Smoking, TobaccoNCT05554120
The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluation
An observational study of Smoking, Tobacco and Smoking Behaviors, run by Maastricht University Medical Center at 1 site in Netherlands.
Trial summary
Few countries have legislation to reduce the number and types of tobacco retail outlets. The Netherlands plans to ban tobacco sales in supermarkets in 2024. The overall aim of this proposed research is to evaluate the implementation of new legislation to reduce the number and types of tobacco outlets in the… Read more about this study
- Who is it for?
- Ages 12 years and olderHealthy volunteers can take part
- Conditions the study is for
- Smoking, Tobacco, Smoking Behaviors, Smoking Cessation
- What is being tested?
- Supermarket tobacco sales ban
- How many people
- 1,530 participants
- Where
- 1 siteNetherlands
- Study dates
- 26 Oct 2022to 10 Nov 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Respondents are recruited from NIPObase, a large probability-based access database that mirrors the Dutch population. NIPObase includes over 103,000 respondents in the general population who regularly participate in surveys from Kantar. With NIPObase the investigators are able to draw samples that are representative of the Dutch population according to known characteristics such as gender, age, geographic region, and household size.
Who may be able to join
- Dutch-speaking
- aged 12 to 17 years old at enrollment
- Dutch-speaking
- smoking at least monthly at enrollment
- having smoked at least 100 cigarettes in their lifetime
Who cannot join
- they have smoked (part of) a cigarette at least once a month during the last six months
- not providing informed consent to participate
- Smoking adults
- not providing informed consent to participate
Trial locations and contacts
1 site in 1 country.
About this study
Few countries have legislation to reduce the number and types of tobacco retail outlets. The Netherlands plans to ban tobacco sales in supermarkets in 2024. The overall aim of this proposed research is to evaluate the implementation of new legislation to reduce the number and types of tobacco outlets in the Netherlands, up until and including the ban on sales of tobacco in supermarkets.
In a comprehensive policy evaluation, the investigators plan to examine (1) the impact of the policy on the number and types of tobacco outlets, (2) the impact on attitudes and behaviors of smoking adults and non-smoking youth, and (3) the influence of the tobacco industry on the policy process and the retail environment. In addition, the investigators plan to focus on differential effects in disadvantaged neighborhoods, where both smoking rates and tobacco outlet density are typically highest.
Read more
The investigators bring together a unique combination of economic, psychological, and journalistic research methods. The investigators examine the impact of the new legislation on the amount and type of tobacco outlets and on the number of smokers by using routinely collected monitoring data. The investigators examine the impact of the legislation on smoking susceptibility of non-smoking youth and on impulse tobacco purchases by smoking adults with yearly quantitative surveys (two surveys before the policy implementation and two after) and with qualitative interviews and discussion sessions. The investigators examine whether these impacts differ for disadvantaged versus non-disadvantaged neighborhoods. The investigators examine what strategies the tobacco industry uses to influence the new legislation, policy processes, and the tobacco retail environment by performing a journalistic investigation, using for example documents obtained by Freedom of Information Act requests, (possibly) leaked documents from insider meetings, and interviews with insiders.
Our research will provide a comprehensive evaluation of the effects of the implementation of the proposed legislative measures. Based on our results, the investigators will formulate recommendations for the Dutch Cancer Society, the Dutch government, and for other countries who consider reducing the number of tobacco outlets; highlight potential areas for further development and improvement within the legislative framework and provide recommendations on how to counter the lobby from the tobacco industry.
