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Muscle StrengthNCT05932875

Peanut Consumption to Augment Adaptations to Concurrent Resistance and Aerobic Exercise Training

A study testing Exercise Training in people with Muscle Strength and Cardiorespiratory Fitness, run by Southwestern University at 1 site in United States.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The primary objective of this proposal is to determine the effects of post-exercise peanut consumption on long-term aerobic and resistance exercise training adaptations in middle-aged men and women. Read more about this study

Who is it for?
Ages 30 to 55 yearsHealthy volunteers can take part
What is being tested?
Exercise Training
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
34 participants
Where
1 siteUnited States
Study dates
30 May 2023to 1 Jul 2024
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 30 to 55 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Men and women 30- 55 years old
  • healthy
  • non-smoking
  • no exercise training in the previous 6 months
  • not currently attempting to gain or lose weight
  • body mass index < 35
  • no need for physician clearance prior to beginning an exercise program as determined by American College of Sports Medicine guidelines.

Who cannot join

  • neurological or musculoskeletal disorders
  • uncontrolled hypertension (resting systolic blood pressure > 180 mmHg or diastolic > 120 mmHg
  • unstable or exercise-induced angina pectoris
  • diabetes mellitus; any other medical condition that would interfere with testing or training
  • androgen (e.g., testosterone), anabolic (e.g., GH, IGF-I), or catabolic (e.g. GLP-1 agonists) therapy
  • food allergy to peanuts or dairy products
  • pregnant people or people actively trying to get pregnant
  • on a special diet that restricts protein/carbs/sugar/fat.

Trial locations and contacts

1 site in 1 country.

United States1 site
  • Southwestern University

    Georgetown, Texas, 78626

Other trials in United States

About this study

The primary objective of this proposal is to determine the effects of post-exercise peanut consumption on long-term aerobic and resistance exercise training adaptations in middle-aged men and women. The investigators will determine the impact of peanuts on exercise training-induced improvements in muscle strength, gains in muscle mass, and improvements in cardiorespiratory fitness and metabolic capacity.

Read the detailed description

Positive health benefits of peanut consumption are well-known, but potential benefits have yet to be discovered, especially in regard to fitness. This project will directly determine the benefits of peanut consumption as part of a long-term aerobic and resistance exercise training program in middle-aged adults.

Proper nutrition is necessary for the body to properly recover and adapt to an exercise bout and thereby realize the health benefits of the exercise. The period of time immediately after exercise is even more important in realizing these adaptations. With relatively higher amounts of fats, peanuts are often overlooked as a nutritious, post-exercise snack, because they might not be optimal for athletic performance. However, for a middle-aged adult performing the recommended amount of weekly physical activity, the protein and carbohydrate content of peanuts is sufficient to provide the macronutrients necessary to achieve the beneficial health adaptations associated with exercise training. Other micronutrients and healthy fats in peanuts, might confer further benefits beyond those of other post-exercise supplements, however, this has yet to be elucidated.

The randomized, placebo-controlled, clinical trial will provide valuable information on the health benefits of peanut consumption and determine if peanuts can augment beneficial exercise training adaptations in middle-aged adults. The investigators will recruit a group of 48 adults (30-55 years) who do not regularly exercise to undertake a 4-month exercise training program. The program, proven to increase muscle mass and improve cardiorespiratory fitness, will consist of 4 days per week of structured workouts (2/week resistance, 2/week aerobic). Participants will be randomly assigned to consume either a peanut-based snack or an isocaloric, non-peanut carbohydrate-based snack immediately after each exercise session. A comprehensive health and fitness assessment will be conducted before training, after 2-months of training, and after 4-months of training. Measures of cardiorespiratory fitness, muscular fitness, and body composition will be assessed.

Anticipated Products \& Potential Outcomes When completed, this study will provide the first evidence of the effect of post-exercise peanut consumption on long-term exercise training adaptations to both aerobic and resistance training in middle-aged adults. This will be the first study to determine the effects of peanut consumption with aerobic exercise training, and the longest study on resistance exercise training and peanut consumption. With the mid-training 2-month timepoint, the investigators will be able to compare our results to those of similar resistance training peanut studies, but importantly follow them for longer, when resistance training adaptations are likely to be more apparent. The investigators hypothesize that the peanut group will experience greater gains in muscle strength and hypertrophy than the placebo group. The investigatorshypothesize that the peanut and placebo group will have similar improvements in cardiorespiratory fitness and body composition (higher total body lean mass leading to relatively lower body fat). This would be an important finding to prove that, despite their higher fat content, peanut consumption does not lead to negative effects on body composition nor prevent cardiorespiratory adaptions due to exercise training. Overall, the results are likely to demonstrate that peanuts are a simple, inexpensive, and effective post-exercise health food capable of further enhancing the beneficial effects of exercise training.

Being tested
Exercise Training
Keywords
peanut, muscle health, concurrent training, cardiorespiratory fitness

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT05932875
Study groupRoleWhat they receive
Peanut/Carbohydrate Consumption Exercise TrainingActive comparatorParticipants in this group will undergo 16 weeks of concurrent exercise training (4 sessions/week) consuming a peanut-based rice/oatmilk smoothie after each workout
Receives: Other: Exercise Training
Carbohydrate Consumption Exercise TrainingPlacebo comparatorParticipants in this group will undergo 16 weeks of concurrent exercise training (4 sessions/week) consuming a rice/oatmilk smoothie after each workout
Receives: Other: Exercise Training

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Total Lean Mass

    Amount of lean mass as determined by dual energy x-ray absorptiometry scan

    Measured: From baseline to the end of the training program at 16 weeks.

  2. Muscle strength

    Isometric grip and knee extension strength, as well as dynamic 1-repitition maximum strength of bench press, leg press, overhead press, knee extension

    Measured: From baseline to the end of the training program at 16 weeks.

  3. Cardiorespiratory fitness

    Maximal oxygen consumption as determined by graded treadmill test

    Measured: From baseline to the end of the training program at 16 weeks.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted6 Jul 2023
  2. Study start30 May 2023
  3. Primary completion15 Jun 2024
  4. Study completion1 Jul 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
34 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT05932875
Sponsor's protocol ID
SP23_20
Status last verified
Apr 2025
First submitted
27 Jun 2023
Last updated
24 Apr 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: IRB approval does not allow for IPD to be shared.

Questions about this trial

What is this clinical trial studying?

A study testing Exercise Training in people with Muscle Strength and Cardiorespiratory Fitness, run by Southwestern University at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 24 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Total Lean Mass (time frame: From baseline to the end of the training program at 16 weeks.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Apr 2025.

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