome, Lazio, 00166
Withdrawn
Local Institution - 2301
Rome, Lazio, 00179
Withdrawn
Local Institution - 2321
Rome, Roma, 00186
Withdrawn
Local Institution - 1-140JNJT7
Salerno, Campania, 84131
Withdrawn

Other trials in Italy

Poland17 sites, 10 recruiting

Local Institution - 4204
Bydgoszcz, 85-080
Withdrawn
Uniwersyteckie Centrum Kliniczne w Gdansku - Smoluchowskiego 17
Gdansk, Pomeranian Voivodeship, 80-214
Adam Wlodarczyk, Site 4212, 48583493720
Recruiting
Local Institution - 1-13JAX170
Gdansk, Pomeranian Voivodeship, 80-952
Withdrawn
Local Institution - 4215
Iława, Warmian-Masurian Voivodeship, 14-200
Site 4215
Not yet recruiting
Local Institution - 4208
Katowice, 40-156
Withdrawn
Local Institution - 4205
Katowice, 40-282
Withdrawn
Local Institution - 4213
Kielce, 25-411
Withdrawn
Local Institution - 4217
Lodz, Lódzkie, 90-302
Site 4217
Not yet recruiting
Medycyna Milorzab sp. z o.o.
Lodz, 90-227
Jakub Kazmierski, Site 4202
Recruiting
Pro Salus Sp. z o.o.,sp. k.
Lodz, 91-743
Lukasz Jasek, Site 4214
Recruiting
Osrodek Badan Klinicznych Appletreeclinics
Lódz, Lódzkie, 90-349
Elzbieta Wagenknecht, Site 4207, +48602242959
Recruiting
NZOZ NEUROMED M. I M. Nastaj Spolka Partnerska -Lublin
Lublin, 20-064
Marcin Nastaj, Site 4206, +48793418181
Recruiting
Centrum Medyczne HCP Szpital im. Jana Pawla II
Poznan, Greater Poland Voivodeship, 61-485
Przemyslaw Osip, Site 4210, 48604116632
Recruiting
Osrodek Badawczo Naukowo Dydaktyczny Chorób Otepiennych im Ksiedza Henryka Kardynala Gulbinowicza
Ścinawa, 59-330
Izabela Winkel, Site 4201, +48609034771
Recruiting
Local Institution - 4209
Siemianowice Śląskie, 41-100
Withdrawn
Local Institution - 4216
Sochaczew, 96-500
Site 4216
Not yet recruiting
Local Institution - 4211
Wroclaw, 50-981
Withdrawn

Other trials in Poland

South Korea17 sites, 10 recruiting

Local Institution - 7214
Ansan-si, Gyeonggido, 15355
Withdrawn
Local Institution - 7208
Buk-gu, Daegu Gwang'yeogsi, 41404
Withdrawn
Hallym University Chuncheon Sacred Heart Hospital
Gangwon-do, 200-704
Do-Hoon Kim, Site 7218, 821041512959
Recruiting
Local Institution - 7205
Incheon, Incheon Gwang'yeogsi, 21565
Withdrawn
Local Institution - 7207
Seongnam-si, Gyeonggido, 13496
Withdrawn
Local Institution - 7202
Seongnam-si, 0
Withdrawn
Seoul National University Hospital
Seoul, Seoul Teugbyeolsi, 03080
Manho Kim, Site 7206, +82-2-2072-2193
Recruiting
Local Institution - 7217
Seoul, Seoul Teugbyeolsi, 06591
Site 7217
Not yet recruiting
Local Institution - 7213
Seoul, Seoul Teugbyeolsi, 07804
Site 7213
Not yet recruiting
Ewha Womans University Mokdong Hospital
Seoul, Seoul Teugbyeolsi, 7985
Geon Ha Kim, Site 7215, 82226505298
Recruiting
Local Institution - 7219
Seoul, 06273
Site 7219
Not yet recruiting
Local Institution - 7203
Seoul, 07071
Withdrawn
Local Institution - 7201
Seoul, 143-729
Withdrawn
Hanyang University Seoul Hospital
Seoul, 4763
Hee Jin Kim, Site 7211, +82222908374
Recruiting
Local Institution - 7210
Seoul, 6351
Site 7210
Not yet recruiting
The Catholic University of Korea, Yeouido St. Mary's Hospital
Yeongdeungpo-gu, Seoul Teugbyeolsi, 07345
Hyun-Kook Lim, Site 7212
Recruiting
Local Institution - 7216
Yongin-si, Gyeonggido, 16995
Site 7216
Not yet recruiting