Read the detailed description
Problem description: Tobacco use is the primary cause of several cancers; among them lung cancer, which is the leading preventable cause of death in the Netherlands. Yet, tobacco use remains high in the Netherlands, with an adult smoking prevalence of 20%, which is even higher in groups with a lower socioeconomic position. Therefore, reducing the smoking prevalence in all groups in society is one of the three priorities in the Dutch National Prevention Agreement. This Agreement was made with the Dutch government and more than 70 societal organizations, including the Dutch Cancer Society. It consists of a range of voluntary agreements and policy measures to reduce smoking prevalence to 5% or less by 2040. Among these measures is the proposal to reduce the number of outlets that sell tobacco. The government has announced a stepwise approach to ban the sales of tobacco products from various types of outlets. The first step is planned for 2022, with a ban on cigarette dispensing machines. This is followed by a ban on the online sale of tobacco in 2023. In 2024, the largest change is planned with a ban on the sales of tobacco for supermarkets, which currently accounts for approximately 40% of tobacco outlets in the Netherlands. The last step is to phase out the sale of tobacco at petrol stations and convenience stores, so that in the end only specialist tobacco shops can sell tobacco products. The reasoning of the Dutch government for this legislation is to protect young (non-)smokers and adult (former) smokers from exposure to tobacco products and with that from the temptation to smoke and to make impulse purchases, ultimately making it easier to quit smoking and less likely to (re-)initiate smoking. It also adds to the denormalization of smoking as it makes tobacco products disappear from common sight. The proposed measures however lack clear goals, such as a target number of tobacco outlets, nor is there any particular attention given to reducing socioeconomic inequalities in smoking through these measures. Moreover, the tobacco industry is known to try to stop, delay, or weaken legislation before it is implemented, and may try to influence the tobacco retail environment.
Research direction: The investigators will do a comprehensive policy evaluation of the new Dutch legislation on tobacco outlets. The investigators examine:
- The effects of the legislation on the number of tobacco sales outlets.
- The effects of the reduced number of sales outlets (if any) on the number of smokers.
- The effects on smoking susceptibility among non-smoking youth.
- The effects on impulse tobacco purchases of smoking adults.
- How these impacts differ for those living in disadvantaged versus non-disadvantaged neighborhoods.
- The strategies that the tobacco industry uses to influence the national legislation on tobacco outlets.
- And the strategies that the tobacco industry uses to influence the tobacco retail environment in the Netherlands.
Aim: The overall aim of this proposed research is to evaluate the implementation of new legislation to reduce the number and types of tobacco outlets in the Netherlands, up until and including the ban on sales of tobacco in supermarkets.
Primary research questions are:
What is the impact of the new legislation on the number and type of tobacco outlets? What is the impact of the new legislation by supermarkets on the number of smokers? What is the impact of the new legislation on smoking susceptibility of non-smoking youth? What is the impact of the new legislation on impulse tobacco purchases by smoking adults? Does this impact differ for smoking adults living in disadvantaged versus non-disadvantaged neighborhoods? What strategies does the tobacco industry use to influence the new legislation and policy processes? What strategies does the tobacco industry use to influence the tobacco retail environment?
Secondary research questions are:
How do non-smoking youth and smoking adults experience the new legislation? To what extent does the new legislation lead to more illegal (online) sales of tobacco and what is the role of the tobacco industry in this? What is the impact of the new legislation on use and marketing of 'reduced risk' products such as electronic cigarettes and heated tobacco?
Expected outcome: Our research will provide a comprehensive evaluation of the effects of the implementation of the proposed measures on the reduction of tobacco outlets. The four organizations that carry out this research have worked closely together in the past on comparable research projects and will ensure that the three parts of the project will come together to provide a comprehensive picture. Based on our results, the investigators will formulate recommendations for the Dutch Cancer Society, the Dutch government, and for other countries who consider reducing the number of tobacco outlets. The investigators will highlight potential areas for further development and improvement within the legislative framework and provide recommendations on how to counter the lobby from the tobacco industry.
Plan of Investigation:
The proposed research consists of three parts:
- In the first part, the investigators examine the effects of the legislation on the number of tobacco sales outlets. The investigators also study the effects of the reduced number of sales outlets (if any) on the number of smokers. Both are examined separately for disadvantaged and non-disadvantaged neighborhoods. For this work package the investigators rely on existing data on retail locations and smoking prevalence. The investigators use data from 2018 to 2025 to account for existing trends. This part will be carried out by a research institute that specializes in economic analyses (SEO Amsterdam Economic) sand has done previous analyses with sales outlet and smoking prevalence data.
