Old Age; AtrophyNCT05586087
High-Speed Resistance Training Program in Independent Older Adults
A study testing Experimental group in people with Old Age; Atrophy and Aging, run by University of Évora at 1 site in Portugal.
Trial summary
The aims of the present investigation are: a) to determine the effects of a 16-weeks high-speed resistance training program on health parameters in independent older adults; and b) to verify the durability of the effects after 6 and 12 months after the intervention. Read more about this study
- Who is it for?
- Ages 65 years and olderHealthy volunteers can take part
- Conditions the study is for
- Old Age; Atrophy, Aging
- What is being tested?
- Experimental group
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 89 participants
- Where
- 1 sitePortugal
- Study dates
- 1 Oct 2021to 31 Jan 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- Healthy volunteers accepted
- Older adult
Who may be able to join
- Participants of both genders;
- Aged 65 years old or more;
- Can walk and perform daily tasks independently and autonomously.
Who cannot join
- People with cognitive impairment;
- People with neurodegenerative diseases;
- People with diabetes disease;
- People with heart/respiratory pathology or use of pacemakers;
- People with musculoskeletal injuries in the 6 months before the study;
- People with active oncology disease;
Show all 9Show fewer
- People with an uncontrolled hypertension (>90 mmHG; >150 mmHg);
- People participate in other supervised exercise program;
- Paeople who refuse to sign the informed consent.
Trial locations and contacts
1 site in 1 country.
Portugal1 site
Department of Sport and Health, School of Health and Human Development, University of Évora
Evora, 7004-516
About this study
Official title: Effects of an High-Speed Resistance Training Program on Health Parameters in Independent Older Adults: a Longitudinal Study
The aims of the present investigation are: a) to determine the effects of a 16-weeks high-speed resistance training program on health parameters in independent older adults; and b) to verify the durability of the effects after 6 and 12 months after the intervention.
Read the detailed description
The present investigation will last a total of 18 months. More specifically, Two weeks for initial assessments, then the 16-weeks training program. After that, there will be a 1-year follow-up.
Regarding the training program, it consists in a high-speed resistance training program of 16-weeks, with three sessions per week (Mondays, Wednesdays, and Fridays) of 50-60min, each session being comprised of five-six exercises, two-three sets, and six-ten reps/exercise. The following exercises are used during the intervention period in pneumatic machines: incline bench press, squat in multipower or with dumbbell, leg extension, seated low row, leg press, calf raise, chest fly and lat pull down.
The intensity is gradually increased after each session in accordance with the movement velocity (>1.3 to 0.75 m/s) representing approximately 20% to 60% of one repetition maximum. Participants execute the exercises rapidly and explosively making all repetitions for each shortening phase (concentric phase) performed as quickly as possible with the lengthening phase of the muscle (eccentric phase) being controlled for 2-3 s. The velocity of the concentric phase in each exercise is monitored through a BEAST™ sensor (Beast Technologies, Brescia, Italy).
Participants unavailable to participate in the intervention period will be allocated to the control group. These participants continue their usual activity without engaging in any resistance training or beginning a new exercise program during the study.
- Conditions
- Old Age; Atrophy, Aging
- Being tested
- Experimental group
- Keywords
- Aging, Older adults, Resistance training, Velocity-based training, Health outcomes, Phase Angle, Gait Variability
- Medical subject headings
- Atrophy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Experimental groupOther
The High-Speed Resistance Training program has 16 weeks, with three sessions per week with 50-60min, each session being comprised of five-six exercises, two-three sets, and six-ten reps/exercise. The intensity is gradually increased after each session in accordance with the movement velocity (>1.3 to 0.75 m/s) representing approximately 20% to 60% of one repetition maximum. Participants execute the exercises rapidly and explosively making all repetitions for each shortening phase (concentric phase) performed as quickly as possible with the lengthening phase of the muscle (eccentric phase) being controlled for 2-3 s. The velocity of the concentric phase in each exercise is monitored through a BEAST™ sensor (Beast Technologies, Brescia, Italy).
| Study group | Role | What they receive |
|---|---|---|
| Experimental group | Experimental | Participants perform a 16-week of High-Speed Resistance Training program. Receives: Other: Experimental group |
| Control group | No intervention | Participantes continued their usual activity without engaging in any strength training or beginning a new exercise program during the study. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Phase angle from bioelectrical impedance
Changes related to cellular health assessed by In Body S10 after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Gait Variability
Changes related to gait variability by Phypox after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Secondary outcomes (10)
Body Composition - Muscle mass; Fat Mass; Body Water.
