HealthyNCT05821504
High-Intensity Interval Training and Performance
A study testing High-Intensity Interval Training in people with Healthy, run by Kennesaw State University at 1 site in United States.
Trial summary
The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions?… Read more about this study
- Who is it for?
- Ages 18 to 35 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- High-Intensity Interval Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Aug 2018to 21 Nov 2018
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Between 18-35 years of age
- Female
- Currently participating in 2-4 days of structured exercise for 30-75 minutes for the last 6 months
Who cannot join
- Currently participating in these exercise formats (2x/week within last 3 months)
- Engaging in high intensity interval training for more than 30 min/week
- Have diagnosed disorders/diseases in the following: cardiovascular, pulmonary, immunological, or metabolic
- Current musculoskeletal injuries
- Pregnant or think you may be pregnant
- Currently taking any non-steroidal anti-inflammatory drug(s) or steroidal drug(s)
Show all 10Show fewer
- Currently a smoker or has consistently smoked within the last year
- Has a positive written or verbal pre-study drug screen including alcohol (more than 7 drinks/week), THC/cannabinoids, amphetamines, benzodiazepines, cocaine, opioids, phencyclidine, barbiturates, cotinine.
- Currently taking any medication that will significantly affect your heart rate response to exercise
- If you miss four or more classes, you will be excluded from the study
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Plyometric- and Cycle-Based High-Intensity Interval Training on Body Composition, Aerobic Capacity, and Muscle Function in Young Females: a Field-based Group Fitness Assessment
The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions? Participants were randomized to 8 weeks of high-intensity interval training involving body weight, plyometric exercises or cycling only. Researchers compared changes in endurance performance, body composition, and muscle performance to determine if there were differences between groups.
Read the detailed description
The purpose of this study was to compare the effects of plyometric- and cycle-oriented high-intensity interval training on body composition, aerobic capacity, and skeletal muscle size, quality, and function in recreationally trained females. Young (21.7 ± 3.1 yrs), recreationally active females were randomly assigned to 8 weeks of twice weekly plyometric (n = 15) or cycling (n = 15) high-intensity interval training. The plyometric-oriented Les Mills BODYATTACK program was used for the plyometric group whereas Les Mills SPRINT, which exclusively involves stationary cycling, represented the cycling group. Both protocols involved alternating high-intensity and recovery intervals, and participants were consistently instructed to give maximal effort during the 'work' periods.
The 30 min plyometric routines included four blocks of high-intensity exercise intervals. The 'work' portions consisted of the following exercises: high-knee runs, plyometric lunges, jumping jacks, squat jumps, burpees, and speed-agility patterns. The recovery periods consisted of complete rest (transitioning between exercises), a light jog, or a low impact stepping motion. On average, participants were instructed to give maximal effort for 1-2 min, with recovery intervals of 15-45 sec. Four separate routines were used throughout the duration of the study, keeping one routine per week; participants completed each routine a total of 4 times within a session.
The 30 min cycling routines were performed on upright stationary bikes (Schwinn, AC Performance, Chicago, IL). Protocols involved 'work' ranging from 20-80 sec with recovery intervals between 10-60 sec. Recovery intervals consisted of complete rest on bike or particularly slow cycling. Resistance and cycling speed were relatively variable across sessions, with some intervals of higher resistance and lower speed and others involving lower resistance and higher speed (e.g., >120 RPMs). The same four workouts were used throughout the duration of the study alternating each week.
Body composition (4-compartment model), VO2peak, countermovement jump performance, muscle size and echo intensity (muscle quality) as well as strength and power of the knee extensors and plantar flexors were measured before and after training. Body composition testing was completing using dual-energy x-ray absorpiometry, air displacement plethysmogrphay, and bioeletrical impedance. VO2peak was measured using a standardized maximal exercise test on a treadmill. Countermovement jump height and power was recorded with participants performing jumps on a force plate. Muscle size and quality were determined using non-invasive ultrasonography. Finally, serum growth hormone responses to the VO2peak test were measured before and after the protocols.
- Conditions
- Healthy
- Being tested
- High-Intensity Interval Training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High-Intensity Interval TrainingBehavioural
The training intervention is a popular exercise format that consist of alternating brief bouts of high-intensity efforts with bouts of light effort or complete rest.