- In the second part, the investigators examine the effects of the legislation on smoking susceptibility among nonsmoking youth and on impulse tobacco purchases of smoking adults. The investigators also examine how the effects differ for smoking adults living in disadvantaged versus non-disadvantaged neighborhoods. The investigators will conduct yearly, quantitative survey waves from 2022 to 2025 among a cohort of 250 non-smoking youth, 600 smoking adults from disadvantaged neighborhoods, and 600 smoking adults from non-disadvantaged neighborhoods. The investigators will also carry out in-depth qualitative interviews and discussion sessions with non-smoking youth and smoking adults from these three groups. This part will be carried out by a research institute that specializes in mixed-methods addiction research (IVO research Institute) and focuses on vulnerable groups in society, together with a university department of Health Promotion (Maastricht University) that has ample experience with tobacco control policy evaluations.
- In the third part, the investigators examine the strategies of the tobacco industry to influence both the national legislation on tobacco outlets, and to influence the tobacco retail environment. The investigators use investigative journalism techniques to uncover lobbying strategies and tactics of the tobacco industry and their allies. The investigators use a wide range of sources: documents obtained by FOIA-requests, (possibly) leaked documents from insider meetings, (background) interviews with insiders of the tobacco industry, the government, and the retail sector, the analysis of social media campaigns, financial and marketing data, and observations of tobacco outlets (online and offline). This part will be carried out by an organization of investigative journalists that specializes in the strategies and tactics of the tobacco industry (The Investigative Desk).
- Being tested
- Supermarket tobacco sales ban
- Keywords
- Tobacco, Policy evaluation, Social class, Supermarkets
- Medical subject headings
- Tobacco Smoking, Smoking, Smoking Cessation, Smoking Reduction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Supermarket tobacco sales banOther
In 2024, a ban on the sales of tobacco for supermarkets is planned by the Dutch government. Supermarkets accounted for approximately 40% of tobacco outlets in the Netherlands in 2021.
| Study group | Role | What they receive |
|---|---|---|
| Non-smoking adolescents | Non-smoking youth aged 12-17 years old. As the investigators monitor the cohort, it is possible that some of the cohort will become smokers. Receives: Other: Supermarket tobacco sales ban | |
| Smoking adults from disadvantaged neighbourhoods | Smoking adults aged 18 years and older from disadvantaged neighbourhoods. The investigators distinguish between disadvantaged and non-disadvantaged neighborhoods by using data from CBS Statistics Netherlands (CBS). Receives: Other: Supermarket tobacco sales ban | |
| Smoking adults from non-disadvantaged neighbourhoods | Smoking adults aged 18 years and older from non-disadvantaged neighbourhoods. The investigators distinguish between disadvantaged and non-disadvantaged neighborhoods by using data from CBS Statistics Netherlands (CBS). Receives: Other: Supermarket tobacco sales ban |
What is being measured
The primary outcome is the main question the study is designed to answer.
Impulse purchases of tobacco
This is measured amongst smoking adults with the question "When you are shopping in a store in your neighborhood for something other than cigarettes, how often do you decide to buy cigarettes?" (1=Often, 2=Rarely, 3=Sometimes, 4=Often, 5=Always) (Siahpush et al., 2016).
Measured: October 2022; October-November 2023, 2024, 2025
Smoking susceptibility
This is measured amongst non-smoking adolescents with a three-item index, averaging responses to "Would you try smoking a cigarette if one of your best friends offered it to you?", "Do you think you would smoke in the next 6 months?", and "Are you curious about smoking?" (1=Definitely Not, 2=Probably Not, 3=Probably Yes, 4=Definitely Yes) (Strong et al., 2015).
Measured: October 2022; October-November 2023, 2024, 2025
Number of smokers
The investigators use data at the individual level. The investigators propose to use existing data from the lifestyle monitor of CBS (15,000 observations annually) and the polling station survey among students (8,000 observations every four years). For each individual the investigators link the area where they live.
Measured: 2018-2025
Secondary outcomes (3)
Illegal (online) sales of tobacco
The investigators will ask our adult cohort if they have "bought cigarettes or tobacco during the past 6 months from people who sell cigarettes or tobacco independently, for example at the door or on the street" and the frequency of which they do so.
The investigators will also do observations on the Internet, for mapping the developments in (online) sales, possibly also via 'scraping'. This technique involves systematically gathering and arranging data from a large number of websites and provides insight into the development of the number of (online) sales sites, of product pricing, of changes in product availability and of the overall 'traffic' (visitor amount) of these websites, indicating (legal or illegal) shopping activities.