Changes related to muscle mass, fat mass and body water assessed by In Body S10 and DXA after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Bone Densitometry - Whole-body BMC and BMD and dominant femoral neck BMC and BMD.
Changes related to bone quality assessed by DXA after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Heart Rate Variability
Changes related to autonomous nervous system assessed by Kubios HRV after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Physical Function
Changes related to physical function assessed by four functional fitness tests, namely 30s chair-stand; timed-up \& go test; ball throw and 6 min walk test after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Muscle strength
Changes related to Muscle strength assessed by handgrip test (both sides) and isokinetic dynamometer evaluation (both sides) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Postural control
Changes related to postural control assessed in two conditions (with one foot on the ground and both feet on the ground) by an force platform Add-on (Plux) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Falls Efficacy Scale - International (FES-I)
Changes related to the level of concern about falling during social and physical activities inside and outside the home through a scale (FES-I) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
International Physical Activity Questionnaire (IPAQ)
Changes related to the levels of physical activity through a scale (IPAQ) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Mini-Mental State Examination
Changes related to the cognitive impairment (problems with thinking, communication, understanding and memory) through a scale (MMSE) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
The 36-Item Short Form Survey (SF-36)
Changes related to the health status through a scale (SF-36) after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Measured: 18 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Oct 2022
- Study start1 Oct 2021
- Primary completion1 Feb 2022
- Study completion31 Jan 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Old Age; AtrophyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 89 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Évora
- Sponsor type
- University, hospital or other
- Collaborators
- Polytechnic Institute of Rio Maior, Comprehensive Health Research Center, Foundation for Science and Technology, Portugal, Life Quality Research Center - CIEQV
- Responsible party
- Principal investigator, Alexandre Duarte Martins, University of Évora
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05586087
- Sponsor's protocol ID
- Idade Activa
- Status last verified
- Jun 2024
- First submitted
- 4 Oct 2022
- Last updated
- 1 Jul 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Duarte Martins A, Paulo Brito J, Fernandes O, Oliveira R, Goncalves B, Batalha N. Effects of a 16-week High-Speed Resistance Training program on body composition in community-dwelling independent older adults: A clinical trial. Clin Nutr ESPEN. 2024 Oct;63:84-91. doi: 10.1016/j.clnesp.2024.06.010. Epub 2024 Jun 20.
PubMed 38935496
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of an High-Speed Resistance Training Program on Health Parameters in Independent Older Adults: a Longitudinal Study
- ClinicalTrials.gov ID
- NCT05586087
- Acronym / sponsor ID
- Idade Activa
- Conditions
- Old Age; Atrophy, Aging
- Keywords
- Aging, Older adults, Resistance training, Velocity-based training, Health outcomes, Phase Angle, Gait Variability
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 89 participants (actual)
- Lead sponsor
- University of ÉvoraUniversity, hospital or other
- Collaborators
- Polytechnic Institute of Rio Maior, Comprehensive Health Research Center, Foundation for Science and Technology, Portugal, Life Quality Research Center - CIEQV
- Study start
- 1 Oct 2021 (actual)
- Primary completion
- 1 Feb 2022 (actual)
- Study completion
- 31 Jan 2024 (actual)
- First posted
- 19 Oct 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aims of the present investigation are: a) to determine the effects of a 16-weeks high-speed resistance training program on health parameters in independent older adults; and b) to verify the durability of the effects after 6 and 12 months after the intervention.
Detailed description
The present investigation will last a total of 18 months. More specifically, Two weeks for initial assessments, then the 16-weeks training program. After that, there will be a 1-year follow-up.
