Advanced CancerRECIFENCT05884788
Study of the Life Stories of Patients Making a Request for Euthanasia, in the Context of Advanced Cancer.
An observational study of Advanced Cancer, run by Centre Leon Berard at 1 site in France.
Trial summary
This study wishes to focus on the life course of patients, beyond the moments of suffering experienced at the time of the request for euthanasia. It is based on the perspective that the patient's account of his or her life course can be a source of information for better understanding and accompanying patients… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Advanced Cancer
- What is being tested?
- free interview, and questionnaires in a second time
- How many people
- 7 participants
- Where
- 1 siteFrance
- Study dates
- 1 Jun 2023to 31 Jul 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: We conduct our study in a French cancer center and a French public hospital. Patients requesting euthanasia will be informed about the possibility of participating in our study. If the patients agree, and if they meet the study criteria, they will be included.
Who may be able to join
- Major patients
- With cancer in the palliative phase, i.e. with an incurable disease according to current knowledge.
- Expressing a request for euthanasia in terms evoking a request for death with the intervention of an outside person.
- Non-opposition to the study after full written information.
Who cannot join
- Severe decompensated psychiatric pathology
- Vulnerable persons defined here as pregnant women, parturients and persons under legal protection or unable to express their consent
- Inability to conduct an interview
Trial locations and contacts
1 site in 1 country.
About this study
This study wishes to focus on the life course of patients, beyond the moments of suffering experienced at the time of the request for euthanasia. It is based on the perspective that the patient's account of his or her life course can be a source of information for better understanding and accompanying patients requesting euthanasia.
- Conditions
- Advanced Cancer
- Being tested
- free interview, and questionnaires in a second time
- Keywords
- Euthanasia, Cancer
- Medical subject headings
- Suicide, Assisted, Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
free interview, and questionnaires in a second timeOther
After inclusion in the study, patients will be met for a free interview. The interview will be conducted using an open-ended interview method with the patients to allow free expression of their life history, using open and broad questions to avoid the influence of the interviewer as much as possible.
Each interview will be conducted by the same person to allow for better interpersonal reproducibility.
After the interview, the patients will be seen again to complete two questionnaires:
- An attachment questionnaire: Relationship Scales Questionnaire
- A questionnaire on symptoms: Distress thermometer
What is being measured
The primary outcome is the main question the study is designed to answer.
Description of the life stories of patients requesting euthanasia to explore which life experiences are brought forward when making this request, in a context of advanced oncological pathology.
The main objective is to describe the life stories of patients requesting euthanasia in order to discover which life experiences are reasoning in the formulation of this request, in a context of advanced oncological pathology.
The investigators carry out a descriptive analysis of the interviews. The interviews will be analyzed as they are conducted, in order to identify themes of interest. The themes will be compared between the different interviews in order to identify possible trends.
Measured: One month
Secondary outcomes (2)
Calculation of the Bartholomew score
Use of specific questionnaire (Relationship Scales Questionnaire of Batholomew) to describe the profiles of the patients in the study
Measured: One month
Calculation of the distress thermometer's score
Use of specific questionnaire (NCCN distress thermometer) to describe the profiles of the patients in the study
Measured: One month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jun 2023
- Study start1 Jun 2023
- Primary completion31 Jul 2024
- Study completion31 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Advanced CancerStudies of the same condition, open and under way.
- More trials run by Centre Leon BerardThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 7 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Leon Berard
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05884788
- Sponsor's protocol ID
- ET22000324
- Acronym
- RECIFE
- Status last verified
- Apr 2025
- First submitted
- 9 May 2023
- Last updated
- 16 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 16 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Study of the Life Stories of Patients Making a Request for Euthanasia, in the Context of Advanced Cancer.
- ClinicalTrials.gov ID
- NCT05884788
- Acronym / sponsor ID
- RECIFE / ET22000324
- Conditions
- Advanced Cancer
- Keywords
- Euthanasia, Cancer
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 7 participants (actual)
- Lead sponsor
- Centre Leon BerardUniversity, hospital or other
- Study start
- 1 Jun 2023 (actual)
- Primary completion
- 31 Jul 2024 (actual)
- Study completion
- 31 Jul 2024 (actual)
- First posted
- 1 Jun 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study wishes to focus on the life course of patients, beyond the moments of suffering experienced at the time of the request for euthanasia. It is based on the perspective that the patient's account of his or her life course can be a source of information for better understanding and accompanying patients requesting euthanasia.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- We conduct our study in a French cancer center and a French public hospital. Patients requesting euthanasia will be informed about the possibility of participating in our study. If the patients agree, and if they meet the study criteria, they will be included.
Key inclusion criteria (4 listed)
- Major patients
- With cancer in the palliative phase, i.e. with an incurable disease according to current knowledge.
- Expressing a request for euthanasia in terms evoking a request for death with the intervention of an outside person.
- Non-opposition to the study after full written information.
Key exclusion criteria (3 listed)
- Severe decompensated psychiatric pathology
- Vulnerable persons defined here as pregnant women, parturients and persons under legal protection or unable to express their consent
- Inability to conduct an interview
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| free interview, and questionnaires in a second timeAfter inclusion in the study, patients will be met for a free interview. The interview will be conducted using an open-ended interview method with the patients to allow free expression of their life history, using open and broad questions to avoid the influence of the interviewer as much as possible. Each interview will be conducted by the same person to allow for better interpersonal reproducibility. After the interview, the patients will be seen again to complete two questionnaires: * An attachment questionnaire: Relationship Scales Questionnaire * A questionnaire on symptoms: Distress thermometer | Other | – |
Primary outcome
Description of the life stories of patients requesting euthanasia to explore which life experiences are brought forward when making this request, in a context of advanced oncological pathology.
Time frame: One month
The main objective is to describe the life stories of patients requesting euthanasia in order to discover which life experiences are reasoning in the formulation of this request, in a context of advanced oncological pathology. The investigators carry out a descriptive analysis of the interviews. The interviews will be analyzed as they are conducted, in order to identify themes of interest. The themes will be compared between the different interviews in order to identify possible trends.
2 secondary outcomes
Calculation of the Bartholomew score
Time frame: One month
Calculation of the distress thermometer's score
Time frame: One month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Apr 2025.
- Individual participant dataSharing planned: Undecided
Related trials for Advanced Cancer
Enrolling by invitationPhase 2
A Single-Arm Study of Nimotuzumab Combined With NALIRIFOX as First-Line Treatment for Pancreatic Cancer
Pancreatic Cancer Metastatic
RecruitingPhase 1/2
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Solid Tumor, Non-Small Cell Lung Cancer
Active, not recruitingPhase 3
A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)
Carcinoma, Renal Cell
RecruitingPhase 3
A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)
Non-Small Cell Lung Cancer (NSCLC)
Active, not recruitingPhase 1
A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK043 in Patients With Advanced Solid Tumor
Neoplasms
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Advanced Cancer, run by Centre Leon Berard at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Description of the life stories of patients requesting euthanasia to explore which life experiences are brought forward when making this request, in a context of advanced oncological pathology. (time frame: One month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Apr 2025.