Measured: October 2022; October-November 2023, 2024, 2025
Use and marketing of 'reduced risk' products
The investigators adopt a wide definition of 'reduced risk' products. The use of the products will be measured in our cohort and with investigative journalism methods. Marketing of the products will also be explored with investigative journalism methods.
Measured: October 2022; October-November 2023, 2024, 2025
Number and type of tobacco outlets
For the number and type of tobacco outlets the investigators rely on existing data from Locatus. Locatus is a company which collects information about retail locations on a daily basis by professional field service.
They can distinguish the following types of outlets:
- Supermarkets
- Mini supermarkets
- Petrol stations (staffed)
- Convenience stores: they sell tobacco and convenience articles like journals, lottery tickets, office supplies, greeting cards, telephone accessories and candies
- Specialist tobacco shops (with more than 70% of turnover from tobacco sales)
- Night shops.
Measured: 2018-2025
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Sep 2022
- Study start26 Oct 2022
- Primary completion10 Nov 2025
- Study completion10 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Smoking, TobaccoStudies of the same condition, open and under way.
- More trials run by Maastricht University Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,530 participants (actual)
Sponsor and investigators
- Lead sponsor
- Maastricht University Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- The Investigative Desk, SEO Amsterdam Economics, IVO Research Institute
- Responsible party
- Sponsor
- Investigators
- Gera E Nagelhout, PhD, Principal investigator, Maastricht University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT05554120
- Sponsor's protocol ID
- KWF140282021-2
- Status last verified
- Oct 2026
- First submitted
- 21 Sep 2022
- Last updated
- 22 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Siahpush M, Shaikh RA, Hyland A, Smith D, Sikora Kessler A, Meza J, Wan N, Wakefield M. Point-of-Sale Cigarette Marketing, Urge to Buy Cigarettes, and Impulse Purchases of Cigarettes: Results From a Population-Based Survey. Nicotine Tob Res. 2016 May;18(5):1357-62. doi: 10.1093/ntr/ntv181. Epub 2015 Sep 16.
PubMed 26377520Strong DR, Hartman SJ, Nodora J, Messer K, James L, White M, Portnoy DB, Choiniere CJ, Vullo GC, Pierce J. Predictive Validity of the Expanded Susceptibility to Smoke Index. Nicotine Tob Res. 2015 Jul;17(7):862-9. doi: 10.1093/ntr/ntu254. Epub 2014 Dec 6.
PubMed 25481915Nagelhout GE, Poole NL, Metze M, Willemsen MC, Vermeulen W, van den Brand FA. Reducing the number and types of tobacco retail outlets in the Netherlands: Study protocol for a comprehensive mixedmethods policy evaluation. Tob Prev Cessat. 2023 Mar 29;9:08. doi: 10.18332/tpc/161825. eCollection 2023.
PubMed 37009236
Study at a glance
From the registry record, last updated by the sponsor on 22 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Next Step in Smoking Prevention: the Reduction of Tobacco Retail Outlets, a Comprehensive Policy Evaluation
- ClinicalTrials.gov ID
- NCT05554120
- Acronym / sponsor ID
- KWF140282021-2
- Keywords
- Tobacco, Policy evaluation, Social class, Supermarkets
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,530 participants (actual)
- Lead sponsor
- Maastricht University Medical CenterUniversity, hospital or other
- Collaborators
- The Investigative Desk, SEO Amsterdam Economics, IVO Research Institute
- Study start
- 26 Oct 2022 (actual)
- Primary completion
- 10 Nov 2025 (actual)
- Study completion
- 10 Nov 2025 (actual)
- First posted
- 26 Sep 2022 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Few countries have legislation to reduce the number and types of tobacco retail outlets. The Netherlands plans to ban tobacco sales in supermarkets in 2024. The overall aim of this proposed research is to evaluate the implementation of new legislation to reduce the number and types of tobacco outlets in the Netherlands, up until and including the ban on sales of tobacco in supermarkets.