Other trials in South Korea

Brazil13 sites, 7 recruiting

Local Institution - 1-13J38ZST
Brasília, Federal District, 70200-730
Withdrawn
Local Institution - 6201
Brasília, Federal District, 70200-730
Site 6201
Not yet recruiting
Local Institution - 1-13J338E3
Rio de Janeiro, 22270060
Withdrawn
Ruschel Medicina
Rio de Janeiro, 22270060
Sandra Ruschel, Site 6204, 5521999822072
Recruiting
CPQuali Pesquisa Clínica Sao Paulo
São Paulo, São Paulo, 01228-000
Leonel Takada, Site 6202, 558888888888
Recruiting
Local Institution - 1-13J38ZS5
São Paulo, São Paulo, 01228-000
Withdrawn
BR Trials - Pesquisa Clínica
São Paulo, São Paulo, 01236-030
Acioly Lacerda, Site 6206, +551938639438
Recruiting
Local Institution - 1-13J38ZTW
São Paulo, São Paulo, 01236-030
Withdrawn
Local Institution - 6207
São Paulo, São Paulo, 01327-001
Site 6207
Not yet recruiting
Local Institution - 1-13J38ZSH
São Paulo, São Paulo, 05403-010
Withdrawn
Local Institution - 1-13J38ZRS
São Paulo, São Paulo, 87013-250
Withdrawn
Local Institution - 6203
São Paulo, São Paulo, 87013-250
Site 6203
Not yet recruiting
Instituto de Psiquiatria HC FMUSP
São Paulo, 05403-010
Tania Correa de Toledo Ferraz, Site 6205
Recruiting

Other trials in Brazil

Serbia13 sites, 10 recruiting

Local Institution - 4307
Belgrade, Belgrade, 101403
Withdrawn
Local Institution - 4302
Belgrade, Belgrade, 11000
Site 4302
Not yet recruiting
Clinical Hospital Center Dragisa Misovic Dedinje
Belgrade, 11000
Vladimir Diligenski, Site 4306, +381637708765
Recruiting
Local Institution - 4308
Belgrade, 11000
Site 4308
Not yet recruiting
Military Medical Academy
Belgrade, 11000
Ranko Raicevic, Site 4304, 381113609206
Recruiting
Local Institution - 1-13JAX17Q
Gornja Toponica, 705631
Withdrawn
Special Hospital for Psychiatric Diseases "Gornja Toponica"
Gornja Toponica, 705631
Milan Stanojkovic, Site 4312, 382+11
Recruiting
Special Hospital for Psychiatric Diseases Kovin
Kovin, 26220
Jovanka Petrovic, Site 4305, +38163529054
Recruiting
Local Institution - 4301
Kragujevac, 34000
Site 4301
Not yet recruiting
Local Institution - 4310
Kragujevac, 34000
Site 4310
Not yet recruiting
University Clinical Center Kragujevac
Kragujevac, 34000
Dragana Ignjatovic Ristic, Site 4303, +38163685994
Recruiting
Local Institution - 4309
Novi Sad, 21000
Site 4309
Not yet recruiting
Local Institution - 4311
Vršac, 26300
Withdrawn