| Study group | Role | What they receive |
|---|---|---|
| Plyometric High-Intensity Interval Training | Experimental | This group performed high-intensity interval training consisting of body-weight, plyometric exercises involving jumping. Receives: Behavioral: High-Intensity Interval Training |
| Cycling High-Intensity Interval Training | Experimental | This group performed high-intensity interval training consisting of cycling exercise. Receives: Behavioral: High-Intensity Interval Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Muscle composition at baseline
echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle
Measured: Pre-intervention
Muscle composition after 8-week intervention
echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle
Measured: At week 9
Secondary outcomes (20)
Fat mass at baseline
Amount of fat tissue a person possesses
Measured: Pre-intervention
Fat mass after 8-week intervention
Amount of fat tissue a person possesses
Measured: At week 9
Group average growth hormone response (concentration at microLiters/Liters) at baseline
The acute, exercise-induced response for growth hormone
Measured: Pre-intervention
Group average growth hormone response (concentration at microLiters/Liters) after 8-week intervention
The acute, exercise-induced response for growth hormone
Measured: At week 9
Countermovement jump height at baseline
Height of jump
Measured: Pre-intervention
Countermovement jump height after 8-week intervention
Height of jump
Measured: At week 9
Time to peak torque at baseline
How quickly muscle torque is generated
Measured: Pre-intervention
Time to peak torque after 8-week intervention
How quickly muscle torque is generated
Measured: At week 9
Maximal oxygen consumption at baseline
Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise
Measured: Pre-intervention
Maximal oxygen consumption after 8-week intervention
Standard measure of maximal oxygen consumption or peak aerobic capacity during exercise
Measured: At week 9
Body fat percentage at baseline
Relative amount of body fat a person possesses
Measured: Pre-intervention
Body fat percentage after 8-week intervention
Relative amount of body fat a person possesses
Measured: At week 9
Fat-free mass at baseline
Amount of non-fat tissue a person possesses
Measured: Pre-intervention
Fat-free mass after 8-week intervention
Amount of non-fat tissue a person possesses
Measured: At week 9
Peak torque at baseline
Strength of a muscle
Measured: Pre-intervention
Peak torque after 8-week intervention
Strength of a muscle
Measured: At week 9
Muscle cross-sectional area at baseline
The size of a muscle
Measured: Pre-intervention
Muscle cross-sectional area after 8-week intervention
The size of a muscle
Measured: At week 9
Muscle power at baseline
Product of torque and velocity as determined on a dynamometer
Measured: Pre-intervention
Muscle power after 8-week intervention
Product of torque and velocity as determined on a dynamometer
Measured: At week 9
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Apr 2023
- Study start1 Aug 2018
- Primary completion21 Nov 2018
- Study completion21 Nov 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two groups performed different types of high-intensity interval training
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Kennesaw State University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Garrett Hester, Kennesaw State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05821504
- Sponsor's protocol ID
- 2022-0465
- Status last verified
- Jun 2023
- First submitted
- 14 Mar 2023
- Last updated
- 13 Jun 2023
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share.
Publications
Holmes AJ, Stratton MT, Bailly AR, Gottschall JS, Feito Y, Ha PL, Lavigne A, Persaud K, Gagnon HL, Krueger A, Modjeski A, Esmat TA, Harper LN, VanDusseldorp TA, Hester GM. Effects of plyometric- and cycle-based high-intensity interval training on body composition, aerobic capacity, and muscle function in young females: a field-based group fitness assessment. Appl Physiol Nutr Metab. 2023 Dec 1;48(12):932-945. doi: 10.1139/apnm-2022-0465. Epub 2023 Aug 9.
PubMed 37556856
Study at a glance
From the registry record, last updated by the sponsor on 13 Jun 2023. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Plyometric- and Cycle-Based High-Intensity Interval Training on Body Composition, Aerobic Capacity, and Muscle Function in Young Females: a Field-based Group Fitness Assessment
- ClinicalTrials.gov ID
- NCT05821504
- Acronym / sponsor ID
- 2022-0465
- Conditions
- Healthy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Kennesaw State UniversityUniversity, hospital or other
- Study start
- 1 Aug 2018 (actual)
- Primary completion
- 21 Nov 2018 (actual)
- Study completion
- 21 Nov 2018 (actual)
- First posted
- 20 Apr 2023 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial was to compare to different types of high-intensity interval training in young, healthy females. The main questions were: Will changes in body composition differ between the two interventions? Will changes in endurance and muscle performance differ between the two interventions? Participants were randomized to 8 weeks of high-intensity interval training involving body weight, plyometric exercises or cycling only. Researchers compared changes in endurance performance, body composition, and muscle performance to determine if there were differences between groups.
Detailed description
The purpose of this study was to compare the effects of plyometric- and cycle-oriented high-intensity interval training on body composition, aerobic capacity, and skeletal muscle size, quality, and function in recreationally trained females. Young (21.7 ± 3.1 yrs), recreationally active females were randomly assigned to 8 weeks of twice weekly plyometric (n = 15) or cycling (n = 15) high-intensity interval training. The plyometric-oriented Les Mills BODYATTACK program was used for the plyometric group whereas Les Mills SPRINT, which exclusively involves stationary cycling, represented the cycling group. Both protocols involved alternating high-intensity and recovery intervals, and participants were consistently instructed to give maximal effort during the 'work' periods.
The 30 min plyometric routines included four blocks of high-intensity exercise intervals. The 'work' portions consisted of the following exercises: high-knee runs, plyometric lunges, jumping jacks, squat jumps, burpees, and speed-agility patterns. The recovery periods consisted of complete rest (transitioning between exercises), a light jog, or a low impact stepping motion. On average, participants were instructed to give maximal effort for 1-2 min, with recovery intervals of 15-45 sec. Four separate routines were used throughout the duration of the study, keeping one routine per week; participants completed each routine a total of 4 times within a session.