In a comprehensive policy evaluation, the investigators plan to examine (1) the impact of the policy on the number and types of tobacco outlets, (2) the impact on attitudes and behaviors of smoking adults and non-smoking youth, and (3) the influence of the tobacco industry on the policy process and the retail environment. In addition, the investigators plan to focus on differential effects in disadvantaged neighborhoods, where both smoking rates and tobacco outlet density are typically highest.
The investigators bring together a unique combination of economic, psychological, and journalistic research methods. The investigators examine the impact of the new legislation on the amount and type of tobacco outlets and on the number of smokers by using routinely collected monitoring data. The investigators examine the impact of the legislation on smoking susceptibility of non-smoking youth and on impulse tobacco purchases by smoking adults with yearly quantitative surveys (two surveys before the policy implementation and two after) and with qualitative interviews and discussion sessions. The investigators examine whether these impacts differ for disadvantaged versus non-disadvantaged neighborhoods. The investigators examine what strategies the tobacco industry uses to influence the new legislation, policy processes, and the tobacco retail environment by performing a journalistic investigation, using for example documents obtained by Freedom of Information Act requests, (possibly) leaked documents from insider meetings, and interviews with insiders.
Our research will provide a comprehensive evaluation of the effects of the implementation of the proposed legislative measures. Based on our results, the investigators will formulate recommendations for the Dutch Cancer Society, the Dutch government, and for other countries who consider reducing the number of tobacco outlets; highlight potential areas for further development and improvement within the legislative framework and provide recommendations on how to counter the lobby from the tobacco industry.
Detailed description
Problem description: Tobacco use is the primary cause of several cancers; among them lung cancer, which is the leading preventable cause of death in the Netherlands. Yet, tobacco use remains high in the Netherlands, with an adult smoking prevalence of 20%, which is even higher in groups with a lower socioeconomic position. Therefore, reducing the smoking prevalence in all groups in society is one of the three priorities in the Dutch National Prevention Agreement. This Agreement was made with the Dutch government and more than 70 societal organizations, including the Dutch Cancer Society. It consists of a range of voluntary agreements and policy measures to reduce smoking prevalence to 5% or less by 2040. Among these measures is the proposal to reduce the number of outlets that sell tobacco. The government has announced a stepwise approach to ban the sales of tobacco products from various types of outlets. The first step is planned for 2022, with a ban on cigarette dispensing machines. This is followed by a ban on the online sale of tobacco in 2023. In 2024, the largest change is planned with a ban on the sales of tobacco for supermarkets, which currently accounts for approximately 40% of tobacco outlets in the Netherlands. The last step is to phase out the sale of tobacco at petrol stations and convenience stores, so that in the end only specialist tobacco shops can sell tobacco products. The reasoning of the Dutch government for this legislation is to protect young (non-)smokers and adult (former) smokers from exposure to tobacco products and with that from the temptation to smoke and to make impulse purchases, ultimately making it easier to quit smoking and less likely to (re-)initiate smoking. It also adds to the denormalization of smoking as it makes tobacco products disappear from common sight. The proposed measures however lack clear goals, such as a target number of tobacco outlets, nor is there any particular attention given to reducing socioeconomic inequalities in smoking through these measures. Moreover, the tobacco industry is known to try to stop, delay, or weaken legislation before it is implemented, and may try to influence the tobacco retail environment.
Research direction: The investigators will do a comprehensive policy evaluation of the new Dutch legislation on tobacco outlets. The investigators examine:
- The effects of the legislation on the number of tobacco sales outlets.
- The effects of the reduced number of sales outlets (if any) on the number of smokers.
- The effects on smoking susceptibility among non-smoking youth.
- The effects on impulse tobacco purchases of smoking adults.
- How these impacts differ for those living in disadvantaged versus non-disadvantaged neighborhoods.
- The strategies that the tobacco industry uses to influence the national legislation on tobacco outlets.
- And the strategies that the tobacco industry uses to influence the tobacco retail environment in the Netherlands.
Aim: The overall aim of this proposed research is to evaluate the implementation of new legislation to reduce the number and types of tobacco outlets in the Netherlands, up until and including the ban on sales of tobacco in supermarkets.