Other trials in Serbia

Spain11 sites, 8 recruiting

Local Institution - 2205
Barcelona, 8028
Withdrawn
Local Institution - 2212
Lleida, 25198
Withdrawn
Local Institution - 2207
Madrid, 28006
Withdrawn
Hospital Clinico San Carlos
Madrid, 28040
Jordi Matias Guiu, Site 2210
Recruiting
Local Institution - 2211
Majadahonda, Madrid, 28222
Site 2211
Not yet recruiting
Local Institution - 2213
Málaga, Málaga, 29004
Site 2213
Not yet recruiting
Complejo Asistencial Universitario de Salamanca - H. Clinico
Salamanca, 37007
Angel Montejo Gonzalez, Site 2204, +34923126580
Recruiting
Local Institution - 2201
Seville, 41009
Site 2201
Not yet recruiting
Hospital Universitario Rio Hortega
Valladolid, 47012
Juan Muñoz Sanchez, Site 2203, +34679279973
Recruiting
Local Institution - 2202
Zamora, 49021
Site 2202
Not yet recruiting
Hospital Viamed Montecanal
Zaragoza, 50012
Antonio Oliveros-Cid, Site 2206, +34670492099
Recruiting

Other trials in Spain

Argentina9 sites, 9 recruiting

Local Institution - 5002
Buenos Aires, 1199
Site 5002
Not yet recruiting
Organización Médica de Investigación
Buenos Aires, C1015ABO
Daniel Politis, Site 5009, +541150319700
Recruiting
Local Institution - 5006
Buenos Aires, C1428AQK
Site 5006
Not yet recruiting
Local Institution - 5004
Ciudad Autónoma de Buenos Aires, Buenos Aires, 1056
Site 5004
Not yet recruiting
Local Institution - 5005
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1058AAJ
Site 5005
Not yet recruiting
Local Institution - 5001
Ciudad Autónoma de Buenos Aires, Buenos Aires, C1107
Site 5001
Not yet recruiting
Local Institution - 5007
Córdoba, 5000
Site 5007
Not yet recruiting
Local Institution - 5003
Córdoba, 5004
Site 5003
Not yet recruiting
Local Institution - 5008
Rosario, Santa Fe Province, S2000DEJ
Site 5008
Not yet recruiting

Other trials in Argentina

United Kingdom9 sites

Local Institution - 2105
Aberdeen, AB25 2ZL
Withdrawn
Local Institution - 2109
Chertsey, KT16 9AU
Withdrawn
Local Institution - 2110
Ilford, Greater London, IG1 4HP
Withdrawn
Local Institution - 2106
Leeds, LS7 3JX
Withdrawn
Local Institution - 2104
Motherwell, ML1 4UF
Withdrawn
Local Institution - 2111
Preston, PR2 9HT
Withdrawn
Local Institution - 2107
Sheffield, SouthYorkshire, s5 7JT
Withdrawn
Local Institution - 2103
Swindon, SN3 6BW
Withdrawn
Local Institution - 2108
Swinton, Greater Manchester, M27 8FF
Withdrawn

Other trials in United Kingdom

Bulgaria8 sites, 6 recruiting

Medical Center Medconsult Pleven OOD
Pleven, 5800
Maria Aleksandrova, Site 4503, +35964910999
Recruiting
University Multiprofile Hospital for Active Treatment Sveti Georgi EAD-66 Peshtersko Shosse blvd
Plovdiv, 4001
Penka Atanasova, Site 4508
Recruiting
University Multiprofile Hospital For Active Treatment Kanev AD
Rousse, 7002
Neli Petrova, Site 4507, 359888793906
Recruiting
Local Institution - 4505
Sofia, Sofia-Grad, 1431
Withdrawn
Local Institution - 4502
Sofia, Sofia-Grad, 1510
Withdrawn
Local Institution - 4506
Sofia, Sofia-Grad, 1680
Site 4506
Not yet recruiting
Medical Center Sveti Naum EOOD
Sofia, 1113
Assen Karadaliev, Site 4501, +359888220704
Recruiting
Local Institution - 4509
Sofia, 1164
Site 4509
Not yet recruiting

