Hip FracturesNCT05969561
Emergency Physician-performed Ultrasound-guided Femoral Nerve Blocks in Patients With Hip Fractures.
A study testing ultrasound-guided femoral nerve block and Intravenous or intramuscular pain medication in people with Hip Fractures, run by National Taiwan University Hospital at 1 site in Taiwan.
Trial summary
In this prospective study, emergency physicians perform ultrasound-guided femoral nerve block for patients with hip fractures. We compare the effectiveness of analgesia and patient satisfaction of ultrasound-guided femoral nerve block with liberal use of the pain medicine in the emergency department. Read more about this study
- Who is it for?
- Ages 20 years and older
- Conditions the study is for
- Hip Fractures
- What is being tested?
- ultrasound-guided femoral nerve block and Intravenous or intramuscular pain medication
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 80 participants
- Where
- 1 siteTaiwan
- Study dates
- 3 Jul 2023to 30 Dec 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients older than 20-year-old with hip fractures
- Stay in the emergency department for at lease two hours
Who cannot join
- hemodynamic unstable
- major trauma in addition to hip fractures
- the use of any pain management before the arrival of emergency department
- chronic opioid use
- inability to understood the numerical rating scale after instruction
- allergy to local anesthetics
- coagulopathy
- injection site infection
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Taiwan1 site, 1 recruiting
- Recruiting
NTUH Yunlin Branch
Douliu, Yunlin County, 640
YILIN LEE, +886972655633, leeatntuh@gmail.com
About this study
Official title: Ultrasound-Guided Femoral Nerve Block
In this prospective study, emergency physicians perform ultrasound-guided femoral nerve block for patients with hip fractures. We compare the effectiveness of analgesia and patient satisfaction of ultrasound-guided femoral nerve block with liberal use of the pain medicine in the emergency department. The primary outcome is the assessment of time to relief the pain with fewer adverse effects and less rescue pain medication use. The secondary outcome is patient satisfaction and adverse effects for different method of pain control.
Read the detailed description
The aim of this study is to compare the effectiveness of ultrasound-guided femoral nerve blocks performed by emergency physicians for pain control in the emergency department with traditional pain medicine.
This study is a prospective before-and-after design. The enrollees are 20-year-old and older adult patients with hip fractures. We use numerical rating scale using a 0-10 scale to assess pain severity at the different time frame after giving pain medicine. The scale zero means "no pain" and scale 10 means "the worst pain imaginable".
The primary outcome is assessed by the reduction of pain scale which are taken on a numeric rating scale every 30 minutes before and after pain management. The secondary outcome compares complications, adverse effects and patient satisfaction for different method of pain control.
- Conditions
- Hip Fractures
- Being tested
- ultrasound-guided femoral nerve block, Intravenous or intramuscular pain medication
- Keywords
- Ultrasound-guided femoral nerve block
- Medical subject headings
- Hip Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ultrasound-guided femoral nerve blockProcedure or surgery
The local analgesia is injected and infiltrated around the femoral nerve under ultrasound guidance.
Intravenous or intramuscular pain medicationDrug
Intravenous or intramuscular pain medication is given for patients with hip fracture.
| Study group | Role | What they receive |
|---|---|---|
| Ultrasound-guided femoral nerve block | Active comparator | Patients with hip fractures had underwent Ultrasound-guided femoral nerve block performed by emergency physicians. Receives: Procedure: ultrasound-guided femoral nerve block |
| The liberal use of pain medication | Sham comparator | Patients with hip fractures had given intravenous or intramuscular opioids or NSAID at the emergency department. Receives: Drug: Intravenous or intramuscular pain medication |
What is being measured
The primary outcome is the main question the study is designed to answer.
a short time of pain relief
The numerical pain score from 0 to 10 is used to assess pain severity and the scale 0 means no pain and the scale 10 means the worst pain imaginable. The pain score assessed for the leg with hip fracture at rest and with movement will be recorded after different pain medicine and the reduction of pain score at different time frame will be evaluated. The more reduction of pain score, the better.