The 30 min cycling routines were performed on upright stationary bikes (Schwinn, AC Performance, Chicago, IL). Protocols involved 'work' ranging from 20-80 sec with recovery intervals between 10-60 sec. Recovery intervals consisted of complete rest on bike or particularly slow cycling. Resistance and cycling speed were relatively variable across sessions, with some intervals of higher resistance and lower speed and others involving lower resistance and higher speed (e.g., >120 RPMs). The same four workouts were used throughout the duration of the study alternating each week.
Body composition (4-compartment model), VO2peak, countermovement jump performance, muscle size and echo intensity (muscle quality) as well as strength and power of the knee extensors and plantar flexors were measured before and after training. Body composition testing was completing using dual-energy x-ray absorpiometry, air displacement plethysmogrphay, and bioeletrical impedance. VO2peak was measured using a standardized maximal exercise test on a treadmill. Countermovement jump height and power was recorded with participants performing jumps on a force plate. Muscle size and quality were determined using non-invasive ultrasonography. Finally, serum growth hormone responses to the VO2peak test were measured before and after the protocols.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Two groups performed different types of high-intensity interval training
| Arm | Type | Receives |
|---|---|---|
| Plyometric High-Intensity Interval Training | Experimental | Behavioral: High-Intensity Interval TrainingThis group performed high-intensity interval training consisting of body-weight, plyometric exercises involving jumping. |
| Cycling High-Intensity Interval Training | Experimental | Behavioral: High-Intensity Interval TrainingThis group performed high-intensity interval training consisting of cycling exercise. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Between 18-35 years of age
- Female
- Currently participating in 2-4 days of structured exercise for 30-75 minutes for the last 6 months
Key exclusion criteria (10 listed)
- Currently participating in these exercise formats (2x/week within last 3 months)
- Engaging in high intensity interval training for more than 30 min/week
- Have diagnosed disorders/diseases in the following: cardiovascular, pulmonary, immunological, or metabolic
- Current musculoskeletal injuries
- Pregnant or think you may be pregnant
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High-Intensity Interval TrainingThe training intervention is a popular exercise format that consist of alternating brief bouts of high-intensity efforts with bouts of light effort or complete rest. | Behavioural | Cycling High-Intensity Interval Training, Plyometric High-Intensity Interval Training |
Primary outcome
Muscle composition at baseline
Time frame: Pre-intervention
echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle
Muscle composition after 8-week intervention
Time frame: At week 9
echo-intensity value derived from ultrasound that indicates the amount of fat infiltration in muscle
20 secondary outcomes
Fat mass at baseline
Time frame: Pre-intervention
Fat mass after 8-week intervention
Time frame: At week 9
Group average growth hormone response (concentration at microLiters/Liters) at baseline
Time frame: Pre-intervention
Group average growth hormone response (concentration at microLiters/Liters) after 8-week intervention
Time frame: At week 9
Countermovement jump height at baseline
Time frame: Pre-intervention
Countermovement jump height after 8-week intervention
Time frame: At week 9
Time to peak torque at baseline
Time frame: Pre-intervention
Time to peak torque after 8-week intervention
Time frame: At week 9
Maximal oxygen consumption at baseline
Time frame: Pre-intervention
Maximal oxygen consumption after 8-week intervention
Time frame: At week 9
Body fat percentage at baseline
Time frame: Pre-intervention
Body fat percentage after 8-week intervention
Time frame: At week 9
Fat-free mass at baseline
Time frame: Pre-intervention
Fat-free mass after 8-week intervention
Time frame: At week 9
Peak torque at baseline
Time frame: Pre-intervention
Peak torque after 8-week intervention
Time frame: At week 9
Muscle cross-sectional area at baseline
Time frame: Pre-intervention
Muscle cross-sectional area after 8-week intervention
Time frame: At week 9
Muscle power at baseline
Time frame: Pre-intervention
Muscle power after 8-week intervention
Time frame: At week 9
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Jun 2023.
- Derived from this study: PubMed 37556856Holmes AJ, Stratton MT, Bailly AR, Gottschall JS, Feito Y, Ha PL, Lavigne A, Persaud K, Gagnon HL, Krueger A, Modjeski A, Esmat TA, Harper LN, VanDusseldorp TA, Hester GM. Effects of plyometric- and cycle-based high-intensity interval training on body composition, aerobic capacity, and muscle function in young females: a field-based group fitness assessment. Appl Physiol Nutr Metab. 2023 Dec 1;48(12):932-945. doi: 10.1139/apnm-2022-0465. Epub 2023 Aug 9.
- Individual participant dataSharing planned: No. There is no plan to share.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High-Intensity Interval Training in people with Healthy, run by Kennesaw State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Jun 2023. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Muscle composition at baseline (time frame: Pre-intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05821504, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Jun 2023.