Other trials in Bulgaria

Germany8 sites, 3 recruiting

Local Institution - 2403
Bayreuth, Bavaria, 95445
Withdrawn
Local Institution - 2401
Böblingen, Baden-Wurttemberg, 71034
Withdrawn
Local Institution - 2407
Böblingen, Baden-Wurttemberg, 71034
Site 2407
Not yet recruiting
Local Institution - 1-13JED8BL
Erbach im Odenwald, Hesse, 64711
Withdrawn
Local Institution - 2404
Erbach im Odenwald, 64711
Site 2404
Not yet recruiting
Local Institution - 1-13JED842
Frankfurt am Main, 60528
Withdrawn
Local Institution - 2405
Frankfurt am Main, 60528
Site 2405
Not yet recruiting
Local Institution - 2402
Homburg, Saarland, 66424
Withdrawn

Other trials in Germany

Hungary8 sites, 4 recruiting

Local Institution - 4602
Budapest, 1083
Site 4602
Not yet recruiting
Local Institution - 4612
Budapest, 1123
Site 4612
Not yet recruiting
Local Institution - 1-13JED8D1
Gyöngyös, 3200
Withdrawn
Local Institution - 4611
Gyöngyös, 3200
Site 4611
Not yet recruiting
Local Institution - 4603
Miskolc, 3526
Withdrawn
Local Institution - 4601
Pécs, Baranya, 7633
Site 4601
Not yet recruiting
Local Institution - 1-13JED893
Szeged, Csongrád megye, 6720
Withdrawn
Local Institution - 4610
Szeged, Csongrád megye, 6720
Withdrawn

Other trials in Hungary

Ukraine8 sites, 8 recruiting

Local Institution - 8003
Khmelnytskyi, 32120
Site 8003
Not yet recruiting
Local Institution - 8007
Lviv, Lviv Oblast, 79053
Site 8007
Not yet recruiting
Local Institution - 8006
Lviv, 79035
Site 8006
Not yet recruiting
Local Institution - 8004
Smila, 20708
Site 8004
Not yet recruiting
Local Institution - 8008
Ternopil, 46027
Site 8008
Not yet recruiting
Local Institution - 8005
Uzhhorod, 88000
Site 8005
Not yet recruiting
Local Institution - 8002
Vinnytsia, Vinnytsia Oblast, 21005
Site 8002
Not yet recruiting
Local Institution - 8001
Vinnytsia, Vinnytsia Oblast, Ukraine
Site 8001
Not yet recruiting

Other trials in Ukraine

Belgium7 sites, 3 recruiting

Local Institution - 1-13JED87R
Alken, 3570
Withdrawn
Local Institution - 2804
Alken, 3570
Completed
Local Institution - 2801
Hasselt, Limburg, 3500
Withdrawn
Local Institution - 2806
Jette, Brussels Capital, 1090
Site 2806
Not yet recruiting
Local Institution - 2805
Kortrijk, 8500
Site 2805
Not yet recruiting
Local Institution - 2802
Leuven, Vlaams Brabant, 3000
Withdrawn
Local Institution - 2803
Roeselare, West-Vlaanderen, 8800
Site 2803
Not yet recruiting

Other trials in Belgium

Croatia7 sites, 5 recruiting

Klinicki Bolnicki Centar Zagreb
Zagreb, City of Zagreb, 10000
Natasa Klepac, Site 4105, 38598541880
Recruiting
Local Institution - 1-140R4546
Zagreb, City of Zagreb, 10000
Withdrawn
Local Institution - 4102
Zagreb, City of Zagreb, 10000
Site 4102
Not yet recruiting
Local Institution - 4103
Zagreb, City of Zagreb, 10000
Withdrawn
Local Institution - 4106
Zagreb, City of Zagreb, 10000
Site 4106
Not yet recruiting
Klinika za psihijatriju Vrapce
Zagreb, City of Zagreb, 10090
Ninoslav Mimica, Site 4101, +38513780678
Recruiting
Local Institution - 4104
Zagreb, City of Zagreb, 10090
Site 4104
Not yet recruiting