Regarding the training program, it consists in a high-speed resistance training program of 16-weeks, with three sessions per week (Mondays, Wednesdays, and Fridays) of 50-60min, each session being comprised of five-six exercises, two-three sets, and six-ten reps/exercise. The following exercises are used during the intervention period in pneumatic machines: incline bench press, squat in multipower or with dumbbell, leg extension, seated low row, leg press, calf raise, chest fly and lat pull down.
The intensity is gradually increased after each session in accordance with the movement velocity (>1.3 to 0.75 m/s) representing approximately 20% to 60% of one repetition maximum. Participants execute the exercises rapidly and explosively making all repetitions for each shortening phase (concentric phase) performed as quickly as possible with the lengthening phase of the muscle (eccentric phase) being controlled for 2-3 s. The velocity of the concentric phase in each exercise is monitored through a BEAST™ sensor (Beast Technologies, Brescia, Italy).
Participants unavailable to participate in the intervention period will be allocated to the control group. These participants continue their usual activity without engaging in any resistance training or beginning a new exercise program during the study.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental group | Experimental | Other: Experimental groupParticipants perform a 16-week of High-Speed Resistance Training program. |
| Control group | No intervention | –Participantes continued their usual activity without engaging in any strength training or beginning a new exercise program during the study. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Older adult
Key inclusion criteria (3 listed)
- Participants of both genders;
- Aged 65 years old or more;
- Can walk and perform daily tasks independently and autonomously.
Key exclusion criteria (9 listed)
- People with cognitive impairment;
- People with neurodegenerative diseases;
- People with diabetes disease;
- People with heart/respiratory pathology or use of pacemakers;
- People with musculoskeletal injuries in the 6 months before the study;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Experimental groupThe High-Speed Resistance Training program has 16 weeks, with three sessions per week with 50-60min, each session being comprised of five-six exercises, two-three sets, and six-ten reps/exercise. The intensity is gradually increased after each session in accordance with the movement velocity (>1.3 to 0.75 m/s) representing approximately 20% to 60% of one repetition maximum. Participants execute the exercises rapidly and explosively making all repetitions for each shortening phase (concentric phase) performed as quickly as possible with the lengthening phase of the muscle (eccentric phase) being controlled for 2-3 s. The velocity of the concentric phase in each exercise is monitored through a BEAST™ sensor (Beast Technologies, Brescia, Italy). | Other | Experimental group |
Primary outcome
Phase angle from bioelectrical impedance
Time frame: 18 months
Changes related to cellular health assessed by In Body S10 after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
Gait Variability
Time frame: 18 months
Changes related to gait variability by Phypox after a 16-weeks high-speed resistance training program and after 6 and 12 moths of the intervention period.
10 secondary outcomes
Body Composition - Muscle mass; Fat Mass; Body Water.
Time frame: 18 months
Bone Densitometry - Whole-body BMC and BMD and dominant femoral neck BMC and BMD.
Time frame: 18 months
Heart Rate Variability
Time frame: 18 months
Physical Function
Time frame: 18 months
Muscle strength
Time frame: 18 months
Postural control
Time frame: 18 months
Falls Efficacy Scale - International (FES-I)
Time frame: 18 months
International Physical Activity Questionnaire (IPAQ)
Time frame: 18 months
Mini-Mental State Examination
Time frame: 18 months
The 36-Item Short Form Survey (SF-36)
Time frame: 18 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2024.
- Derived from this study: PubMed 38935496Duarte Martins A, Paulo Brito J, Fernandes O, Oliveira R, Goncalves B, Batalha N. Effects of a 16-week High-Speed Resistance Training program on body composition in community-dwelling independent older adults: A clinical trial. Clin Nutr ESPEN. 2024 Oct;63:84-91. doi: 10.1016/j.clnesp.2024.06.010. Epub 2024 Jun 20.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Experimental group in people with Old Age; Atrophy and Aging, run by University of Évora at 1 site in Portugal.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 1 Jul 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Portugal. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Phase angle from bioelectrical impedance (time frame: 18 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05586087, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2024.