Measured: 2 hours
Secondary outcomes (3)
Adverse effects
Any adverse effects of different pain medication
Measured: two hours
Patient satisfaction
The difference of patient satisfaction between ultrasound-guided femoral nerve block and the liberal use of pain medication
Measured: two hours
Complications of ultrasound-guided femoral nerve block
Any complications of ultrasound-guided femoral nerve block
Measured: two hours and one week after ultrasound-guided femoral nerve block or after hospital discharge
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Aug 2023
- Study start3 Jul 2023
- Primary completion5 Mar 2025
- Study completion30 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hip FracturesStudies of the same condition, open and under way.
- More trials run by National Taiwan University HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Masking
- None (open label)
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- National Taiwan University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05969561
- Sponsor's protocol ID
- 202211021RINB
- Status last verified
- Jun 2025
- First submitted
- 23 Jul 2023
- Last updated
- 5 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ultrasound-Guided Femoral Nerve Block
- ClinicalTrials.gov ID
- NCT05969561
- Acronym / sponsor ID
- 202211021RINB
- Conditions
- Hip Fractures
- Keywords
- Ultrasound-guided femoral nerve block
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- National Taiwan University HospitalUniversity, hospital or other
- Study start
- 3 Jul 2023 (actual)
- Primary completion
- 5 Mar 2025 (actual)
- Study completion
- 30 Dec 2025 (estimated)
- First posted
- 1 Aug 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
In this prospective study, emergency physicians perform ultrasound-guided femoral nerve block for patients with hip fractures. We compare the effectiveness of analgesia and patient satisfaction of ultrasound-guided femoral nerve block with liberal use of the pain medicine in the emergency department. The primary outcome is the assessment of time to relief the pain with fewer adverse effects and less rescue pain medication use. The secondary outcome is patient satisfaction and adverse effects for different method of pain control.
Detailed description
The aim of this study is to compare the effectiveness of ultrasound-guided femoral nerve blocks performed by emergency physicians for pain control in the emergency department with traditional pain medicine.
This study is a prospective before-and-after design. The enrollees are 20-year-old and older adult patients with hip fractures. We use numerical rating scale using a 0-10 scale to assess pain severity at the different time frame after giving pain medicine. The scale zero means "no pain" and scale 10 means "the worst pain imaginable".
The primary outcome is assessed by the reduction of pain scale which are taken on a numeric rating scale every 30 minutes before and after pain management. The secondary outcome compares complications, adverse effects and patient satisfaction for different method of pain control.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ultrasound-guided femoral nerve block | Active comparator | Procedure: ultrasound-guided femoral nerve blockPatients with hip fractures had underwent Ultrasound-guided femoral nerve block performed by emergency physicians. |
| The liberal use of pain medication | Sham comparator | Drug: Intravenous or intramuscular pain medicationPatients with hip fractures had given intravenous or intramuscular opioids or NSAID at the emergency department. |
Who may qualify
- Ages
- 20 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Patients older than 20-year-old with hip fractures
- Stay in the emergency department for at lease two hours
Key exclusion criteria (8 listed)
- hemodynamic unstable
- major trauma in addition to hip fractures
- the use of any pain management before the arrival of emergency department
- chronic opioid use
- inability to understood the numerical rating scale after instruction
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ultrasound-guided femoral nerve blockThe local analgesia is injected and infiltrated around the femoral nerve under ultrasound guidance. | Procedure or surgery | Ultrasound-guided femoral nerve block |
| Intravenous or intramuscular pain medicationIntravenous or intramuscular pain medication is given for patients with hip fracture. | Drug | The liberal use of pain medication |
Primary outcome
a short time of pain relief
Time frame: 2 hours
The numerical pain score from 0 to 10 is used to assess pain severity and the scale 0 means no pain and the scale 10 means the worst pain imaginable. The pain score assessed for the leg with hip fracture at rest and with movement will be recorded after different pain medicine and the reduction of pain score at different time frame will be evaluated. The more reduction of pain score, the better.
3 secondary outcomes
Adverse effects
Time frame: two hours
Patient satisfaction
Time frame: two hours
Complications of ultrasound-guided femoral nerve block
Time frame: two hours and one week after ultrasound-guided femoral nerve block or after hospital discharge
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Aug 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ultrasound-guided femoral nerve block and Intravenous or intramuscular pain medication in people with Hip Fractures, run by National Taiwan University Hospital at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact YILIN LEE (+886972655633, leeatntuh@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
a short time of pain relief (time frame: 2 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Aug 2025.