Other trials in Croatia

Greece7 sites, 1 recruiting

Local Institution - 4805
Athens, Attica, 115 21
Withdrawn
Local Institution - 4803
Athens, Attica, 115 26
Withdrawn
Local Institution - 4802
Chaidari, Athens, Attica, 12462
Withdrawn
University General Hospital of Heraklion
Heraklion, 71110
Ioannis Zaganas, Site 4801
Recruiting
Local Institution - 4810
Kalyftaki-N. Kifissia, Attica, 145 64
Withdrawn
Local Institution - 4806
Marousi, Attica, 151 23
Withdrawn
Local Institution - 4811
Thessaloniki, 546 36
Withdrawn

Other trials in Greece

Mexico7 sites, 3 recruiting

Neurociencias Estudios Clinicos S.C.
Culiacán, Sinaloa, 80020
Elmer Lopez Meza, Site 1501, +526677587952
Recruiting
Local Institution - 1506
México, 03100
Withdrawn
Hospital Universitario Dr. Jose Eleuterio González
Monterrey, Nuevo León, 64460
Ricardo Salinas, Site 1503, +528181232436
Recruiting
Local Institution - 1505
Monterrey, Nuevo León, 64620
Withdrawn
Hospital Universitario de Saltillo Dr Gonzalo Valdes Valdes
Saltillo Centro, Coahuila, 25000
Mario Valdes, Site 1502, 528441258992
Recruiting
Local Institution - 1507
Zapopan, Jalisco, 45170
Withdrawn
Local Institution - 1504
Zona Urbana Río Tijuana, Estado de Baja California, 22010
Withdrawn

Other trials in Mexico

Slovakia7 sites, 5 recruiting

MUDr. Beata Dupejova, Neurologicka ambulancia, s.r.o.
Banská Bystrica, 974 04
Beata Dupejova, Site 4401, +421484124549
Recruiting
KONZILIUM s.r.o
Dubnica nad Váhom, 018 41
Magdalena Perichtova, Site 4402, +421424426231
Recruiting
Univerzitna nemocnica L Pasteura Kosice-Rastislavova 43
Košice, Košice Region, 041 90
Slavka Dubinska, Site 4405, +421556152721
Recruiting
EPAMED s.r.o
Košice, 040 01
Eva Palova, Site 4406, +421556402727
Recruiting
Local Institution - 1-13JED85D
Pezinok, 902 18
Withdrawn
Local Institution - 4407
Pezinok, 902 18
Completed
Crystal Comfort, s.r.o.
Vranov nad Topľou, 093 01
Dagmar Breznoscakova, Site 4403, +421574880251
Recruiting

Other trials in Slovakia

India6 sites, 6 recruiting

Local Institution - 7406
Ajmer, Rajasthan, 305001
Site 7406
Not yet recruiting
Local Institution - 7405
Chandigarh, Punjab, 160012
Site 7405
Not yet recruiting
Local Institution - 7403
Hyderabad, 500034
Site 7403
Not yet recruiting
Local Institution - 7404
Kolkata, 700017
Site 7404
Not yet recruiting
Local Institution - 7401
Nagpur, Maharashtra, 440010
Site 7401
Not yet recruiting
Local Institution - 7402
Varanasi, 211 005
Site 7402
Not yet recruiting

Other trials in India

Portugal6 sites, 1 recruiting

Local Institution - 2701
Guimarães, Braga District, 4835-044
Withdrawn
Local Institution - 2704
Lisbon, Lisbon District, 1349-019
Withdrawn
ULS de Santa Maria,EPE - Hospital de Santa Maria - PPDS
Lisbon, 1649-035
Ana Verdelho, Site 2705, 3512178050x50
Recruiting
Local Institution - 2706
Lisbon, 1998-018
Withdrawn
Local Institution - 2703
Matosinhos Municipality, Porto District, 4454-509
Withdrawn
Local Institution - 2702
Torres Vedras, Lisbon District, 2560-280
Withdrawn