Primary research questions are:
What is the impact of the new legislation on the number and type of tobacco outlets? What is the impact of the new legislation by supermarkets on the number of smokers? What is the impact of the new legislation on smoking susceptibility of non-smoking youth? What is the impact of the new legislation on impulse tobacco purchases by smoking adults? Does this impact differ for smoking adults living in disadvantaged versus non-disadvantaged neighborhoods? What strategies does the tobacco industry use to influence the new legislation and policy processes? What strategies does the tobacco industry use to influence the tobacco retail environment?
Secondary research questions are:
How do non-smoking youth and smoking adults experience the new legislation? To what extent does the new legislation lead to more illegal (online) sales of tobacco and what is the role of the tobacco industry in this? What is the impact of the new legislation on use and marketing of 'reduced risk' products such as electronic cigarettes and heated tobacco?
Expected outcome: Our research will provide a comprehensive evaluation of the effects of the implementation of the proposed measures on the reduction of tobacco outlets. The four organizations that carry out this research have worked closely together in the past on comparable research projects and will ensure that the three parts of the project will come together to provide a comprehensive picture. Based on our results, the investigators will formulate recommendations for the Dutch Cancer Society, the Dutch government, and for other countries who consider reducing the number of tobacco outlets. The investigators will highlight potential areas for further development and improvement within the legislative framework and provide recommendations on how to counter the lobby from the tobacco industry.
Plan of Investigation:
The proposed research consists of three parts:
- In the first part, the investigators examine the effects of the legislation on the number of tobacco sales outlets. The investigators also study the effects of the reduced number of sales outlets (if any) on the number of smokers. Both are examined separately for disadvantaged and non-disadvantaged neighborhoods. For this work package the investigators rely on existing data on retail locations and smoking prevalence. The investigators use data from 2018 to 2025 to account for existing trends. This part will be carried out by a research institute that specializes in economic analyses (SEO Amsterdam Economic) sand has done previous analyses with sales outlet and smoking prevalence data.
- In the second part, the investigators examine the effects of the legislation on smoking susceptibility among nonsmoking youth and on impulse tobacco purchases of smoking adults. The investigators also examine how the effects differ for smoking adults living in disadvantaged versus non-disadvantaged neighborhoods. The investigators will conduct yearly, quantitative survey waves from 2022 to 2025 among a cohort of 250 non-smoking youth, 600 smoking adults from disadvantaged neighborhoods, and 600 smoking adults from non-disadvantaged neighborhoods. The investigators will also carry out in-depth qualitative interviews and discussion sessions with non-smoking youth and smoking adults from these three groups. This part will be carried out by a research institute that specializes in mixed-methods addiction research (IVO research Institute) and focuses on vulnerable groups in society, together with a university department of Health Promotion (Maastricht University) that has ample experience with tobacco control policy evaluations.
- In the third part, the investigators examine the strategies of the tobacco industry to influence both the national legislation on tobacco outlets, and to influence the tobacco retail environment. The investigators use investigative journalism techniques to uncover lobbying strategies and tactics of the tobacco industry and their allies. The investigators use a wide range of sources: documents obtained by FOIA-requests, (possibly) leaked documents from insider meetings, (background) interviews with insiders of the tobacco industry, the government, and the retail sector, the analysis of social media campaigns, financial and marketing data, and observations of tobacco outlets (online and offline). This part will be carried out by an organization of investigative journalists that specializes in the strategies and tactics of the tobacco industry (The Investigative Desk).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Non-smoking adolescents | – | Other: Supermarket tobacco sales banNon-smoking youth aged 12-17 years old. As the investigators monitor the cohort, it is possible that some of the cohort will become smokers. |
| Smoking adults from disadvantaged neighbourhoods | – | Other: Supermarket tobacco sales banSmoking adults aged 18 years and older from disadvantaged neighbourhoods. The investigators distinguish between disadvantaged and non-disadvantaged neighborhoods by using data from CBS Statistics Netherlands (CBS). |
| Smoking adults from non-disadvantaged neighbourhoods | – | Other: Supermarket tobacco sales banSmoking adults aged 18 years and older from non-disadvantaged neighbourhoods. The investigators distinguish between disadvantaged and non-disadvantaged neighborhoods by using data from CBS Statistics Netherlands (CBS). |
Who may qualify
- Ages
- 12 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Respondents are recruited from NIPObase, a large probability-based access database that mirrors the Dutch population. NIPObase includes over 103,000 respondents in the general population who regularly participate in surveys from Kantar. With NIPObase the investigators are able to draw samples that are representative of the Dutch population according to known characteristics such as gender, age, geographic region, and household size.