Other trials in Portugal

Romania6 sites, 6 recruiting

Local Institution - 1-14JIMILF
Bucharest, 11241
Site 1-14JIMILF
Not yet recruiting
Prof Dr Alexandru Obregia Clinical Psychiatric Hospital- Centrul de Sanatate Mintala
Bucharest, 40874
Mihaela-Cleopatra Rosca, Site 4906, +40745588989
Recruiting
Local Institution - 4902
Constanța, 90123
Site 4902
Not yet recruiting
Local Institution - 4903
Craiova, 200157
Site 4903
Not yet recruiting
CMI Dr. Buhas Ramocea Elena Daniela - Cabinet Medical de Psihiarie
Oradea, Bihor County, 410027
Elena Daniela Buhas Ramocea, Site 4904, 0040747056934
Recruiting
S.C. Carpe Diem SRL
Sibiu, 550281
Cosmina Muntean, Site 4901, 4026944141x5
Recruiting

Other trials in Romania

Turkey (Türkiye)6 sites, 6 recruiting

Hacettepe University Medical Faculty
Ankara, 06230
Gul Yalcin Cakmakli, Site 4706
Recruiting
Local Institution - 4702
Atakum, Samsun, 55139
Site 4702
Not yet recruiting
Local Institution - 4701
Eskişehir, 26040
Site 4701
Not yet recruiting
Local Institution - 4704
Istanbul, 34093
Site 4704
Not yet recruiting
Local Institution - 4705
Izmir, 35210
Site 4705
Not yet recruiting
Local Institution - 4703
Izmir, 35370
Site 4703
Not yet recruiting

Other trials in Turkey (Türkiye)

Canada5 sites

Local Institution - 1-12IRCCNP
Calgary, Alberta, T2N 1N4
Withdrawn
Local Institution - 1603
Hamilton, Ontario, ON L8M 1W9
Withdrawn
Local Institution - 1-12IYJCH7
Montreal, Quebec, H4H 1R3
Withdrawn
Local Institution - 1601
Verdun, Quebec, H4H 1R3
Withdrawn
Local Institution - 1604
Whitby, Ontario, L1N 5S9
Withdrawn

Other trials in Canada

Czechia5 sites, 4 recruiting

Neuroterapie KH, s.r.o
Kutná Hora, 284 01
Slavomír Pietrucha, Site 4001, 420777551077
Recruiting
A-SHINE s.r.o.
Pilsen, 301 00
Lubos Janu, Site 4005, 420777242101
Recruiting
CLINTRIAL s.r.o.
Prague, Praha, Hlavní Mesto, 100 00
Zdenek Solle, Site 4002, +420222510607
Recruiting
Local Institution - 4004
Prague, 140 00
Withdrawn
Local Institution - 4006
Rychnov nad Kněžnou, 516 01
Site 4006
Not yet recruiting

Other trials in Czechia

France5 sites, 3 recruiting

Local Institution - 2510
Nice, Alpes-Maritimes, 06100
Withdrawn
Local Institution - 2501
Reims, Marne, 51100
Withdrawn
Centre Hospitalier Universitaire Hopitaux de Rouen-1 Rue de Germont
Rouen, Seine-Maritime, 76031
David Wallon, Site 2503, +33232888740
Recruiting
Local Institution - 2513
Toulouse, 31059
Site 2513
Not yet recruiting
Local Institution - 2511
Tours, Indre-et-Loire, 37044
Site 2511
Not yet recruiting

Other trials in France

Puerto Rico5 sites, 2 recruiting

Local Institution - 1303
Bayamón, 00961-6910
Withdrawn
Local Institution - 1301
Bayamón, 961
Withdrawn
Local Institution - 1305
Carolina, 983
Withdrawn
Local Institution - 1302
San Juan, 00918-4502
Site 1302
Not yet recruiting
Barbara Diaz Hernandez MD Research Inc
San Juan, 00926-3160
Ileana Fumero-Perez, Site 1304
Recruiting

Other trials in Puerto Rico

Israel4 sites, 4 recruiting

Local Institution - 3103
Ashkelon, Tel Aviv, 7830604
Site 3103
Not yet recruiting
Local Institution - 3101
Jerusalem, Jerusalem, 90000
Site 3101
Not yet recruiting
Local Institution - 3102
Petah Tikva, 49100
Site 3102
Not yet recruiting
Local Institution - 3104
Ramat Gan, 5265601
Site 3104
Not yet recruiting

Other trials in Israel

Chile3 sites, 3 recruiting

Psicomed Estudios Medicos
Antofagasta, 1270244
Luis Barra, Site 6003, +56552240334
Recruiting
Especialidades Medicas L Y S
Las Condes, 7550000
Manuel Lavados Montes, Site 6001, +56222016979
Recruiting
Biomedica Research Group
Providencia, Santiago Metropolitan, 7500000
Sergio Gloger Kojchen, Site 6002, +56226758700
Recruiting

Other trials in Chile

Peru2 sites

Local Institution - 6101
Callao, Callao 2
Withdrawn
Local Institution - 6102
Miraflores, Lima region, 15046
Withdrawn

Other trials in Peru

About this study

This is a Phase 3 global, multicenter, 52-week, open-label extension (OLE) rollover study for subjects completing study CN012-0026, CN012-0027 or CN012-0056. Subjects (randomized or non-randomized) who complete the 38-week CN012-0026 study, 14-week CN012-0027 study or 14-week CN012-0056 study will be eligible to enroll in CN012-0028. The primary objective of the study is to assess the long-term safety and tolerability of KarXT in subjects with psychosis associated with Alzheimer's Disease.

Conditions: Psychosis Associated With Alzheimer's Disease
Being tested: KarXT

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

KarXTDrug
KarXT 20/2 mg TID (total daily dose [TDD] 60/6 mg) KarXT 30/3 mg TID (TDD 90/9 mg) KarXT 40/4 mg TID (TDD 120/12 mg) KarXT 50/5 mg TID (TDD 150/15 mg) KarXT 66.7/6.67 mg TID (TDD 200/20 mg)

Study groups in NCT05980949
Study group	Role	What they receive
KarXT	Experimental	Xanomeline and Trospium Chloride Capsules Receives: Drug: KarXT

What is being measured

The primary outcome is the main question the study is designed to answer.

Incidence of treatment-emergent adverse events (TEAEs)
The number and percentage of participants with TEAEs will be determined
Measured: From initial dose through 14 days after the final dose (up to 54 weeks)

Secondary outcomes (2)

Incidence of serious TEAEs
The number and percentage of participants with serious TEAEs will be determined
Measured: From initial dose through 14 days after the final dose (up to 54 weeks)
Incidence of TEAEs leading to withdrawal
The number and percentage of participants with TEAEs leading to withdrawal will be determined
Measured: From initial dose through 14 days after the final dose (up to 54 weeks)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

11 Jul 20237 Sep 2027

First posted8 Aug 2023
Study start11 Jul 2023
Primary completion7 Sep 2027 (estimated)
Study completion7 Sep 2027 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Psychosis Associated With Alzheimer's DiseaseStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase 3
Primary purpose: Treatment
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 1,000 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT05980949
Sponsor's protocol ID: CN012-0028
Other IDs: CN012-0028, KAR-033, 2023-504151-27, 2023
Status last verified: Oct 2026
First submitted: 31 Jul 2023
Last updated: 16 Oct 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: Yes
FDA-regulated device: No
Individual data sharing: Yes: BMS will provide access to individual anonymized participant data upon request from qualified researchers, and subject to certain criteria. Additional information regarding Bristol Myer Squibb's data sharing policy and process can be found at https://www.bms.com/researchers-and-partners/clinical-trials-and-research.html

Interested in taking part?

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com

855-907-3286

Clinical.Trials@bms.com

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See sites and contacts

RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
Psychosis Associated With Alzheimer's Disease
RecruitingPhase 2
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Psychosis Associated With Alzheimer's Disease
RecruitingPhase 3
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Psychosis Associated With Alzheimer's Disease
Enrolling by invitationPhase 2
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
Psychosis Associated With Alzheimer's Disease
Not yet recruitingPhase 1
A Phase 1, MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03017
Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis

All Psychosis Associated With Alzheimer's Disease trials