Key inclusion criteria (5 listed)
- Dutch-speaking
- aged 12 to 17 years old at enrollment
- Dutch-speaking
- smoking at least monthly at enrollment
- having smoked at least 100 cigarettes in their lifetime
Key exclusion criteria (4 listed)
- they have smoked (part of) a cigarette at least once a month during the last six months
- not providing informed consent to participate
- Smoking adults
- not providing informed consent to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Supermarket tobacco sales banIn 2024, a ban on the sales of tobacco for supermarkets is planned by the Dutch government. Supermarkets accounted for approximately 40% of tobacco outlets in the Netherlands in 2021. | Other | Non-smoking adolescents, Smoking adults from disadvantaged neighbourhoods, Smoking adults from non-disadvantaged neighbourhoods |
Primary outcome
Impulse purchases of tobacco
Time frame: October 2022; October-November 2023, 2024, 2025
This is measured amongst smoking adults with the question "When you are shopping in a store in your neighborhood for something other than cigarettes, how often do you decide to buy cigarettes?" (1=Often, 2=Rarely, 3=Sometimes, 4=Often, 5=Always) (Siahpush et al., 2016).
Smoking susceptibility
Time frame: October 2022; October-November 2023, 2024, 2025
This is measured amongst non-smoking adolescents with a three-item index, averaging responses to "Would you try smoking a cigarette if one of your best friends offered it to you?", "Do you think you would smoke in the next 6 months?", and "Are you curious about smoking?" (1=Definitely Not, 2=Probably Not, 3=Probably Yes, 4=Definitely Yes) (Strong et al., 2015).
Number of smokers
Time frame: 2018-2025
The investigators use data at the individual level. The investigators propose to use existing data from the lifestyle monitor of CBS (15,000 observations annually) and the polling station survey among students (8,000 observations every four years). For each individual the investigators link the area where they live.
3 secondary outcomes
Illegal (online) sales of tobacco
Time frame: October 2022; October-November 2023, 2024, 2025
Use and marketing of 'reduced risk' products
Time frame: October 2022; October-November 2023, 2024, 2025
Number and type of tobacco outlets
Time frame: 2018-2025
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Oct 2026.
- Background: PubMed 26377520Siahpush M, Shaikh RA, Hyland A, Smith D, Sikora Kessler A, Meza J, Wan N, Wakefield M. Point-of-Sale Cigarette Marketing, Urge to Buy Cigarettes, and Impulse Purchases of Cigarettes: Results From a Population-Based Survey. Nicotine Tob Res. 2016 May;18(5):1357-62. doi: 10.1093/ntr/ntv181. Epub 2015 Sep 16.
- Background: PubMed 25481915Strong DR, Hartman SJ, Nodora J, Messer K, James L, White M, Portnoy DB, Choiniere CJ, Vullo GC, Pierce J. Predictive Validity of the Expanded Susceptibility to Smoke Index. Nicotine Tob Res. 2015 Jul;17(7):862-9. doi: 10.1093/ntr/ntu254. Epub 2014 Dec 6.
- Derived from this study: PubMed 37009236Nagelhout GE, Poole NL, Metze M, Willemsen MC, Vermeulen W, van den Brand FA. Reducing the number and types of tobacco retail outlets in the Netherlands: Study protocol for a comprehensive mixedmethods policy evaluation. Tob Prev Cessat. 2023 Mar 29;9:08. doi: 10.18332/tpc/161825. eCollection 2023.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Gera E Nagelhout, PhD principal investigator
Maastricht University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Smoking, Tobacco and Smoking Behaviors, run by Maastricht University Medical Center at 1 site in Netherlands.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Impulse purchases of tobacco (time frame: October 2022; October-November 2023, 2024, 2025). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT05554120, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Oct 2026.